PMC:7281546 / 53054-53699 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7281546","sourcedb":"PMC","sourceid":"7281546","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7281546","text":"Porcine epidemic diarrhea virus (PEDV) genome constitution. The viral genome is composed of seven open reading frames (ORFs) and the 5′ and 3′ untranslated regions (UTRs). The ORFs encode four structure proteins (S, E, M and N), a hypothetical accessory protein (ORF3), as well as 16 nsps (nsp1–16). Nsp3 contains two papain-like proteases domains (PLP1 and PLP2). Definitions: 3CLpro, 3C-like protease (nsp5); RdRp, RNA-dependent RNA polymerase (nsp12); HEL, 5′-to-3′ Helicase (nsp13); ExoN, 3′-to-5′ exoribonuclease (nsp14); N7-MTase, N7-methyl transferase (nsp14); EndoU, endoribonuclease (nsp15); 2′-O-MTase, 2′-O-methyl transferase 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