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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 25-49 Disease denotes coronavirus disease 2019 MESH:C000657245
6 68-92 Disease denotes Coronavirus disease 2019 MESH:C000657245
7 94-102 Disease denotes COVID-19 MESH:C000657245
8 164-172 Disease denotes COVID-19 MESH:C000657245
9 423-431 Disease denotes COVID-19 MESH:C000657245
12 708-716 Species denotes patients Tax:9606
13 699-707 Disease denotes COVID-19 MESH:C000657245
31 1386-1389 Gene denotes CRP Gene:1401
32 1403-1406 Gene denotes PCT Gene:796
33 1551-1554 Gene denotes age Gene:5973
34 930-933 Gene denotes age Gene:5973
35 865-873 Species denotes patients Tax:9606
36 941-949 Species denotes patients Tax:9606
37 996-1004 Species denotes patients Tax:9606
38 1276-1284 Species denotes Patients Tax:9606
39 1497-1505 Species denotes patients Tax:9606
40 1569-1577 Species denotes patients Tax:9606
41 856-864 Disease denotes COVID-19 MESH:C000657245
42 1032-1050 Disease denotes ocular abnormality MESH:D005124
43 1082-1091 Disease denotes hyperemia MESH:D006940
44 1102-1110 Disease denotes epiphora MESH:D007766
45 1178-1192 Disease denotes conjunctivitis MESH:D003231
46 1206-1218 Disease denotes episcleritis MESH:D015423
47 1583-1588 Disease denotes fever MESH:D005334
50 1713-1716 Gene denotes age Gene:5973
51 1718-1728 Disease denotes high fever MESH:D005334
60 1971-1977 Species denotes people Tax:9606
61 1985-2000 Species denotes new coronavirus Tax:2697049
62 2002-2005 Species denotes COV Tax:11118
63 2056-2073 Species denotes novel coronavirus Tax:2697049
64 2129-2139 Species denotes SARS-CoV-2 Tax:2697049
65 1909-1918 Disease denotes pneumonia MESH:D011014
66 2174-2198 Disease denotes Coronavirus Disease 2019 MESH:C000657245
67 2200-2208 Disease denotes COVID-19 MESH:C000657245
74 2437-2443 Species denotes Turkey Tax:9103
75 2548-2556 Species denotes patients Tax:9606
76 2560-2566 Species denotes Turkey Tax:9103
77 2497-2505 Disease denotes COVID-19 MESH:C000657245
78 2587-2593 Disease denotes deaths MESH:D003643
79 2679-2687 Disease denotes COVID-19 MESH:C000657245
97 2853-2857 Species denotes CoVs Tax:11118
98 2878-2884 Species denotes humans Tax:9606
99 2910-2918 Species denotes MERS-CoV Tax:1335626
100 2920-2928 Species denotes SARS-CoV Tax:694009
101 2945-2955 Species denotes SARS-CoV-2 Tax:2697049
102 2975-2979 Species denotes CoVs Tax:11118
103 3118-3127 Species denotes HCoV-NL63 Tax:277944
104 3132-3140 Species denotes SARS-CoV Tax:694009
105 3278-3287 Species denotes HCoV-NL63 Tax:277944
106 3315-3323 Species denotes SARS-CoV Tax:694009
107 3368-3376 Species denotes patients Tax:9606
108 2892-2896 Species denotes NL63 Tax:277944
109 2986-2996 Disease denotes infections MESH:D007239
110 3218-3232 Disease denotes conjunctivitis MESH:D003231
111 3237-3250 Disease denotes bronchiolitis MESH:D001988
112 3548-3557 Disease denotes infection MESH:D007239
113 3623-3645 Disease denotes hematogenous infection MESH:D007239
119 3767-3775 Species denotes SARS-CoV Tax:694009
120 3780-3790 Species denotes SARS-CoV-2 Tax:2697049
121 4045-4055 Species denotes SARS-CoV-2 Tax:2697049
122 4171-4179 Species denotes patients Tax:9606
123 4162-4170 Disease denotes COVID-19 MESH:C000657245
127 4353-4357 Gene denotes Kars Gene:100550965
128 4323-4327 Gene denotes Kars Gene:100550965
129 4359-4365 Species denotes Turkey Tax:9103
148 5206-5224 Gene denotes C-reactive protein Gene:1401
149 5226-5229 Gene denotes CRP Gene:1401
150 5321-5336 Gene denotes creatine kinase Gene:51727
151 5338-5340 Gene denotes CK Gene:51727
152 5232-5246 Gene denotes pro-calcitonin Gene:796
153 4646-4650 Gene denotes Kars Gene:3735
154 5248-5251 Gene denotes PCT Gene:796
155 5383-5386 Gene denotes age Gene:5973
156 4612-4620 Species denotes patients Tax:9606
157 4900-4910 Species denotes SARS-CoV-2 Tax:2697049
158 5050-5058 Species denotes patients Tax:9606
159 5078-5085 Species denotes patient Tax:9606
160 4697-4705 Disease denotes COVID-19 MESH:C000657245
161 4725-4733 Disease denotes COVID-19 MESH:C000657245
162 4963-4978 Disease denotes viral pneumonia
163 4989-4997 Disease denotes COVID-19 MESH:C000657245
164 5096-5101 Disease denotes fever MESH:D005334
165 5422-5427 Disease denotes Fever MESH:D005334
167 5709-5724 Disease denotes Ocular symptoms MESH:D051271
192 6330-6333 Gene denotes age Gene:5973
193 6184-6192 Species denotes patients Tax:9606
194 6266-6274 Species denotes patients Tax:9606
195 6341-6349 Species denotes patients Tax:9606
196 6400-6408 Species denotes patients Tax:9606
197 6437-6447 Species denotes SARS-CoV-2 Tax:2697049
198 6570-6578 Species denotes patients Tax:9606
199 6601-6609 Species denotes patients Tax:9606
200 6630-6638 Species denotes patients Tax:9606
201 6674-6682 Species denotes patients Tax:9606
202 6712-6720 Species denotes patients Tax:9606
203 6790-6798 Species denotes patients Tax:9606
204 6859-6867 Species denotes patients Tax:9606
205 6932-6940 Species denotes patients Tax:9606
206 7010-7018 Species denotes patients Tax:9606
207 6219-6227 Disease denotes COVID-19 MESH:C000657245
208 6583-6588 Disease denotes fever MESH:D005334
209 6614-6619 Disease denotes cough MESH:D003371
210 6643-6663 Disease denotes respiratory distress MESH:D012128
211 6687-6695 Disease denotes headache MESH:D006261
212 6895-6915 Disease denotes SARS CoV-2 pneumonia MESH:C000657245
213 6954-6974 Disease denotes SARS CoV-2 pneumonia MESH:C000657245
214 7041-7061 Disease denotes respiratory distress MESH:D012128
215 7088-7108 Disease denotes SARS CoV-2 pneumonia MESH:C000657245
223 8101-8104 Gene denotes CRP Gene:1401
224 8142-8145 Gene denotes PCT Gene:796
225 8271-8273 Gene denotes CK Gene:51727
226 7786-7789 Gene denotes Age Gene:5973
227 7691-7699 Species denotes Patients Tax:9606
228 7733-7741 Species denotes Patients Tax:9606
229 7830-7835 Disease denotes Fever MESH:D005334
233 7599-7602 Gene denotes Age Gene:5973
234 7646-7654 Species denotes patients Tax:9606
235 7604-7609 Disease denotes fever MESH:D005334
238 8391-8405 Gene denotes pro-calcitonin Gene:796
239 8387-8390 Gene denotes PCT Gene:796
248 7295-7298 Gene denotes CRP Gene:1401
249 7567-7569 Gene denotes CK Gene:51727
250 7300-7303 Gene denotes PCT Gene:796
251 7147-7150 Gene denotes age Gene:5973
252 7194-7202 Species denotes patients Tax:9606
253 7349-7357 Species denotes patients Tax:9606
254 7486-7494 Species denotes patients Tax:9606
255 7152-7157 Disease denotes fever MESH:D005334
260 9694-9703 Disease denotes Hyperemia MESH:D006940
261 9795-9809 Disease denotes conjunctivitis MESH:D003231
262 9820-9832 Disease denotes Episcleritis MESH:D015423
263 9842-9873 Disease denotes Ocular symptoms  Photophobia 15 MESH:D051271
283 8727-8730 Gene denotes CRP Gene:1401
284 8991-8994 Gene denotes CRP Gene:1401
285 9163-9166 Gene denotes CRP Gene:1401
286 9348-9351 Gene denotes CRP Gene:1401
287 9501-9504 Gene denotes CRP Gene:1401
288 9571-9573 Gene denotes CK Gene:51727
289 9480-9483 Gene denotes PCT Gene:796
290 9365-9368 Gene denotes PCT Gene:796
291 9180-9183 Gene denotes PCT Gene:796
292 9032-9035 Gene denotes PCT Gene:796
293 8752-8755 Gene denotes PCT Gene:796
294 8571-8579 Species denotes patients Tax:9606
295 8581-8590 Disease denotes Hyperemia MESH:D006940
296 8628-8633 Disease denotes fever MESH:D005334
297 8680-8700 Disease denotes SARS CoV-2 pneumonia MESH:C000657245
298 8900-8905 Disease denotes fever MESH:D005334
299 9228-9242 Disease denotes conjunctivitis MESH:D003231
300 9273-9278 Disease denotes fever MESH:D005334
301 9407-9419 Disease denotes Episcleritis MESH:D015423
314 10018-10029 Species denotes Coronavirus Tax:11118
315 10200-10210 Species denotes SARS-CoV-2 Tax:2697049
316 10272-10282 Species denotes SARS-CoV-2 Tax:2697049
317 10389-10397 Species denotes patients Tax:9606
318 10505-10512 Species denotes patient Tax:9606
319 10685-10693 Species denotes patients Tax:9606
320 10979-10987 Species denotes patients Tax:9606
321 10153-10167 Disease denotes conjunctivitis MESH:D003231
322 10380-10388 Disease denotes COVID-19 MESH:C000657245
323 10544-10558 Disease denotes conjunctivitis MESH:D003231
324 10699-10713 Disease denotes conjunctivitis MESH:D003231
325 10996-11010 Disease denotes conjunctivitis MESH:D003231
328 11095-11103 Species denotes patients Tax:9606
329 11086-11094 Disease denotes COVID-19 MESH:C000657245
338 11300-11303 Gene denotes CRP Gene:1401
339 11305-11308 Gene denotes PCT Gene:796
340 11270-11273 Gene denotes age Gene:5973
341 11219-11227 Species denotes patients Tax:9606
342 11354-11362 Species denotes patients Tax:9606
343 11213-11218 Disease denotes COVID MESH:C000657245
344 11245-11263 Disease denotes ocular abnormality MESH:D005124
345 11275-11280 Disease denotes fever MESH:D005334
353 11806-11809 Gene denotes CRP Gene:1401
354 11815-11818 Gene denotes PCT Gene:796
