PMC:7275137 / 0-350 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":17,"end":25},"obj":"Body_part"},{"id":"T2","span":{"begin":114,"end":122},"obj":"Body_part"},{"id":"T3","span":{"begin":210,"end":218},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma63836"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma63836"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma63836"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":89,"end":97},"obj":"Disease"},{"id":"T2","span":{"begin":303,"end":350},"obj":"Disease"},{"id":"T3","span":{"begin":303,"end":336},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":17,"end":25},"obj":"http://purl.obolibrary.org/obo/GO_0005764"},{"id":"T2","span":{"begin":114,"end":122},"obj":"http://purl.obolibrary.org/obo/GO_0005764"},{"id":"T3","span":{"begin":210,"end":218},"obj":"http://purl.obolibrary.org/obo/GO_0005764"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":255,"end":260},"obj":"Chemical"},{"id":"T2","span":{"begin":283,"end":298},"obj":"Chemical"},{"id":"T3","span":{"begin":283,"end":292},"obj":"Chemical"},{"id":"T4","span":{"begin":293,"end":298},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_36044"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":181,"end":206},"obj":"http://purl.obolibrary.org/obo/GO_1903901"},{"id":"T2","span":{"begin":189,"end":206},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T3","span":{"begin":189,"end":206},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":97},"obj":"Sentence"},{"id":"T2","span":{"begin":100,"end":110},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1","span":{"begin":89,"end":97},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"tao:has_database_id","subj":"1","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Widely available lysosome targeting agents should be considered as potential therapy for COVID-19 \n\nHighlights\n• Lysosome targeting agents can disrupt endolysosomal maturation and inhibit viral replication • Lysosome targeting agents and lysosomotropic drugs should be explored as antiviral drugs for severe acute respiratory syndrome coronavirus-2"}