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PMC:7278327 / 1562-10442 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T12 1064-1071 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T13 1260-1264 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T14 1299-1317 Body_part denotes alveolar epithelia http://purl.org/sig/ont/fma/fma63915
T15 1308-1317 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T16 1322-1331 Body_part denotes capillary http://purl.org/sig/ont/fma/fma63194
T17 1332-1337 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T18 1736-1755 Body_part denotes corticospinal tract http://purl.org/sig/ont/fma/fma265580
T19 1859-1863 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T20 1994-1997 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T21 2042-2074 Body_part denotes nicotinic acetylcholine receptor http://purl.org/sig/ont/fma/fma61796
T22 2306-2309 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T23 2390-2393 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T24 2406-2421 Body_part denotes olfactory nerve http://purl.org/sig/ont/fma/fma46787
T25 2444-2451 Body_part denotes neurons http://purl.org/sig/ont/fma/fma54527
T26 2536-2556 Body_part denotes olfactory epithelium http://purl.org/sig/ont/fma/fma64803
T27 2546-2556 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T28 2705-2712 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T29 2787-2790 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T30 3458-3461 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T31 3740-3743 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T32 3969-3974 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T33 3975-3980 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T34 4060-4063 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T35 4251-4259 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T36 4303-4306 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T37 4513-4516 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T38 4666-4686 Body_part denotes olfactory epithelium http://purl.org/sig/ont/fma/fma64803
T39 4676-4686 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T40 4698-4710 Body_part denotes nasal cavity http://purl.org/sig/ont/fma/fma54378
T41 4833-4850 Body_part denotes non-neuronal cell http://purl.org/sig/ont/fma/fma54536
T42 4846-4850 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T43 4937-4940 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T44 4972-4975 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T45 5119-5139 Body_part denotes olfactory epithelium http://purl.org/sig/ont/fma/fma64803
T46 5129-5139 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T47 5256-5259 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T48 5363-5379 Body_part denotes trigeminal nerve http://purl.org/sig/ont/fma/fma50866
T49 5401-5421 Body_part denotes olfactory epithelium http://purl.org/sig/ont/fma/fma64803
T50 5411-5421 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T51 5444-5451 Body_part denotes neurons http://purl.org/sig/ont/fma/fma54527
T52 5541-5551 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T53 5574-5586 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T54 5588-5591 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T55 5660-5663 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T56 5771-5774 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T57 6019-6026 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T58 6064-6075 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T59 6321-6328 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T60 6333-6336 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T61 6421-6424 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T62 6641-6649 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T63 6703-6710 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T64 6720-6732 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T65 6947-6955 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T66 6987-6994 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T67 7325-7328 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T68 7702-7706 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T69 8402-8409 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T70 8462-8469 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T71 8631-8641 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T72 8819-8831 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T73 8867-8874 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1260-1264 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 1299-1317 Body_part denotes alveolar epithelia http://purl.obolibrary.org/obo/UBERON_0004821
T3 1308-1317 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T4 1322-1331 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982
T5 1736-1755 Body_part denotes corticospinal tract http://purl.obolibrary.org/obo/UBERON_0002707
T6 2406-2421 Body_part denotes olfactory nerve http://purl.obolibrary.org/obo/UBERON_0001579
T7 2416-2421 Body_part denotes nerve http://purl.obolibrary.org/obo/UBERON_0001021
T8 2536-2556 Body_part denotes olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0001997
T9 2546-2556 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T10 3969-3988 Body_part denotes blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T11 3969-3974 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T12 3975-3980 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T13 4666-4686 Body_part denotes olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0001997
T14 4676-4686 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T15 4698-4710 Body_part denotes nasal cavity http://purl.obolibrary.org/obo/UBERON_0001707