355 11966-11974 Species denotes patients Tax:9606
356 11534-11554 Disease denotes SARS-CoV-2 infection MESH:C000657245
357 11675-11690 Disease denotes viral infection MESH:D001102
358 11870-11879 Disease denotes infection MESH:D007239
359 11901-11921 Disease denotes SARS-CoV-2 infection MESH:C000657245
369 12038-12056 Gene denotes C-reactive protein Gene:1401
370 12174-12177 Gene denotes CRP Gene:1401
371 12232-12235 Gene denotes CRP Gene:1401
372 12443-12446 Gene denotes CRP Gene:1401
373 12361-12369 Species denotes patients Tax:9606
374 12100-12112 Disease denotes inflammation MESH:D007249
375 12218-12230 Disease denotes inflammation MESH:D007249
376 12303-12315 Disease denotes lung lesions MESH:D008171
377 12352-12360 Disease denotes COVID-19 MESH:C000657245
395 13172-13184 Gene denotes interferon-γ Gene:3458
396 13152-13155 Gene denotes PCT Gene:796
397 13043-13046 Gene denotes PCT Gene:796
398 12856-12859 Gene denotes PCT Gene:796
399 12686-12689 Gene denotes PCT Gene:796
400 13302-13310 Species denotes patients Tax:9606
401 13548-13556 Species denotes patients Tax:9606
402 13599-13607 Species denotes patients Tax:9606
403 12881-12888 Species denotes patient Tax:9606
404 13246-13249 Gene denotes PCT Gene:796
405 13519-13533 Chemical denotes Procalcitonine
406 12710-12730 Disease denotes bacterial infections MESH:D001424
407 12756-12772 Disease denotes viral infections MESH:D001102
408 12921-12933 Disease denotes inflammation MESH:D007249
409 13223-13239 Disease denotes viral infections MESH:D001102
410 13331-13351 Disease denotes SARS-CoV-2 infection MESH:C000657245
411 13453-13464 Disease denotes coinfection MESH:D060085
417 14058-14061 Gene denotes CRP Gene:1401
418 13719-13727 Species denotes Patients Tax:9606
419 13907-13919 Disease denotes inflammation MESH:D007249
420 14022-14034 Disease denotes inflammation MESH:D007249
421 14038-14047 Disease denotes infection MESH:D007239
426 14211-14214 Gene denotes age Gene:5973
427 14095-14103 Species denotes patients Tax:9606
428 14285-14300 Disease denotes dry eye disease MESH:D015352
429 14302-14329 Disease denotes meibomian gland dysfunction MESH:D000080343
437 14859-14862 Gene denotes CRP Gene:1401
438 14864-14867 Gene denotes PCT Gene:796
439 14577-14587 Species denotes SARS-CoV-2 Tax:2697049
440 14773-14781 Species denotes patients Tax:9606
441 14743-14751 Disease denotes COVID-19 MESH:C000657245
442 14787-14795 Disease denotes COVID-19 MESH:C000657245
443 15024-15029 Disease denotes fever MESH:D005334
447 15233-15241 Species denotes patients Tax:9606
448 15057-15072 Disease denotes Lymphocytopenia MESH:D008231
449 15204-15212 Disease denotes COVID-19 MESH:C000657245
453 15585-15593 Species denotes patients Tax:9606
454 15599-15607 Disease denotes COVID-19 MESH:C000657245
455 15900-15908 Disease denotes COVID-19 MESH:C000657245
460 15916-15919 Gene denotes age Gene:5973
461 16119-16127 Species denotes patients Tax:9606
462 15921-15931 Disease denotes high fever MESH:D005334
463 16394-16402 Disease denotes COVID-19 MESH:C000657245
465 16479-16487 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 207-225 Body_part denotes respiratory system http://purl.org/sig/ont/fma/fma7158
T2 1341-1351 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T3 1453-1463 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T4 1740-1750 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T5 1751-1761 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T6 2706-2724 Body_part denotes respiratory system http://purl.org/sig/ont/fma/fma7158
T7 2747-2752 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T8 3004-3021 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T9 3067-3090 Body_part denotes gastrointestinal system http://purl.org/sig/ont/fma/fma71132
T10 3102-3109 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T11 3237-3250 Body_part denotes bronchiolitis http://purl.org/sig/ont/fma/fma76497
T12 3324-3327 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T13 3346-3350 Body_part denotes tear http://purl.org/sig/ont/fma/fma59756
T14 3421-3426 Body_part denotes tears http://purl.org/sig/ont/fma/fma59756
T15 3456-3467 Body_part denotes conjunctiva http://purl.org/sig/ont/fma/fma59011
T16 3567-3584 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T17 3597-3614 Body_part denotes nasolacrimal duct http://purl.org/sig/ont/fma/fma9703
T18 3653-3667 Body_part denotes lacrimal gland http://purl.org/sig/ont/fma/fma59101
T19 3920-3927 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T20 4928-4934 Body_part denotes thorax http://purl.org/sig/ont/fma/fma9576
T21 5119-5125 Body_part denotes thorax http://purl.org/sig/ont/fma/fma9576
T22 5162-5172 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T23 5174-5184 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T24 5189-5197 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T25 5217-5224 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T26 5236-5246 Body_part denotes calcitonin http://purl.org/sig/ont/fma/fma83348
T27 5254-5265 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T28 6829-6835 Body_part denotes thorax http://purl.org/sig/ont/fma/fma9576
T29 7245-7255 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T30 7263-7273 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T31 7277-7287 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T32 7397-7407 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T33 7546-7554 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T34 7881-7891 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T35 7938-7948 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T36 7994-8004 Body_part denotes Neutrophil http://purl.org/sig/ont/fma/fma62860
T37 8005-8015 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T38 8051-8059 Body_part denotes Monocyte http://purl.org/sig/ont/fma/fma62864
T39 8378-8385 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T40 8395-8405 Body_part denotes calcitonin http://purl.org/sig/ont/fma/fma83348
T41 8411-8422 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T42 8779-8789 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T43 8793-8803 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T44 9297-9307 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T45 9586-9594 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T46 10341-10345 Body_part denotes tear http://purl.org/sig/ont/fma/fma59756
T47 10657-10661 Body_part denotes tear http://purl.org/sig/ont/fma/fma59756
T48 10666-10677 Body_part denotes conjunctiva http://purl.org/sig/ont/fma/fma59011
T49 10728-10732 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T50 10793-10797 Body_part denotes tear http://purl.org/sig/ont/fma/fma59756
T51 10932-10937 Body_part denotes tears http://purl.org/sig/ont/fma/fma59756
T52 10942-10953 Body_part denotes conjunctiva http://purl.org/sig/ont/fma/fma59011
T53 11282-11292 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T54 11402-11412 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T55 12049-12056 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T56 12159-12164 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T57 12303-12307 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T58 12571-12581 Body_part denotes calcitonin http://purl.org/sig/ont/fma/fma83348
T59 12605-12609 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 12614-12623 Body_part denotes intestine http://purl.org/sig/ont/fma/fma7199
T61 12661-12670 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T62 12891-12896 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T63 13816-13827 Body_part denotes Erythrocyte http://purl.org/sig/ont/fma/fma62845
T64 14245-14252 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T65 14289-14292 Body_part denotes eye http://purl.org/sig/ont/fma/fma54448
T66 14302-14317 Body_part denotes meibomian gland http://purl.org/sig/ont/fma/fma59104
T67 14553-14558 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T68 14625-14633 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T69 15097-15108 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T70 15254-15264 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T71 15268-15278 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T72 15943-15953 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T73 15954-15964 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T74 16217-16222 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 207-225 Body_part denotes respiratory system http://purl.obolibrary.org/obo/UBERON_0001004
T2 296-302 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T3 2706-2724 Body_part denotes respiratory system http://purl.obolibrary.org/obo/UBERON_0001004
T4 2747-2752 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T5 3004-3021 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T6 3456-3467 Body_part denotes conjunctiva http://purl.obolibrary.org/obo/UBERON_0001811
