PMC:7279430 / 8963-10046 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"371","span":{"begin":175,"end":194},"obj":"Species"},{"id":"372","span":{"begin":553,"end":567},"obj":"Species"},{"id":"373","span":{"begin":734,"end":753},"obj":"Species"},{"id":"374","span":{"begin":934,"end":956},"obj":"Species"},{"id":"375","span":{"begin":804,"end":813},"obj":"Species"},{"id":"376","span":{"begin":196,"end":202},"obj":"Species"},{"id":"377","span":{"begin":4,"end":18},"obj":"Chemical"},{"id":"378","span":{"begin":278,"end":297},"obj":"Chemical"},{"id":"379","span":{"begin":317,"end":332},"obj":"Chemical"},{"id":"380","span":{"begin":121,"end":133},"obj":"Disease"},{"id":"381","span":{"begin":222,"end":260},"obj":"Disease"}],"attributes":[{"id":"A371","pred":"tao:has_database_id","subj":"371","obj":"Tax:11060"},{"id":"A372","pred":"tao:has_database_id","subj":"372","obj":"Tax:1477686"},{"id":"A373","pred":"tao:has_database_id","subj":"373","obj":"Tax:927723"},{"id":"A374","pred":"tao:has_database_id","subj":"374","obj":"Tax:1333989"},{"id":"A375","pred":"tao:has_database_id","subj":"375","obj":"Tax:1903211"},{"id":"A376","pred":"tao:has_database_id","subj":"376","obj":"Tax:11060"},{"id":"A377","pred":"tao:has_database_id","subj":"377","obj":"MESH:D009822"},{"id":"A378","pred":"tao:has_database_id","subj":"378","obj":"MESH:C515179"},{"id":"A379","pred":"tao:has_database_id","subj":"379","obj":"MESH:C024714"},{"id":"A380","pred":"tao:has_database_id","subj":"380","obj":"MESH:D064420"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T64","span":{"begin":175,"end":181},"obj":"Disease"}],"attributes":[{"id":"A64","pred":"mondo_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/MONDO_0005502"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T79","span":{"begin":158,"end":166},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T80","span":{"begin":182,"end":187},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T81","span":{"begin":536,"end":544},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T107","span":{"begin":4,"end":18},"obj":"Chemical"},{"id":"T108","span":{"begin":278,"end":297},"obj":"Chemical"},{"id":"T109","span":{"begin":278,"end":291},"obj":"Chemical"},{"id":"T110","span":{"begin":292,"end":297},"obj":"Chemical"},{"id":"T112","span":{"begin":319,"end":332},"obj":"Chemical"},{"id":"T113","span":{"begin":503,"end":515},"obj":"Chemical"},{"id":"T114","span":{"begin":589,"end":597},"obj":"Chemical"},{"id":"T115","span":{"begin":607,"end":612},"obj":"Chemical"},{"id":"T117","span":{"begin":626,"end":634},"obj":"Chemical"},{"id":"T118","span":{"begin":716,"end":730},"obj":"Chemical"},{"id":"T119","span":{"begin":763,"end":770},"obj":"Chemical"},{"id":"T120","span":{"begin":814,"end":821},"obj":"Chemical"},{"id":"T122","span":{"begin":868,"end":874},"obj":"Chemical"},{"id":"T123","span":{"begin":884,"end":895},"obj":"Chemical"},{"id":"T124","span":{"begin":909,"end":921},"obj":"Chemical"},{"id":"T125","span":{"begin":909,"end":919},"obj":"Chemical"},{"id":"T126","span":{"begin":976,"end":982},"obj":"Chemical"},{"id":"T127","span":{"begin":992,"end":1003},"obj":"Chemical"},{"id":"T128","span":{"begin":1017,"end":1029},"obj":"Chemical"},{"id":"T129","span":{"begin":1017,"end":1027},"obj":"Chemical"}],"attributes":[{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_67818"},{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_10357"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A111","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_10357"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_35187"},{"id":"A114","pred":"chebi_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/CHEBI_15384"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_16980"},{"id":"A116","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_29020"},{"id":"A117","pred":"chebi_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/CHEBI_16980"},{"id":"A118","pred":"chebi_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A119","pred":"chebi_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/CHEBI_36773"},{"id":"A120","pred":"chebi_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/CHEBI_16236"},{"id":"A121","pred":"chebi_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/CHEBI_30879"},{"id":"A122","pred":"chebi_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/CHEBI_17187"},{"id":"A123","pred":"chebi_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/CHEBI_132824"},{"id":"A124","pred":"chebi_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/CHEBI_49045"},{"id":"A125","pred":"chebi_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/CHEBI_36743"},{"id":"A126","pred":"chebi_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/CHEBI_17187"},{"id":"A127","pred":"chebi_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/CHEBI_132824"},{"id":"A128","pred":"chebi_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/CHEBI_49045"},{"id":"A129","pred":"chebi_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/CHEBI_36743"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}

{"project":"LitCovid-sentences","denotations":[{"id":"T57","span":{"begin":0,"end":209},"obj":"Sentence"},{"id":"T58","span":{"begin":210,"end":371},"obj":"Sentence"},{"id":"T59","span":{"begin":372,"end":460},"obj":"Sentence"},{"id":"T60","span":{"begin":461,"end":698},"obj":"Sentence"},{"id":"T61","span":{"begin":699,"end":1083},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}

{"project":"2_test","denotations":[{"id":"32408699-16130522-52981855","span":{"begin":205,"end":207},"obj":"16130522"},{"id":"T58997","span":{"begin":205,"end":207},"obj":"16130522"}],"text":"The essential oils of seven aromatic plants from Córdoba, San Luis, and San Juan provinces (Argentina) were screened for cytotoxicity and in vitro inhibitory activity against dengue virus type 2 (DENV−2) [38]. The oils of Jungia polita and Buddleja cordobensis were composed of caryophyllene oxide (9.18%, 32.1%) and β-caryophyllene (8.13%, 16.5%) as the major compounds. However, these oils displayed different IC50 values (86.4 and 39.8 μg/mL, respectively). The other samples were composed mostly of monoterpenes and displayed lower activity, except Pectis odorata oil, which presented limonene (50.2%), neral (27.2%), and geranial (23.6%) as the major compounds and an IC50 value of 39.6 μg/mL. In addition, the essential oils of Artemisia mendozana, rich in camphor (22.4%), artemisole (11.7%), and artemisia alcohol (10.8%); Gailardia megapotamica composed of β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%); and Heterothalamus alienus characterized by β-pinene (35.5%), spathulenol (10.7%), and germacrene D (6.8%), showed an average IC50 value of 130.63 μg/mL."}