PMC:7278709 / 68602-73595
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T121 | 110-121 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T122 | 123-134 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T123 | 1868-1879 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T124 | 1883-1894 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T125 | 2150-2161 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T126 | 2170-2181 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T127 | 2357-2368 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T128 | 3420-3444 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetyl neuraminic acid |
| T129 | 3420-3444 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetyl neuraminic acid |
| T130 | 3766-3790 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetyl neuraminic acid |
| T131 | 3766-3790 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetyl neuraminic acid |
| T132 | 3830-3854 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetyl neuraminic acid |
| T133 | 3830-3854 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetyl neuraminic acid |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1134 | 110-121 | CHEBI:26667;CHEBI:26667 | denotes | sialic acid |
| T1135 | 135-141 | CHEBI:17089;CHEBI:17089 | denotes | glycan |
| T1136 | 1186-1214 | CHEBI:17089;CHEBI:17089 | denotes | gatively charged that are in |
| T1137 | 1272-1284 | SP_7 | denotes | sual central |
| T1138 | 1818-1835 | NCBITaxon:10239 | denotes | valued parameters |
| T1139 | 1931-1977 | NCBITaxon:1 | denotes | three charged amino acid residue can sometimes |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T461 | 28-36 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T462 | 49-57 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T463 | 323-331 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T464 | 810-820 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T465 | 943-950 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T466 | 1019-1029 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T467 | 1136-1144 | Body_part | denotes | glycines | http://purl.org/sig/ont/fma/fma82753 |
| T468 | 1293-1303 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T469 | 1410-1417 | Body_part | denotes | glycine | http://purl.org/sig/ont/fma/fma82753 |
| T470 | 1460-1470 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T471 | 1500-1510 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T472 | 1626-1637 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T473 | 1686-1695 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
| T474 | 1783-1791 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T475 | 1797-1803 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T476 | 1945-1955 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T477 | 2211-2222 | Body_part | denotes | head region | http://purl.org/sig/ont/fma/fma24218 |
| T478 | 2292-2300 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T479 | 2320-2326 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T480 | 2672-2681 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
| T481 | 2726-2737 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T482 | 2992-3002 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T483 | 3059-3069 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T484 | 3114-3122 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T485 | 3291-3301 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T486 | 3316-3322 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T487 | 3420-3444 | Body_part | denotes | N-acetyl neuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T488 | 3485-3495 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T489 | 3569-3582 | Body_part | denotes | phenylalanine | http://purl.org/sig/ont/fma/fma82754 |
| T490 | 3610-3616 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T491 | 3766-3790 | Body_part | denotes | N-acetyl neuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T492 | 3830-3854 | Body_part | denotes | N-acetyl neuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
| T493 | 3992-4000 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T494 | 4009-4015 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T495 | 4224-4230 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T496 | 4234-4242 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T497 | 4254-4260 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T498 | 4468-4478 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T499 | 4750-4760 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T500 | 4800-4806 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T501 | 4815-4823 | Body_part | denotes | arginine | http://purl.org/sig/ont/fma/fma82763 |
| T502 | 4844-4854 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
| T503 | 4922-4932 | Body_part | denotes | tryptophan | http://purl.org/sig/ont/fma/fma82767 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T28 | 2211-2215 | Body_part | denotes | head | http://purl.obolibrary.org/obo/UBERON_0000033 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T160 | 379-388 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T161 | 462-471 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T162 | 2230-2247 | Disease | denotes | Newcastle disease | http://purl.obolibrary.org/obo/MONDO_0005875 |
