> top > docs > PMC:7274970 > annotations

PMC:7274970 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 112-120 Species denotes patients Tax:9606
4 49-60 Disease denotes lymphopenia MESH:D008231
5 126-134 Disease denotes COVID-19 MESH:C000657245
9 253-261 Species denotes patients Tax:9606
10 229-240 Disease denotes lymphopenia MESH:D008231
11 244-252 Disease denotes COVID-19 MESH:C000657245
14 342-350 Species denotes patients Tax:9606
15 333-341 Disease denotes COVID-19 MESH:C000657245
18 431-439 Species denotes patients Tax:9606
19 422-430 Disease denotes COVID-19 MESH:C000657245
35 774-782 Species denotes patients Tax:9606
36 1244-1252 Species denotes patients Tax:9606
37 1527-1535 Species denotes patients Tax:9606
38 1561-1569 Species denotes patients Tax:9606
39 2130-2138 Species denotes patients Tax:9606
40 2218-2226 Species denotes patients Tax:9606
41 2266-2274 Species denotes Patients Tax:9606
42 2725-2733 Species denotes patients Tax:9606
43 577-585 Disease denotes COVID-19 MESH:C000657245
44 724-735 Disease denotes lymphopenia MESH:D008231
45 809-817 Disease denotes COVID-19 MESH:C000657245
46 2487-2496 Disease denotes infection MESH:D007239
47 2716-2724 Disease denotes COVID-19 MESH:C000657245
48 2739-2750 Disease denotes lymphopenia MESH:D008231
49 2791-2802 Disease denotes lymphopenia MESH:D008231
65 2856-2903 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
66 2905-2915 Species denotes SARS-CoV-2 Tax:2697049
67 3362-3370 Species denotes patients Tax:9606
68 3786-3794 Species denotes patients Tax:9606
69 2947-2955 Disease denotes COVID-19 MESH:C000657245
70 2995-3021 Disease denotes acute respiratory distress MESH:D012128
71 3023-3045 Disease denotes multiple organ failure MESH:D009102
72 3050-3055 Disease denotes death MESH:D003643
73 3166-3175 Disease denotes mortality MESH:D003643
74 3184-3192 Disease denotes COVID-19 MESH:C000657245
75 3215-3248 Disease denotes severe acute respiratory syndrome MESH:D045169
76 3284-3316 Disease denotes Middle East respiratory syndrome MESH:D018352
77 3318-3322 Disease denotes MERS MESH:D018352
78 3456-3460 Disease denotes MERS MESH:D018352
79 3804-3818 Disease denotes critically ill MESH:D016638
93 3843-3851 Species denotes Patients Tax:9606
94 4156-4164 Species denotes patients Tax:9606
95 4504-4512 Species denotes patients Tax:9606
96 4769-4777 Species denotes patients Tax:9606
97 3857-3865 Disease denotes COVID-19 MESH:C000657245
98 4138-4143 Disease denotes death MESH:D003643
99 4147-4155 Disease denotes COVID-19 MESH:C000657245
100 4213-4224 Disease denotes lymphopenia MESH:D008231
101 4275-4283 Disease denotes COVID-19 MESH:C000657245
102 4491-4500 Disease denotes mortality MESH:D003643
103 4518-4526 Disease denotes COVID-19 MESH:C000657245
104 4639-4650 Disease denotes lymphopenia MESH:D008231
105 4783-4791 Disease denotes COVID-19 MESH:C000657245
124 4882-4890 Species denotes patients Tax:9606
125 5829-5837 Species denotes patients Tax:9606
126 5956-5964 Species denotes patients Tax:9606
127 6359-6367 Species denotes patients Tax:9606
128 6571-6579 Species denotes patients Tax:9606
129 4867-4878 Disease denotes lymphopenia MESH:D008231
130 4896-4904 Disease denotes COVID-19 MESH:C000657245
131 5201-5226 Disease denotes Sleep disturbance impairs MESH:D012893
132 5278-5290 Disease denotes inflammation MESH:D007249
133 5459-5476 Disease denotes sleep deprivation MESH:D012892
134 5701-5729 Disease denotes upper respiratory infections MESH:D012141
135 5882-5891 Disease denotes mortality MESH:D003643
136 5970-5978 Disease denotes COVID-19 MESH:C000657245
137 6152-6159 Disease denotes anxiety MESH:D001007
138 6181-6191 Disease denotes depression MESH:D000275
139 6373-6381 Disease denotes COVID-19 MESH:C000657245
140 6479-6490 Disease denotes lymphopenia MESH:D008231
141 6585-6593 Disease denotes COVID-19 MESH:C000657245
143 7961-7985 Disease denotes coronavirus disease-2019 MESH:C000657245
156 6718-6726 Species denotes patients Tax:9606
157 6959-6967 Species denotes patients Tax:9606
158 7235-7240 Species denotes women Tax:9606
159 7394-7402 Species denotes patients Tax:9606
160 7854-7862 Species denotes patients Tax:9606
161 6753-6761 Disease denotes COVID-19 MESH:C000657245
162 7179-7184 Disease denotes death MESH:D003643
163 7333-7354 Disease denotes loss of consciousness MESH:D014474
164 7541-7549 Disease denotes COVID-19 MESH:C000657245
165 7606-7633 Disease denotes Novel Coronavirus Pneumonia MESH:C000657245
166 7734-7742 Disease denotes COVID-19 MESH:C000657245
167 7882-7890 Disease denotes COVID-19 MESH:C000657245
169 8351-8369 Disease denotes infectious disease MESH:D003141
172 8517-8525 Species denotes patients Tax:9606
173 8541-8549 Disease denotes COVID-19 MESH:C000657245
188 10083-10090 Species denotes patient Tax:9606
189 8690-8717 Disease denotes chronic respiratory disease MESH:D012140
190 8719-8762 Disease denotes cardiovascular and cerebrovascular diseases MESH:D002318
191 8811-8834 Disease denotes nervous system diseases MESH:D009422
192 9521-9540 Disease denotes acute kidney injury MESH:D058186
193 9554-9571 Disease denotes liver dysfunction MESH:D017093
194 9579-9593 Disease denotes cardiac injury MESH:D006331
195 9595-9608 Disease denotes hyperglycemia MESH:D006943
196 9632-9641 Disease denotes infection MESH:D007239
197 9700-9714 Disease denotes Kidney Disease MESH:D007674
198 9767-9781 Disease denotes Cardiac injury MESH:D006331
199 9821-9835 Disease denotes hypersensitive MESH:D004342
200 9959-9976 Disease denotes liver dysfunction MESH:D017093
201 10029-10038 Disease denotes infection MESH:D007239
204 10759-10767 Species denotes patients Tax:9606
205 11167-11183 Disease denotes disruptive sleep MESH:D012893
211 11873-11881 Species denotes Patients Tax:9606
212 12043-12051 Species denotes Patients Tax:9606
213 12305-12313 Species denotes patients Tax:9606
214 11596-11614 Disease denotes sleep disturbances MESH:D012893
215 11645-11664 Disease denotes daytime dysfunction MESH:D053207
231 13753-13761 Species denotes patients Tax:9606
232 13918-13926 Species denotes patients Tax:9606
233 13932-13940 Species denotes patients Tax:9606
234 14003-14011 Species denotes patients Tax:9606
235 14070-14078 Species denotes patients Tax:9606
236 14164-14172 Species denotes patients Tax:9606
237 14264-14272 Species denotes patients Tax:9606
238 14315-14320 Species denotes women Tax:9606
239 14326-14334 Species denotes patients Tax:9606
240 14392-14400 Species denotes patients Tax:9606
241 14453-14461 Species denotes patients Tax:9606
242 14520-14528 Species denotes patients Tax:9606
243 14598-14606 Species denotes patients Tax:9606
244 14131-14136 Disease denotes death MESH:D003643
245 14340-14361 Disease denotes loss of consciousness MESH:D014474
265 16028-16033 Disease denotes Death MESH:D003643
266 16353-16396 Disease denotes Cardiovascular and cerebrovascular diseases MESH:D002318
267 16435-16452 Disease denotes Endocrine disease MESH:D004700
268 16536-16563 Disease denotes Chronic respiratory disease MESH:D012140
269 16596-16620 Disease denotes Gastrointestinal disease MESH:D005767
270 16852-16857 Disease denotes Fever MESH:D005334
271 16897-16902 Disease denotes Cough MESH:D003371
272 16941-16960 Disease denotes Shortness of breath MESH:D004417
273 16999-17006 Disease denotes Fatigue MESH:D005221
274 17097-17104 Disease denotes Myalgia MESH:D063806
275 17108-17118 Disease denotes arthralgia MESH:D018771
276 17157-17166 Disease denotes Diarrhoea MESH:D003967
277 17250-17268 Disease denotes Nausea or Vomiting MESH:D020250
278 17304-17312 Disease denotes Anorexia MESH:D000855
279 17347-17355 Disease denotes Headache MESH:D006261
280 17389-17398 Disease denotes Dizziness MESH:D004244
281 17437-17441 Disease denotes pain MESH:D010146
282 17474-17486 Disease denotes Pharyngalgia MESH:D010608
283 17605-17619 Disease denotes Abdominal pain MESH:D015746
286 15453-15461 Species denotes patients Tax:9606
287 15467-15475 Disease denotes COVID-19 MESH:C000657245
289 18483-18491 Species denotes patients Tax:9606
293 18626-18634 Species denotes patients Tax:9606
294 18677-18685 Species denotes patients Tax:9606
295 18599-18605 Chemical denotes oxygen MESH:D010100
301 14836-14844 Species denotes patients Tax:9606
302 14891-14899 Species denotes patients Tax:9606
303 14905-14908 Species denotes men Tax:9606
304 15036-15044 Species denotes patients Tax:9606
305 15080-15088 Species denotes patients Tax:9606
307 20849-20857 Disease denotes insomnia MESH:D007319
310 19564-19572 Species denotes patients Tax:9606
311 19578-19586 Disease denotes COVID-19 MESH:C000657245
315 21218-21226 Species denotes patients Tax:9606
316 20973-20980 Disease denotes anxiety MESH:D001007
317 20999-21009 Disease denotes depression MESH:D000275
322 18753-18761 Species denotes Patients Tax:9606
323 19139-19147 Species denotes patients Tax:9606
324 19494-19502 Species denotes patients Tax:9606
325 19447-19455 Disease denotes insomnia MESH:D007319
337 23918-23929 Gene denotes Prothrombin Gene:2147
338 24378-24382 Chemical denotes urea MESH:D014508
339 24383-24391 Chemical denotes nitrogen MESH:D009584
340 24475-24485 Chemical denotes creatinine MESH:D003404
341 24758-24765 Chemical denotes Glucose MESH:D005947
342 25203-25217 Disease denotes Hypersensitive MESH:D004342
343 25288-25326 Disease denotes Complications  Acute liver dysfunction MESH:D017114
344 25367-25381 Disease denotes Hyperglycaemia
345 25440-25449 Disease denotes infection MESH:D007239
346 25484-25503 Disease denotes Acute kidney injury MESH:D058186
347 25542-25556 Disease denotes cardiac injury MESH:D006331
350 23099-23107 Species denotes patients Tax:9606
351 23113-23121 Disease denotes COVID-19 MESH:C000657245
353 26453-26461 Species denotes patients Tax:9606
361 26595-26606 Gene denotes prothrombin Gene:2147
362 26632-26640 Species denotes patients Tax:9606
363 26654-26662 Species denotes patients Tax:9606
364 26678-26686 Species denotes patients Tax:9606
365 26728-26736 Species denotes patients Tax:9606
366 26749-26757 Species denotes patients Tax:9606
367 26773-26781 Species denotes patients Tax:9606
370 26884-26892 Species denotes patients Tax:9606
371 26933-26941 Species denotes patients Tax:9606
401 21737-21745 Species denotes Patients Tax:9606
402 21949-21956 Species denotes patient Tax:9606
403 22063-22084 Species denotes klebsiella pneumoniae Tax:573
404 22153-22161 Species denotes patients Tax:9606
405 22210-22232 Species denotes Acinetobacter Baumanii Tax:470
406 22237-22255 Species denotes Candida tropicalis Tax:5482
407 22261-22269 Species denotes patients Tax:9606
408 22303-22310 Species denotes patient Tax:9606
409 22355-22376 Species denotes klebsiella pneumoniae Tax:573
410 22382-22389 Species denotes patient Tax:9606
411 22422-22440 Species denotes Candida tropicalis Tax:5482
412 22489-22496 Species denotes patient Tax:9606
413 22578-22601 Species denotes Acinetobacter baumannii Tax:470
414 22640-22648 Species denotes patients Tax:9606
415 22745-22753 Species denotes patients Tax:9606
416 22808-22816 Species denotes patients Tax:9606
417 22189-22199 Chemical denotes carbapenem MESH:D015780
418 22557-22567 Chemical denotes carbapenem MESH:D015780
419 21445-21463 Disease denotes acute liver injury MESH:D056486
420 21504-21517 Disease denotes hyperglycemia MESH:D006943
421 21558-21577 Disease denotes acute kidney injury MESH:D058186
422 21626-21640 Disease denotes cardiac injury MESH:D006331
423 21994-22013 Disease denotes pulmonary infection MESH:D012141
424 22166-22185 Disease denotes pulmonary infection MESH:D012141
425 22288-22297 Disease denotes infection MESH:D007239
426 22328-22337 Disease denotes infection MESH:D007239
427 22399-22418 Disease denotes pulmonary infection MESH:D012141
428 22458-22467 Disease denotes infection MESH:D007239
429 22501-22552 Disease denotes pulmonary infection of Stenotrophomonas maltophilia MESH:C531821
440 28504-28512 Species denotes patients Tax:9606
441 28693-28701 Species denotes patients Tax:9606
442 28783-28791 Species denotes patients Tax:9606
443 28819-28827 Species denotes patients Tax:9606
444 28896-28904 Species denotes patients Tax:9606
445 28928-28936 Species denotes patients Tax:9606
446 28964-28972 Species denotes patients Tax:9606
447 28314-28325 Disease denotes lymphopenia MESH:D008231
448 28518-28526 Disease denotes COVID-19 MESH:C000657245
449 28707-28715 Disease denotes COVID-19 MESH:C000657245
454 27054-27062 Species denotes patients Tax:9606
455 27088-27096 Species denotes patients Tax:9606
456 27338-27346 Species denotes Patients Tax:9606
457 27647-27655 Species denotes patients Tax:9606
485 29663-29671 Species denotes patients Tax:9606
486 29701-29709 Species denotes patients Tax:9606
487 29743-29751 Species denotes patients Tax:9606
488 29805-29813 Species denotes patients Tax:9606
489 30605-30613 Species denotes patients Tax:9606
490 30761-30769 Species denotes patients Tax:9606
491 30896-30904 Species denotes patients Tax:9606
492 30933-30941 Species denotes patients Tax:9606
493 31245-31253 Species denotes patients Tax:9606
494 31338-31346 Species denotes patients Tax:9606
495 31390-31398 Species denotes Patients Tax:9606
496 31690-31698 Species denotes patients Tax:9606
497 31780-31790 Species denotes SARS-CoV-2 Tax:2697049
498 32236-32244 Species denotes patients Tax:9606
499 29571-29582 Disease denotes lymphopenia MESH:D008231
500 29677-29685 Disease denotes COVID-19 MESH:C000657245
501 30501-30512 Disease denotes lymphopenia MESH:D008231
502 30910-30918 Disease denotes COVID-19 MESH:C000657245
503 31115-31126 Disease denotes lymphopenia MESH:D008231
504 31259-31267 Disease denotes COVID-19 MESH:C000657245
505 31704-31712 Disease denotes COVID-19 MESH:C000657245
506 31856-31877 Disease denotes COVID-19 encephalitis MESH:C000657245
507 31905-31924 Disease denotes neurologic syndrome MESH:D009422
508 31954-31962 Disease denotes COVID-19 MESH:C000657245
509 31999-32021 Disease denotes polyneuritis cranialis MESH:D009443
510 32027-32033 Disease denotes stroke MESH:D020521
511 32250-32258 Disease denotes COVID-19 MESH:C000657245
521 32263-32271 Species denotes patients Tax:9606
522 32571-32579 Species denotes patients Tax:9606
523 32671-32679 Species denotes patients Tax:9606
524 33060-33068 Species denotes patients Tax:9606
525 33280-33288 Species denotes patients Tax:9606
526 32277-32285 Disease denotes COVID-19 MESH:C000657245
527 32585-32593 Disease denotes COVID-19 MESH:C000657245
528 32646-32663 Disease denotes sleep disturbance MESH:D012893
529 33294-33302 Disease denotes COVID-19 MESH:C000657245
548 33401-33409 Species denotes patients Tax:9606
549 33542-33550 Species denotes patients Tax:9606
550 33657-33665 Species denotes patients Tax:9606
551 33865-33873 Species denotes patients Tax:9606
552 34044-34052 Species denotes patients Tax:9606
553 34109-34117 Species denotes patients Tax:9606
554 34174-34182 Species denotes patients Tax:9606
555 34540-34548 Species denotes patients Tax:9606
556 34876-34884 Species denotes Patients Tax:9606
557 35431-35439 Species denotes patients Tax:9606
558 35491-35499 Species denotes patients Tax:9606
559 35593-35601 Species denotes patients Tax:9606
560 35654-35662 Species denotes patients Tax:9606
561 33415-33423 Disease denotes COVID-19 MESH:C000657245
562 33879-33887 Disease denotes COVID-19 MESH:C000657245
563 34058-34066 Disease denotes COVID-19 MESH:C000657245
564 34554-34562 Disease denotes COVID-19 MESH:C000657245
565 35445-35453 Disease denotes COVID-19 MESH:C000657245
567 36113-36120 Species denotes patient Tax:9606
577 36437-36445 Species denotes patients Tax:9606
578 36737-36745 Species denotes patients Tax:9606
579 36451-36459 Disease denotes COVID-19 MESH:C000657245
580 36501-36512 Disease denotes lymphopenia MESH:D008231
581 36544-36558 Disease denotes critically ill MESH:D016638
582 36768-36779 Disease denotes lymphopenia MESH:D008231
583 36802-36810 Disease denotes COVID-19 MESH:C000657245
584 36811-36820 Disease denotes infection MESH:D007239
585 36940-36948 Disease denotes COVID-19 MESH:C000657245
592 37259-37261 Disease denotes HH MESH:D006432
593 37013-37015 CellLine denotes SY CVCL:7028
594 37177-37179 CellLine denotes SY CVCL:7028
595 37263-37265 CellLine denotes HL CVCL:2492
596 37474-37476 CellLine denotes SY CVCL:7028
597 37498-37500 CellLine denotes SY CVCL:7028
599 37660-37671 Species denotes Participant Tax:9606

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 1613-1623 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T2 1863-1873 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T3 1877-1887 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T4 3032-3037 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T5 3907-3917 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T6 4013-4024 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T7 4321-4331 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T8 4335-4345 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T9 5022-5035 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T10 5337-5346 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T11 5508-5527 Body_part denotes natural killer cell http://purl.org/sig/ont/fma/fma63147
T12 5523-5527 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T13 5544-5549 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T14 7036-7041 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T15 7042-7053 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T16 7781-7787 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T17 7812-7835 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T18 7933-7943 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T19 8624-8628 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T20 8811-8825 Body_part denotes nervous system http://purl.org/sig/ont/fma/fma7157
T21 8936-8941 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T22 9122-9127 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T23 9143-9148 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T24 9163-9167 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T25 9230-9235 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T26 9245-9250 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T27 9432-9446 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T28 9527-9533 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T29 9554-9559 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T30 9700-9706 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T31 9815-9820 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T32 9844-9854 Body_part denotes troponin I http://purl.org/sig/ont/fma/fma62340
