PMC:7274950 / 1499-1869 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T16","span":{"begin":37,"end":38},"obj":"GO:0000805"},{"id":"T17","span":{"begin":56,"end":65},"obj":"GO:0005764"},{"id":"T18","span":{"begin":128,"end":132},"obj":"SO:0000704"},{"id":"T19","span":{"begin":254,"end":260},"obj":"CHEBI:18059;CHEBI:18059"},{"id":"T20","span":{"begin":295,"end":298},"obj":"PR:Q9SMQ6"},{"id":"T21","span":{"begin":308,"end":318},"obj":"MOP:0001479"},{"id":"T22","span":{"begin":330,"end":354},"obj":"CHEBI:30087;CHEBI:30087"},{"id":"T23","span":{"begin":361,"end":364},"obj":"PR:Q9SMQ6"},{"id":"T41907","span":{"begin":37,"end":38},"obj":"GO:0000805"},{"id":"T48067","span":{"begin":56,"end":65},"obj":"GO:0005764"},{"id":"T82620","span":{"begin":128,"end":132},"obj":"SO:0000704"},{"id":"T7827","span":{"begin":254,"end":260},"obj":"CHEBI:18059;CHEBI:18059"},{"id":"T52422","span":{"begin":295,"end":298},"obj":"PR:Q9SMQ6"},{"id":"T70815","span":{"begin":308,"end":318},"obj":"MOP:0001479"},{"id":"T68709","span":{"begin":330,"end":354},"obj":"CHEBI:30087;CHEBI:30087"},{"id":"T92531","span":{"begin":361,"end":364},"obj":"PR:Q9SMQ6"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"53","span":{"begin":254,"end":260},"obj":"Chemical"},{"id":"54","span":{"begin":272,"end":293},"obj":"Chemical"},{"id":"55","span":{"begin":295,"end":298},"obj":"Chemical"},{"id":"56","span":{"begin":330,"end":354},"obj":"Chemical"},{"id":"57","span":{"begin":356,"end":364},"obj":"Chemical"},{"id":"58","span":{"begin":0,"end":13},"obj":"Disease"},{"id":"59","span":{"begin":15,"end":17},"obj":"Disease"},{"id":"60","span":{"begin":37,"end":82},"obj":"Disease"},{"id":"61","span":{"begin":160,"end":200},"obj":"Disease"}],"attributes":[{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"MESH:D008055"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"MESH:C018549"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:C063288"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:D000795"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D004402"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D016464"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D000795"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":56,"end":65},"obj":"Body_part"},{"id":"T5","span":{"begin":128,"end":132},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma63836"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T17","span":{"begin":0,"end":13},"obj":"Disease"},{"id":"T18","span":{"begin":15,"end":17},"obj":"Disease"},{"id":"T19","span":{"begin":56,"end":82},"obj":"Disease"}],"attributes":[{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0010526"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0010526"},{"id":"A19","pred":"mondo_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/MONDO_0002561"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T12","span":{"begin":22,"end":23},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T13","span":{"begin":56,"end":65},"obj":"http://purl.obolibrary.org/obo/GO_0005764"},{"id":"T14","span":{"begin":126,"end":127},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T15","span":{"begin":128,"end":132},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T16","span":{"begin":201,"end":202},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T17","span":{"begin":210,"end":211},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T18","span":{"begin":224,"end":225},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":15,"end":17},"obj":"Chemical"},{"id":"T3","span":{"begin":134,"end":137},"obj":"Chemical"},{"id":"T4","span":{"begin":206,"end":209},"obj":"Chemical"},{"id":"T5","span":{"begin":254,"end":260},"obj":"Chemical"},{"id":"T6","span":{"begin":272,"end":293},"obj":"Chemical"},{"id":"T7","span":{"begin":295,"end":298},"obj":"Chemical"},{"id":"T8","span":{"begin":361,"end":364},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_73631"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_28661"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_28260"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_18313"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_18313"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_18313"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":66,"end":73},"obj":"http://purl.obolibrary.org/obo/GO_0051235"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":295,"end":298},"obj":"GlycoEpitope"},{"id":"T2","span":{"begin":361,"end":364},"obj":"GlycoEpitope"}],"attributes":[{"id":"A1","pred":"glyco_epitope_db_id","subj":"T1","obj":"http://www.glycoepitope.jp/epitopes/EP0071"},{"id":"A2","pred":"glyco_epitope_db_id","subj":"T2","obj":"http://www.glycoepitope.jp/epitopes/EP0071"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T14","span":{"begin":0,"end":139},"obj":"Sentence"},{"id":"T15","span":{"begin":140,"end":370},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fabry disease (FD) is a progressive, X-linked inherited lysosomal storage disorder caused by mutations in the α-Galactosidase A gene (GLA). Partial or complete deficiency of the enzyme α-Galactosidase A (α-Gal A) results in a progressive accumulation of lipids, primarily globotriaosylceramide (Gb3) and its deacylated derivative globotriaosylsphingosine (lyso-Gb3) [1]."}