| T163 | 4435-4438 | Disease | denotes | SWS | http://purl.obolibrary.org/obo/MONDO_0008501 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T615 | 26-27 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T616 | 46-47 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T617 | 64-70 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T618 | 389-390 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T619 | 472-473 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T620 | 563-568 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T621 | 726-727 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T622 | 772-773 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T623 | 908-909 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T624 | 955-956 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T625 | 1017-1018 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T626 | 1039-1040 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T627 | 1121-1122 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T628 | 1316-1317 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T629 | 1480-1481 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T630 | 1491-1494 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T631 | 1548-1549 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T632 | 1945-1963 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residue |
| T633 | 1945-1963 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residue |
| T634 | 2211-2222 | http://purl.obolibrary.org/obo/UBERON_0001444 | denotes | head region |
| T635 | 2248-2253 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T636 | 2269-2270 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T637 | 2318-2319 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T638 | 2377-2378 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T639 | 2468-2469 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T640 | 2544-2545 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T641 | 2709-2710 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T642 | 3074-3077 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T643 | 3083-3084 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T644 | 3107-3110 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T645 | 3214-3215 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T646 | 3289-3290 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T647 | 3479-3482 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T648 | 3529-3530 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T649 | 3567-3568 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T650 | 3601-3602 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T651 | 4165-4166 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T652 | 4252-4253 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T653 | 4486-4487 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T654 | 4552-4553 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T655 | 4601-4602 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T656 | 4969-4970 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T57475 | 20-25 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T19333 | 28-36 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T77707 | 40-45 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T98630 | 49-57 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T51262 | 110-121 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T67469 | 117-121 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T6307 | 123-134 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T7610 | 130-134 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T39926 | 323-331 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T40612 | 810-820 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T27079 | 943-950 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T16665 | 1019-1029 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T26940 | 1160-1169 | Chemical | denotes | glutamate | http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987 |
| T72451 | 1293-1303 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T25293 | 1410-1417 | Chemical | denotes | glycine | http://purl.obolibrary.org/obo/CHEBI_15428|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_57305 |
| T42373 | 1460-1470 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T9870 | 1500-1510 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T84921 | 1550-1559 | Chemical | denotes | glutamate | http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987 |
| T99542 | 1626-1637 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T71728 | 1626-1631 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T53536 | 1632-1637 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T15370 | 1668-1677 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
| T48481 | 1686-1695 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
| T6928 | 1769-1778 | Chemical | denotes | glutamate | http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987 |