T33 9844-9852 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T34 9959-9964 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T35 12727-12732 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T36 12733-12744 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T37 12749-12760 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T38 15161-15166 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T39 17431-17436 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T40 17676-17680 Body_part denotes Body http://purl.org/sig/ont/fma/fma256135
T41 17874-17879 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T42 18244-18249 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T43 21412-21417 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T44 21451-21456 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T45 21564-21570 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T46 22274-22287 Body_part denotes urinary tract http://purl.org/sig/ont/fma/fma0326482
T47 22315-22320 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T48 22445-22450 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T49 23200-23205 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T50 23222-23227 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T51 23311-23321 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T52 23405-23415 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T53 23499-23509 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T54 23593-23603 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T55 23684-23692 Body_part denotes Platelet http://purl.org/sig/ont/fma/fma62851
T56 24073-24078 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T57 24193-24200 Body_part denotes Alanine http://purl.org/sig/ont/fma/fma82749
T58 24372-24377 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T59 24469-24474 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T60 24758-24765 Body_part denotes Glucose http://purl.org/sig/ont/fma/fma82743
T61 25226-25236 Body_part denotes troponin I http://purl.org/sig/ont/fma/fma62340
T62 25226-25234 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T63 25309-25314 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T64 25490-25496 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T65 26007-26021 Body_part denotes Immunoglobulin http://purl.org/sig/ont/fma/fma62871
T66 26990-27000 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T67 27011-27021 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T68 27025-27035 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T69 28355-28365 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T70 28385-28395 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T71 28399-28409 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T72 31816-31835 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T73 38377-38385 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542
T74 38616-38624 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 3032-3037 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T2 5022-5035 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T3 5544-5549 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T4 7036-7041 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T5 7781-7787 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T6 7812-7835 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T7 7818-7835 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T8 8811-8825 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T9 8936-8941 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T10 9122-9127 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T11 9143-9148 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T12 9230-9235 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T13 9245-9250 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T14 9527-9533 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T15 9554-9559 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T16 9700-9706 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T17 9815-9820 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T18 9959-9964 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T19 10897-10902 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T20 12727-12732 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T21 15161-15166 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T22 17431-17436 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T23 17874-17879 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T24 18244-18249 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T25 21412-21417 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T26 21451-21456 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T27 21564-21570 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T28 22315-22320 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T29 22445-22450 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T30 23200-23205 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T31 23222-23227 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T32 24073-24078 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T33 24372-24377 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T34 24469-24474 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T35 25309-25314 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T36 25490-25496 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T37 31816-31835 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 49-60 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T2 126-134 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 229-240 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T4 244-252 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 333-341 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 422-430 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 577-585 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 724-735 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T9 809-817 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 2469-2496 Disease denotes hospital-acquired infection http://purl.obolibrary.org/obo/MONDO_0043544
T11 2487-2496 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 2716-2724 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 2739-2750 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T14 2791-2802 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T15 2856-2903 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T16 2905-2913 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 2905-2909 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 2947-2955 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 3023-3045 Disease denotes multiple organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T20 3184-3192 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 3215-3248 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T22 3250-3254 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 3448-3452 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T24 3857-3865 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 4147-4155 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 4213-4224 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T27 4275-4283 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 4518-4526 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 4639-4650 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T30 4783-4791 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 4867-4878 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T32 4896-4904 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 5201-5218 Disease denotes Sleep disturbance http://purl.obolibrary.org/obo/MONDO_0003406
T34 5278-5290 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T35 5701-5729 Disease denotes upper respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T36 5970-5978 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 6152-6159 Disease denotes anxiety http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918
T39 6181-6191 Disease denotes depression http://purl.obolibrary.org/obo/MONDO_0002050
T40 6373-6381 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 6479-6490 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T42 6585-6593 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 6753-6761 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T44 7541-7549 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T45 7624-7633 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T46 7734-7742 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 7882-7890 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 7951-7959 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 7961-7985 Disease denotes coronavirus disease-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T50 8351-8369 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T51 8541-8549 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 8698-8717 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T53 8738-8762 Disease denotes cerebrovascular diseases http://purl.obolibrary.org/obo/MONDO_0011057
T54 8811-8834 Disease denotes nervous system diseases http://purl.obolibrary.org/obo/MONDO_0005071
T55 9521-9540 Disease denotes acute kidney injury http://purl.obolibrary.org/obo/MONDO_0002492
T56 9534-9540 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T57 9542-9545 Disease denotes AKI http://purl.obolibrary.org/obo/MONDO_0002492
T58 9587-9593 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T59 9595-9608 Disease denotes hyperglycemia http://purl.obolibrary.org/obo/MONDO_0002909
T60 9614-9641 Disease denotes hospital-acquired infection http://purl.obolibrary.org/obo/MONDO_0043544
T61 9632-9641 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T62 9643-9646 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T63 9650-9653 Disease denotes AKI http://purl.obolibrary.org/obo/MONDO_0002492
T64 9700-9714 Disease denotes Kidney Disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T66 9775-9781 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T67 9821-9835 Disease denotes hypersensitive http://purl.obolibrary.org/obo/MONDO_0000605
T68 10010-10013 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T69 10029-10038 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T70 11596-11614 Disease denotes sleep disturbances http://purl.obolibrary.org/obo/MONDO_0003406
T71 13005-13008 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T72 15467-15475 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 16372-16396 Disease denotes cerebrovascular diseases http://purl.obolibrary.org/obo/MONDO_0011057
T74 16435-16452 Disease denotes Endocrine disease http://purl.obolibrary.org/obo/MONDO_0005151
T75 16544-16563 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T76 16596-16620 Disease denotes Gastrointestinal disease http://purl.obolibrary.org/obo/MONDO_0004335
T77 16653-16670 Disease denotes Urologic diseases http://purl.obolibrary.org/obo/MONDO_0002118
T78 17157-17166 Disease denotes Diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T79 19447-19455 Disease denotes insomnia http://purl.obolibrary.org/obo/MONDO_0013600
T80 19578-19586 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T81 20849-20857 Disease denotes insomnia http://purl.obolibrary.org/obo/MONDO_0013600
T82 20973-20980 Disease denotes anxiety http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918
T84 20999-21009 Disease denotes depression http://purl.obolibrary.org/obo/MONDO_0002050
T85 21300-21303 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T86 21457-21463 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T87 21504-21517 Disease denotes hyperglycemia http://purl.obolibrary.org/obo/MONDO_0002909
T88 21558-21577 Disease denotes acute kidney injury http://purl.obolibrary.org/obo/MONDO_0002492
T89 21571-21577 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T90 21634-21640 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T91 21800-21803 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T92 21962-21965 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T93 22004-22013 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T94 22063-22084 Disease denotes klebsiella pneumoniae http://purl.obolibrary.org/obo/MONDO_0030602
T95 22097-22100 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T96 22176-22185 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T97 22274-22297 Disease denotes urinary tract infection http://purl.obolibrary.org/obo/MONDO_0001650|http://purl.obolibrary.org/obo/MONDO_0005247
T99 22288-22297 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T100 22328-22337 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T101 22355-22376 Disease denotes klebsiella pneumoniae http://purl.obolibrary.org/obo/MONDO_0030602
T102 22409-22418 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 22458-22467 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T104 22511-22520 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T105 23113-23121 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 25203-25217 Disease denotes Hypersensitive http://purl.obolibrary.org/obo/MONDO_0000605
T107 25422-25449 Disease denotes Hospital-acquired infection http://purl.obolibrary.org/obo/MONDO_0043544
T108 25440-25449 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T109 25484-25503 Disease denotes Acute kidney injury http://purl.obolibrary.org/obo/MONDO_0002492
T110 25497-25503 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T111 25550-25556 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T112 28314-28325 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T113 28518-28526 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 28707-28715 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T115 29571-29582 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T116 29677-29685 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 30501-30512 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T118 30910-30918 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T119 30996-30999 Disease denotes HAI http://purl.obolibrary.org/obo/MONDO_0043544
T120 31115-31126 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T121 31259-31267 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T122 31704-31712 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 31780-31788 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 31780-31784 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T125 31856-31864 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 31865-31877 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T127 31954-31962 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 31974-31997 Disease denotes Guillain-Barré Syndrome http://purl.obolibrary.org/obo/MONDO_0016218
T129 31999-32011 Disease denotes polyneuritis http://purl.obolibrary.org/obo/MONDO_0021718
T130 32027-32033 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T132 32250-32258 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 32277-32285 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 32585-32593 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T135 32646-32663 Disease denotes sleep disturbance http://purl.obolibrary.org/obo/MONDO_0003406
T136 33168-33177 Disease denotes analgesia http://purl.obolibrary.org/obo/MONDO_0000675
T137 33294-33302 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T138 33415-33423 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T139 33879-33887 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 34058-34066 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T141 34554-34562 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T142 35445-35453 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T143 36451-36459 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 36501-36512 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T145 36768-36779 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T146 36802-36810 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 36811-36820 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T148 36940-36948 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 37181-37183 Disease denotes KH http://purl.obolibrary.org/obo/MONDO_0016236
T150 37384-37386 Disease denotes KH http://purl.obolibrary.org/obo/MONDO_0016236

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 136-137 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T2 2770-2771 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 2917-2920 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T4 3032-3037 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T5 3482-3483 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 3884-3885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 4040-4041 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 4376-4377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 4915-4916 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 5022-5035 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T11 5268-5277 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T12 5508-5527 http://purl.obolibrary.org/obo/CL_0000623 denotes natural killer cell