T16 4914-4931 Body_part denotes olfactory pathway http://purl.obolibrary.org/obo/UBERON_0013201
T17 5119-5139 Body_part denotes olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0001997
T18 5129-5139 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T19 5363-5379 Body_part denotes trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0001645
T20 5374-5379 Body_part denotes nerve http://purl.obolibrary.org/obo/UBERON_0001021
T21 5401-5421 Body_part denotes olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0001997
T22 5411-5421 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T23 5605-5616 Body_part denotes snake venom http://purl.obolibrary.org/obo/UBERON_0013076
T24 5611-5616 Body_part denotes venom http://purl.obolibrary.org/obo/UBERON_0007113
T25 5877-5888 Body_part denotes snake venom http://purl.obolibrary.org/obo/UBERON_0013076
T26 5883-5888 Body_part denotes venom http://purl.obolibrary.org/obo/UBERON_0007113

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
62 38-51 Species denotes β-coronavirus Tax:694002
63 53-100 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
64 102-112 Species denotes SARS-CoV-2 Tax:2697049
65 448-459 Species denotes coronavirus Tax:11118
66 152-176 Disease denotes coronavirus disease 2019 MESH:C000657245
67 178-186 Disease denotes COVID-19 MESH:C000657245
68 265-273 Disease denotes COVID-19 MESH:C000657245
69 291-297 Disease denotes deaths MESH:D003643
70 305-313 Disease denotes COVID-19 MESH:C000657245
71 342-350 Disease denotes COVID-19 MESH:C000657245
97 1160-1191 Gene denotes angiotensin-converting enzyme-2 Gene:59272
98 1193-1197 Gene denotes ACE2 Gene:59272
99 1291-1295 Gene denotes ACE2 Gene:59272
100 1058-1063 Gene denotes spike Gene:43740568
101 722-732 Species denotes SARS-CoV-2 Tax:2697049
102 792-837 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
103 839-847 Species denotes SARS-CoV Tax:694009
104 887-895 Species denotes MERS-CoV Tax:1335626
105 939-947 Species denotes SARS-CoV Tax:694009
106 952-962 Species denotes SARS-CoV-2 Tax:2697049
107 1604-1612 Species denotes patients Tax:9606
108 674-682 Disease denotes COVID-19 MESH:C000657245
109 707-716 Disease denotes infection MESH:D007239
110 853-885 Disease denotes Middle East respiratory syndrome MESH:D018352
111 1356-1365 Disease denotes infection MESH:D007239
112 1421-1440 Disease denotes respiratory disease MESH:D012140
113 1502-1522 Disease denotes SARS-CoV-2 infection MESH:C000657245
114 1578-1597 Disease denotes respiratory disease MESH:D012140
115 1645-1651 Disease denotes nausea MESH:D009325
116 1653-1661 Disease denotes vomiting MESH:D014839
117 1663-1670 Disease denotes anosmia MESH:D000857
118 1687-1709 Disease denotes impaired consciousness MESH:D003244
119 1711-1720 Disease denotes agitation MESH:D011595
120 1767-1791 Disease denotes cerebrovascular diseases MESH:D002561
121 1803-1817 Disease denotes encephalopathy MESH:D001927
143 2076-2081 Gene denotes nAChR Gene:1137
144 2365-2370 Gene denotes nAChR Gene:1137
145 2633-2638 Gene denotes nAChR Gene:1137
146 2854-2859 Gene denotes nAChR Gene:1137
147 3090-3095 Gene denotes nAChR Gene:1137
148 3499-3504 Gene denotes nAChR Gene:1137
149 1947-1959 Species denotes rabies virus Tax:11292
150 2206-2216 Species denotes SARS-CoV-2 Tax:2697049
151 2354-2364 Species denotes SARS-CoV-2 Tax:2697049
152 2752-2762 Species denotes SARS-CoV-2 Tax:2697049
153 2843-2853 Species denotes SARS-CoV-2 Tax:2697049
154 3079-3089 Species denotes SARS-CoV-2 Tax:2697049
155 3235-3246 Species denotes coronavirus Tax:11118
156 3398-3408 Species denotes SARS-CoV-2 Tax:2697049
157 1961-1965 Species denotes RABV Tax:11292
158 3334-3338 Species denotes RABV Tax:11292
159 2052-2065 Chemical denotes acetylcholine MESH:D000109
160 1967-1977 Disease denotes infections MESH:D007239
161 2960-2968 Disease denotes COVID-19 MESH:C000657245
162 2969-2978 Disease denotes infection MESH:D007239
163 3124-3132 Disease denotes COVID-19 MESH:C000657245
168 3571-3576 Gene denotes nAChR Gene:1137
169 3519-3523 Gene denotes Case
170 3556-3566 Species denotes SARS-CoV-2 Tax:2697049
171 3603-3611 Disease denotes COVID-19 MESH:C000657245
183 3665-3670 Gene denotes nAChR Gene:1137
184 4271-4301 Species denotes human immunodeficiency virus 1 Tax:11676
185 4303-4308 Species denotes HIV-1 Tax:11676
186 4319-4327 Species denotes MERS-CoV Tax:1335626
187 4345-4362 Species denotes hepatitis C virus Tax:11103
188 3707-3711 Species denotes RABV Tax:11292
189 3919-3923 Species denotes RABV Tax:11292
190 4008-4012 Species denotes RABV Tax:11292
191 4129-4133 Species denotes RABV Tax:11292
192 4209-4213 Species denotes RABV Tax:11292
193 4364-4367 Species denotes HCV Tax:11103
207 4801-4805 Gene denotes ACE2 Gene:59272
208 4996-5001 Gene denotes nAChR Gene:1137
209 5293-5298 Gene denotes nAChR Gene:1137
210 4518-4526 Species denotes Patients Tax:9606
211 4985-4995 Species denotes SARS-CoV-2 Tax:2697049
212 5230-5234 Species denotes RABV Tax:11292
213 5288-5292 Species denotes RABV Tax:11292
214 4481-4501 Disease denotes SARS-CoV-2 infection MESH:C000657245
215 4532-4540 Disease denotes COVID-19 MESH:C000657245
216 4563-4592 Disease denotes sensory neurological symptoms MESH:D009422
217 4606-4613 Disease denotes anosmia MESH:D000857
218 4747-4767 Disease denotes SARS-CoV-2 infection MESH:C000657245
219 5235-5244 Disease denotes infection MESH:D007239
240 5594-5599 Gene denotes gp120 Gene:3700
241 5676-5681 Gene denotes gp120 Gene:3700
242 5970-5975 Gene denotes nAChR Gene:1137
243 6013-6018 Gene denotes spike Gene:43740568
244 6315-6320 Gene denotes spike Gene:43740568
245 6339-6344 Gene denotes gp120 Gene:3700
246 6697-6702 Gene denotes spike Gene:43740568
247 5588-5593 Species denotes HIV-1 Tax:11676
248 5660-5665 Species denotes HIV-1 Tax:11676