| T42023 | 1783-1791 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T71010 | 1797-1803 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T42627 | 1868-1879 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T51651 | 1875-1879 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T54085 | 1883-1894 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T25961 | 1890-1894 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T73529 | 1945-1963 | Chemical | denotes | amino acid residue | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T36422 | 1945-1955 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T37621 | 1945-1950 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T87115 | 1951-1955 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T80254 | 1998-2002 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T29550 | 2150-2161 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T4874 | 2157-2161 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T65048 | 2170-2181 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T41625 | 2177-2181 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T63405 | 2271-2280 | Chemical | denotes | glutamate | http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987 |
| T12923 | 2292-2300 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T64175 | 2320-2326 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T15133 | 2357-2368 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T23762 | 2364-2368 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T68491 | 2369-2375 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T2222 | 2654-2663 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
| T92241 | 2672-2681 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
| T57465 | 2726-2737 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T78483 | 2726-2731 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T42476 | 2732-2737 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T58166 | 2992-3002 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T94410 | 3059-3069 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T53238 | 3114-3122 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T82548 | 3291-3301 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T16618 | 3316-3322 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T18754 | 3420-3444 | Chemical | denotes | N-acetyl neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T82977 | 3422-3428 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T72347 | 3429-3444 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T46656 | 3440-3444 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T11482 | 3485-3495 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T58406 | 3569-3582 | Chemical | denotes | phenylalanine | http://purl.obolibrary.org/obo/CHEBI_28044|http://purl.obolibrary.org/obo/CHEBI_58095 |
| T42082 | 3610-3616 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T16584 | 3640-3642 | Chemical | denotes | FN | http://purl.obolibrary.org/obo/CHEBI_73633 |
| T15765 | 3713-3732 | Chemical | denotes | phosphoenolpyruvate | http://purl.obolibrary.org/obo/CHEBI_18021|http://purl.obolibrary.org/obo/CHEBI_58702 |
| T43419 | 3737-3756 | Chemical | denotes | N-acetylmannosamine | http://purl.obolibrary.org/obo/CHEBI_62164|http://purl.obolibrary.org/obo/CHEBI_63153 |
| T31369 | 3766-3790 | Chemical | denotes | N-acetyl neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T28558 | 3768-3774 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T75935 | 3775-3790 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T87120 | 3786-3790 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T53582 | 3830-3854 | Chemical | denotes | N-acetyl neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
| T7904 | 3832-3838 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
| T45052 | 3839-3854 | Chemical | denotes | neuraminic acid | http://purl.obolibrary.org/obo/CHEBI_49018 |
| T94652 | 3850-3854 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T29372 | 3977-3986 | Chemical | denotes | glutamate | http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987 |
| T74769 | 3992-4000 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T29287 | 4009-4015 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T18320 | 4224-4230 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T4873 | 4234-4242 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T55661 | 4254-4260 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T47210 | 4468-4478 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T47840 | 4681-4683 | Chemical | denotes | ox | http://purl.obolibrary.org/obo/CHEBI_30623 |
| T78935 | 4750-4760 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T15742 | 4800-4806 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T73067 | 4815-4823 | Chemical | denotes | arginine | http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696 |
| T98372 | 4844-4854 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
| T5511 | 4922-4932 | Chemical | denotes | tryptophan | http://purl.obolibrary.org/obo/CHEBI_16828|http://purl.obolibrary.org/obo/CHEBI_27897|http://purl.obolibrary.org/obo/CHEBI_57719|http://purl.obolibrary.org/obo/CHEBI_57912 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T401 | 0-36 | Sentence | denotes | 4.5 Predictions of group a proteins |
| T402 | 37-189 | Sentence | denotes | In group A, proteins being tested are believed to be able to accommodate sialic acid, sialic acid glycan, and related compounds by non-covalent binding. |