T7 3567-3584 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T8 3597-3614 Body_part denotes nasolacrimal duct http://purl.obolibrary.org/obo/UBERON_0002392
T9 3610-3614 Body_part denotes duct http://purl.obolibrary.org/obo/UBERON_0000058
T10 3653-3667 Body_part denotes lacrimal gland http://purl.obolibrary.org/obo/UBERON_0001817
T11 3653-3661 Body_part denotes lacrimal http://purl.obolibrary.org/obo/UBERON_3010146
T12 3662-3667 Body_part denotes gland http://purl.obolibrary.org/obo/UBERON_0002530
T13 10666-10677 Body_part denotes conjunctiva http://purl.obolibrary.org/obo/UBERON_0001811
T14 10728-10732 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T15 10942-10953 Body_part denotes conjunctiva http://purl.obolibrary.org/obo/UBERON_0001811
T16 12159-12164 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T17 12303-12307 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T18 12605-12609 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T19 12614-12623 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T20 12891-12896 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T21 14289-14292 Body_part denotes eye http://purl.obolibrary.org/obo/UBERON_0000970
T22 14312-14317 Body_part denotes gland http://purl.obolibrary.org/obo/UBERON_0002530
T23 14553-14558 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T24 16217-16222 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 25-49 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T2 68-92 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 94-102 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 164-172 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 423-431 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 699-707 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 856-864 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1102-1110 Disease denotes epiphora http://purl.obolibrary.org/obo/MONDO_0001793
T9 1178-1192 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T10 1403-1406 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T12 1909-1918 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T13 2080-2127 Disease denotes Severe Acute Respiratory Syndrome Coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T14 2129-2137 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T15 2174-2198 Disease denotes Coronavirus Disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T16 2200-2208 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 2497-2505 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 2679-2687 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 2920-2928 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 2945-2953 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 2986-3021 Disease denotes infections in the respiratory tract http://purl.obolibrary.org/obo/MONDO_0024355
T22 3132-3140 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T23 3218-3232 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T24 3237-3250 Disease denotes bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T25 3315-3323 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 3548-3557 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T27 3636-3645 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T28 3767-3775 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 3780-3788 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 4045-4053 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 4162-4170 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 4697-4705 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 4725-4733 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 4900-4908 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 4963-4978 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T36 4969-4978 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T37 4989-4997 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 5248-5251 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T40 5338-5340 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T41 6219-6227 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 6437-6445 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T43 6895-6899 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T44 6906-6915 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T45 6954-6958 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T46 6965-6974 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T47 7088-7092 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T48 7099-7108 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T49 7300-7303 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T51 7567-7569 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T52 8142-8145 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T54 8271-8273 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T55 8387-8390 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T57 8470-8472 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T58 8680-8684 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T59 8691-8700 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T60 8752-8755 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T62 8829-8837 Disease denotes Epiphora http://purl.obolibrary.org/obo/MONDO_0001793
T63 9032-9035 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T65 9180-9183 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T67 9228-9242 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T68 9365-9368 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T70 9480-9483 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T72 9571-9573 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T73 9716-9724 Disease denotes Epiphora http://purl.obolibrary.org/obo/MONDO_0001793
T74 9795-9809 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T75 10153-10167 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T76 10200-10208 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 10272-10280 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 10380-10388 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T79 10544-10558 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T80 10699-10713 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T81 10996-11010 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T82 11086-11094 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T83 11305-11308 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T85 11534-11542 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T86 11545-11554 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T87 11675-11690 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T88 11681-11690 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T89 11815-11818 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T91 11870-11879 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T92 11901-11909 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T93 11912-11921 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T94 12100-12112 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T95 12218-12230 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T96 12352-12360 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 12686-12689 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T99 12710-12730 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T100 12756-12772 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T101 12856-12859 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T103 12921-12933 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T104 13043-13046 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T106 13152-13155 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T108 13223-13239 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T109 13246-13249 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T111 13331-13339 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 13342-13351 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T113 13907-13919 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T114 14022-14034 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T115 14038-14047 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T116 14285-14292 Disease denotes dry eye http://purl.obolibrary.org/obo/MONDO_0006733
T117 14342-14353 Disease denotes infestation http://purl.obolibrary.org/obo/MONDO_0005135
T118 14577-14585 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 14743-14751 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 14787-14795 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 14864-14867 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T123 15057-15072 Disease denotes Lymphocytopenia http://purl.obolibrary.org/obo/MONDO_0003783