T13 5528-5536 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T14 5544-5549 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T15 5544-5549 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T16 6981-6983 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T17 7036-7041 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T18 7036-7041 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T19 7379-7380 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T20 8936-8941 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T21 9122-9127 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T22 9122-9127 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T23 9122-9127 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T24 9122-9127 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T25 9143-9148 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T26 9143-9148 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T27 9230-9235 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T28 9230-9235 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T29 9245-9250 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T30 9245-9250 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T31 9527-9533 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T32 9527-9533 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T33 9527-9533 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T34 9554-9559 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T35 9554-9559 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T36 9700-9706 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T37 9700-9706 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T38 9700-9706 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T39 9959-9964 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T40 9959-9964 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T41 10048-10050 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T42 10346-10347 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T43 10378-10388 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T44 10451-10455 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T45 10872-10873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 11800-11801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 12131-12132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 12727-12732 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T49 12727-12732 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T50 13331-13336 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T51 13406-13414 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T52 13486-13490 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T53 13523-13527 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T54 13547-13551 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T55 13553-13554 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T56 13959-13960 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 14000-14002 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T58 14290-14292 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T59 15014-15015 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T60 15161-15166 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T61 15618-15620 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T62 15677-15679 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T63 15759-15763 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T64 15759-15763 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T65 15802-15808 http://purl.obolibrary.org/obo/UBERON_0003100 denotes Female
T66 16037-16038 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T67 16325-16327 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T68 16473-16475 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T69 17027-17029 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T70 17119-17121 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T71 17167-17169 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T72 17186-17188 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T73 17211-17213 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T74 17431-17436 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T75 17874-17879 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T76 17874-17879 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T77 17874-17879 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T78 17874-17879 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T79 18158-18160 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T80 18244-18249 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T81 20769-20770 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 20773-20775 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T83 21412-21417 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T84 21451-21456 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T85 21451-21456 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T86 21564-21570 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T87 21564-21570 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T88 21564-21570 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T89 22274-22287 http://purl.obolibrary.org/obo/UBERON_0001008 denotes urinary tract
T90 22315-22320 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T91 22315-22320 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T92 22445-22450 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T93 22445-22450 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T94 23200-23205 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T95 23200-23205 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T96 23222-23227 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T97 23222-23227 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T98 23808-23817 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activated
T99 23918-23929 http://purl.obolibrary.org/obo/PR_000007299 denotes Prothrombin
T100 24073-24078 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T101 24073-24078 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T102 24217-24223 http://purl.obolibrary.org/obo/CLO_0007201 denotes L 5–40
T103 24372-24377 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T104 24372-24377 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T105 25160-25162 http://purl.obolibrary.org/obo/PR_000010213 denotes MB
T106 25309-25314 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T107 25309-25314 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T108 25490-25496 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T109 25490-25496 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T110 25490-25496 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T111 25634-25637 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T112 25645-25647 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T113 25794-25797 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T114 26044-26046 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T115 26388-26390 http://purl.obolibrary.org/obo/CLO_0001547 denotes aP
T116 26556-26565 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T117 26595-26606 http://purl.obolibrary.org/obo/PR_000007299 denotes prothrombin
T118 26930-26932 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T119 28378-28379 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T120 28422-28423 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T121 30480-30481 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T122 30829-30830 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 31092-31093 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T124 31568-31569 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T125 31846-31847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T126 32777-32781 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T127 33324-33325 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 33361-33370 http://purl.obolibrary.org/obo/BFO_0000030 denotes objective
T129 33498-33508 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T130 33620-33624 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T131 33630-33631 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 35065-35068 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T133 35247-35250 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T134 35846-35847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T135 35991-35996 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T136 36013-36014 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 36054-36055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T138 36343-36352 http://purl.obolibrary.org/obo/BFO_0000030 denotes objective
T139 36480-36481 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T140 37259-37261 http://purl.obolibrary.org/obo/CLO_0003744 denotes HH
T141 37989-37999 http://purl.obolibrary.org/obo/BFO_0000030 denotes objectives
T142 38386-38387 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T143 38625-38626 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1204-1209 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T2 1225-1230 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T3 1271-1276 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T4 1298-1303 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T5 1368-1373 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T6 1554-1559 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T7 1588-1593 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T8 2157-2162 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T9 2241-2246 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T10 2293-2298 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T11 2436-2441 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T12 2557-2562 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T13 2590-2595 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T14 4399-4408 Chemical denotes indicator http://purl.obolibrary.org/obo/CHEBI_47867
T15 4814-4819 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T16 6200-6203 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T17 8786-8795 Chemical denotes endocrine http://purl.obolibrary.org/obo/CHEBI_24621
T18 9103-9109 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T19 9342-9348 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T20 9383-9392 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T21 9402-9413 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T22 9415-9430 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T23 11923-11928 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T24 11990-11995 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T25 12385-12390 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T26 12471-12476 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T27 13176-13178 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T28 13323-13328 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T29 14629-14634 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T30 14660-14665 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T31 15222-15227 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T32 18100-18106 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T33 18599-18605 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T34 18661-18666 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T35 18712-18717 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T36 18780-18785 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T37 19090-19095 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T38 19166-19171 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T39 19201-19206 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T40 21391-21396 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T41 21698-21703 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T42 21719-21724 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T43 21764-21769 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T44 21869-21874 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T45 21984-21989 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T46 22119-22124 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T47 22189-22199 Chemical denotes carbapenem http://purl.obolibrary.org/obo/CHEBI_46765
T48 22557-22567 Chemical denotes carbapenem http://purl.obolibrary.org/obo/CHEBI_46765
T49 22667-22672 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T50 22772-22777 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T51 22835-22840 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T52 22987-22992 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T53 23918-23929 Chemical denotes Prothrombin http://purl.obolibrary.org/obo/CHEBI_8583
T54 24193-24200 Chemical denotes Alanine http://purl.obolibrary.org/obo/CHEBI_16449
T55 24289-24298 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990
T56 24378-24382 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T57 24383-24391 Chemical denotes nitrogen http://purl.obolibrary.org/obo/CHEBI_25555
T58 24475-24485 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T59 24564-24572 Chemical denotes Creatine http://purl.obolibrary.org/obo/CHEBI_16919
T60 24758-24765 Chemical denotes Glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_42758
T63 24849-24855 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T65 25144-25152 Chemical denotes Creatine http://purl.obolibrary.org/obo/CHEBI_16919
T66 25602-25608 Chemical denotes Oxygen http://purl.obolibrary.org/obo/CHEBI_15379
T67 25673-25679 Chemical denotes Oxygen http://purl.obolibrary.org/obo/CHEBI_15379
T68 25733-25739 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T69 26713-26718 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T70 26808-26813 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T71 26845-26853 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T73 26919-26924 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T74 26968-26973 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T75 27081-27086 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T76 27115-27120 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T77 27365-27370 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T78 27585-27590 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T79 27674-27679 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T80 27883-27888 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T81 28863-28868 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T82 29008-29013 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T83 29101-29106 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T84 29189-29194 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T85 29275-29280 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T86 29361-29366 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T87 29935-29940 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T88 30136-30141 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T89 30632-30637 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T90 30788-30793 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T91 30960-30965 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T92 31065-31070 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T93 31145-31150 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T94 31365-31370 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T95 31417-31422 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T96 31506-31511 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T97 32946-32963 Chemical denotes psychotropic drug http://purl.obolibrary.org/obo/CHEBI_35471
T98 32959-32963 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T99 33769-33773 Chemical denotes gold http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050
T101 34301-34312 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T102 37013-37015 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T103 37177-37179 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T104 37181-37183 Chemical denotes KH http://purl.obolibrary.org/obo/CHEBI_32589
T105 37189-37191 Chemical denotes YS http://purl.obolibrary.org/obo/CHEBI_141457
T106 37259-37261 Chemical denotes HH http://purl.obolibrary.org/obo/CHEBI_74051
T107 37263-37265 Chemical denotes HL http://purl.obolibrary.org/obo/CHEBI_5729
T108 37384-37386 Chemical denotes KH http://purl.obolibrary.org/obo/CHEBI_32589
T109 37466-37468 Chemical denotes YS http://purl.obolibrary.org/obo/CHEBI_141457
T110 37474-37476 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T111 37491-37493 Chemical denotes YS http://purl.obolibrary.org/obo/CHEBI_141457
T112 37498-37500 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 49-60 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T2 229-240 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T3 724-735 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T4 2739-2750 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T5 2791-2802 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T6 3001-3021 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T7 4213-4224 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T8 4639-4650 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T9 4867-4878 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T10 5201-5218 Phenotype denotes Sleep disturbance http://purl.obolibrary.org/obo/HP_0002360
T11 5707-5729 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T12 6152-6159 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T13 6181-6191 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T14 6479-6490 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T15 7333-7354 Phenotype denotes loss of consciousness http://purl.obolibrary.org/obo/HP_0007185
T16 7624-7633 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 9521-9540 Phenotype denotes acute kidney injury http://purl.obolibrary.org/obo/HP_0001919
T18 9542-9545 Phenotype denotes AKI http://purl.obolibrary.org/obo/HP_0001919
T19 9554-9571 Phenotype denotes liver dysfunction http://purl.obolibrary.org/obo/HP_0001410
T20 9595-9608 Phenotype denotes hyperglycemia http://purl.obolibrary.org/obo/HP_0003074
T21 9650-9653 Phenotype denotes AKI http://purl.obolibrary.org/obo/HP_0001919
T22 9700-9714 Phenotype denotes Kidney Disease http://purl.obolibrary.org/obo/HP_0000112
T23 9821-9835 Phenotype denotes hypersensitive http://purl.obolibrary.org/obo/HP_0041092
T24 9959-9976 Phenotype denotes liver dysfunction http://purl.obolibrary.org/obo/HP_0001410
T25 11596-11614 Phenotype denotes sleep disturbances http://purl.obolibrary.org/obo/HP_0002360
T26 14340-14361 Phenotype denotes loss of consciousness http://purl.obolibrary.org/obo/HP_0007185
T27 16596-16620 Phenotype denotes Gastrointestinal disease http://purl.obolibrary.org/obo/HP_0011024
T28 16852-16857 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T29 16897-16902 Phenotype denotes Cough http://purl.obolibrary.org/obo/HP_0012735
T30 16941-16960 Phenotype denotes Shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T31 16999-17006 Phenotype denotes Fatigue http://purl.obolibrary.org/obo/HP_0012378
T32 17097-17104 Phenotype denotes Myalgia http://purl.obolibrary.org/obo/HP_0003326
T33 17108-17118 Phenotype denotes arthralgia http://purl.obolibrary.org/obo/HP_0002829
T34 17157-17166 Phenotype denotes Diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T35 17204-17210 Phenotype denotes Chills http://purl.obolibrary.org/obo/HP_0025143
T36 17250-17268 Phenotype denotes Nausea or Vomiting http://purl.obolibrary.org/obo/HP_0002017
T37 17304-17312 Phenotype denotes Anorexia http://purl.obolibrary.org/obo/HP_0002039
T38 17347-17355 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T39 17389-17398 Phenotype denotes Dizziness http://purl.obolibrary.org/obo/HP_0002321
T40 17431-17441 Phenotype denotes Chest pain http://purl.obolibrary.org/obo/HP_0100749
T41 17474-17486 Phenotype denotes Pharyngalgia http://purl.obolibrary.org/obo/HP_0033050