| T403 | 190-317 | Sentence | denotes | Predicted correctly, these would represent the true positives, but predicted incorrectly, they would represent false negatives. |
| T404 | 318-413 | Sentence | denotes | Such proteins include various hemagglutinins such as that of influenza A at GenBank CAA24291.1. |
| T405 | 414-543 | Sentence | denotes | It also included various neuraminidases such as influenza A in GenBank entry AAL60438.1 with the following predicted subsequence. |
| T406 | 544-610 | Sentence | denotes | Another example is human neuraminidase (GenBank entry CAB41449.1). |
| T407 | 611-859 | Sentence | denotes | Generally arbitrarily selected neuraminidases and hemagglutinins are true positives but the above kind of pattern, a segment of approximately 9–23 residues with a score exceeding 100 and centered on tryptophan with the peak score, is not universal. |
| T408 | 860-904 | Sentence | denotes | Sometimes it is another hydrophobic residue. |
| T409 | 905-1149 | Sentence | denotes | In a “haemaglutinin repeat-containing protein” of a yet to be fully classified micororganism Candidatus Kentron a tryptophan (W) with a score of 118 is slightly displaced from the central peak of 119 associated with a run of three glycines (G). |
| T410 | 1150-1304 | Sentence | denotes | It is two glutamate residues (E), negatively charged that are in the vicinity in the sequence that appear to perturb the usual central role of tryptophan. |
| T411 | 1305-1495 | Sentence | denotes | Similarly, a rat neuraminidase is of some interest in that the predicted sequence SLDHGHTW surrounds the glycine (G) with peak score 106 and terminates at tryptophan (W) with a score of 102. |
| T412 | 1496-1564 | Sentence | denotes | The tryptophan is, however, immediately followed by a glutamate (E). |
| T413 | 1565-1618 | Sentence | denotes | The significance of the above comments is as follows. |
| T414 | 1619-1910 | Sentence | denotes | Of the amino acids with charged sidechains, only aspartate (D) and histidine (H) appear to favor such binding in the present author's analysis, while glutamate (E) arginine (R), lysine (K) have zero valued parameters and so are contraindications of sialic acid or sialic acid glycan binding. |
| T415 | 1911-2070 | Sentence | denotes | However, the latter three charged amino acid residue can sometimes be found in scialic acid binding sites and in sites predicted as such by the present method. |
| T416 | 2071-2162 | Sentence | denotes | Indeed, they are often dominant features of residues directly interacting with sialic acid. |
| T417 | 2163-2376 | Sentence | denotes | In the sialic acid binding site of the globular head region of the Newcastle disease virus haemagluttinin a glutamate (E), three arginine residues (R) and a lysine (K) are intimate contact with sialic acid ligand. |
| T418 | 2377-2499 | Sentence | denotes | A difference is that these residues make intimate contact in space and are not together in a one or very few subsequences. |
| T419 | 2500-2561 | Sentence | denotes | That is, they do not necessarily constitute a sequence motif. |
| T420 | 2562-2804 | Sentence | denotes | The actual extent of any counter-predictive impact of the above charged residues other than aspartate (D) and histidine (H), when they together in a subsequence of amino acids examined by the present algorithm, can be seen in false negatives. |
| T421 | 2805-3162 | Sentence | denotes | The neuraminidase of the plant Striga asiatica (Asian witchweed), was one of the false negatives: the analogous region to many of the above, at least in the sense of surrounding the only tryptophan (W) and with the peak value, is EGAVDRWRGEANF where the tryptophan (W) has only a peak value of 88, and has an arginine (R), positively charged, on both sides. |
| T422 | 3163-3389 | Sentence | denotes | The other false negative in the original study was a bacterial (Chryseobacterium) haemagluttinin with the peak value of 93 at a tryptophan, but with two lysine residues (K), also positively charged sidechains, in the vicinity. |
| T423 | 3390-3670 | Sentence | denotes | Later studies also noted that N-acetyl neuraminic acid synthetase NeuB of E. coli, which has 4 tryptophan residues (W), but did not exceed a score of 95 which was the score for a phenylalanine (F), and there is a single lysine near the peak value at FN of 95 in subsequence FNLYK. |
| T424 | 3671-3902 | Sentence | denotes | This enzyme catalyzes the condensation of phosphoenolpyruvate and N-acetylmannosamine) to form N-acetyl neuraminic acid, so it is possible that the binding to N-acetyl neuraminic acid is much weaker in order to release the product. |
| T425 | 3903-4174 | Sentence | denotes | Nonetheless, closer examination shows that the contraindicative effect of glutamate (E), arginine (R) and lysine (K is not strong in the context of the algorithm and typical subsequences, so failure to predict is in practice more an effect of the subsequence as a whole). |
| T426 | 4175-4361 | Sentence | denotes | In the above and similar cases, substituting the lysine or arginine by, say, a serine (S) in “computer experiments” does not typically increase the score of any residue to more than 100. |