249 5757-5765 Species denotes patients Tax:9606
250 6002-6012 Species denotes SARS-CoV-2 Tax:2697049
251 6304-6314 Species denotes SARS-CoV-2 Tax:2697049
252 6333-6338 Species denotes HIV-1 Tax:11676
253 6686-6696 Species denotes SARS-CoV-2 Tax:2697049
254 5569-5573 Species denotes RABV Tax:11292
255 6599-6603 Species denotes RABV Tax:11292
256 6715-6719 Species denotes RABV Tax:11292
257 6271-6276 Gene denotes nAChR Gene:1137
258 5502-5507 Gene denotes nAChR Gene:1137
259 5771-5812 Disease denotes HIV-1-associated neurocognitive disorders MESH:D019965
289 6981-6986 Gene denotes spike Gene:43740568
290 7728-7733 Gene denotes nAChR Gene:1137
291 8706-8711 Gene denotes nAChR Gene:1137
292 8861-8866 Gene denotes spike Gene:43740568
293 8456-8461 Gene denotes spike Gene:43740568
294 6970-6980 Species denotes SARS-CoV-2 Tax:2697049
295 7303-7313 Species denotes SARS-CoV-2 Tax:2697049
296 7409-7414 Species denotes human Tax:9606
297 7514-7519 Species denotes human Tax:9606
298 7651-7661 Species denotes SARS-CoV-2 Tax:2697049
299 7687-7692 Species denotes human Tax:9606
300 7824-7829 Species denotes human Tax:9606
301 7926-7934 Species denotes SARS-CoV Tax:694009
302 7940-7970 Species denotes canine respiratory coronavirus Tax:215681
303 8018-8024 Species denotes canine Tax:9615
304 8137-8141 Species denotes dogs Tax:9615
305 8392-8401 Species denotes mammalian Tax:9606
306 8445-8455 Species denotes SARS-CoV-2 Tax:2697049
307 8850-8860 Species denotes SARS-CoV-2 Tax:2697049
308 6896-6900 Species denotes RABV Tax:11292
309 7465-7469 Species denotes RABV Tax:11292
310 7536-7540 Species denotes RABV Tax:11292
311 7972-7977 Species denotes CRCoV Tax:215681
312 8157-8162 Species denotes CRCoV Tax:215681
313 8222-8226 Species denotes RABV Tax:11292
314 8807-8811 Species denotes RABV Tax:11292
315 8300-8305 Gene denotes nAChR Gene:1137
316 7095-7103 Disease denotes COVID 19 MESH:C000657245
317 8036-8055 Disease denotes respiratory disease MESH:D012140

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T17 53-100 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T18 53-86 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T19 102-110 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 152-176 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T21 178-186 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 265-273 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 305-313 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 342-350 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 674-682 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 707-716 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T27 722-730 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 792-825 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T29 839-847 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 939-947 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 952-960 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T32 1350-1365 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T33 1356-1365 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T34 1421-1440 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T35 1502-1510 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 1513-1522 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T37 1578-1597 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T38 1663-1670 Disease denotes anosmia http://purl.obolibrary.org/obo/MONDO_0010528
T39 1767-1791 Disease denotes cerebrovascular diseases http://purl.obolibrary.org/obo/MONDO_0011057
T40 1803-1817 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T41 1947-1953 Disease denotes rabies http://purl.obolibrary.org/obo/MONDO_0019173
T42 1967-1977 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T43 2206-2214 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 2354-2362 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 2752-2760 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 2843-2851 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 2960-2968 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 2969-2978 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T49 3079-3087 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 3124-3132 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T51 3398-3406 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 3556-3564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T53 3603-3611 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 4277-4293 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T55 4345-4356 Disease denotes hepatitis C http://purl.obolibrary.org/obo/MONDO_0005231
T56 4345-4354 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T57 4481-4489 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 4492-4501 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T59 4532-4540 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T60 4606-4613 Disease denotes anosmia http://purl.obolibrary.org/obo/MONDO_0010528
T61 4747-4755 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 4758-4767 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T63 4985-4993 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 5235-5244 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 6002-6010 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 6304-6312 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 6686-6694 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 6970-6978 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 7095-7103 Disease denotes COVID 19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 7303-7311 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 7415-7421 Disease denotes rabies http://purl.obolibrary.org/obo/MONDO_0019173