T42 17563-17574 Phenotype denotes Haemoptysis http://purl.obolibrary.org/obo/HP_0002105
T43 17605-17619 Phenotype denotes Abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T44 19447-19455 Phenotype denotes insomnia http://purl.obolibrary.org/obo/HP_0100785
T45 20849-20857 Phenotype denotes insomnia http://purl.obolibrary.org/obo/HP_0100785
T46 20973-20980 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739
T47 20999-21009 Phenotype denotes depression http://purl.obolibrary.org/obo/HP_0000716
T48 21504-21517 Phenotype denotes hyperglycemia http://purl.obolibrary.org/obo/HP_0003074
T49 21558-21577 Phenotype denotes acute kidney injury http://purl.obolibrary.org/obo/HP_0001919
T50 21994-22013 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T51 22074-22084 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T52 22166-22185 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T53 22274-22297 Phenotype denotes urinary tract infection http://purl.obolibrary.org/obo/HP_0000010
T54 22366-22376 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T55 22399-22418 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T56 22501-22520 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T57 25203-25217 Phenotype denotes Hypersensitive http://purl.obolibrary.org/obo/HP_0041092
T58 25309-25326 Phenotype denotes liver dysfunction http://purl.obolibrary.org/obo/HP_0001410
T59 25484-25503 Phenotype denotes Acute kidney injury http://purl.obolibrary.org/obo/HP_0001919
T60 28314-28325 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T61 29571-29582 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T62 30501-30512 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T63 31115-31126 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T64 31865-31877 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T65 31999-32011 Phenotype denotes polyneuritis http://purl.obolibrary.org/obo/HP_0031003
T66 32027-32033 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T67 32646-32663 Phenotype denotes sleep disturbance http://purl.obolibrary.org/obo/HP_0002360
T68 33206-33226 Phenotype denotes breathing difficulty http://purl.obolibrary.org/obo/HP_0002094
T69 36501-36512 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T70 36768-36779 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 5-10 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T2 185-190 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T3 271-276 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T4 360-365 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T5 451-456 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T6 536-541 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T7 693-698 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T8 933-938 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T9 975-980 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T10 1022-1027 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T11 1198-1203 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T12 1219-1224 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T13 1265-1270 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T14 1292-1297 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T15 1548-1553 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T16 1582-1587 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T17 2151-2156 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T18 2235-2240 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T19 2287-2292 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T20 2430-2435 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T21 2551-2556 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T22 2584-2589 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T23 2676-2681 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T24 4906-4911 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T25 5007-5017 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T26 5036-5047 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T27 5128-5133 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T28 5201-5206 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T29 5238-5263 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T30 5278-5290 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T31 5372-5389 http://purl.obolibrary.org/obo/GO_0007623 denotes circadian rhythms
T32 5459-5464 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T33 5508-5536 http://purl.obolibrary.org/obo/GO_0030101 denotes natural killer cell activity
T34 5592-5608 http://purl.obolibrary.org/obo/GO_0007623 denotes circadian rhythm
T35 5602-5608 http://purl.obolibrary.org/obo/GO_0048511 denotes rhythm
T36 5612-5617 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T37 5627-5632 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T38 5662-5667 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T39 5864-5869 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T40 5920-5925 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T41 6277-6282 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T42 6448-6453 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T43 8030-8035 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T44 8075-8080 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T45 9306-9317 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T46 9358-9374 http://purl.obolibrary.org/obo/GO_0042310 denotes vasoconstrictive
T47 9821-9835 http://purl.obolibrary.org/obo/GO_0002524 denotes hypersensitive
T48 10279-10284 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T49 10318-10323 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T50 10485-10490 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T51 10500-10505 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T52 10597-10602 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T53 10811-10816 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T54 10914-10919 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T55 10927-10932 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T56 10997-11002 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T57 11114-11119 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T58 11178-11183 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T59 11236-11241 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T60 11367-11372 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T61 11523-11528 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T62 11538-11543 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T63 11554-11559 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T64 11578-11583 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T65 11596-11601 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T66 11623-11628 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T67 11751-11756 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T68 11839-11844 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T69 11917-11922 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T70 11984-11989 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T71 12246-12251 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T72 12379-12384 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T73 12465-12470 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T74 14432-14437 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T75 14623-14628 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T76 14654-14659 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T77 15498-15503 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T78 15518-15523 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T79 18462-18467 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T80 18477-18482 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T81 18655-18660 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T82 18706-18711 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T83 18739-18744 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T84 18774-18779 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T85 19084-19089 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T86 19160-19165 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T87 19195-19200 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T88 19311-19316 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T89 19536-19541 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T90 19614-19619 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T91 19634-19639 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T92 20685-20690 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T93 21080-21085 http://purl.obolibrary.org/obo/GO_0030431 denotes Sleep
T94 21125-21130 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T95 21193-21198 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T96 21212-21217 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T97 21692-21697 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T98 21713-21718 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T99 21758-21763 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T100 21863-21868 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T101 21978-21983 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T102 22113-22118 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T103 22661-22666 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T104 22766-22771 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T105 22829-22834 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T106 22981-22986 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T107 23157-23162 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T108 23177-23182 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T109 23782-23793 http://purl.obolibrary.org/obo/GO_0050817 denotes Coagulation
T110 25203-25217 http://purl.obolibrary.org/obo/GO_0002524 denotes Hypersensitive
T111 26062-26078 http://purl.obolibrary.org/obo/GO_0042310 denotes Vasoconstrictive
T112 26432-26437 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T113 26447-26452 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T114 26707-26712 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T115 26802-26807 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T116 26913-26918 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T117 26962-26967 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T118 27075-27080 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T119 27109-27114 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T120 27359-27364 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T121 27579-27584 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T122 27668-27673 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T123 27877-27882 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T124 28283-28288 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T125 28539-28544 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T126 28554-28559 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T127 28728-28733 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T128 28743-28748 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T129 28857-28862 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T130 29002-29007 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T131 29095-29100 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T132 29183-29188 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T133 29269-29274 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T134 29355-29360 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T135 29536-29541 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T136 29788-29793 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T137 29850-29855 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T138 30130-30135 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T139 30151-30156 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T140 30431-30436 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T141 30626-30631 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T142 30782-30787 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T143 30856-30861 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T144 30954-30959 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T145 31059-31064 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T146 31139-31144 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T147 31278-31283 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T148 31359-31364 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T149 31411-31416 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T150 31500-31505 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T151 32168-32173 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T152 32296-32301 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T153 32349-32354 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T154 32539-32544 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T155 32646-32651 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T156 33206-33215 http://purl.obolibrary.org/obo/GO_0007585 denotes breathing
T157 33263-33268 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T158 33381-33386 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T159 33552-33557 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T160 33805-33810 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T161 33848-33853 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T162 34240-34245 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T163 34361-34366 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T164 34588-34593 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T165 34700-34705 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T166 34792-34797 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T167 34984-34989 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T168 35202-35207 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T169 35414-35419 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T170 35617-35622 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T171 35672-35677 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T172 36353-36358 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T173 36420-36425 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T174 36720-36725 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-135 Sentence denotes Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19:
T2 136-164 Sentence denotes A retrospective cohort study
T3 166-176 Sentence denotes Highlights
T4 177-262 Sentence denotes • Poor sleep is associated with slow recovery from lymphopenia in COVID-19 patients.
T5 263-351 Sentence denotes • Poor sleep is associated with increased requirement of ICU care in COVID-19 patients.
T6 352-440 Sentence denotes • Poor sleep is associated with prolonged length of hospital stay in COVID-19 patients.
T7 442-450 Sentence denotes Abstract
T8 451-511 Sentence denotes Sleep is known to play an important role in immune function.
T9 512-601 Sentence denotes However, the effects of sleep quality during hospitalization for COVID-19 remain unclear.
T10 602-910 Sentence denotes This retrospective, single-center cohort study was conducted to investigate the effects of sleep quality on recovery from lymphopenia and clinical outcomes in hospitalized patients with laboratory-confirmed COVID-19 admitted to the West District of Wuhan Union Hospital between January 25 and March 15, 2020.
T11 911-1036 Sentence denotes The Richards-Campbell sleep questionnaire (RCSQ) and Pittsburgh Sleep Quality Index (PSQI) were used to assess sleep quality.
T12 1037-1231 Sentence denotes The epidemiological, demographic, clinical, laboratory, treatment, and outcome data were collected from electronic medical records and compared between the good-sleep group and poor-sleep group.
T13 1232-1333 Sentence denotes In all, 135 patients (60 in good-sleep group and 75 in poor-sleep group) were included in this study.
T14 1334-1512 Sentence denotes There were no significant between-group differences regarding demographic and baseline characteristics, as well as laboratory parameters upon admission and in-hospital treatment.
T15 1513-2116 Sentence denotes Compared with patients in the good-sleep group, patients in the poor-sleep group had lower absolute lymphocyte count (ALC) (day 14: median, 1.10 vs 1.32, P = 0.0055; day 21: median, 1.18 vs 1.48, P = 0.0034) and its reduced recovery rate (day 14: median, 56.91 vs 69.40, P = 0.0255; day 21: median, 61.40 vs 111.47, P = 0.0003), as well as increased neutrophil-to-lymphocyte ratio (NLR; day 14: median, 3.17 vs 2.44, P = 0.0284; day 21: median, 2.73 vs 2.23, P = 0.0092) and its associated deterioration rate (day 14: median, −39.65 vs −61.09, P = 0.0155; day 21: median, −51.40% vs −75.43, P = 0.0003).
T16 2117-2265 Sentence denotes Nine [12.0%] patients in the poor-sleep group required ICU care (P = 0.0151); meanwhile, none of the patients in good-sleep group required ICU care.
T17 2266-2442 Sentence denotes Patients in the poor-sleep group had increased duration of hospital stay (33.0 [23.0–47.0] days vs 25.0 [20.5–36.5] days, P = 0.0116) compared to those in the good-sleep group.
T18 2443-2655 Sentence denotes An increased incidence of hospital-acquired infection (seven [9.3%] vs one [1.7%]) was observed in the poor-sleep group compared to the good-sleep group; however, this difference was not significant (P = 0.1316).
T19 2656-2838 Sentence denotes In conclusion, poor sleep quality during hospitalization in COVID-19 patients with lymphopenia is associated with a slow recovery from lymphopenia and an increased need for ICU care.
T20 2840-2855 Sentence denotes 1 Introduction
T21 2856-2946 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread worldwide.
T22 2947-3152 Sentence denotes COVID-19 is highly contagious and can result in acute respiratory distress, multiple organ failure, or death in severe cases (Huang et al., 2020a, Wang et al., 2020, Yang et al., 2020, Zhang et al., 2020).
T23 3153-3338 Sentence denotes The reported mortality rate of COVID-19 is lower than that of severe acute respiratory syndrome (SARS) (Donnelly et al., 2003), or Middle East respiratory syndrome (MERS) (Ahmed, 2017).
T24 3339-3654 Sentence denotes However, the number of patients needing urgent critical care is remarkably larger than previous outbreaks of SARS or MERS, which could lead to a critical shortage of intensive care unit (ICU) beds and specialized medical and nursing personnel, and, consequently, result in the collapse of local health care systems.
