PMC:7274940 / 9994-11015
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7274940","sourcedb":"PMC","sourceid":"7274940","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7274940","text":"Ocular involvement with Coronavirus family has been shown in various publications [10, 13, 14]. On January 22, 2020, when a visiting doctor in Wuhan developed conjunctivitis, and later yielded positive for SARS-CoV-2, call for research on ocular transmission and involvement of SARS-CoV-2 was made [14]. In a prospective study by Xia et al. [10], tear and conjunctival secretions of 30 COVID-19 patients were collected, and the presence of the virus was evaluated by RT-PCR [10]. Virus was detected in only one patient’s conjunctival scrapes who had conjunctivitis at the time of specimen collection; therefore, it was proposed that the virus only existed in the tear and conjunctiva of the patients with conjunctivitis. On the other hand, in the same study, it was stated that the sample volume of tear and conjunctival secretion might be insufficient for RT-PCR detection, and therefore, the possibility of viral particles’ presence in tears and conjunctiva should not be ignored in patients without conjunctivitis.[10]","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"314","span":{"begin":24,"end":35},"obj":"Species"},{"id":"315","span":{"begin":206,"end":216},"obj":"Species"},{"id":"316","span":{"begin":278,"end":288},"obj":"Species"},{"id":"317","span":{"begin":395,"end":403},"obj":"Species"},{"id":"318","span":{"begin":511,"end":518},"obj":"Species"},{"id":"319","span":{"begin":691,"end":699},"obj":"Species"},{"id":"320","span":{"begin":985,"end":993},"obj":"Species"},{"id":"321","span":{"begin":159,"end":173},"obj":"Disease"},{"id":"322","span":{"begin":386,"end":394},"obj":"Disease"},{"id":"323","span":{"begin":550,"end":564},"obj":"Disease"},{"id":"324","span":{"begin":705,"end":719},"obj":"Disease"},{"id":"325","span":{"begin":1002,"end":1016},"obj":"Disease"}],"attributes":[{"id":"A314","pred":"tao:has_database_id","subj":"314","obj":"Tax:11118"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"Tax:2697049"},{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"Tax:2697049"},{"id":"A317","pred":"tao:has_database_id","subj":"317","obj":"Tax:9606"},{"id":"A318","pred":"tao:has_database_id","subj":"318","obj":"Tax:9606"},{"id":"A319","pred":"tao:has_database_id","subj":"319","obj":"Tax:9606"},{"id":"A320","pred":"tao:has_database_id","subj":"320","obj":"Tax:9606"},{"id":"A321","pred":"tao:has_database_id","subj":"321","obj":"MESH:D003231"},{"id":"A322","pred":"tao:has_database_id","subj":"322","obj":"MESH:C000657245"},{"id":"A323","pred":"tao:has_database_id","subj":"323","obj":"MESH:D003231"},{"id":"A324","pred":"tao:has_database_id","subj":"324","obj":"MESH:D003231"},{"id":"A325","pred":"tao:has_database_id","subj":"325","obj":"MESH:D003231"},{"subj":"314","pred":"source","obj":"LitCovid-PubTator"},{"subj":"315","pred":"source","obj":"LitCovid-PubTator"},{"subj":"316","pred":"source","obj":"LitCovid-PubTator"},{"subj":"317","pred":"source","obj":"LitCovid-PubTator"},{"subj":"318","pred":"source","obj":"LitCovid-PubTator"},{"subj":"319","pred":"source","obj":"LitCovid-PubTator"},{"subj":"320","pred":"source","obj":"LitCovid-PubTator"},{"subj":"321","pred":"source","obj":"LitCovid-PubTator"},{"subj":"322","pred":"source","obj":"LitCovid-PubTator"},{"subj":"323","pred":"source","obj":"LitCovid-PubTator"},{"subj":"324","pred":"source","obj":"LitCovid-PubTator"},{"subj":"325","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T46","span":{"begin":347,"end":351},"obj":"Body_part"},{"id":"T47","span":{"begin":663,"end":667},"obj":"Body_part"},{"id":"T48","span":{"begin":672,"end":683},"obj":"Body_part"},{"id":"T49","span":{"begin":734,"end":738},"obj":"Body_part"},{"id":"T50","span":{"begin":799,"end":803},"obj":"Body_part"},{"id":"T51","span":{"begin":938,"end":943},"obj":"Body_part"},{"id":"T52","span":{"begin":948,"end":959},"obj":"Body_part"}],"attributes":[{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma59756"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma59756"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma59756"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma59756"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma59011"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":672,"end":683},"obj":"Body_part"},{"id":"T14","span":{"begin":734,"end":738},"obj":"Body_part"},{"id":"T15","span":{"begin":948,"end":959},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T15","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T75","span":{"begin":159,"end":173},"obj":"Disease"},{"id":"T76","span":{"begin":206,"end":214},"obj":"Disease"},{"id":"T77","span":{"begin":278,"end":286},"obj":"Disease"},{"id":"T78","span":{"begin":386,"end":394},"obj":"Disease"},{"id":"T79","span":{"begin":550,"end":564},"obj":"Disease"},{"id":"T80","span":{"begin":705,"end":719},"obj":"Disease"},{"id":"T81","span":{"begin":1002,"end":1016},"obj":"Disease"}],"attributes":[{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T62","span":{"begin":43,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T63","span":{"begin":107,"end":109},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T64","span":{"begin":122,"end":123},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T65","span":{"begin":307,"end":308},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T66","span":{"begin":444,"end":449},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T67","span":{"begin":480,"end":485},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T68","span":{"begin":637,"end":642},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T69","span":{"begin":672,"end":683},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T70","span":{"begin":672,"end":683},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T71","span":{"begin":948,"end":959},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T72","span":{"begin":948,"end":959},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"}],"attributes":[{"subj":"T62","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T7","span":{"begin":369,"end":379},"obj":"http://purl.obolibrary.org/obo/GO_0046903"},{"id":"T8","span":{"begin":821,"end":830},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"2_test","denotations":[{"id":"32504100-32035510-45244944","span":{"begin":87,"end":89},"obj":"32035510"},{"id":"T22104","span":{"begin":87,"end":89},"obj":"32035510"}],"attributes":[{"subj":"32504100-32035510-45244944","pred":"source","obj":"2_test"},{"subj":"T22104","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T42","span":{"begin":159,"end":173},"obj":"Phenotype"},{"id":"T43","span":{"begin":550,"end":564},"obj":"Phenotype"},{"id":"T44","span":{"begin":705,"end":719},"obj":"Phenotype"},{"id":"T45","span":{"begin":1002,"end":1016},"obj":"Phenotype"}],"attributes":[{"id":"A42","pred":"hp_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A43","pred":"hp_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A44","pred":"hp_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T108","span":{"begin":0,"end":95},"obj":"Sentence"},{"id":"T109","span":{"begin":96,"end":303},"obj":"Sentence"},{"id":"T110","span":{"begin":304,"end":479},"obj":"Sentence"},{"id":"T111","span":{"begin":480,"end":720},"obj":"Sentence"},{"id":"T112","span":{"begin":721,"end":1021},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T108","pred":"source","obj":"LitCovid-sentences"},{"subj":"T109","pred":"source","obj":"LitCovid-sentences"},{"subj":"T110","pred":"source","obj":"LitCovid-sentences"},{"subj":"T111","pred":"source","obj":"LitCovid-sentences"},{"subj":"T112","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93abec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#c5ec93"},{"id":"LitCovid-PD-UBERON","color":"#ec93df"},{"id":"LitCovid-PD-MONDO","color":"#93ecdf"},{"id":"LitCovid-PD-CLO","color":"#ecc593"},{"id":"LitCovid-PD-GO-BP","color":"#ab93ec"},{"id":"2_test","color":"#95ec93"},{"id":"LitCovid-PD-HP","color":"#ec93af"},{"id":"LitCovid-sentences","color":"#93c9ec"}]}]}}