T124 15204-15212 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 15599-15607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 15900-15908 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 16394-16402 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 16479-16487 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 182-192 http://purl.obolibrary.org/obo/CLO_0009985 denotes is focused
T2 207-225 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory system
T3 296-302 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T4 348-349 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 891-895 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T6 891-895 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T7 917-923 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T8 1907-1908 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1938-1939 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1960-1962 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T11 1983-1984 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T12 2039-2047 http://purl.obolibrary.org/obo/OBI_0100026 denotes organism
T13 2039-2047 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organism
T14 2252-2264 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T15 2291-2292 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 2437-2443 http://purl.obolibrary.org/obo/NCBITaxon_9005 denotes Turkey
T17 2478-2480 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T18 2506-2509 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T19 2530-2531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 2560-2566 http://purl.obolibrary.org/obo/NCBITaxon_9005 denotes Turkey
T21 2695-2702 http://purl.obolibrary.org/obo/CLO_0009985 denotes focuses
T22 2706-2724 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory system
T23 2747-2752 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T24 2878-2884 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T25 3237-3250 http://purl.obolibrary.org/obo/UBERON_0002186 denotes bronchiolitis
T26 3397-3402 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T27 3456-3467 http://purl.obolibrary.org/obo/UBERON_0001811 denotes conjunctiva
T28 3456-3467 http://www.ebi.ac.uk/efo/EFO_0000374 denotes conjunctiva
T29 3610-3614 http://purl.obolibrary.org/obo/UBERON_0000025 denotes duct
T30 3610-3614 http://purl.obolibrary.org/obo/UBERON_0000058 denotes duct
T31 3662-3667 http://purl.obolibrary.org/obo/UBERON_0002530 denotes gland
T32 3662-3667 http://www.ebi.ac.uk/efo/EFO_0000797 denotes gland
T33 3725-3726 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 3874-3875 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T35 3884-3885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 3928-3931 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T37 4061-4063 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T38 4359-4365 http://purl.obolibrary.org/obo/NCBITaxon_9005 denotes Turkey
T39 4928-4934 http://www.ebi.ac.uk/efo/EFO_0000965 denotes thorax
T40 5119-5125 http://www.ebi.ac.uk/efo/EFO_0000965 denotes thorax
T41 5189-5197 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T42 5254-5265 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T43 5672-5673 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 5833-5835 http://purl.obolibrary.org/obo/CLO_0009877 denotes NY
T45 5898-5904 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T46 5931-5935 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T47 5973-5979 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T48 6000-6004 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T49 6058-6064 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T50 6089-6093 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T51 6095-6098 http://purl.obolibrary.org/obo/CLO_0001547 denotes A p
T52 6292-6296 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T53 6292-6296 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T54 6317-6323 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T55 6417-6423 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T56 6590-6592 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T57 6829-6835 http://www.ebi.ac.uk/efo/EFO_0000965 denotes thorax
T58 7546-7554 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T59 8051-8059 http://purl.obolibrary.org/obo/CL_0000576 denotes Monocyte
T60 8411-8422 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T61 9586-9594 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T62 10037-10040 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T63 10101-10103 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T64 10116-10117 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 10301-10302 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T66 10438-10443 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T67 10474-10479 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T68 10631-10636 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T69 10666-10677 http://purl.obolibrary.org/obo/UBERON_0001811 denotes conjunctiva
T70 10666-10677 http://www.ebi.ac.uk/efo/EFO_0000374 denotes conjunctiva
T71 10942-10953 http://purl.obolibrary.org/obo/UBERON_0001811 denotes conjunctiva
T72 10942-10953 http://www.ebi.ac.uk/efo/EFO_0000374 denotes conjunctiva
T73 11484-11485 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74 11593-11599 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T75 12029-12031 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T76 12117-12120 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T77 12121-12122 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 12198-12199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T79 12211-12217 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T80 12303-12307 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T81 12303-12307 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T82 12473-12479 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T83 12548-12549 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 12550-12557 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T85 12605-12609 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T86 12605-12609 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T87 12614-12623 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestine
T88 12614-12623 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestine
T89 12787-12788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 12841-12843 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T91 12900-12903 http://purl.obolibrary.org/obo/CLO_0001313 denotes 3–6
T92 12961-12963 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T93 12984-12986 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T94 12989-12990 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T95 13109-13110 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 13441-13442 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 13816-13827 http://purl.obolibrary.org/obo/CL_0000232 denotes Erythrocyte
T98 13932-13933 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 14289-14292 http://www.ebi.ac.uk/efo/EFO_0000827 denotes eye
T100 14312-14317 http://purl.obolibrary.org/obo/UBERON_0002530 denotes gland
T101 14312-14317 http://www.ebi.ac.uk/efo/EFO_0000797 denotes gland
T102 14527-14529 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T103 14553-14558 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T104 14588-14593 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T105 14889-14890 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 14905-14911 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T107 15184-15185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 15560-15561 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T109 15816-15817 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 16217-16222 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T111 16317-16318 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 891-895 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T2 1628-1633 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T3 4005-4015 Chemical denotes ophthalmic http://purl.obolibrary.org/obo/CHEBI_66981
T4 4911-4923 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T5 4919-4923 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T6 5217-5224 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7 5236-5246 Chemical denotes calcitonin http://purl.obolibrary.org/obo/CHEBI_3306
T8 5292-5299 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T9 5321-5329 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T11 5833-5835 Chemical denotes NY http://purl.obolibrary.org/obo/CHEBI_73427
T12 6292-6296 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T13 8378-8385 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T14 8395-8405 Chemical denotes calcitonin http://purl.obolibrary.org/obo/CHEBI_3306