T25 3655-3842 Sentence denotes Thus, timely and appropriate dynamic monitoring and treatment for non-ICU inpatients is urgent and necessary to reduce the risk of patients becoming critically ill and requiring ICU care.
T26 3843-3971 Sentence denotes Patients with COVID-19 typically present a decrease in absolute lymphocyte count (ALC) (Huang et al., 2020a, Wang et al., 2020).
T27 3972-4204 Sentence denotes The dynamic profile of total circulating lymphocytes indicated that a continuous and sustained decrease in the ALC is closely associated with disease aggravation and death in COVID-19 patients (Wang et al., 2020, Zhou et al., 2020).
T28 4205-4303 Sentence denotes Indeed, lymphopenia was associated with increased disease severity in COVID-19 (Tan et al., 2020).
T29 4304-4586 Sentence denotes In addition, the neutrophil-to-lymphocyte ratio (NLR) can also serve as a simple complementary indicator to predict clinical severity and prognosis, and is an independent risk factor for mortality in patients with COVID-19 (Lagunas-Rangel, 2020, Qin et al., 2020, Liu et al., 2020).
T30 4587-4792 Sentence denotes These studies indicate that promoting recovery from lymphopenia and slowing the deterioration based on an increased NLR may reduce the need for ICU care and improve the prognosis of patients with COVID-19.
T31 4793-4905 Sentence denotes To date, no specific drugs have been shown to be effective in alleviating lymphopenia in patients with COVID-19.
T32 4906-5200 Sentence denotes Sleep is a physiological and behavioral process required for survival and plays an important role in metabolism and immune system homeostasis (Besedovsky et al., 2019, Haspel et al., 2020, Mukherjee et al., 2015); indeed, sleep and immunity are bidirectionally linked (Besedovsky et al., 2019).
T33 5201-5447 Sentence denotes Sleep disturbance impairs innate and adaptive immune responses and activates inflammation, with an increase in circulating inflammatory cytokines due to disruption of the circadian rhythms (Haack et al., 2007, Irwin, 2015, Vgontzas et al., 2004).
T34 5448-5573 Sentence denotes Short-term sleep deprivation is associated with compromised natural killer cell activity in the blood (Fondell et al., 2011).
T35 5574-5812 Sentence denotes Disruption of the circadian rhythm of sleep, shorter sleep duration, or poor quality of sleep could increase susceptibility to upper respiratory infections (Cohen et al., 2009, Loef et al., 2019, Patel et al., 2012, Prather et al., 2015).
T36 5813-5919 Sentence denotes In fact, septic patients with frequently disrupted sleep have higher mortality rates (Huang et al., 2014).
T37 5920-6218 Sentence denotes Sleep impairment occurs frequent in patients with COVID-19 (Liguori et al., 2020), which may be due to isolated environment without family member’ companion, physical discomfort caused by the illness, or psychological factor (fear, anxiety, helplessness and/or depression, etc.) (Guo et al., 2020).
T38 6219-6382 Sentence denotes However, there are currently no reports of the effects of sleep quality during hospitalization on immune function recovery and prognosis in patients with COVID-19.
T39 6383-6594 Sentence denotes In tour study, we aimed to describe the effects of self-reported sleep quality on recovery from lymphopenia, deterioration based on an increased NLR, and clinical outcomes in hospitalized patients with COVID-19.
T40 6596-6620 Sentence denotes 2 Materials and methods
T41 6622-6656 Sentence denotes 2.1 Study design and participants
T42 6657-6921 Sentence denotes For this single-center retrospective study, 449 hospitalized patients with laboratory confirmed COVID-19 admitted to the West District of Wuhan Union Hospital between January 25 and March 15, 2020 were screened using the following inclusion and exclusion criteria.
T43 6922-7102 Sentence denotes The inclusion criteria included: (1) patients aged between 18 and 80 years; and (2) absolute counts of peripheral blood lymphocytes < 1.1 × 109/L within 24 h of hospital admission.
T44 7103-7378 Sentence denotes The exclusion criteria included: (1) duration of hospital stay < 14 days or death during hospitalization; (2) pregnant or lactating women; (3) deterioration of the condition requiring ICU care within 14 days of admission; and (4) loss of consciousness during hospitalization.
T45 7379-7463 Sentence denotes A total of 153 patients met these criteria and were included in the study (Fig. 1 ).
T46 7464-7733 Sentence denotes The diagnosis, clinical classification, treatment, and discharge criteria of COVID-19 were based on the “Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (6th edition)” issued by the National Health and Family Planning Commission of China (NHPFC, 2020).
T47 7734-7836 Sentence denotes COVID-19 was confirmed by real-time RT-PCR for throat-swab specimens from the upper respiratory tract.
T48 7837-7891 Sentence denotes All the included patients had recovered from COVID-19.
T49 7892-7918 Sentence denotes Fig. 1 Study flow diagram.
T50 7919-8095 Sentence denotes ALC, absolute lymphocyte count; COVID-19, coronavirus disease-2019; ICU, intensive care unit; PSQI, Pittsburgh Sleep Quality Index; RCSQ, Richards-Campbell sleep questionnaire.
T51 8096-8251 Sentence denotes The study was approved by the Ethics Committee of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (Permission number:
T52 8252-8258 Sentence denotes 0173).
T53 8259-8370 Sentence denotes Informed consent for this retrospective study was waived due to the rapid emergence of this infectious disease.
T54 8372-8392 Sentence denotes 2.2 Data collection
T55 8393-8550 Sentence denotes We reviewed the hospital's electronic medical records, nurse records, laboratory findings, and imaging examinations for all patients with confirmed COVID-19.
T56 8551-8592 Sentence denotes All data were checked by two researchers.
T57 8593-9649 Sentence denotes We collected data on age, sex, body mass index, education levels, marital status, comorbidities (chronic respiratory disease, cardiovascular and cerebrovascular diseases, and gastrointestinal, endocrine, urologic, and nervous system diseases), current smoking status, time from symptom onset to admission, signs and symptoms at disease onset, chest imaging abnormalities (unilateral or bilateral distribution of patchy shadows or ground glass opacity), vital signs on admission (respiratory rate, percutaneous oxygen saturation, heart rate, systolic blood pressure, and body temperature), laboratory parameters within 24 h of admission (blood routine, blood biochemistry and electrolytes, cardiac biomarkers, and coagulation parameters), treatment (oxygen therapy, vasoconstrictive agents, antiviral therapy, antibiotics, corticosteroids, immunoglobulin, and immunoregulatory therapy), and complications during hospitalization (acute kidney injury (AKI), acute liver dysfunction, acute cardiac injury, hyperglycemia, and hospital-acquired infection (HAI)).
T58 9650-9715 Sentence denotes AKI was identified based on the definition in the Kidney Disease:
T59 9716-9766 Sentence denotes Improving Global Outcomes statement (KDIGO, 2012).
T60 9767-9952 Sentence denotes Cardiac injury was diagnosed when the levels of serum hypersensitive cardiac troponin I exceeded the upper limit of normal (ULN), measured in the laboratory of the Wuhan Union Hospital.
T61 9953-10009 Sentence denotes Acute liver dysfunction was defined as an ALT ≥ 1 × ULN.
T62 10010-10078 Sentence denotes HAI was defined as infection acquired>48 h after hospital admission.
T63 10079-10272 Sentence denotes For patient(s) with deterioration of the condition requiring ICU care, the subsequent data regarding laboratory parameters, treatment, and complications were not included in the final analysis.
T64 10274-10295 Sentence denotes 2.3 Sleep assessment
T65 10296-10499 Sentence denotes The Richards-Campbell sleep questionnaire (RCSQ), a widely used subjective survey instrument (Nagatomo et al., 2020, Richards et al., 2000, Simons et al., 2018), was administered to assess sleep quality.
T66 10500-10584 Sentence denotes Sleep assessment was performed by telephone within 30 days after hospital admission.
T67 10585-10825 Sentence denotes The overall sleep quality was assessed within the first week (score one), second week (score two), and third week (score three) after admission using the RCSQ, since not all patients were able to accurately assess their daily sleep quality.
T68 10826-11011 Sentence denotes The RCSQ assesses the following five items on a 0–100 mm visual analog scale: perceived sleep depth, sleep latency, frequency of awakenings, latency after awakenings, and sleep quality.
T69 11012-11128 Sentence denotes The overall RCSQ score is the average value of these five items, with higher scores indicating better sleep quality.
T70 11129-11203 Sentence denotes Self-reported factors associated with disruptive sleep were also recorded.
T71 11204-11469 Sentence denotes After assessment with the RCSQ, sleep quality within two or three weeks after hospital admission was further confirmed using the Chinese version of the Pittsburgh Sleep Quality Index (PSQI), which is reliable and valid for the Chinese population (Liu et al., 1996).
T72 11470-11665 Sentence denotes The PSQI includes seven component scores: subjective sleep quality, sleep duration, sleep latency, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
T73 11666-11872 Sentence denotes The sum of the seven component scores (each ranging from 0 to 3) provides the global sleep quality score (ranging from 0 to 21), with a score greater than 7 indicating poor sleep quality (Liu et al., 1996).
T74 11873-12042 Sentence denotes Patients were divided into two groups: good-sleep group (at least two RCSQ scores ≥ 70, and PSQI ≤ 7) and poor-sleep group (at least two RCSQ scores ≤ 50, and PSQI > 7).
T75 12043-12477 Sentence denotes Patients with deterioration of their health condition requiring ICU care, or those with a duration of hospital stay < 21 days were assigned to one of the two groups based on the overall quality of their sleep within the first two weeks after hospital admission: patients with two RCSQ scores ≥ 70 and PSQI ≤ 7 were assigned to the good-sleep group and those with one RCSQ score ≤ 50 and PSQI > 7 were assigned to the poor-sleep group.
T76 12479-12492 Sentence denotes 2.4 Outcomes
T77 12493-12692 Sentence denotes The primary outcomes were: (1) recovery rate based on ALC and deterioration based on an increased NLR on day 7, 14, and 21 after admission; (2) need for ICU care within 14 days of hospital admission.
T78 12693-12822 Sentence denotes The absolute counts of peripheral blood lymphocytes and neutrophils within 24 h of hospital admission were set as baseline value.
T79 12823-12971 Sentence denotes The formula for the recovery percentage or deteriorative percentage is described as:ALCorNLRday7,day14orday21--ALCorNLRbaselineALCorNLRbaseline×100%
T80 12972-13048 Sentence denotes The secondary outcomes were: (1) HAI; and (2) total length of hospital stay.
T81 13050-13075 Sentence denotes 2.5 Statistical analysis
T82 13076-13127 Sentence denotes Categorical variables were described as number (%).
T83 13128-13269 Sentence denotes Continuous variables were described using mean (SD) if they were normally distributed, or median (interquartile range, IQR) if they were not.
T84 13270-13420 Sentence denotes Continuous variables were compared using independent group t tests when the data were normally distributed; otherwise, the Mann-Whitney test was used.
T85 13421-13552 Sentence denotes Proportions for categorical variables were compared using the χ2 test, Yates’ continuity corrected χ2 test, or Fisher’s exact test.
T86 13553-13621 Sentence denotes A two-sided P value < 0.05 was considered statistically significant.
T87 13622-13713 Sentence denotes The data collected were all analyzed using SPSS version 20.0 software (SPSS, Tokyo, Japan).
T88 13715-13725 Sentence denotes 3 Results
T89 13727-13740 Sentence denotes 3.1 Patients
T90 13741-13877 Sentence denotes In all, 449 patients admitted to West District of Wuhan Union Hospital between January 25 and March 15, 2020 were included in the study.
T91 13878-13927 Sentence denotes Subsequently, we excluded the following patients:
T92 13928-14570 Sentence denotes 186 patients that did not have a decreased ALC upon hospital admission, 35 patients without relevant information in their medical records, 25 patients with duration of hospital stay less than 14 days or death during hospitalization, 25 patients with deteriorated condition requiring ICU care within 14 days after hospital admission, 12 patients aged > 80 years, 11 pregnant or lactating women, two patients with loss of consciousness during hospitalization, seven patients who were uncertain about their sleep quality, seven patients with at least two RCSQ scores between 50 and 70, and four patients with inconsistency between RCSQ and PSQI.
T93 14571-14698 Sentence denotes Therefore, we included 135 patients (60 in the good-sleep group and 75 in the poor-sleep group) in the final analysis (Fig. 1).
T94 14700-14817 Sentence denotes 3.2 Demographic and baseline characteristics, as well as laboratory parameters upon hospital admission and treatment
T95 14818-14920 Sentence denotes The median age of patients was 63 years (IQR, 55–69 years), and 57.8% of patients were men (Table 1 ).
T96 14921-15013 Sentence denotes The median interval time from symptom onset to admission was 11.0 days (IQR, 9.0–13.5 days).
T97 15014-15187 Sentence denotes A total of 83 (61.5%) patients had comorbidities, and 134 (99.3%) patients had bilateral distribution of patchy shadows or ground glass opacity on chest x-ray or CT imaging.
