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PMC:7274950 / 10848-11271 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T136 94-110 UBERON:0005409 denotes gastrointestinal
T137 140-144 UBERON:0000104 denotes life
T138 153-159 UBERON:0001969 denotes plasma
T139 165-168 PR:Q9SMQ6 denotes Gb3
T140 186-189 PR:Q9SMQ6 denotes Gb3
T141 190-200 GO:0016234 denotes inclusions
T142 206-211 UBERON:0002113;CL:1000497 denotes renal
T143 212-217 CL:1000497 denotes cells
T144 254-263 CL:0000653 denotes podocytes
T145 396-401 UBERON:0000062 denotes organ
T9604 94-110 UBERON:0005409 denotes gastrointestinal
T14185 140-144 UBERON:0000104 denotes life
T5065 153-159 UBERON:0001969 denotes plasma
T88556 165-168 PR:Q9SMQ6 denotes Gb3
T99402 186-189 PR:Q9SMQ6 denotes Gb3
T63298 190-200 GO:0016234 denotes inclusions
T77613 206-211 UBERON:0002113;CL:1000497 denotes renal
T37944 212-217 CL:1000497 denotes cells
T76245 254-263 CL:0000653 denotes podocytes
T26927 396-401 UBERON:0000062 denotes organ

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
277 320-328 Species denotes patients Tax:9606
278 160-168 Chemical denotes lyso-Gb3 MESH:C063288
279 40-53 Disease denotes Fabry disease MESH:D000795
280 73-89 Disease denotes neuropathic pain MESH:D009437
281 94-119 Disease denotes gastrointestinal symptoms MESH:D012817

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T53 153-159 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T54 206-217 Body_part denotes renal cells http://purl.org/sig/ont/fma/fma86785
T55 212-217 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 396-401 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T28 396-401 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T61 40-53 Disease denotes Fabry disease http://purl.obolibrary.org/obo/MONDO_0010526

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T119 4-7 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T120 8-9 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T121 153-159 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T122 212-217 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T123 224-225 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T124 295-299 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T125 295-299 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T126 396-401 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T127 409-412 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T27 165-168 Chemical denotes Gb3 http://purl.obolibrary.org/obo/CHEBI_18313
T28 186-189 Chemical denotes Gb3 http://purl.obolibrary.org/obo/CHEBI_18313
T29 295-299 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T38 85-89 Phenotype denotes pain http://purl.obolibrary.org/obo/HP_0012531

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T5 165-168 GlycoEpitope denotes Gb3 http://www.glycoepitope.jp/epitopes/EP0071
T6 186-189 GlycoEpitope denotes Gb3 http://www.glycoepitope.jp/epitopes/EP0071

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T79 0-264 Sentence denotes ERT has a beneficial clinical impact in Fabry disease, as it can relieve neuropathic pain and gastrointestinal symptoms, improve quality of life, reduce plasma lyso-Gb3 levels and clear Gb3 inclusions from renal cells, with a dose-dependent mechanism in podocytes.
T80 265-423 Sentence denotes Evidence, mainly derived from male studies, shows that patients may benefit from early treatment initiation, before major clinical organ damage has developed.