PMC:7279430 / 19047-19636 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7279430","sourcedb":"PMC","sourceid":"7279430","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7279430","text":"The docking results of the essential oil components with the six randomly selected proteins indicate the best docking ligands to SARS-CoV-2 targets (i.e., (E,E)-α-farnesene, (E)-β-farnesene, and (E,E)-farnesol) have better docking energies with other proteins. These three sesquiterpenes have docking energies of −129.8, −122.7, and −133.0 kJ/mol with TcAChE, respectively, and −131.8, −131.8, and −135.6 kJ/mol, respectively, with BaNadD. Indeed, most of the essential oil ligands have better docking properties with one or more of the random proteins compared to the SARS-CoV-2 proteins.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T43","span":{"begin":83,"end":91},"obj":"Body_part"},{"id":"T44","span":{"begin":251,"end":259},"obj":"Body_part"},{"id":"T45","span":{"begin":544,"end":552},"obj":"Body_part"},{"id":"T46","span":{"begin":580,"end":588},"obj":"Body_part"}],"attributes":[{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"800","span":{"begin":129,"end":139},"obj":"Species"},{"id":"801","span":{"begin":158,"end":162},"obj":"Species"},{"id":"802","span":{"begin":569,"end":579},"obj":"Species"},{"id":"803","span":{"begin":27,"end":40},"obj":"Chemical"},{"id":"804","span":{"begin":174,"end":189},"obj":"Chemical"},{"id":"805","span":{"begin":195,"end":209},"obj":"Chemical"},{"id":"806","span":{"begin":273,"end":287},"obj":"Chemical"},{"id":"807","span":{"begin":460,"end":473},"obj":"Chemical"}],"attributes":[{"id":"A800","pred":"tao:has_database_id","subj":"800","obj":"Tax:2697049"},{"id":"A801","pred":"tao:has_database_id","subj":"801","obj":"Tax:114629"},{"id":"A802","pred":"tao:has_database_id","subj":"802","obj":"Tax:2697049"},{"id":"A803","pred":"tao:has_database_id","subj":"803","obj":"MESH:D009822"},{"id":"A806","pred":"tao:has_database_id","subj":"806","obj":"MESH:D012717"},{"id":"A807","pred":"tao:has_database_id","subj":"807","obj":"MESH:D009822"},{"subj":"800","pred":"source","obj":"LitCovid-PubTator"},{"subj":"801","pred":"source","obj":"LitCovid-PubTator"},{"subj":"802","pred":"source","obj":"LitCovid-PubTator"},{"subj":"803","pred":"source","obj":"LitCovid-PubTator"},{"subj":"804","pred":"source","obj":"LitCovid-PubTator"},{"subj":"805","pred":"source","obj":"LitCovid-PubTator"},{"subj":"806","pred":"source","obj":"LitCovid-PubTator"},{"subj":"807","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T114","span":{"begin":129,"end":137},"obj":"Disease"},{"id":"T115","span":{"begin":569,"end":577},"obj":"Disease"}],"attributes":[{"id":"A114","pred":"mondo_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A115","pred":"mondo_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T296","span":{"begin":27,"end":51},"obj":"Chemical"},{"id":"T297","span":{"begin":27,"end":40},"obj":"Chemical"},{"id":"T298","span":{"begin":83,"end":91},"obj":"Chemical"},{"id":"T299","span":{"begin":118,"end":125},"obj":"Chemical"},{"id":"T300","span":{"begin":163,"end":172},"obj":"Chemical"},{"id":"T301","span":{"begin":180,"end":189},"obj":"Chemical"},{"id":"T302","span":{"begin":195,"end":209},"obj":"Chemical"},{"id":"T303","span":{"begin":201,"end":209},"obj":"Chemical"},{"id":"T304","span":{"begin":251,"end":259},"obj":"Chemical"},{"id":"T305","span":{"begin":273,"end":287},"obj":"Chemical"},{"id":"T306","span":{"begin":460,"end":473},"obj":"Chemical"},{"id":"T307","span":{"begin":474,"end":481},"obj":"Chemical"},{"id":"T308","span":{"begin":544,"end":552},"obj":"Chemical"},{"id":"T309","span":{"begin":580,"end":588},"obj":"Chemical"}],"attributes":[{"id":"A296","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_27311"},{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_39237"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_39237"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_16619"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_28600"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_35189"},{"id":"A306","pred":"chebi_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/CHEBI_83630"},{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T296","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T297","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T298","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T299","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T300","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T301","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T302","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T303","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T304","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T305","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T306","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T307","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T308","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T309","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T127","span":{"begin":0,"end":260},"obj":"Sentence"},{"id":"T128","span":{"begin":261,"end":439},"obj":"Sentence"},{"id":"T129","span":{"begin":440,"end":589},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T127","pred":"source","obj":"LitCovid-sentences"},{"subj":"T128","pred":"source","obj":"LitCovid-sentences"},{"subj":"T129","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93a0","default":true},{"id":"LitCovid-PubTator","color":"#93baec"},{"id":"LitCovid-PD-MONDO","color":"#d4ec93"},{"id":"LitCovid-PD-CHEBI","color":"#e993ec"},{"id":"LitCovid-sentences","color":"#93eccf"}]}]}}