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PMC:7275133 / 20849-23991 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
424 3024-3026 Gene denotes of Gene:6688
425 3013-3015 Gene denotes of Gene:6688
426 3005-3007 Gene denotes of Gene:6688
427 2854-2856 Gene denotes of Gene:6688
428 2652-2654 Gene denotes of Gene:6688
429 2374-2376 Gene denotes of Gene:6688
430 2342-2344 Gene denotes of Gene:6688
431 1965-1967 Gene denotes of Gene:6688
432 1718-1720 Gene denotes of Gene:6688
433 1572-1574 Gene denotes of Gene:6688
434 1400-1402 Gene denotes of Gene:6688
435 1346-1348 Gene denotes of Gene:6688
436 1184-1186 Gene denotes of Gene:6688
437 140-145 Species denotes Apple Tax:3750
438 631-636 Species denotes Apple Tax:3750
439 902-907 Species denotes Apple Tax:3750
440 989-996 Species denotes patient Tax:9606
441 1061-1068 Species denotes patient Tax:9606
442 1943-1950 Species denotes patient Tax:9606
443 2183-2191 Species denotes patients Tax:9606
444 2549-2557 Species denotes patients Tax:9606
445 84-90 Disease denotes asthma MESH:D001249
446 588-594 Disease denotes asthma MESH:D001249
447 814-829 Disease denotes asthma symptoms MESH:D051271
448 853-859 Disease denotes asthma MESH:D001249
449 1492-1507 Disease denotes asthma symptoms MESH:D051271
450 1762-1768 Disease denotes asthma MESH:D001249
451 2209-2215 Disease denotes asthma MESH:D001249
452 2719-2725 Disease denotes asthma MESH:D001249
453 2781-2787 Disease denotes asthma MESH:D001249
455 45-51 Disease denotes asthma MESH:D001249

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T11 161-166 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T12 332-337 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T13 796-800 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T14 2813-2817 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T9 161-166 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T10 332-337 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T11 796-800 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 2813-2817 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T53 45-51 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T54 84-90 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T55 578-594 Disease denotes pediatric asthma http://purl.obolibrary.org/obo/MONDO_0005405
T56 588-594 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T57 814-820 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T58 853-859 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T59 1363-1369 Disease denotes Asthma http://purl.obolibrary.org/obo/MONDO_0004979
T60 1427-1430 Disease denotes GPS http://purl.obolibrary.org/obo/MONDO_0007686
T61 1492-1498 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T62 1762-1768 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T63 2209-2215 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T64 2658-2664 Disease denotes Asthma http://purl.obolibrary.org/obo/MONDO_0004979
T65 2719-2725 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T66 2781-2787 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T167 161-166 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T168 161-166 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T169 161-166 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T170 161-166 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T171 232-240 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T172 332-337 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T173 332-337 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T174 332-337 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T175 332-337 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T176 369-377 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T177 521-523 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T178 796-800 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T179 796-800 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T180 833-842 http://www.ebi.ac.uk/efo/EFO_0000881 denotes digitally
T181 1099-1106 http://purl.obolibrary.org/obo/OBI_0000968 denotes devices
T182 1132-1139 http://www.ebi.ac.uk/efo/EFO_0000881 denotes digital
T183 1705-1711 http://purl.obolibrary.org/obo/OBI_0000968 denotes device
T184 1968-1974 http://purl.obolibrary.org/obo/OBI_0000968 denotes device
T185 1979-1986 http://www.ebi.ac.uk/efo/EFO_0000881 denotes digital
T186 2238-2239 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T187 2240-2247 http://www.ebi.ac.uk/efo/EFO_0000881 denotes digital
T188 2349-2356 http://purl.obolibrary.org/obo/OBI_0000968 denotes devices
T189 2377-2384 http://purl.obolibrary.org/obo/OBI_0000968 denotes devices
T190 2813-2817 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T191 2813-2817 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T29 683-690 Chemical denotes Android http://purl.obolibrary.org/obo/CHEBI_27436
T30 1525-1533 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T31 2132-2140 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T32 2297-2305 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T33 2538-2546 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T25 289-294 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T26 448-453 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T27 541-546 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T28 878-883 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T138 0-51 Sentence denotes Table 2 Current and emerging technologies in asthma
T139 52-107 Sentence denotes Technology Measures Outcomes in asthma studies Comments
T140 108-127 Sentence denotes Wearable technology
T141 128-137 Sentence denotes − Fitbit™
T142 138-318 Sentence denotes − Apple™ Watch Fitbit: heart rate (available on most but not all models), steps/day, physical activity (light, moderate and vigorous), sedentary time, sleep efficiency, wake counts
T143 319-523 Sentence denotes Apple Watch: heart rate, EKG, steps/day, physical activity (light, moderate and vigorous), sedentary time − Fitbit overestimated sleep efficiency and underestimated wake counts compared with actigraphy.18
T144 524-630 Sentence denotes − Fitbit-derived sleep quality correlated with PROMIS pediatric asthma impact score.21 Corresponding Apps:
T145 631-690 Sentence denotes Apple Watch App on iPhone, Fitbit App on iPhone and Android
T146 691-868 Sentence denotes Pros: portable; commercially available; may be useful when used with other measures such as air quality, lung function and asthma symptoms to digitally phenotype asthma patients
T147 869-874 Sentence denotes Cons:
T148 875-935 Sentence denotes No sleep data available on Apple Watch without 3rd party App
T149 936-949 Sentence denotes Data sharing:
T150 950-1076 Sentence denotes Data does not sync to EMR directly but patient can access file and send to provider via mail, secure email, or patient portal.