T98 15188-15399 Sentence denotes There were no significant between-group differences in demographic and baseline characteristics (Table 1), as well as laboratory parameters upon hospital admission and treatment during hospitalization (Table 3).
T99 15400-15476 Sentence denotes Table 1 Demographics and baseline characteristics of patients with COVID-19.
T100 15477-15540 Sentence denotes Total (n = 135) Good sleep (n = 60) Poor sleep (n = 75) P value
T101 15541-15605 Sentence denotes Age, median (IQR), years 63 (55–69) 61 (51–68) 64 (56–70) 0.1126
T102 15606-15653 Sentence denotes  < 50 years 22 (16.3) 14 (23.3) 9 (12.0) 0.0818
T103 15654-15703 Sentence denotes  50–70 years 83 (61.5) 36 (60.0) 46 (61.3) 0.8747
T104 15704-15752 Sentence denotes  ≥ 70 years 30 (22.2) 10 (16.7) 20 (26.7) 0.1649
T105 15753-15757 Sentence denotes Sex:
T106 15758-15800 Sentence denotes  Male 78 (57.8) 40 (66.7) 38 (50.7) 0.0614
T107 15801-15838 Sentence denotes  Female 57 (42.2) 20 (33.3) 37 (49.3)
T108 15839-15921 Sentence denotes BMI, median (IQR), kg/m2 23.9 (22.3–25.6) 23.8 (22.5–25.3) 24.2 (22.0–25.7) 0.7886
T109 15922-15937 Sentence denotes Marital status:
T110 15938-15984 Sentence denotes  Married 129 (95.6) 57 (95.0) 72 (96.0) 0.7794
T111 15985-16026 Sentence denotes  Unmarried 3 (2.2) 2 (3.3) 1 (1.3) 0.8447
T112 16027-16076 Sentence denotes  Death of a spouse 3 (2.2) 1 (1.7) 2 (2.7) 0.8447
T113 16077-16093 Sentence denotes Education level:
T114 16094-16145 Sentence denotes  ≤ High school 96 (71.1) 39 (65.0) 57 (76.0) 0.1612
T115 16146-16205 Sentence denotes  University or college 32 (23.7) 17 (28.3) 15 (20.0) 0.2579
T116 16206-16254 Sentence denotes  Master or doctor 7 (5.2) 4 (6.7) 3 (4.0) 0.4875
T117 16255-16299 Sentence denotes Current smoking 4 (3.0) 0 (0) 4 (5.3) 0.1918
T118 16300-16314 Sentence denotes Comorbidities:
T119 16315-16351 Sentence denotes 83 (61.5) 34 (56.7) 49 (65.3) 0.3038
T120 16352-16433 Sentence denotes  Cardiovascular and cerebrovascular diseases 42 (31.1) 19 (31.7) 23 (30.7) 0.9008
T121 16434-16489 Sentence denotes  Endocrine disease 38 (28.1) 16 (26.7) 22 (29.3) 0.7321
T122 16490-16534 Sentence denotes  Malignancy 13 (9.6) 4 (6.7) 9 (12.0) 0.2966
T123 16535-16594 Sentence denotes  Chronic respiratory disease 6 (4.4) 1 (1.7) 5 (6.7) 0.3268
T124 16595-16651 Sentence denotes  Gastrointestinal disease 4 (3.0) 1 (1.7) 3 (4.0) 0.7766
T125 16652-16699 Sentence denotes  Urologic diseases 2 (1.5) 0 (0) 2 (2.7) 0.5025
T126 16700-16813 Sentence denotes Onset of symptom to hospital admission, median (IQR), days 11.0 (9.0–13.5) 11.0 (9.0–15.0) 11.0 (8.5–13.0) 0.5954
T127 16814-16850 Sentence denotes Signs and symptoms at disease onset:
T128 16851-16895 Sentence denotes  Fever 123 (91.1) 53 (88.3) 70 (93.3) 0.3104
T129 16896-16939 Sentence denotes  Cough 92 (68.1) 38 (63.3) 54 (72.0) 0.2828
T130 16940-16997 Sentence denotes  Shortness of breath 75 (55.6) 31 (51.7) 44 (58.7) 0.4160
T131 16998-17043 Sentence denotes  Fatigue 68 (50.4) 32 (53.3) 36 (48.0) 0.5380
T132 17044-17095 Sentence denotes  Expectoration 37 (27.4) 14 (23.3) 23 (30.7) 0.3425
T133 17096-17155 Sentence denotes  Myalgia or arthralgia 34 (25.2) 15 (25.0) 19 (25.3) 0.9646
T134 17156-17202 Sentence denotes  Diarrhoea 18 (13.3) 7 (11.7) 11 (14.7) 0.6104
T135 17203-17248 Sentence denotes  Chills 18 (13.3) 8 (13.3) 10 (13.3) > 0.9999
T136 17249-17302 Sentence denotes  Nausea or Vomiting 15 (11.1) 9 (15.0) 6 (8.0) 0.1984
T137 17303-17345 Sentence denotes  Anorexia 12 (8.9) 7 (11.7) 5 (6.7) 0.3104
T138 17346-17387 Sentence denotes  Headache 10 (7.4) 5 (8.3) 5 (6.7) 0.9707
T139 17388-17429 Sentence denotes  Dizziness 5 (3.7) 2 (3.3) 3 (4.0) 0.7989
T140 17430-17472 Sentence denotes  Chest pain 5 (3.7) 2 (3.3) 3 (4.0) 0.7989
T141 17473-17515 Sentence denotes  Pharyngalgia 3 (2.2) 3 (5.0) 0 (0) 0.1704
T142 17516-17561 Sentence denotes  Rhinorrhoea 2 (1.5) 1 (1.7) 1 (1.3) > 0.9999
T143 17562-17603 Sentence denotes  Haemoptysis 2 (1.5) 2 (3.3) 0 (0) 0.1957
T144 17604-17648 Sentence denotes  Abdominal pain 2 (1.5) 2 (3.3) 0 (0) 0.1957
T145 17649-17674 Sentence denotes Vital signs on admission:
T146 17675-17766 Sentence denotes  Body tempreture, median (IQR), ℃ 36.9 (36.5–38.0) 36.9 (36.6–38.0) 36.8 (36.5–37.9) 0.4967
T147 17767-17872 Sentence denotes  Systolic pressure, median (IQR), mmHg 131.0 (120.0–143.0) 131.5 (117.5–145.0) 131.0 (120.0–142.5) 0.5040
T148 17873-17975 Sentence denotes  Heart rate, median (IQR), beat per minute 85.0 (75.5–100.0) 80.5 (74.5–99.0) 87.0 (77.5–100.5) 0.2444
T149 17976-18085 Sentence denotes  Respiratory rate, median (IQR), breaths per minute 20.0 (20.0–24.5) 20.0 (20.0–24.0) 21.0 (20.0–25.0) 0.2136
T150 18086-18175 Sentence denotes  Percutaneous oxygen saturation, median (IQR), %† 95 (92–96) 95 (91–96) 94 (92–96) 0.9816
T151 18176-18270 Sentence denotes Bilateral distribution of patchy shadows or ground glass opacity on chest x-ray or CT imaging:
T152 18271-18308 Sentence denotes 134 (99.3) 59 (98.3) 75 (100%) 0.2618
T153 18309-18366 Sentence denotes Values are numbers (percentages) unless stated otherwise.
T154 18367-18418 Sentence denotes Abbreviations: IQR, interquartile range; n, number.
T155 18419-18492 Sentence denotes P values indicate differences between good-sleep and poor-sleep patients.
T156 18493-18543 Sentence denotes P < 0.05 was considered statistically significant.
T157 18544-18718 Sentence denotes †Data were missing for the measurement of percutaneous oxygen saturation in eight patients (13.3%) of the good-sleep group, and nine patients (12.0%) of the poor-sleep group.
T158 18720-18752 Sentence denotes 3.3 Self-reported sleep quality
T159 18753-19107 Sentence denotes Patients in the poor-sleep group had lower RCSQ scores in the first week (median, 40.0 [IQR, 30.0–50.0] vs 75.0 [IQR, 70.0–82.0], P < 0.0001), second week (median, 45.0 [IQR, 40.0–50.0] vs 80.0 [IQR, 75.5–86.0], P < 0.0001) and third week (median, 45.0 [IQR, 40.0–50.5] vs 80.0 [IQR, 75.0–88.0], P < 0.0001) than those in the good-sleep group (Table 2 ).
T160 19108-19273 Sentence denotes The PSQI scores were higher in patients in the poor-sleep group than those in the good-sleep group (median, 12.0 [IQR, 11.0–14.0] vs 5.0 [IQR, 4.0–6.0], P < 0.0001).
T161 19274-19527 Sentence denotes Among the etiological causes of poor-sleep during hospitalization, these included environmental factors, psychosocial factors, discomfort caused by the illness, and chronic insomnia for 85.3%, 60.0%, 56.0%, and 32.0% of patients, respectively (Table 2).
T162 19528-19587 Sentence denotes Table 2 Sleep quality assessment in patients with COVID-19.
T163 19588-19608 Sentence denotes Median (IQR) P value
T164 19609-19648 Sentence denotes Good sleep (n = 60) Poor sleep (n = 75)
T165 19649-19692 Sentence denotes RCSQ scores in the first week, median (IQR)
T166 19693-19744 Sentence denotes All ages 75.0 (70.0–82.0) 40.0 (30.0–50.0) < 0.0001
T167 19745-19799 Sentence denotes  < 50 years 76.0 (71.0–84.0) 44.5 (40.0–47.5) < 0.0001
T168 19800-19855 Sentence denotes  50–70 years 75.0 (70.0–80.5) 40.0 (30.0–50.0) < 0.0001
T169 19856-19910 Sentence denotes  ≥ 70 years 78.5 (72.0–80.0) 45.0 (32.5–50.0) < 0.0001
T170 19911-19955 Sentence denotes RCSQ scores in the second week, median (IQR)
T171 19956-20007 Sentence denotes All ages 80.0 (75.5–86.0) 45.0 (40.0–50.0) < 0.0001
T172 20008-20062 Sentence denotes  < 50 years 86.0 (76.0–87.0) 46.0 (42.5–50.0) < 0.0001
T173 20063-20118 Sentence denotes  50–70 years 80.0 (75.0–85.0) 45.0 (40.0–50.0) < 0.0001
T174 20119-20173 Sentence denotes  ≥ 70 years 78.5 (76.0–82.0) 44.0 (35.0–50.0) < 0.0001
T175 20174-20217 Sentence denotes RCSQ scores in the third week, median (IQR)
T176 20218-20270 Sentence denotes  All ages 80.0 (75.0–88.0) 45.0 (40.0–50.5) < 0.0001
T177 20271-20323 Sentence denotes  < 50 years 80.0 (75.0–89.0) 51.5 (45.0–60.0) 0.0002
T178 20324-20379 Sentence denotes  50–70 years 81.0 (75.0–89.0) 45.0 (40.0–55.0) < 0.0001
T179 20380-20434 Sentence denotes  ≥ 70 years 80.0 (75.0–82.0) 45.0 (40.0–50.0) < 0.0001
T180 20435-20460 Sentence denotes PSQI scores, median (IQR)
T181 20461-20509 Sentence denotes All ages 5.0 (4.0–6.0) 12.0 (11.0–14.0) < 0.0001
T182 20510-20561 Sentence denotes  < 50 years 6.0 (4.0–6.0) 12.0 (10.5–15.0) < 0.0001
T183 20562-20614 Sentence denotes  50–70 years 5.0 (4.5–6.0) 12.0 (11.0–13.0) < 0.0001
T184 20615-20666 Sentence denotes  ≥ 70 years 5.0 (4.0–7.0) 13.0 (12.0–15.0) < 0.0001
T185 20667-20698 Sentence denotes Factors affecting sleep quality
T186 20699-20741 Sentence denotes  Environmental factor, n (%) – 61 (85.3) –
T187 20742-20784 Sentence denotes  Psychosocial factor, n (%)a – 45 (60.0) –
T188 20785-20839 Sentence denotes  Discomfort caused by the illness, n (%) – 42 (56.0) –
T189 20840-20878 Sentence denotes  Chronic insomnia, n (%) – 24 (32.0) –
T190 20879-21010 Sentence denotes Values are median (IQR [range]) unless stated otherwise. aPsychological factors include fear, anxiety, helplessness and depression.
T191 21011-21145 Sentence denotes Abbreviations: IQR, interquartile range; n, number; PSQI, Pittsburgh Sleep Quality Index; RCSQ, Richards Campbell sleep questionnaire.
T192 21146-21227 Sentence denotes P values indicate differences between the good-sleep and the poor-sleep patients.
T193 21228-21278 Sentence denotes P < 0.05 was considered statistically significant.