T15 8447-8454 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T16 8473-8481 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T18 12049-12056 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T19 12550-12557 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T20 12571-12581 Chemical denotes calcitonin http://purl.obolibrary.org/obo/CHEBI_3306
T21 12650-12656 Chemical denotes toxins http://purl.obolibrary.org/obo/CHEBI_27026
T22 13172-13182 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T23 15226-15231 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 1130-1139 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T2 4784-4797 http://purl.obolibrary.org/obo/GO_0003968 denotes transcriptase
T3 4784-4797 http://purl.obolibrary.org/obo/GO_0003899 denotes transcriptase
T4 8852-8861 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T5 9745-9754 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T6 9966-9972 http://purl.obolibrary.org/obo/GO_0007601 denotes vision
T7 10363-10373 http://purl.obolibrary.org/obo/GO_0046903 denotes secretions
T8 10815-10824 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T9 11459-11480 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T10 11675-11690 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T11 12100-12112 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T12 12218-12230 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T13 12473-12501 http://purl.obolibrary.org/obo/GO_0050729 denotes active inflammatory response
T14 12480-12501 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T15 12756-12772 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T16 12921-12933 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T17 13223-13239 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T18 13907-13919 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T19 14022-14034 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T20 14536-14548 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T21 14661-14686 http://purl.obolibrary.org/obo/GO_0002456 denotes cellular immune responses
T22 14661-14686 http://purl.obolibrary.org/obo/GO_0002449 denotes cellular immune responses
T23 14661-14686 http://purl.obolibrary.org/obo/GO_0002443 denotes cellular immune responses
T24 14912-14927 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T25 15437-15458 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response

2_test

Id Subject Object Predicate Lexical cue
32504100-31986257-45244937 1979-1980 31986257 denotes 1
32504100-29551135-45244938 2957-2958 29551135 denotes 4
32504100-15205225-45244939 3111-3112 15205225 denotes 5
32504100-32087098-45244940 3114-3115 32087098 denotes 6
32504100-16102311-45244941 3289-3290 16102311 denotes 7
32504100-15205225-45244942 3428-3429 15205225 denotes 5
32504100-15205225-45244943 3684-3685 15205225 denotes 5
32504100-32035510-45244944 10081-10083 32035510 denotes 13
32504100-17934713-45244945 11881-11883 17934713 denotes 17
32504100-32298988-45244946 12033-12035 32298988 denotes 19
32504100-9971870-45244947 12143-12145 9971870 denotes 20
32504100-10984072-45244948 12841-12843 10984072 denotes 22
32504100-10984072-45244949 12984-12986 10984072 denotes 22
32504100-30697132-45244950 13241-13243 30697132 denotes 24
32504100-11462193-45244951 14084-14086 11462193 denotes 25
32504100-28466096-45244952 14753-14755 28466096 denotes 29
T47972 1979-1980 31986257 denotes 1
T80329 2957-2958 29551135 denotes 4
T20185 3111-3112 15205225 denotes 5
T36971 3114-3115 32087098 denotes 6
T38813 3289-3290 16102311 denotes 7
T58267 3428-3429 15205225 denotes 5
T25633 3684-3685 15205225 denotes 5
T22104 10081-10083 32035510 denotes 13
T68090 11881-11883 17934713 denotes 17
T19022 12033-12035 32298988 denotes 19
T57918 12143-12145 9971870 denotes 20
T11313 12841-12843 10984072 denotes 22
T54217 12984-12986 10984072 denotes 22
T96503 13241-13243 30697132 denotes 24
T32476 14084-14086 11462193 denotes 25
T62086 14753-14755 28466096 denotes 29

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1102-1110 Phenotype denotes epiphora http://purl.obolibrary.org/obo/HP_0009926
T2 1149-1157 Phenotype denotes chemosis http://purl.obolibrary.org/obo/HP_0012375
T3 1178-1192 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T4 1206-1218 Phenotype denotes episcleritis http://purl.obolibrary.org/obo/HP_0100534
T5 1256-1267 Phenotype denotes photophobia http://purl.obolibrary.org/obo/HP_0000613
T6 1583-1588 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T7 1723-1728 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T8 1909-1918 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T9 3218-3232 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T10 3237-3250 Phenotype denotes bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T11 4969-4978 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T12 5096-5101 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T13 5422-5427 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T14 6583-6588 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T15 6614-6619 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T16 6643-6663 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T17 6687-6695 Phenotype denotes headache http://purl.obolibrary.org/obo/HP_0002315
T18 6814-6835 Phenotype denotes abnormality at thorax http://purl.obolibrary.org/obo/HP_0000765
T19 6906-6915 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T20 6965-6974 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T21 7041-7061 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T22 7099-7108 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T23 7152-7157 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T24 7604-7609 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T25 7830-7835 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T26 8628-8633 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T27 8691-8700 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T28 8714-8722 Phenotype denotes high ESR http://purl.obolibrary.org/obo/HP_0003565
T29 8829-8837 Phenotype denotes Epiphora http://purl.obolibrary.org/obo/HP_0009926
T30 8900-8905 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T31 8944-8952 Phenotype denotes high ESR http://purl.obolibrary.org/obo/HP_0003565
T32 9118-9126 Phenotype denotes Chemosis http://purl.obolibrary.org/obo/HP_0012375
T33 9228-9242 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T34 9273-9278 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T35 9407-9419 Phenotype denotes Episcleritis http://purl.obolibrary.org/obo/HP_0100534
T36 9716-9724 Phenotype denotes Epiphora http://purl.obolibrary.org/obo/HP_0009926
T37 9765-9773 Phenotype denotes Chemosis http://purl.obolibrary.org/obo/HP_0012375
T38 9795-9809 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T39 9820-9832 Phenotype denotes Episcleritis http://purl.obolibrary.org/obo/HP_0100534
T40 9859-9870 Phenotype denotes Photophobia http://purl.obolibrary.org/obo/HP_0000613
T41 9958-9972 Phenotype denotes Blurred vision http://purl.obolibrary.org/obo/HP_0000622
T42 10153-10167 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T43 10544-10558 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T44 10699-10713 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T45 10996-11010 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T46 11275-11280 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T47 14289-14300 Phenotype denotes eye disease http://purl.obolibrary.org/obo/HP_0000478
T48 14302-14329 Phenotype denotes meibomian gland dysfunction http://purl.obolibrary.org/obo/HP_0025610
T49 14625-14639 Phenotype denotes Cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T50 15024-15029 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T51 15057-15072 Phenotype denotes Lymphocytopenia http://purl.obolibrary.org/obo/HP_0001888
T52 15926-15931 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-49 Sentence denotes Ocular manifestations of coronavirus disease 2019
T2 51-59 Sentence denotes Abstract
T3 60-67 Sentence denotes Purpose
T4 68-262 Sentence denotes Coronavirus disease 2019 (COVID-19) is an ongoing global public health problem, and most of the COVID-19 research is focused mainly on the respiratory system because of life-threatening results.
T5 263-371 Sentence denotes However, manifestations in other organs should not be ignored since they can also be a mode of transmission.
T6 372-541 Sentence denotes We sought to describe the ocular manifestations of COVID-19 and investigate the association between ocular involvement and clinical presentation and laboratory outcomes.
T7 543-550 Sentence denotes Methods
T8 551-634 Sentence denotes This cross-sectional study was conducted between March 1, 2020, and April 30, 2020.
T9 635-744 Sentence denotes Ninety-three sequentially hospitalized and clinically confirmed COVID-19 patients were included in the study.
T10 745-836 Sentence denotes The systemic and ocular symptoms, clinical findings, and laboratory outcomes were recorded.
T11 838-845 Sentence denotes Results
T12 846-924 Sentence denotes Of the 93 COVID-19 patients, 54 (58.1%) were male, and 39 (41.9%) were female.
T13 925-988 Sentence denotes Mean age of the patients was 39.4 ± 21.9 (min 7, max 88) years.
T14 989-1051 Sentence denotes Twenty patients (n 21.5%) had at least one ocular abnormality.
T15 1052-1227 Sentence denotes Most common findings included hyperemia (n = 20), epiphora (n = 9), increased secretion (n = 6), chemosis (n = 3), follicular conjunctivitis (n = 2), and episcleritis (n = 2).
T16 1228-1275 Sentence denotes The most common symptom was photophobia (n 15).
T17 1276-1447 Sentence denotes Patients with ocular involvement were more likely to have higher neutrophil counts (p = 0.001), and increased CRP (p < 0.001), PCT (p = 0.001), and ESR levels (p < 0.001).
T18 1448-1545 Sentence denotes Mean lymphocyte count was statistically lower in patients with ocular manifestations (p = 0.001).
T19 1546-1694 Sentence denotes Mean age and number of patients with fever over 37.3 °C in the ocular involvement group was found to be higher (p < 0.001, p = 0.006, respectively).
T20 1696-1706 Sentence denotes Conclusion
T21 1707-1859 Sentence denotes Older age, high fever, increased neutrophil/lymphocyte ratio, and high levels of acute phase reactants seemed to be risk factors for ocular involvement.
T22 1861-1873 Sentence denotes Introduction
T23 1874-1982 Sentence denotes In December 2019, China reported a pneumonia outbreak in Wuhan, a city with more than 11 million people [1].
T24 1983-2214 Sentence denotes A new coronavirus (COV) was identified as the causative organism—namely, novel coronavirus, nCOV-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)—and the disease was named as the Coronavirus Disease 2019 (COVID-19) [2].
T25 2215-2418 Sentence denotes After its introduction, World Health Organization declared the situation as a public health emergency of international concern and published suggestions for protection and prevention of transmission [3].
T26 2419-2487 Sentence denotes The first case in Turkey was officially announced on March 11, 2020.
T27 2488-2594 Sentence denotes To date, COVID-19 has confirmed to affect a total of 115000 patients in Turkey with more than 3000 deaths.
T28 2595-2725 Sentence denotes Due to the life-threatening nature of its complications, most of the research about COVID-19 mainly focuses on respiratory system.
T29 2726-2837 Sentence denotes However, since other organ involvements might be alternative routes of transmissions, they must not be ignored.
T30 2838-2885 Sentence denotes Seven types of CoVs are known to infect humans:
T31 2886-2960 Sentence denotes 229E, NL63, OC 43, HKU, MERS-CoV, SARS-CoV, and the recent SARS-CoV-2 [4].
T32 2961-3117 Sentence denotes Most of these CoVs cause infections in the respiratory tract but also known to have manifestations in the gastrointestinal system and ocular tissues [5, 6].
T33 3118-3179 Sentence denotes HCoV-NL63 and SARS-CoV are known to affect the ocular system.
T34 3180-3292 Sentence denotes There have been reports of cases with conjunctivitis and bronchiolitis between 2000 and 2003 with HCoV-NL63 [7].
T35 3293-3431 Sentence denotes In addition, in 2004, SARS-CoV-RNA was identified in tear samples of three patients suggesting that the virus can be present in tears [5].
T36 3432-3687 Sentence denotes Theories, including the conjunctiva being the direct inoculation site of pathogen-loaded droplets, migration of the infection from the respiratory tract through the nasolacrimal duct or even hematogenous infection of the lacrimal gland, were proposed [5].
T37 3688-3870 Sentence denotes Genomic and structural analyses show a similar receptor-binding motive between SARS-CoV and SARS-CoV-2 with resembling pathologic features and epidemiological characteristics [8, 9].
T38 3871-3947 Sentence denotes As a result, a similar involvement of the ocular tissues has been suspected.
T39 3948-4065 Sentence denotes Nevertheless, there have only been few reports about the ophthalmic manifestations of the recent SARS-CoV-2 [10, 11].
T40 4066-4251 Sentence denotes The purpose of our study is to investigate ocular findings and symptoms of clinically confirmed COVID-19 patients and assess the relationship with those findings and laboratory results.
T41 4253-4274 Sentence denotes Materials and methods
T42 4275-4439 Sentence denotes This cross-sectional study was conducted at the Kars Harakani State Hospital, Kars, Turkey, in accordance with the ethical standards of the Declaration of Helsinki.
T43 4440-4555 Sentence denotes The study protocol was approved by the institutional board of the Okan University Medical Faculty ethics committee.
T44 4556-4720 Sentence denotes Between March 11th and April 30th, 2020, 93 consecutive patients who were hospitalized in Kars Harakani State Hospital with the diagnosis of COVID-19 were included.
T45 4721-4984 Sentence denotes The COVID-19 diagnosis was made according to real time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of respiratory specimens which revealed positive results for SARS-CoV-2 nucleic acid and thorax CT findings consistent with viral pneumonia [12].
T46 4985-5073 Sentence denotes The COVID-19 diagnosis was confirmed with RT-PCR in all included patients in this study.
T47 5074-5376 Sentence denotes The patient symptoms, fever at presentation, thorax computerized tomography (CT) scans, neutrophil, lymphocyte and monocyte counts, C-reactive protein (CRP), pro-calcitonin (PCT), erythrocyte sedimentation rate (ESR), lactate dehydrogenase (LDH), creatine kinase (CK), and d-dimer levels were recorded.
T48 5377-5421 Sentence denotes Older age was accepted as 65 years or older.
T49 5422-5464 Sentence denotes Fever was classified as 37.3 °C or higher.
T50 5465-5531 Sentence denotes Ocular findings and symptoms were evaluated at hospital admission.
T51 5532-5708 Sentence denotes Ophthalmological examination including ocular surface and anterior segment assessment was performed by the same experienced clinician using a binocular indirect ophthalmoscope.
T52 5709-5752 Sentence denotes Ocular symptoms and findings were recorded.
T53 5753-5847 Sentence denotes Statistical analyses were performed with SPSS Statistics (Version 22.0, Armonk, NY: IBM Corp).
T54 5848-5936 Sentence denotes The assumption of normal distribution of data was tested by the Kolmogorov-Smirnov test.
T55 5937-6005 Sentence denotes Association of descriptive data was tested with the chi-square test.
T56 6006-6094 Sentence denotes Differences in the outcomes between the groups were tested with the Mann–Whitney U test.
T57 6095-6161 Sentence denotes A p value less than 0.05 was considered statistically significant.
T58 6163-6170 Sentence denotes Results
T59 6171-6255 Sentence denotes Ninety-three patients with clinically confirmed COVID-19 were included in the study.
T60 6256-6324 Sentence denotes Of the 93 patients, 54 (58.1%) were male and 39 (41.9%) were female.