T72 7651-7659 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 7915-7925 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T74 7926-7934 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 8025-8035 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T76 8036-8055 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T77 8445-8453 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 8850-8858 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T27 115-118 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T28 131-132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 517-525 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T30 1055-1057 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T31 1260-1264 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T32 1260-1264 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T33 1332-1337 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T34 1523-1526 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T35 1845-1846 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 1885-1888 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T37 1954-1959 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T38 1994-1997 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T39 1994-1997 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T40 2015-2020 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T41 2087-2090 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T42 2128-2129 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T43 2306-2309 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T44 2306-2309 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T45 2390-2393 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T46 2390-2393 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T47 2416-2421 http://purl.obolibrary.org/obo/UBERON_0001021 denotes nerve
T48 2546-2556 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T49 2604-2608 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T50 2787-2790 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T51 2787-2790 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T52 2801-2802 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 2884-2885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 3059-3060 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 3177-3179 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T56 3269-3270 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 3377-3378 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 3396-3397 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 3458-3461 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T60 3458-3461 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T61 3477-3478 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62 3528-3529 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 3682-3683 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 3740-3743 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T65 3740-3743 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T66 3969-3974 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T67 3969-3974 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T68 3975-3980 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T69 3975-3980 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T70 4060-4063 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T71 4060-4063 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T72 4134-4137 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T73 4271-4276 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T74 4294-4299 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T75 4357-4362 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T76 4411-4412 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77 4513-4516 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T78 4513-4516 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T79 4639-4642 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T80 4676-4686 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T81 4704-4710 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavity
T82 4820-4821 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83 4846-4856 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T84 4937-4940 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T85 4937-4940 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T86 4972-4975 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T87 4972-4975 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T88 5129-5139 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T89 5214-5215 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 5256-5259 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T91 5256-5259 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T92 5374-5379 http://purl.obolibrary.org/obo/UBERON_0001021 denotes nerve
T93 5411-5421 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T94 5463-5464 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 5490-5491 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 5629-5632 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T97 5683-5686 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T98 5859-5861 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T99 6060-6063 http://purl.obolibrary.org/obo/CLO_0053799 denotes 4-5
