PMC:7272971 / 15029-15740 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"500","span":{"begin":105,"end":115},"obj":"Species"},{"id":"501","span":{"begin":119,"end":133},"obj":"Species"},{"id":"502","span":{"begin":224,"end":234},"obj":"Species"},{"id":"503","span":{"begin":349,"end":359},"obj":"Species"},{"id":"504","span":{"begin":700,"end":710},"obj":"Species"},{"id":"505","span":{"begin":257,"end":268},"obj":"Disease"},{"id":"506","span":{"begin":336,"end":347},"obj":"Disease"},{"id":"507","span":{"begin":437,"end":457},"obj":"Disease"},{"id":"508","span":{"begin":475,"end":516},"obj":"Disease"},{"id":"509","span":{"begin":627,"end":647},"obj":"Disease"}],"attributes":[{"id":"A500","pred":"tao:has_database_id","subj":"500","obj":"Tax:2697049"},{"id":"A501","pred":"tao:has_database_id","subj":"501","obj":"Tax:9544"},{"id":"A502","pred":"tao:has_database_id","subj":"502","obj":"Tax:2697049"},{"id":"A503","pred":"tao:has_database_id","subj":"503","obj":"Tax:2697049"},{"id":"A504","pred":"tao:has_database_id","subj":"504","obj":"Tax:2697049"},{"id":"A505","pred":"tao:has_database_id","subj":"505","obj":"MESH:D015431"},{"id":"A506","pred":"tao:has_database_id","subj":"506","obj":"MESH:D015431"},{"id":"A507","pred":"tao:has_database_id","subj":"507","obj":"MESH:C563620"},{"id":"A508","pred":"tao:has_database_id","subj":"508","obj":"MESH:D007239"},{"id":"A509","pred":"tao:has_database_id","subj":"509","obj":"MESH:C563620"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T182","span":{"begin":152,"end":163},"obj":"Body_part"},{"id":"T183","span":{"begin":165,"end":172},"obj":"Body_part"},{"id":"T184","span":{"begin":176,"end":183},"obj":"Body_part"},{"id":"T185","span":{"begin":245,"end":252},"obj":"Body_part"},{"id":"T186","span":{"begin":317,"end":328},"obj":"Body_part"},{"id":"T187","span":{"begin":360,"end":363},"obj":"Body_part"},{"id":"T188","span":{"begin":393,"end":404},"obj":"Body_part"},{"id":"T189","span":{"begin":437,"end":448},"obj":"Body_part"},{"id":"T190","span":{"begin":475,"end":486},"obj":"Body_part"},{"id":"T191","span":{"begin":500,"end":507},"obj":"Body_part"},{"id":"T192","span":{"begin":532,"end":535},"obj":"Body_part"},{"id":"T193","span":{"begin":564,"end":570},"obj":"Body_part"},{"id":"T194","span":{"begin":627,"end":638},"obj":"Body_part"},{"id":"T195","span":{"begin":681,"end":689},"obj":"Body_part"}],"attributes":[{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A183","pred":"fma_id","subj":"T183","obj":"http://purl.org/sig/ont/fma/fma7394"},{"id":"A184","pred":"fma_id","subj":"T184","obj":"http://purl.org/sig/ont/fma/fma7148"},{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma7394"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A187","pred":"fma_id","subj":"T187","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A191","pred":"fma_id","subj":"T191","obj":"http://purl.org/sig/ont/fma/fma7394"},{"id":"A192","pred":"fma_id","subj":"T192","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma228738"},{"id":"A194","pred":"fma_id","subj":"T194","obj":"http://purl.org/sig/ont/fma/fma59011"},{"id":"A195","pred":"fma_id","subj":"T195","obj":"http://purl.org/sig/ont/fma/fma62871"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T59","span":{"begin":152,"end":163},"obj":"Body_part"},{"id":"T60","span":{"begin":165,"end":172},"obj":"Body_part"},{"id":"T61","span":{"begin":176,"end":183},"obj":"Body_part"},{"id":"T62","span":{"begin":245,"end":252},"obj":"Body_part"},{"id":"T63","span":{"begin":317,"end":328},"obj":"Body_part"},{"id":"T64","span":{"begin":393,"end":404},"obj":"Body_part"},{"id":"T65","span":{"begin":437,"end":448},"obj":"Body_part"},{"id":"T66","span":{"begin":475,"end":486},"obj":"Body_part"},{"id":"T67","span":{"begin":500,"end":507},"obj":"Body_part"},{"id":"T68","span":{"begin":564,"end":570},"obj":"Body_part"},{"id":"T69","span":{"begin":627,"end":638},"obj":"Body_part"}],"attributes":[{"id":"A59","pred":"uberon_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A60","pred":"uberon_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/UBERON_0003126