T61 6325-6388 Sentence denotes Mean age of the patients was 39.4 ± 21.9 (min 7, max 88) years.
T62 6389-6554 Sentence denotes Ninety-two patients (98.9%) tested positive for SARS-CoV-2 by RT-PCR of nasopharyngeal swabs; while 1 (1.1%) was positive in the RT-PCR of the endotracheal aspirate.
T63 6555-6769 Sentence denotes Twenty (21.5%) patients had fever, 18 (19.4%) patients had cough, 3 (3.2%) patients had respiratory distress, 2 (2.2%) patients had headache, and 50 (53.8%) patients had no symptoms at presentation to the hospital.
T64 6770-7004 Sentence denotes Fifty-eight (62.4%) patients had no sign of abnormality at thorax CT, whereas 23 (24.7%) patients had typical CT findings of SARS CoV-2 pneumonia, and 12 (12.9%) patients had possible SARS CoV-2 pneumonia according to the CT findings.
T65 7005-7127 Sentence denotes Five patients were intubated due to respiratory distress and 4 of them died due to SARS CoV-2 pneumonia and comorbidities.
T66 7128-7239 Sentence denotes Table 1 represents age, fever, and the laboratory findings of the patients with and without ocular involvement.
T67 7240-7438 Sentence denotes Mean neutrophil count, neutrophil to lymphocyte ratio, CRP, PCT, and ESR levels were significantly higher in patients with ocular involvement; whereas, mean lymphocyte count was significantly lower.
T68 7439-7590 Sentence denotes No significant difference was observed between patients with and without ocular involvement regarding mean monocyte count, LDH, CK, and d-dimer levels.
T69 7591-7690 Sentence denotes Table 1 Age, fever, and the laboratory findings of the patients with and without ocular involvement
T70 7691-7785 Sentence denotes Patients with ocular involvement (n = 20) Patients without ocular involvement (n = 73) P value
T71 7786-7829 Sentence denotes Age (years) 60.7 ± 19.8 33.6 ± 18.6 <0.001*
T72 7830-7880 Sentence denotes Fever over 37.3 °C (n) 12 (60.0%) 8 (11.0%) 0.006*
T73 7881-7937 Sentence denotes Neutrophil (/mm3) 6453.0 ± 4856.7 3662.2 ± 2132.3 0.001*
T74 7938-7993 Sentence denotes Lymphocyte (/mm3) 1368.0 ± 680.2 2246.5 ± 1173.3 0.001*
T75 7994-8050 Sentence denotes Neutrophil/lymphocyte ratio 7.5 ± 11.5 2.3 ± 2.8 <0.001*
T76 8051-8100 Sentence denotes Monocyte (/mm3) 471.5 ± 194.4 480.8 ± 207.5 0.918
T77 8101-8141 Sentence denotes CRP (mg/L) 55.4 ± 48.6 6.1 ± 8.8 <0.001*
T78 8142-8183 Sentence denotes PCT (μg/L) 0.30 ± 0.47 0.08 ± 0.11 0.001*
T79 8184-8227 Sentence denotes ESR (mm/hr) 42.7 ± 20.6 15.1 ± 13.3 <0.001*
T80 8228-8270 Sentence denotes LDH (U/L) 308.6 ± 132.8 242.1 ± 97.6 0.094
T81 8271-8312 Sentence denotes CK (U/L) 109.7 ± 105.9 110.1 ± 97.9 0.389
T82 8313-8362 Sentence denotes d-dimer (μg/L) 1314.2 ± 611.3 789.9 ± 658.4 0.492
T83 8363-8488 Sentence denotes CRP C-reactive protein, PCT pro-calcitonin, ESR erythrocyte sedimentation rate, LDH lactate dehydrogenase, CK creatine kinase
T84 8489-8515 Sentence denotes *Statistically significant
T85 8516-8580 Sentence denotes Table 2 represents ocular findings and symptoms of the patients.
T86 8581-8828 Sentence denotes Hyperemia was found to be associated with high fever (p = 0.006), typical radiological findings of SARS CoV-2 pneumonia (p = 0.046), high ESR and CRP (p < 0.001 for all), PCT levels (p = 0.001) and neutrophil to lymphocyte ratio (NTL) (p < 0.001).
T87 8829-9117 Sentence denotes Epiphora and increased secretion were found to be associated with high fever (p = 0.012, p = 0.006, respectively), high ESR (p = 0.001, p = 0.023, respectively), CRP (p < 0.001, p = 0.001 respectively), PCT (p = 0.002, p = 0.004 respectively), and NTL (p = 0.001, p < 0.001 respectively).
T88 9118-9216 Sentence denotes Chemosis was positively correlated with high CRP (p = 0.017), PCT (p = 0.39), and NTL (p = 0.008).
T89 9217-9406 Sentence denotes Follicular conjunctivitis was also correlated with high fever (p = 0.037), high neutrophil count (p < 0.001), ESR (p = 0.001), and CRP (p < 0.001), PCT (p = 0.001) and high NTL (p = 0.001).
T90 9407-9517 Sentence denotes Episcleritis was found to be associated with higher d-dimer (p = 0.017), PCT (p = 0.045), and CRP (p = 0.020).
T91 9518-9620 Sentence denotes No ocular finding was associated with gender, LDH or CK levels, and monocyte count (p > 0.05 for all).
T92 9621-9666 Sentence denotes Table 2 Ocular manifestations of the patients
T93 9667-9676 Sentence denotes Value (n)
T94 9677-9692 Sentence denotes Ocular findings
T95 9693-9714 Sentence denotes  Hyperemia 20 (21.5%)
T96 9715-9733 Sentence denotes  Epiphora 9 (9.7%)
T97 9734-9763 Sentence denotes  Increased secretion 6 (6.5%)
T98 9764-9782 Sentence denotes  Chemosis 3 (3.2%)
T99 9783-9818 Sentence denotes  Follicular conjunctivitis 8 (8.6%)
T100 9819-9841 Sentence denotes  Episcleritis 2 (2.2%)
T101 9842-9857 Sentence denotes Ocular symptoms
T102 9858-9881 Sentence denotes  Photophobia 15 (16.1%)
T103 9882-9903 Sentence denotes  Itchiness 13 (15.7%)
T104 9904-9931 Sentence denotes  Burning sensation 7 (8.4%)
T105 9932-9956 Sentence denotes  Gritty feeling 5 (6.0%)
T106 9957-9981 Sentence denotes  Blurred vision 4 (4.8%)
T107 9983-9993 Sentence denotes Discussion
T108 9994-10089 Sentence denotes Ocular involvement with Coronavirus family has been shown in various publications [10, 13, 14].
T109 10090-10297 Sentence denotes On January 22, 2020, when a visiting doctor in Wuhan developed conjunctivitis, and later yielded positive for SARS-CoV-2, call for research on ocular transmission and involvement of SARS-CoV-2 was made [14].
T110 10298-10473 Sentence denotes In a prospective study by Xia et al. [10], tear and conjunctival secretions of 30 COVID-19 patients were collected, and the presence of the virus was evaluated by RT-PCR [10].
T111 10474-10714 Sentence denotes Virus was detected in only one patient’s conjunctival scrapes who had conjunctivitis at the time of specimen collection; therefore, it was proposed that the virus only existed in the tear and conjunctiva of the patients with conjunctivitis.