T100 6229-6231 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T101 6421-6424 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T102 6421-6424 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T103 6440-6442 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T104 6536-6543 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T105 6771-6774 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T106 6785-6786 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 6803-6804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 6872-6873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 7017-7018 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 7325-7328 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T111 7325-7328 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T112 7409-7414 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T113 7504-7510 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T114 7514-7519 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T115 7687-7692 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T116 7702-7712 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T117 7824-7829 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T118 7906-7907 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T119 7987-7988 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 8065-8067 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T121 8170-8171 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T5 598-612 Chemical denotes pharmaceutical http://purl.obolibrary.org/obo/CHEBI_52217
T6 1064-1071 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7 1160-1171 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T8 2052-2065 Chemical denotes acetylcholine http://purl.obolibrary.org/obo/CHEBI_15355
T9 2696-2704 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T10 2705-2712 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T11 3047-3055 Chemical denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723
T12 4047-4052 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T13 4251-4259 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T14 5541-5551 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T15 5541-5546 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T16 5547-5551 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T17 5574-5586 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T18 5611-5616 Chemical denotes venom http://purl.obolibrary.org/obo/CHEBI_78505
T19 5617-5628 Chemical denotes neurotoxins http://purl.obolibrary.org/obo/CHEBI_50910
T20 5883-5888 Chemical denotes venom http://purl.obolibrary.org/obo/CHEBI_78505
T21 5889-5895 Chemical denotes toxins http://purl.obolibrary.org/obo/CHEBI_27026
T22 5951-5962 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T23 6019-6026 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T24 6064-6075 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T25 6064-6069 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T26 6070-6075 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T27 6102-6107 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T28 6125-6130 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T29 6321-6328 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30 6641-6649 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T31 6703-6710 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T32 6720-6732 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T33 6947-6955 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T34 6987-6994 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T35 8402-8409 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T36 8462-8469 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T37 8631-8641 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T38 8631-8636 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T39 8637-8641 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T40 8819-8831 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T41 8867-8874 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T6 1350-1365 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T7 1680-1685 http://purl.obolibrary.org/obo/GO_0050909 denotes taste
T8 1998-2020 http://purl.obolibrary.org/obo/GO_0046794 denotes transport of the virus
T9 1998-2007 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T10 2076-2081 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T11 2287-2296 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T12 2341-2350 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T13 2365-2370 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T14 2633-2638 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T15 2729-2738 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T16 2854-2859 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T17 3090-3095 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T18 3499-3504 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T19 3571-3576 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T20 3665-3670 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T21 3744-3753 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T22 4629-4634 http://purl.obolibrary.org/obo/GO_0050909 denotes taste
T23 4885-4894 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T24 4996-5001 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T25 5035-5044 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T26 5275-5284 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T27 5293-5298 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T28 5502-5507 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T29 5852-5857 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T30 5970-5975 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T31 6271-6276 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T32 7728-7733 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T33 8300-8305 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR
T34 8706-8711 http://purl.obolibrary.org/obo/GO_0022848 denotes nAChR

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T10 0-10 Sentence denotes Background
T11 11-192 Sentence denotes The emergence of the novel β-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic of coronavirus disease 2019 (COVID-19) [1].
