PMC:7281546 / 51016-52413
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T309 | 394-402 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T310 | 422-430 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T311 | 543-550 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T312 | 686-694 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T313 | 772-780 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T314 | 880-887 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T315 | 977-985 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T316 | 1085-1087 | Body_part | denotes | ER | http://purl.org/sig/ont/fma/fma63842 |
| T317 | 1096-1100 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T115 | 52-65 | Disease | denotes | infections in | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T486 | 20-23 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T487 | 104-107 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T488 | 115-116 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T489 | 225-234 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T490 | 320-329 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T491 | 764-766 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T492 | 865-874 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T493 | 913-916 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T494 | 1096-1100 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T495 | 1156-1161 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T8400 | 225-244 | Chemical | denotes | signaling molecules | http://purl.obolibrary.org/obo/CHEBI_62488 |
| T14097 | 235-244 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T82131 | 394-402 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T14813 | 422-430 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T90443 | 466-477 | Chemical | denotes | antagonists | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T63691 | 543-550 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T46155 | 686-694 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T17979 | 772-780 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T84679 | 820-831 | Chemical | denotes | antagonists | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T52253 | 880-887 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T21929 | 977-985 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T401 | 225-244 | http://purl.obolibrary.org/obo/GO_0048018 | denotes | signaling molecules |
| T402 | 225-234 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T403 | 320-338 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T404 | 320-329 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T405 | 565-586 | http://purl.obolibrary.org/obo/GO_0032606 | denotes | type I IFN production |
| T406 | 706-727 | http://purl.obolibrary.org/obo/GO_0032606 | denotes | type I IFN production |
| T407 | 865-874 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T408 | 1101-1110 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T409 | 1101-1110 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T410 | 1112-1121 | http://purl.obolibrary.org/obo/GO_0016236 | denotes | autophagy |
| T411 | 1112-1121 | http://purl.obolibrary.org/obo/GO_0006914 | denotes | autophagy |
| T412 | 1156-1179 | http://purl.obolibrary.org/obo/GO_0019048 | denotes | virus-host interactions |
| T413 | 1289-1302 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T383 | 0-2 | Sentence | denotes | 5. |
| T384 | 3-14 | Sentence | denotes | Conclusions |
| T385 | 15-161 | Sentence | denotes | PEDV has caused epidemic and endemic infections in pig populations in many countries and has become a major economic threat to the swine industry. |
| T386 | 162-370 | Sentence | denotes | Previous studies have identified viral factors that target key signaling molecules in the RLRs’ pathways, as well as viral factors that target the downstream signaling pathways responsible for ISGs induction. |
| T387 | 371-486 | Sentence | denotes | Of the 23 PEDV-encoded proteins, at least 10 viral proteins have been identified as type I IFN antagonists [65,78]. |
| T388 | 487-637 | Sentence | denotes | The mechanisms utilized by PEDV nsp1, PLP2, nsp5, and N protein to antagonize type I IFN production have been clarified (Figure 3, [58,65,78,80,129]). |
| T389 | 638-751 | Sentence | denotes | However, the specific mechanisms of other viral proteins to inhibit type I IFN production remain largely unknown. |
| T390 | 752-832 | Sentence | denotes | At present, 11 PEDV proteins have been identified as type III IFNs’ antagonists. |
| T391 | 833-1018 | Sentence | denotes | The suppression of type III IFN signaling by N protein, nsp1, as well as nsp15, has been reported, while the mechanisms utilized by these viral proteins need to be further investigated. |
| T392 | 1019-1209 | Sentence | denotes | In addition, the CoVs replication cycle may induce the changes of ER stress, cell apoptosis, autophagy pathways, which contain intricate virus-host interactions and cross-talk relationships. |
| T393 | 1210-1312 | Sentence | denotes | Thus, more researches for PEDV are needed to truly reflect viral evasions from innate immune defenses. |
| T394 | 1313-1397 | Sentence | denotes | The findings of PEDV-host interactions will help prevent and control PEDV spreading. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32403318-26773386-82827507 | 479-481 | 26773386 | denotes | 65 |
| 32403318-28715653-82827508 | 482-484 | 28715653 | denotes | 78 |
| 32403318-24872591-82827509 | 619-621 | 24872591 | denotes | 58 |
| 32403318-26773386-82827510 | 622-624 | 26773386 | denotes | 65 |
| 32403318-28715653-82827511 | 625-627 | 28715653 | denotes | 78 |
| 32403318-23596270-82827512 | 628-630 | 23596270 | denotes | 80 |
| 32403318-28045037-82827513 | 631-634 | 28045037 | denotes | 129 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1721 | 519-523 | Gene | denotes | nsp1 | Gene:10045 |
| 1722 | 525-529 | Gene | denotes | PLP2 | Gene:5355 |
| 1723 | 531-535 | Gene | denotes | nsp5 | Gene:92521 |
| 1724 | 889-893 | Gene | denotes | nsp1 | Gene:10045 |
| 1725 | 15-19 | Species | denotes | PEDV | Tax:28295 |
| 1726 | 66-69 | Species | denotes | pig | Tax:9823 |
| 1727 | 146-151 | Species | denotes | swine | Tax:9823 |
| 1728 | 381-385 | Species | denotes | PEDV | Tax:28295 |
| 1729 | 514-518 | Species | denotes | PEDV | Tax:28295 |
| 1730 | 767-771 | Species | denotes | PEDV | Tax:28295 |
| 1731 | 1036-1040 | Species | denotes | CoVs | Tax:11118 |
| 1732 | 1236-1240 | Species | denotes | PEDV | Tax:28295 |
| 1733 | 1329-1333 | Species | denotes | PEDV | Tax:28295 |
| 1734 | 1382-1386 | Species | denotes | PEDV | Tax:28295 |
| 1735 | 355-359 | Chemical | denotes | ISGs | |
| 1736 | 52-62 | Disease | denotes | infections | MESH:D007239 |
| 1737 | 1088-1094 | Disease | denotes | stress | MESH:D000079225 |