T112 10715-11015 Sentence denotes On the other hand, in the same study, it was stated that the sample volume of tear and conjunctival secretion might be insufficient for RT-PCR detection, and therefore, the possibility of viral particles’ presence in tears and conjunctiva should not be ignored in patients without conjunctivitis.[10]
T113 11016-11165 Sentence denotes In the present study, we reported the ocular findings and symptoms of COVID-19 patients and risk factors associated with those ocular manifestations.
T114 11166-11264 Sentence denotes Results of our study suggest that 20.5% of the COVID patients had at least one ocular abnormality.
T115 11265-11443 Sentence denotes Mean age, fever, neutrophil count, CRP, PCT, and ESR levels were significantly higher in patients with ocular involvement; whereas, mean lymphocyte count was significantly lower.
T116 11444-11612 Sentence denotes The aggressive inflammatory response is a significant component in the pathophysiology of SARS-CoV-2 infection, strongly implicated in the resulting airway damage [15].
T117 11613-11723 Sentence denotes Severity of the disease is reported to be not only due to the viral infection but also the host response [16].
T118 11724-11885 Sentence denotes There are many studies highlighting the role of inflammatory markers such as ESR, CRP, and PCT to predict the onset of an inflammatory process or infection [17].
T119 11886-12037 Sentence denotes In the case of SARS-CoV-2 infection, many studies demonstrated that most of the patients present with elevated levels of acute immune markers [18, 19].
T120 12038-12147 Sentence denotes C-reactive protein begins to rise within 4–6 h in settings of inflammation and has a half-life of 4–7 h [20].
T121 12148-12231 Sentence denotes Therefore, serum level of CRP is considered to be a measure of active inflammation.
T122 12232-12375 Sentence denotes CRP levels were found to be positively correlated with the diameter of lung lesions and severity of the presentation in COVID-19 patients [21].
T123 12376-12530 Sentence denotes In our study, all of the ocular findings were correlated with high CRP levels which may indicate active inflammatory response and severity of the disease.
T124 12531-12671 Sentence denotes Procalcitonin is a peptide precursor of calcitonin, released primarily by lung and intestine, in response to bacterial toxins and cytokines.
T125 12672-12845 Sentence denotes Production of PCT is amplified during bacterial infections but downregulated during viral infections which make it a particularly interesting acute inflammatory marker [22].
T126 12846-12988 Sentence denotes Levels of PCT become detectable in patient’s serum in 3–6 h after onset of inflammation and remain elevated for 12–36 h after resolution [22].
T127 12989-13133 Sentence denotes A metaanalysis of the literature suggests that serial PCT measurement may be beneficial to evaluate progression towards a more severe form [23].
T128 13134-13245 Sentence denotes The production of PCT is inhibited by interferon-γ, whose concentration increases during viral infections [24].
T129 13246-13518 Sentence denotes PCT levels remain within the reference range in several patients with noncomplicated SARS-CoV-2 infection, whereas substantially increase in the severe form of the disease, possibly secondary to a bacterial coinfection which contributes to complicate the clinical picture.
T130 13519-13718 Sentence denotes Procalcitonine levels of the patients with ocular symptoms were higher than the patients without ocular involvement, which may also be indicative for the severity of the disease in those individuals.
T131 13719-13815 Sentence denotes Patients with ocular manifestations had higher ESR levels according to the results of our study.
T132 13816-13920 Sentence denotes Erythrocyte sedimentation rate typically begins to increase within 24 h after the onset of inflammation.
T133 13921-14088 Sentence denotes ESR can be a useful tool to aid in the diagnosis and management of certain specific situations, like inflammation or infection, but like CRP it lacks specificity [25].
T134 14089-14164 Sentence denotes Elder patients seemed to be at certain risk for developing ocular symptoms.
T135 14165-14359 Sentence denotes This may be secondary to the already existing age related changes in the ocular tissues of the older population such as dry eye disease, meibomian gland dysfunction, or demodex infestation [26].
T136 14360-14531 Sentence denotes It may be expected that ocular problems would be exacerbated in older adults, where the communication between innate and adaptive immunity is known to be compromised [27].
T137 14532-14624 Sentence denotes The pathogenesis and organ manifestations of SARS-CoV-2 virus are not fully understood [28].
T138 14625-14757 Sentence denotes Cytokine storm and viral evasion of cellular immune responses are considered to have crucial roles in the severity of COVID-19 [29].
T139 14758-14961 Sentence denotes In this study, patients with COVID-19 who had ocular manifestations had significantly high levels of CRP, PCT, and ESR, perhaps as a result of the active immune response of the host and disease severity.
T140 14962-15056 Sentence denotes This may partly explain the positive association between high fever and ocular manifestations.
T141 15057-15218 Sentence denotes Lymphocytopenia and increased levels of neutrophils have been reported to reflect an enhanced inflammatory process and suggest a poor prognosis in COVID-19 [28].
T142 15219-15350 Sentence denotes In our group, patients with higher neutrophil-to-lymphocyte ratio seemed to be in higher risk for developing ocular manifestations.
T143 15351-15459 Sentence denotes This can also be secondary to the severity of the disease with generalized aggressive inflammatory response.
T144 15460-15559 Sentence denotes Limited sample size and absence of conjunctival RT-PCR evaluation are the limitations of our study.
T145 15560-15717 Sentence denotes A larger cohort study of patients with COVID-19 from multiple centers would help to further define the ocular manifestations and risk factors of the disease.
T146 15718-15909 Sentence denotes Regardless, the findings of our study are the preliminary results shared in an effort to serve as a starting platform for research into ocular involvement immunological responses of COVID-19.
T147 15910-16083 Sentence denotes Older age, high fever, increased neutrophil/lymphocyte ratio, and high levels of acute phase reactants were associated with greater risk of developing ocular manifestations.
T148 16084-16281 Sentence denotes Care must be taken when evaluating patients with those characteristics to prevent ocular complications and viral spread, since other organ involvements might be alternative routes of transmissions.
T149 16282-16415 Sentence denotes As the current pandemic continues, a better understanding of both the transmission routes and manifestations of COVID-19 will emerge.
T150 16417-16488 Sentence denotes This article is part of topical collection on Perspectives on COVID-19.
T151 16489-16505 Sentence denotes Publisher’s note
T152 16506-16624 Sentence denotes Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
T153 16626-16659 Sentence denotes Availability of Data and Material
T154 16660-16762 Sentence denotes The data supporting the findings of this study are available from the corresponding author on request.
T155 16764-16785 Sentence denotes Authors’ contribution
T156 16786-16895 Sentence denotes All authors contributed to the study conception, design, material preparation, data collection, and analysis.
T157 16896-17032 Sentence denotes The first draft of the manuscript was written by Basak Bostanci Ceran, and all authors commented on previous versions of the manuscript.
T158 17033-17084 Sentence denotes All authors read and approved the final manuscript.
T159 17086-17119 Sentence denotes Compliance with ethical standards
T160 17121-17141 Sentence denotes Conflict of Interest
T161 17142-17201 Sentence denotes The authors declare that they have no conflict of interest.
T162 17203-17218 Sentence denotes Ethics Approval
T163 17219-17246 Sentence denotes The study protocol (Number:
T164 17247-17357 Sentence denotes 91412548-899) was approved by the institutional board of the Okan University Medical Faculty ethics committee.