T12 193-478 Sentence denotes Currently, in mid-May 2020, there are over 4,000,000 confirmed cases of COVID-19 and over 300,000 deaths due to COVID-19 worldwide, according to the COVID-19 Dashboard by the Center for Systems Science and Engineering at Johns Hopkins University (https://coronavirus.jhu.edu/map.html).
T13 479-737 Sentence denotes There is now increasing collaborative activity by governments, academic institutions, biotechnology companies, and the pharmaceutical industry to investigate the range of possible treatments for COVID-19 and vaccines to prevent infection from SARS-CoV-2 [1].
T14 738-901 Sentence denotes Current approaches are drawing on previous studies on severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS-CoV) [1].
T15 902-1248 Sentence denotes For example, studies have shown that SARS-CoV and SARS-CoV-2 have structural similarities within their respective receptor-binding domains (RBDs) of the S1 spike protein subunit that mediate strong multi-point binding to the extracellular globular domain of angiotensin-converting enzyme-2 (ACE2), which may involve neurological expression [2–9].
T16 1249-1447 Sentence denotes Within the lung, widespread expression of ACE2 by alveolar epithelia and capillary cells facilitates viral infection via internalization and replication, leading to severe respiratory disease [2,3].
T17 1448-1824 Sentence denotes Recent evidence of co-morbid neurological sequelae of SARS-CoV-2 infection has been reported in the presence or absence of severe respiratory disease where patients have presented with symptoms of nausea, vomiting, anosmia, loss of taste, impaired consciousness, agitation and confusion, corticospinal tract signs, and cerebrovascular diseases, including encephalopathy [5–7].
T18 1825-2083 Sentence denotes As discussed below, a significant body of empirical studies has demonstrated that the destructive neurological effects of rabies virus (RABV) infections are mediated by CNS transport of the virus tightly bound to the nicotinic acetylcholine receptor (nAChR).
T19 2084-2318 Sentence denotes It has also been recently hypothesized that a similar mechanism may exist to explain the multiple neurological effects of SARS-CoV-2 via binding to peripheral nAChRs followed by orthograde or retrograde transport into the CNS [10,11].
T20 2319-2565 Sentence denotes Potential portals for transport of SARS-CoV-2/nAChR complexes into the CNS include the olfactory nerve and primary olfactory neurons [9,12], and/or peripheral trigeminal sensory terminal structures located within the olfactory epithelium [13,14].
T21 2566-2797 Sentence denotes Further studies are required to fully test the hypothesis that the nAChR receptor represents an obligate biochemical chaperone or effector protein responsible for transport of infective SARS-CoV-2 particles into discrete CNS areas.
T22 2798-2984 Sentence denotes As a corollary, pharmacological targeting of SARS-CoV-2/nAChR complexes may represent a novel vehicle for prevention and control of neurological comorbidities of COVID-19 infection [10].
T23 2985-3248 Sentence denotes There is the potential for new clinical trials to investigate nicotine as a means of blocking SARS-CoV-2-nAChR binding to prevent or treat COVID-19 (https://www.theguardian.com/world/2020/apr/22/french-study-suggests-smokers-at-lower-risk-of-getting-coronavirus).
T24 3249-3513 Sentence denotes As such, we present a critical discussion that integrates lessons learned from prior RABV research and vaccine development into a working model of a SARS-CoV-2 vaccine that selectively targets and neutralizes CNS penetration of a tightly bound viral nAChR complex.
T25 3515-3611 Sentence denotes The Case for a Functional Association of SARS-CoV-2-and nAChR in the Pathophysiology of COVID-19
T26 3612-3869 Sentence denotes Several empirical studies have demonstrated that the nAChR represents a major receptor for the RABV that mechanistically drives CNS transport of infective viral particles, leading to classic neurological sequelae associated with disease progression [15–17].
T27 3870-4088 Sentence denotes Due to the efficient neuroinvasive properties of RABV [18,19], including the ability to bypass the blood-brain barrier, studies have used RABV-based vectors for the delivery of drugs to the CNS, with some success [20].
T28 4089-4387 Sentence denotes Furthermore, genetic engineering of the RABV has been employed to generate novel vaccines consisting of non-replicating RABV particles expressing chimeric capsid proteins containing human immunodeficiency virus 1 (HIV-1) [21,22], MERS-CoV, Ebolavirus, and hepatitis C virus (HCV) sequences [23–25].