T151 1077-1168 Sentence denotes Electronic monitoring devices (e.g., inhaler sensors ± digital health platform) Digihaler™:
T152 1169-1280 Sentence denotes − Inhaler time of inhaler use, peak inspiratory flow rate (PIFR), time to PIFR, inhalation volume and duration.
T153 1281-1305 Sentence denotes Propeller Health System:
T154 1306-1360 Sentence denotes − Inhaler sensor: date, time and number of doses taken
T155 1361-1390 Sentence denotes − Asthma Health Platform App:
T156 1391-1516 Sentence denotes Location of inhaler use using phone GPS, current weather/pollen counts/air pollution and self-report asthma symptoms/triggers
T157 1517-1534 Sentence denotes Hailie™ solution:
T158 1535-1610 Sentence denotes − Inhaler sensor: date, time, number of inhaler actuations and missed doses
T159 1611-1674 Sentence denotes − Hailie™ App: medication adherence, daily medication reminders
T160 1675-1712 Sentence denotes Inhaler compliance assessment device:
T161 1713-1808 Sentence denotes Time of dose, inhaler technique errors − Greater asthma control31,38–39 and symptom-free days33
T162 1809-1898 Sentence denotes − Reduction in daily symptoms31, rescue medication use29,32–33, and exacerbations34,38–39
T163 1899-1935 Sentence denotes − Improved medication adherence36–40
T164 1936-2008 Sentence denotes − High patient acceptability of device and digital health platform36–37.
T165 2009-2028 Sentence denotes Corresponding Apps:
T166 2029-2067 Sentence denotes Digihaler™, Propeller Health, Hailie™.
T167 2068-2141 Sentence denotes Web-based platform also available for Propeller Health, Hailie™ solution.
T168 2142-2307 Sentence denotes Pros: portable, high acceptability among patients, improvements in asthma control in those with a digital health platform (e.g., Propeller Health, Hailie™ solution).
T169 2308-2313 Sentence denotes Cons:
T170 2314-2434 Sentence denotes Additional efficacy studies of the devices are needed, cost of devices are not always covered by insurance reimbursement
T171 2435-2448 Sentence denotes Data sharing:
T172 2449-2609 Sentence denotes Provider platform available to share results (e.g. Digihaler™, Propeller Health, Hailie™ solution), patients may share data from Digihaler™ also via file share.
T173 2610-2655 Sentence denotes Mobile-based applications Self-monitoring of:
T174 2656-2673 Sentence denotes − Asthma symptoms
T175 2674-2684 Sentence denotes − Triggers
T176 2685-2763 Sentence denotes − Medication use -Improvements in asthma control though low-quality evidence45
T177 2764-2886 Sentence denotes -Improvements in asthma control in five studies, lung function in two studies and quality of life in three studies46 Pros:
T178 2887-2917 Sentence denotes Acceptable and feasible to use
T179 2918-2923 Sentence denotes Cons:
T180 2924-3045 Sentence denotes Vary in quality; data are self-reported, most apps have not been validated; risk of loss of privacy of health information
T181 3046-3059 Sentence denotes Data sharing:
T182 3060-3142 Sentence denotes Vary in ability to share with provider, most are up to user to share with provider

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T50 45-51 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T51 84-90 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T52 588-594 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T53 814-820 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T54 853-859 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T55 1363-1369 Phenotype denotes Asthma http://purl.obolibrary.org/obo/HP_0002099
T56 1492-1498 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T57 1762-1768 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T58 2209-2215 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T59 2658-2664 Phenotype denotes Asthma http://purl.obolibrary.org/obo/HP_0002099
T60 2719-2725 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T61 2781-2787 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099