T194 21280-21334 Sentence denotes 3.4 Complications, HAI, and duration of hospital stay
T195 21335-21736 Sentence denotes During hospitalization, there were no important between-group differences in organ function damage, including acute liver injury (47 [62.7%] vs 37 [61.7%], P = 0.9052), hyperglycemia (33 [44.0%] vs 31 [51.7%], P = 0.3754), acute kidney injury (three [4.0%] vs 0 [0%], P = 0.3275), and acute cardiac injury (two [2.7%] vs one [1.7%], P = 0.8447) in the good-sleep group and poor-sleep group (Table 3 ).
T196 21737-21944 Sentence denotes Patients in the poor-sleep group had an increased incidence of HAI (seven [9.3%] vs one [1.7%]) compared to those in the good-sleep group; however, this difference was not significant (P = 0.1316) (Table 3).
T197 21945-22085 Sentence denotes One patient with HAI in the good-sleep group had pulmonary infection of extended-spectrum β-lactamase (EBSL)-positive klebsiella pneumoniae.
T198 22086-22602 Sentence denotes Meanwhile, HAI in the poor-sleep group included the following: two patients had pulmonary infection of carbapenem-resistant Acinetobacter Baumanii and Candida tropicalis, two patients had urinary tract infection, one patient had blood stream infection of EBSL-positive klebsiella pneumoniae, one patient had both pulmonary infection of Candida tropicalis and blood stream infection of bacillus, and one patient had pulmonary infection of Stenotrophomonas maltophilia and carbapenem-resistant Acinetobacter baumannii.
T199 22603-22794 Sentence denotes The health condition of nine [12.0%] patients in the poor-sleep group deteriorated and required ICU care (P = 0.0151); meanwhile, none of the patients in the good-sleep group needed ICU care.
T200 22795-22993 Sentence denotes In addition, patients in the poor-sleep group had an increased hospital stay (median, 33.0 [IQR, 23.0–47.0] days vs 25.0 [IQR, 20.5–36.5] days, P = 0.0116) compared to those in the good-sleep group.
T201 22994-23122 Sentence denotes Table 3 Laboratory parameters on hospital admission as well as complications, treatments and outcomes of patients with COVID-19.
T202 23123-23199 Sentence denotes Normal range Total (n = 135) Good-sleep (n = 60) Poor-sleep (n = 75) P value
T203 23200-23214 Sentence denotes Blood routine:
T204 23215-23309 Sentence denotes  White blood count, ×109/L 3.50–9.50 5.36 (4.16–7.18) 6.06 (4.77–7.57) 5.16 (4.09–6.78) 0.1260
T205 23310-23403 Sentence denotes  Neutrophil count, ×109/L 1.80–6.30 4.23 (2.98–5.99) 4.60 (3.30–6.61) 3.92 (2.92–5.54) 0.1700
T206 23404-23497 Sentence denotes  Neutrophil percentage, % 40.0–75.0 78.9 (72.1–86.7) 79.7 (73.6–86.9) 76.5 (71.9–85.9) 0.1515
T207 23498-23591 Sentence denotes  Lymphocyte count, ×109/L 1.10–3.20 0.75 (0.55–0.95) 0.72 (0.55–0.93) 0.81 (0.55–0.96) 0.5126
T208 23592-23682 Sentence denotes  Lymphocyte percentage, % 20.0–50.0 14.5 (8.5–18.1) 11.8 (8.1–17.8) 14.8 (8.9–19.2) 0.2271
T209 23683-23781 Sentence denotes  Platelet count, ×109/L 125–350 207.0 (153.0–258.0) 207.0 (145.0–264.5) 207.0 (154.5–247.0) 0.9358
T210 23782-23806 Sentence denotes Coagulation parameters†:
T211 23807-23916 Sentence denotes  Activated partial thromboplastin time, S 27.0–45.0 38.0 (34.8–42.2) 38.6 (35.4–42.9) 37.9 (34.7–41.6) 0.7342
T212 23917-23998 Sentence denotes  Prothrombin time, S 11.0–16.0 13.5 (12.6–14.2) 13.4 (12.7–14.2) 13.5 (12.6–14.2)
T213 23999-24072 Sentence denotes  D-dimer ≥ 0.5, μg/mL, n (%) 0.0–0.5 72 (53.3) 29 (48.3) 43 (57.3) 0.2976
T214 24073-24109 Sentence denotes Blood biochemistry and electrolyte‡:
T215 24110-24191 Sentence denotes  Albumin, g/L 33.0–55.0 29.7 (26.8–32.6) 30.4 (27.5–34.2) 28.7 (26.1–32.0) 0.0386
T216 24192-24281 Sentence denotes  Alanine transaminase, U/L 5–40 38.0 (24.5–58.5) 42.5 (29.0–72.5) 33.0 (23.0–54.0) 0.0424
T217 24282-24370 Sentence denotes  Total bilirubin, μmol/L 3.0–20.0 10.7 (7.3–14.0) 11.7 (8.6–14.0) 10.1 (6.7–14.0) 0.1305
T218 24371-24467 Sentence denotes  Blood urea nitrogen, mmol/L 2.90–8.20 4.77 (3.63–6.47) 5.52 (3.52–7.42) 4.65 (3.64–5.83) 0.1422
T219 24468-24562 Sentence denotes  Serum creatinine, μmol/L 57.0–111.0 69.3 (58.5–85.0) 69.7 (58.7–86.3) 68.0 (57.3–82.6) 0.9991
T220 24563-24653 Sentence denotes  Creatine kinase, U/L‡ 24–194 69.0 (47.0–130.0) 81.0 (52.0–165.0) 64.5 (40.0–105.5) 0.0288
T221 24654-24756 Sentence denotes  Lactate dehydrogenase, U/L 109–245 305.0 (224.5–380.5) 326.0 (225.0–402.0) 277.0 (224.5–367.0) 0.1233
T222 24757-24841 Sentence denotes  Glucose, mmol/L 3.90–6.10 6.40 (5.53–8.63) 6.37 (5.77–9.78) 6.55 (5.47–8.20) 0.3565
T223 24842-24939 Sentence denotes  Total carbon dioxide, mmol/L 20.0–29.0 24.1 (21.6–28.0) 23.6 (21.7–27.6) 24.6 (21.6–28.4) 0.3503
T224 24940-25034 Sentence denotes  Sodium, mmol/L 137.0–147.0 138.2 (135.9–140.3) 137.8 (135.3–140.1) 138.5 (136.5–140.4) 0.2621
T225 25035-25121 Sentence denotes  Potassium, mmol/L 3.50–5.30 3.75 (3.41–4.11) 3.82 (3.50–4.17) 3.65 (3.39–4.07) 0.1872
T226 25122-25142 Sentence denotes Cardiac biomarkers§:
T227 25143-25201 Sentence denotes  Creatine kinase-MB ≥ 6.6, ng/mL < 6.6 0 (0) 0 (0) 0 (0) –
T228 25202-25287 Sentence denotes  Hypersensitive cardiac troponin I ≥ 26.2, ng/L < 26.2 7 (5.2) 5 (8.3) 2 (2.7) 0.2779
T229 25288-25301 Sentence denotes Complications
T230 25302-25365 Sentence denotes  Acute liver dysfunction – 84 (62.2) 37 (61.7) 47 (62.7) 0.9052
T231 25366-25420 Sentence denotes  Hyperglycaemia – 64 (47.4) 31 (51.7) 33 (44.0) 0.3754
T232 25421-25482 Sentence denotes  Hospital-acquired infection – 8 (5.9) 1 (1.7) 7 (9.3) 0.1316
T233 25483-25534 Sentence denotes  Acute kidney injury – 3 (2.2) 0 (0) 3 (4.0) 0.3275
T234 25535-25589 Sentence denotes  Acute cardiac injury – 3 (2.2) 1 (1.7) 2 (2.7) 0.8447
T235 25590-25600 Sentence denotes Treatment:
T236 25601-25616 Sentence denotes  Oxygen therapy
T237 25617-25671 Sentence denotes  Nasal cannula – 102 (75.6) 48 (80.0) 64 (85.3) 0.4128
T238 25672-25723 Sentence denotes  Oxygen mask – 32 (23.7) 16 (26.7) 16 (21.3) 0.4690
T239 25724-25772 Sentence denotes  Without oxygen – 3 (2.2) 1 (1.7) 2 (2.7) 0.8447
T240 25773-25831 Sentence denotes  Antiviral therapy – 132 (97.8) 59 (98.3) 73 (97.3) 0.6953
T241 25832-25884 Sentence denotes  Antibiotics – 105 (79.5) 44 (73.3) 61 (81.3) 0.2666
T242 25885-25949 Sentence denotes  Immunoregulatory therapy – 79 (58.5) 37 (61.7) 42 (56.0) 0.5067
T243 25950-26005 Sentence denotes  Corticosteroids – 74 (54.8) 32 (53.3) 42 (56.0) 0.7570
T244 26006-26060 Sentence denotes  Immunoglobulin – 39 (28.9) 21 (35.0) 18 (24.0) 0.1612
T245 26061-26120 Sentence denotes  Vasoconstrictive agents – 13 (9.6) 6 (10.0) 7 (9.3) 0.8962
T246 26121-26170 Sentence denotes Requring ICU care – 9 (6.7) 0 (0) 9 (12.0) 0.0151
T247 26171-26277 Sentence denotes Total length of hospital stay, median (IQR), d – 29.0 (21.0–45.0) 25.0 (20.5–36.5) 33.0 (23.0–47.0) 0.0116
T248 26278-26335 Sentence denotes Values are median (IQR [range]) or numbers (percentages).
T249 26336-26462 Sentence denotes Abbreviations: IQR, interquartile range; n, number. aP values indicate differences between good-sleep and poor-sleep patients.
T250 26463-26513 Sentence denotes P < 0.05 was considered statistically significant.
T251 26514-26828 Sentence denotes †Data were missing for the measurement of activated partial thromboplastin time, prothrombin time, or D-dimer in five patients (8.3%), five patients (8.3%), and 10 patients (16.6%) in the good-sleep group, and six patients (8.0%), six patients (8.0%), and 10 patients (13.3%) in the poor-sleep group, respectively.
T252 26829-26974 Sentence denotes ‡Data regarding creatine kinase were missing for seven patients (11.7%) in the good-sleep group, and 11 patients (14.7%) in the poor-sleep group.
T253 26976-27041 Sentence denotes 3.5 Absolute lymphocyte count and neutrophil-to-lymphocyte ratio
T254 27042-27337 Sentence denotes Compared to patients in the good-sleep group, patients in the poor-sleep group had significantly decreased ALC on day 14 (median, 1.10 [IQR, 0.88–1.35] vs 1.32 [IQR, 1.04–1.59], P = 0.0055) and day 21 after hospital admission (median, 1.18 [IQR, 0.92–1.45] vs 1.48 [IQR, 1.10–1.98], P = 0.0034).
T255 27338-27601 Sentence denotes Patients in the poor-sleep group also had an increased NLR on day 14 (median, 3.17 [IQR, 2.27–4.66] vs 2.44 [IQR, 2.05–3.75], P = 0.0284) and day 21 (median, 2.73 [IQR, 2.10–5.90] vs 2.23 [IQR, 1.63–2.92], P = 0.0092) than those in the good-sleep group (Fig. 2 ).
T256 27602-28250 Sentence denotes The recovery rate based on ALC was higher in patients in the good-sleep group on day 14 (median, 56.91 [IQR, 8.67–94.54] vs 69.40 [IQR, 43.67–132.40], P = 0.0255) and day 21 (median, 61.40 [IQR, 26.81–102.82] vs 111.47 [IQR, 65.38–183.05], P = 0.0003) than those in the poor-sleep group; similar results were found regarding the deterioration based on an increased NLR on day 7 (median, −15.01 [IQR, −43.02–0.82] vs −39.24 [IQR, −60.34–-0.24], P = 0.0314), day 14 (median, −39.65 [IQR, −62.06–-12.94] vs −61.09 [IQR, −70.87––23.50], P = 0.0155), and day 21 (median, −51.40% [IQR, −61.08––22.36] vs −75.43 [IQR, −82.19–-47.77], P = 0.0003) (Fig. 2).
T257 28251-28326 Sentence denotes Fig. 2 Effects of self-reported sleep quality on recovery from lymphopenia.
T258 28327-28567 Sentence denotes Dynamic changes in absolute lymphocyte count (ALC; A) and neutrophil-to-lymphocyte ratio (NLR; B) within 24 h (baseline value), on day 7, 14, and 21 after hospital admission in patients with COVID-19 in the good-sleep and poor-sleep groups.
T259 28568-28756 Sentence denotes Dynamic changes in the ALC recovery rate (C) and NLR deterioration rate (D) on day 7, 14, and 21 after hospital admission in patients with COVID-19 in the good-sleep and poor-sleep groups.
T260 28757-28869 Sentence denotes Data were missing in five patients (8.3%) on day 7, and three patients (5.0%) on day 21 in the good-sleep group.