| T427 | 4362-4537 | Sentence | denotes | For example, in the case of the witchweed neuraminidase, changing RWR to SWS raised the peak value at the tryptophan to 99, a significant increase but still not exceeding 100. |
| T428 | 4538-4600 | Sentence | denotes | In some cases a value exceeding 100 can of course be attained. |
| T429 | 4601-4784 | Sentence | denotes | A false negative also found in later studies investigating these issues was the ox neuraminidase, with the subsequence DDHGVSWRYGGGVS containing the tryptophan (W) with peak value 96. |
| T430 | 4785-4993 | Sentence | denotes | Changing to an serine (S) the arginine (R) adjacent to the tryptophan (W) did have an effect, albeit that the only change was having the tryptophan as the only residue predicted, with a marginal score of 101. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1235 | 379-388 | Species | denotes | influenza | Tax:11552 |
| 1236 | 110-121 | Chemical | denotes | sialic acid | MESH:D019158 |
| 1237 | 123-141 | Chemical | denotes | sialic acid glycan | |
| 1239 | 462-471 | Species | denotes | influenza | Tax:11552 |
| 1242 | 569-582 | Gene | denotes | neuraminidase | Gene:4758 |
| 1243 | 563-568 | Species | denotes | human | Tax:9606 |
| 1257 | 1322-1335 | Gene | denotes | neuraminidase | Gene:4758 |
| 1258 | 1561-1562 | Gene | denotes | E | Gene:43740570 |
| 1259 | 1180-1181 | Gene | denotes | E | Gene:43740570 |
| 1260 | 1318-1321 | Species | denotes | rat | Tax:10116 |
| 1261 | 810-820 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1262 | 1019-1029 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1263 | 1136-1144 | Chemical | denotes | glycines | MESH:D005998 |
| 1264 | 1160-1169 | Chemical | denotes | glutamate | MESH:D018698 |
| 1265 | 1293-1303 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1266 | 1410-1417 | Chemical | denotes | glycine | MESH:D005998 |
| 1267 | 1460-1470 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1268 | 1500-1510 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1269 | 1550-1559 | Chemical | denotes | glutamate | MESH:D018698 |
| 1285 | 2230-2253 | Species | denotes | Newcastle disease virus | Tax:11176 |
| 1286 | 1668-1677 | Chemical | denotes | aspartate | MESH:D001224 |
| 1287 | 1686-1695 | Chemical | denotes | histidine | MESH:D006639 |
| 1288 | 1769-1778 | Chemical | denotes | glutamate | MESH:D018698 |
| 1289 | 1783-1791 | Chemical | denotes | arginine | MESH:D001120 |
| 1290 | 1797-1803 | Chemical | denotes | lysine | MESH:D008239 |
| 1291 | 1868-1879 | Chemical | denotes | sialic acid | MESH:D019158 |
| 1292 | 1883-1901 | Chemical | denotes | sialic acid glycan | |
| 1293 | 1990-2002 | Chemical | denotes | scialic acid | |
| 1294 | 2150-2161 | Chemical | denotes | sialic acid | MESH:D019158 |
| 1295 | 2170-2181 | Chemical | denotes | sialic acid | MESH:D019158 |
| 1296 | 2271-2280 | Chemical | denotes | glutamate | MESH:D018698 |
| 1297 | 2292-2300 | Chemical | denotes | arginine | MESH:D001120 |
| 1298 | 2320-2326 | Chemical | denotes | lysine | MESH:D008239 |
| 1299 | 2357-2368 | Chemical | denotes | sialic acid | MESH:D019158 |
| 1315 | 2809-2822 | Gene | denotes | neuraminidase | Gene:4758 |
| 1316 | 2836-2851 | Species | denotes | Striga asiatica | Tax:4170 |
| 1317 | 2859-2868 | Species | denotes | witchweed | Tax:4170 |
| 1318 | 3464-3471 | Species | denotes | E. coli | Tax:562 |
| 1319 | 2654-2663 | Chemical | denotes | aspartate | MESH:D001224 |
| 1320 | 2672-2681 | Chemical | denotes | histidine | MESH:D006639 |
| 1321 | 2992-3002 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1322 | 3059-3069 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1323 | 3114-3122 | Chemical | denotes | arginine | MESH:D001120 |
| 1324 | 3291-3301 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1325 | 3316-3322 | Chemical | denotes | lysine | MESH:D008239 |
| 1326 | 3485-3495 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1327 | 3569-3582 | Chemical | denotes | phenylalanine | MESH:D010649 |
| 1328 | 3610-3616 | Chemical | denotes | lysine | MESH:D008239 |
| 1329 | 3713-3732 | Chemical | denotes | phosphoenolpyruvate | MESH:D010728 |
| 1348 | 4404-4417 | Gene | denotes | neuraminidase | Gene:4758 |
| 1349 | 4684-4697 | Gene | denotes | neuraminidase | Gene:4758 |
| 1350 | 3988-3989 | Gene | denotes | E | Gene:43740570 |
| 1351 | 4808-4809 | Gene | denotes | S | Gene:43740568 |
| 1352 | 4262-4263 | Gene | denotes | S | Gene:43740568 |
| 1353 | 4394-4403 | Species | denotes | witchweed | Tax:4170 |
| 1354 | 3977-3986 | Chemical | denotes | glutamate | MESH:D018698 |
| 1355 | 3992-4000 | Chemical | denotes | arginine | MESH:D001120 |
| 1356 | 4009-4015 | Chemical | denotes | lysine | MESH:D008239 |
| 1357 | 4224-4230 | Chemical | denotes | lysine | MESH:D008239 |
| 1358 | 4234-4242 | Chemical | denotes | arginine | MESH:D001120 |
| 1359 | 4254-4260 | Chemical | denotes | serine | MESH:D012694 |
| 1360 | 4468-4478 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1361 | 4750-4760 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1362 | 4800-4806 | Chemical | denotes | serine | MESH:D012694 |
| 1363 | 4815-4823 | Chemical | denotes | arginine | MESH:D001120 |
| 1364 | 4844-4854 | Chemical | denotes | tryptophan | MESH:D014364 |
| 1365 | 4922-4932 | Chemical | denotes | tryptophan | MESH:D014364 |