PMC:7281546 / 26001-26864
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T158 | 174-185 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T159 | 310-314 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T233 | 150-156 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T234 | 286-295 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T235 | 310-314 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T236 | 513-516 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T237 | 595-605 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T238 | 651-652 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T239 | 664-665 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T240 | 805-806 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T185 | 166-169 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T186 | 190-192 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T188 | 199-202 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T189 | 207-209 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T191 | 216-219 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T192 | 224-226 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T194 | 237-240 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T195 | 647-649 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
| T198 | 687-690 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T199 | 780-783 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T200 | 801-803 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
| T203 | 842-845 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T151 | 108-131 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune responses |
| T152 | 286-304 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T153 | 286-295 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T154 | 310-325 | http://purl.obolibrary.org/obo/GO_0010467 | denotes | gene expression |
| T155 | 550-573 | http://purl.obolibrary.org/obo/GO_0000981 | denotes | transcriptional factors |
| T156 | 550-565 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T183 | 0-132 | Sentence | denotes | Type III IFNs have been explored in recent years, to unravel the underlying mechanisms that manipulate host innate immune responses. |
| T184 | 133-258 | Sentence | denotes | Type III IFNs in humans contains IFN-λ1 (interleukin 29 [IL-29]), IFN-λ2 (IL-28A), IFN-λ3 (IL-28B), and IFN-λ4 [160,161,162]. |
| T185 | 259-365 | Sentence | denotes | Their expression profiles, signaling pathways, and gene expression programs resemble those of type I IFNs. |
| T186 | 366-518 | Sentence | denotes | The production of type I and III IFNs are both initiated through the recognition of PAMPs or damage associated molecular patterns (DAMPs) by PRRs [163]. |
| T187 | 519-763 | Sentence | denotes | Despite the fact that the same transcriptional factors are required for the activation of promoters of type I and III IFNs, the NF-κB pathway is a pivotal regulator in IFN-λ production, whereas the IRFs pathway dominates type I IFNs expression. |
| T188 | 764-863 | Sentence | denotes | The promoter of IFN-λ1 includes more NF-κB binding sites compared with in the IFN-β promoter [164]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32403318-24751921-82827383 | 245-248 | 24751921 | denotes | 160 |
| 32403318-12483210-82827384 | 249-252 | 12483210 | denotes | 161 |
| 32403318-23291588-82827385 | 253-256 | 23291588 | denotes | 162 |
| 32403318-19686699-82827386 | 513-516 | 19686699 | denotes | 163 |
| 32403318-19570999-82827387 | 858-861 | 19570999 | denotes | 164 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 770 | 166-172 | Gene | denotes | IFN-λ1 | Gene:282618 |
| 771 | 174-188 | Gene | denotes | interleukin 29 | Gene:282618 |
| 772 | 190-195 | Gene | denotes | IL-29 | Gene:282618 |
| 773 | 199-205 | Gene | denotes | IFN-λ2 | Gene:282616 |
| 774 | 207-213 | Gene | denotes | IL-28A | Gene:282616 |
| 775 | 216-222 | Gene | denotes | IFN-λ3 | Gene:282617 |
| 776 | 224-230 | Gene | denotes | IL-28B | Gene:282617 |
| 777 | 237-243 | Gene | denotes | IFN-λ4 | Gene:282617 |
| 778 | 647-652 | Gene | denotes | NF-κB | Gene:4790 |
| 779 | 780-786 | Gene | denotes | IFN-λ1 | Gene:282618 |
| 780 | 801-806 | Gene | denotes | NF-κB | Gene:4790 |
| 781 | 842-847 | Gene | denotes | IFN-β | Gene:3439 |
| 782 | 687-690 | Gene | denotes | IFN | Gene:3439 |
| 783 | 150-156 | Species | denotes | humans | Tax:9606 |