T261 28870-29390 Sentence denotes Data were missing in five patients (6.6%) on day 7, three patients (4.0%) on day 14, and four patients (5.3%) on day 21 in the poor-sleep group. ***P < 0.001 and ****P < 0.0001 when compared to the baseline value of the good-sleep group; §§P < 0.01 and §§§§P < 0.0001 when compared to baseline values of the poor-sleep group; ##P < 0.01 and ###P < 0.001 when compared to values on day 7 in the good-sleep group; &&P < 0.01 and &&&P < 0.001 when compared to values on day 7 in the poor-sleep group; N.S., not significant.
T262 29391-29441 Sentence denotes P < 0.05 was considered statistically significant.
T263 29443-29456 Sentence denotes 4 Discussion
T264 29457-29686 Sentence denotes To our knowledge, this report is the first case series to study the effects of sleep quality on the recovery from lymphopenia, deterioration based on an increased NLR, and clinical outcomes in hospitalized patients with COVID-19.
T265 29687-29900 Sentence denotes Among the 135 patients included in this study, 44.4% of patients reported at least two weeks of good-sleep, and 55.6% patients reported at least two weeks of poor-sleep within three weeks after hospital admission.
T266 29901-30079 Sentence denotes There were no significant between-group differences regarding demographic and baseline characteristics, as well as laboratory parameters upon admission and in-hospital treatment.
T267 30080-30396 Sentence denotes Also, no significant differences between the good-sleep group and poor-sleep groups were detected regarding ALC and its recovery rate, as well as NLR on day 7 after hospital admission, indicating an equivalent immune function and its recovery rate between the two groups during the early phase of hospital admission.
T268 30397-30557 Sentence denotes However, at least 2 weeks of poor sleep during hospitalization was associated with a slow recovery from lymphopenia and an increase in the deterioration of NLR.
T269 30558-30919 Sentence denotes On day 14 and day 21 after hospital admission, patients in the poor-sleep group had reduced ALC and associated recovery rate, as well as increased NLR and associated deterioration percentage compared to patients in the good-sleep group, suggesting detrimental effects of a sustained period of poor sleep on recovery of immune function in patients with COVID-19.
T270 30920-31197 Sentence denotes Furthermore, patients in the poor-sleep group had an increased incidence of HAI (seven [9.3%] vs one [1.7%]) compared to those in the poor-sleep group, which may be due to a slower recovery from lymphopenia in the poor-sleep group; however, this difference was not significant.
T271 31198-31389 Sentence denotes Additionally, the health condition of 12.0% of patients with COVID-19 with poor-sleep deteriorated, requiring ICU care, whereas none of the patients in the good-sleep group required ICU care.
T272 31390-31512 Sentence denotes Patients in the poor-sleep group spent an average of eight days longer in the hospital than those in the good-sleep group.
T273 31513-31770 Sentence denotes Our present study confirms recent studies showing that a continuous and sustained decrease in the ALC, or increase in NLR, is closely associated with the disease aggravation in patients with COVID-19 (Tan et al., 2020, Wang et al., 2020, Zhou et al., 2020).
T274 31771-32107 Sentence denotes However, SARS-CoV-2 could be detected in the cerebrospinal fluid by PCR in a case of COVID-19 encephalitis (Huang et al., 2020b), and neurologic syndrome was found after the onset of COVID-19, including Guillain-Barré Syndrome, polyneuritis cranialis, and stroke (Toscano et al., 2020, Gutierrez-Ortiz et al., 2020, Oxley et al., 2020).
T275 32108-32259 Sentence denotes Therefore, bidirectional causality might exist between poor sleep quality during hospitalization and worse clinical outcomes in patients with COVID-19.
T276 32260-32450 Sentence denotes In patients with COVID-19 with poor-sleep, the most important etiological causes of poor-sleep were environmental and psychosocial factors, which accounted for 85.3% and 60.0%, respectively.
T277 32451-32594 Sentence denotes Physical discomfort caused by illness was another major factor that contributed to poor-sleep during hospitalization in patients with COVID-19.
T278 32595-32842 Sentence denotes These factors are also the major causal factors of sleep disturbance in ICU patients and could negatively affect recovery from critical illness (Delaney et al., 2015, Devlin et al., 2018, Friese, 2008, Kamdar et al., 2012, Pulak and Jensen, 2016).
T279 32843-33320 Sentence denotes Therefore, psychological treatment (spiritual encouragement, psychological comfort, emotional support, psychotropic drug therapy, etc.), improving the ward environment (reducing noise, improving lighting, segregating patients from each other by curtains, etc.), and interventions to alleviate psychological comfort (adequate analgesia, proper sedation, relieving breathing difficulty, etc.) are essential to improve the sleep quality of patients with COVID-19 in non-ICU wards.
T280 33321-33424 Sentence denotes As a retrospective study, there were no objective tools for sleep assessment in patients with COVID-19.
T281 33425-33626 Sentence denotes The RCSQ is empirically valid and the most widely used subjective survey instrument for assessing the quality of ICU patients' sleep (Nagatomo et al., 2020, Richards et al., 2000, Simons et al., 2018).
T282 33627-33811 Sentence denotes In a clinical study of 70 ICU patients, the RCSQ was validated against polysomnography (PSG) (Richards et al., 2000), which is considered the gold standard method for evaluating sleep.
T283 33812-34159 Sentence denotes We chose the RCSQ for assessing the sleep quality of patients with COVID-19 in non-ICU wards, since the frequent shifting of duty during ward-rounds, and the isolated environment without family member' companion in non-ICU ward for patients with COVID-19, are similar to that in the ICU wards for patients who are recovering from critical illness.
T284 34160-34451 Sentence denotes Since not all patients were able to accurately recollect and assess their daily sleep quality during their hospitalization, we broadened the application scope of the RCSQ and only assessed the overall sleep quality within the first week, second week, and third week after hospital admission.
T285 34452-34631 Sentence denotes In order to minimize different forms of bias, including recollection and response bias, patients with COVID-19 who were unsure of their sleep quality were excluded from the study.
T286 34632-34875 Sentence denotes We also lowered the upper limit of the RCSQ score that defines poor-sleep quality (≤50) to minimize bias, while the cut-off point differentiating good and poor sleep was 70/100 in previous studies (Mannion et al., 2019, McKinley et al., 2013).
T287 34876-34943 Sentence denotes Patients with at least two RCSQ scores of 50–70 were also excluded.
T288 34944-35151 Sentence denotes After assessment with the RCSQ, overall sleep quality was further confirmed using the Chinese version of the PSQI, which has been shown to be reliable and valid for the Chinese population (Liu et al., 1996).
T289 35152-35331 Sentence denotes The PSQI could discriminate between poor and good sleep quality over the preceding 30-days and has been widely used in clinical and non-clinical settings (Mollayeva et al., 2016).
T290 35332-35477 Sentence denotes In our study, we used both the RCSQ and the PSQI to better reflect the subjective sleep quality of patients with COVID-19 during hospitalization.
T291 35478-35573 Sentence denotes Furthermore, patients were excluded in cases of inconsistency between the RCSQ and PSQI scores.
T292 35574-35788 Sentence denotes In addition, after patients' self-reported sleep assessment, we further checked patients' overall sleep quality by asking their hospital roommates, as well as the doctors and nurses responsible for their treatment.
T293 35789-35838 Sentence denotes There were some notable limitations in our study.
T294 35839-35997 Sentence denotes First, a few cases had incomplete documentation of the laboratory parameters at each specific time point, due to lack of necessity for continuous daily tests.
T295 35998-36074 Sentence denotes Second, it was a single-center retrospective study with a small sample size.
T296 36075-36164 Sentence denotes Future prospective studies with large patient cohorts are needed to validate the results.
T297 36165-36331 Sentence denotes Third, although multiple criteria for grouping based on the RCSQ and the PSQI was strictly defined in this study, there could still be recollection and response bias.
T298 36332-36398 Sentence denotes Therefore, objective sleep monitoring is needed in future studies.
T299 36400-36414 Sentence denotes 5 Conclusions
T300 36415-36623 Sentence denotes Poor-sleep quality in patients with COVID-19 was associated with a slow recovery from lymphopenia, an increased risk of becoming critically ill and requiring ICU care, and prolonged duration of hospital stay.
T301 36624-36990 Sentence denotes It is important to adopt comprehensive treatment measures during hospitalization to improve the sleep quality of patients with mild or moderate lymphopenia in the early stage of COVID-19 infection to promote recovery of immune function and prevent the need for ICU care, thereby reducing the great risk posed by the COVID-19 crisis regarding critical care resources.
T302 36992-37012 Sentence denotes Author contributions
T303 37013-37156 Sentence denotes SY and JZ had full access to all data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
T304 37157-37192 Sentence denotes Concept and design: SY, KH, and YS.
T305 37193-37279 Sentence denotes Acquisition, analysis, or interpretation of data: JZ, DX, BX, YZ, HH, HL, HC, and YBS.
T306 37280-37311 Sentence denotes Drafting of the manuscript: JZ.
T307 37312-37387 Sentence denotes Critical revision of the manuscript for important intellectual content: KH.
T308 37388-37413 Sentence denotes Statistical analysis: JZ.
T309 37414-37477 Sentence denotes Administrative, technical, or material support: DX, YS, and SY.
T310 37478-37501 Sentence denotes Supervision: YS and SY.
T311 37503-37524 Sentence denotes 7 Data visualization
T312 37525-37659 Sentence denotes After publication, the data supporting the findings of this study can be provided by the corresponding author upon reasonable request.
T313 37660-37795 Sentence denotes Participant data without names and identifiers can be provided by the corresponding author and the Wuhan Union Hospital after approval.
T314 37796-37936 Sentence denotes The research team will provide an email address for communication purposes once approval is obtained regarding sharing the data with others.
T315 37937-38096 Sentence denotes The proposal with detailed description of the study objectives and statistical analysis plan will be needed for evaluation of the purpose for the data request.
T316 38097-38172 Sentence denotes Additional materials may also be required during the process of evaluation.
T317 38174-38198 Sentence denotes Declaration of interests
T318 38199-38241 Sentence denotes The authors declare no competing interest.
T319 38243-38250 Sentence denotes Funding
T320 38251-38375 Sentence denotes This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
T321 38377-38407 Sentence denotes Appendix A Supplementary data
T322 38408-38485 Sentence denotes The following are the Supplementary data to this article:Supplementary data 1
T323 38487-38501 Sentence denotes Acknowledgment
T324 38502-38615 Sentence denotes We thank all the patients and their families, as well as the doctors in charge and nurses, involved in the study.
T325 38616-38728 Sentence denotes Appendix A Supplementary data to this article can be found online at https://doi.org/10.1016/j.bbi.2020.05.075.

2_test

Id Subject Object Predicate Lexical cue
32512133-32105632-16126960 3126-3130 32105632 denotes 2020
32512133-12781533-16126961 3274-3278 12781533 denotes 2003
32512133-28893197-16126962 3332-3336 28893197 denotes 2017
32512133-32171076-16126964 4198-4202 32171076 denotes 2020
32512133-32296069-16126965 4297-4301 32296069 denotes 2020
32512133-30920354-16126966 5068-5072 30920354 denotes 2019
32512133-26075423-16126967 5113-5117 26075423 denotes 2015
32512133-30920354-16126968 5194-5198 30920354 denotes 2019
32512133-17910386-16126969 5405-5409 17910386 denotes 2007
32512133-25061767-16126970 5418-5422 25061767 denotes 2015
32512133-15126529-16126971 5441-5445 15126529 denotes 2004
32512133-21496482-16126972 5567-5571 21496482 denotes 2011
32512133-19139325-16126973 5745-5749 19139325 denotes 2009
32512133-30475977-16126974 5764-5768 30475977 denotes 2019
32512133-22215923-16126975 5784-5788 22215923 denotes 2012
32512133-26118561-16126976 5806-5810 26118561 denotes 2015
32512133-24117403-16126977 5913-5917 24117403 denotes 2014
32512133-32071722-16126978 10407-10411 32071722 denotes 2020
32512133-11227580-16126979 10430-10434 11227580 denotes 2000
32512133-30290829-16126980 10451-10455 30290829 denotes 2018
32512133-32296069-16126981 31726-31730 32296069 denotes 2020
32512133-32171076-16126982 31764-31768 32171076 denotes 2020
32512133-25852963-16126983 32756-32760 25852963 denotes 2015
32512133-30113379-16126984 32777-32781 30113379 denotes 2018
32512133-18176314-16126985 32791-32795 18176314 denotes 2008
32512133-21220271-16126986 32812-32816 21220271 denotes 2012
32512133-24916753-16126987 32836-32840 24916753 denotes 2016
32512133-32071722-16126988 33576-33580 32071722 denotes 2020
32512133-11227580-16126989 33599-33603 11227580 denotes 2000
32512133-30290829-16126990 33620-33624 30290829 denotes 2018
32512133-11227580-16126991 33738-33742 11227580 denotes 2000
32512133-24290043-16126992 34869-34873 24290043 denotes 2013
32512133-26163057-16126993 35325-35329 26163057 denotes 2016