T29 4388-4517 Sentence denotes In light of the above, a similar mechanism may underlie the multiple neurological effects of SARS-CoV-2 infection within the CNS.
T30 4518-4635 Sentence denotes Patients with COVID-19 commonly present with sensory neurological symptoms that include anosmia and/or loss of taste.
T31 4636-4957 Sentence denotes It has been proposed that the olfactory epithelium within the nasal cavity represents an early-stage locus for SARS-CoV-2 infection and replication, as reflected by ACE2 expression by a variety of non-neuronal cell types [9], followed by orthograde transport within the primary olfactory pathway into CNS structures [12].
T32 4958-5154 Sentence denotes Additionally, CNS entry of SARS-CoV-2/nAChR complexes may involve retrograde transport from peripheral trigeminal sensory terminal structures located within the olfactory epithelium [13,14,26,27].
T33 5155-5457 Sentence denotes Interestingly, similar lines of empirical evidence support a mechanism for RABV infection within the CNS via retrograde transport of RABV/nAChR complexes from sensory terminals of trigeminal ganglia [28,29], trigeminal nerve terminals within the olfactory epithelium, or primary olfactory neurons [30].
T34 5458-5655 Sentence denotes From a biochemical perspective, a conserved nAChR-binding motif within the primary amino acid sequences of the RABV glycoprotein, HIV-1 gp120, and snake venom neurotoxins has been observed [31–33].
T35 5656-5863 Sentence denotes The HIV-1 envelope, gp120, has been reported to induce neuropathological changes similar to those in patients with HIV-1-associated neurocognitive disorders and triggers an upregulation of the α7-nAChR [34].
T36 5864-5976 Sentence denotes Importantly, snake venom toxins have been demonstrated to be high-affinity competitive antagonists of the nAChR.
T37 5977-6233 Sentence denotes Sequence analysis of the SARS-CoV-2 spike protein identified homologous regions of 4-5 amino acids with aligned sequences in alpha-bungarotoxin and alpha-cobratoxin, thereby suggesting potential binding affinity and antagonism of the α7-nACh receptor [11].
T38 6234-6444 Sentence denotes Sequence homologies between putative nAChR-binding domains within the SARS-CoV-2 spike protein and HIV-1 gp120 have yet to be determined, although there are recent indications for shared CNS comorbidities [35].
T39 6445-6733 Sentence denotes In sum, convergent lines of evidence presented here support the potential construction and testing of novel homologous vaccines employing non-replicating RABV particles expressing chimeric capsid proteins containing antigenic sequences from SARS-CoV-2 spike protein and RABV glycoprotein.
T40 6735-6746 Sentence denotes Conclusions
T41 6747-7104 Sentence denotes Our critical discussion has presented a hypothesis with a potentially high degree of biomedical feasibility, indicating that a novel non-replicating RABV vaccine engineered to contain chimeric capsid proteins with discrete SARS-CoV-2 spike protein domains may represent a highly efficacious preventive measure against neurological comorbidities of COVID 19.
T42 7105-7190 Sentence denotes This hypothesis is based on critical evaluation of the current biomedical literature.
T43 7191-7335 Sentence denotes Currently, however, there are no vaccines in development that are designed to specifically target or neutralize SARS-CoV-2 entry into CNS areas.
T44 7336-7541 Sentence denotes The accepted standard of clinical care employs passive immunization with human rabies immune globulin (HRIG) in conjunction with RABV vaccine administration to prevent animal-to-human transmission of RABV.
T45 7542-7846 Sentence denotes Positive results obtained from in vitro studies designed to evaluate potential inhibitory effects of HRIG on SARS-CoV-2 entry and replication in human neuronal cell lines expressing the nAChR may provide putative proof of principle of our testable hypothesis and justify subsequent human clinical trials.
T46 7847-8069 Sentence denotes Recent studies in the veterinary literature have described a highly infectious SARS-CoV-like canine respiratory coronavirus (CRCoV) that is a major causative agent in the canine infectious respiratory disease complex [36].
T47 8070-8322 Sentence denotes We speculate that the absence of observed neurological sequelae in dogs afflicted with CRCoV may be a functional consequence of widespread prophylactic RABV vaccination that potentially engenders cross-reacting IgGs against viral nAChR-binding domains.
T48 8323-8592 Sentence denotes Finally, conformational matching and stereo-selective recognition of mammalian protein domains by discrete regions of the SARS-CoV-2 spike protein may have been acquired via evolutionary selection of randomly obtained genomic sequences by multiple recombination events.
T49 8593-8880 Sentence denotes Evolutionary conservation of multiple amino acid domains within the primary sequences of variant subtypes of the nAChR, which appears to be evolutionarily ancient, may underlie the observed functional targeting by RABV capsid glycoprotein and putatively by SARS-CoV-2 spike protein [37].

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 1645-1661 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T4 1663-1670 Phenotype denotes anosmia http://purl.obolibrary.org/obo/HP_0000458
T5 1672-1685 Phenotype denotes loss of taste http://purl.obolibrary.org/obo/HP_0000223
T6 1711-1720 Phenotype denotes agitation http://purl.obolibrary.org/obo/HP_0000713
T7 1803-1817 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T8 4277-4293 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T9 4345-4354 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T10 4606-4613 Phenotype denotes anosmia http://purl.obolibrary.org/obo/HP_0000458
T11 4621-4634 Phenotype denotes loss of taste http://purl.obolibrary.org/obo/HP_0000223

2_test

Id Subject Object Predicate Lexical cue
32463026-32105090-69142622 189-190 32105090 denotes 1
32463026-32105090-69142623 734-735 32105090 denotes 1
32463026-32105090-69142624 898-899 32105090 denotes 1
32463026-32155444-69142625 1243-1244 32155444 denotes 2
32463026-32125455-69142625 1243-1244 32125455 denotes 2
32463026-32007145-69142625 1243-1244 32007145 denotes 2
32463026-32283006-69142625 1243-1244 32283006 denotes 2
32463026-32155444-69142626 1442-1443 32155444 denotes 2
32463026-32125455-69142627 1444-1445 32125455 denotes 3
32463026-32283006-69142628 2453-2454 32283006 denotes 9
32463026-15210938-69142629 2455-2457 15210938 denotes 12
32463026-10667995-69142630 2558-2560 10667995 denotes 13
32463026-9853116-69142631 2561-2563 9853116 denotes 14
32463026-3448605-69142632 3862-3864 3448605 denotes 15
32463026-8887475-69142632 3862-3864 8887475 denotes 15
32463026-30772332-69142632 3862-3864 30772332 denotes 15
32463026-19946287-69142633 3925-3927 19946287 denotes 18
32463026-23602163-69142634 3928-3930 23602163 denotes 19
32463026-27581650-69142635 4084-4086 27581650 denotes 20
32463026-10706640-69142636 4311-4313 10706640 denotes 21
32463026-14610200-69142637 4314-4316 14610200 denotes 22
32463026-26063224-69142638 4380-4382 26063224 denotes 23
32463026-11878905-69142638 4380-4382 11878905 denotes 23
32463026-32283006-69142639 4858-4859 32283006 denotes 9
32463026-15210938-69142640 4953-4955 15210938 denotes 12
32463026-10667995-69142641 5141-5143 10667995 denotes 13
32463026-9853116-69142642 5144-5146 9853116 denotes 14
32463026-16885765-69142643 5147-5149 16885765 denotes 26
32463026-17150985-69142644 5150-5152 17150985 denotes 27
32463026-7941329-69142645 5355-5357 7941329 denotes 28
32463026-2016778-69142646 5358-5360 2016778 denotes 29
32463026-2053286-69142647 5453-5455 2053286 denotes 30
32463026-9345046-69142648 5648-5650 9345046 denotes 31
32463026-2241576-69142648 5648-5650 2241576 denotes 31
32463026-1397297-69142648 5648-5650 1397297 denotes 31
32463026-29379089-69142649 5859-5861 29379089 denotes 34