"},{"id":"A61","pred":"uberon_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/UBERON_0000945"},{"id":"A62","pred":"uberon_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/UBERON_0003126"},{"id":"A63","pred":"uberon_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A64","pred":"uberon_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A65","pred":"uberon_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A66","pred":"uberon_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"A67","pred":"uberon_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/UBERON_0003126"},{"id":"A68","pred":"uberon_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/UBERON_0000341"},{"id":"A69","pred":"uberon_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/UBERON_0001811"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T10","span":{"begin":257,"end":268},"obj":"Phenotype"},{"id":"T11","span":{"begin":336,"end":347},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0001824"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0001824"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T76","span":{"begin":105,"end":109},"obj":"Disease"},{"id":"T77","span":{"begin":224,"end":228},"obj":"Disease"},{"id":"T78","span":{"begin":349,"end":353},"obj":"Disease"},{"id":"T79","span":{"begin":700,"end":704},"obj":"Disease"}],"attributes":[{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T226","span":{"begin":23,"end":27},"obj":"http://purl.obolibrary.org/obo/CLO_0008416"},{"id":"T227","span":{"begin":23,"end":27},"obj":"http://purl.obolibrary.org/obo/CLO_0050081"},{"id":"T228","span":{"begin":43,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T229","span":{"begin":119,"end":133},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9544"},{"id":"T230","span":{"begin":134,"end":141},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9479"},{"id":"T231","span":{"begin":152,"end":163},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T232","span":{"begin":152,"end":163},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T233","span":{"begin":203,"end":209},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9479"},{"id":"T234","span":{"begin":278,"end":285},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9479"},{"id":"T235","span":{"begin":317,"end":328},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T236","span":{"begin":317,"end":328},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T237","span":{"begin":393,"end":404},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T238","span":{"begin":393,"end":404},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T239","span":{"begin":437,"end":448},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T240","span":{"begin":437,"end":448},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T241","span":{"begin":458,"end":465},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9479"},{"id":"T242","span":{"begin":475,"end":486},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T243","span":{"begin":475,"end":486},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T244","span":{"begin":517,"end":524},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"},{"id":"T245","span":{"begin":627,"end":638},"obj":"http://purl.obolibrary.org/obo/UBERON_0001811"},{"id":"T246","span":{"begin":627,"end":638},"obj":"http://www.ebi.ac.uk/efo/EFO_0000374"},{"id":"T247","span":{"begin":648,"end":654},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}

{"project":"LitCovid-sentences","denotations":[{"id":"T103","span":{"begin":0,"end":184},"obj":"Sentence"},{"id":"T104","span":{"begin":185,"end":348},"obj":"Sentence"},{"id":"T105","span":{"begin":349,"end":466},"obj":"Sentence"},{"id":"T106","span":{"begin":467,"end":607},"obj":"Sentence"},{"id":"T107","span":{"begin":608,"end":711},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, an as yet non‐peer‐reviewed paper has been made available that directly compares inoculation of SARS‐CoV‐2 of rhesus macaque monkeys via their conjunctiva, trachea or stomach. 51 While the one monkey that received SARS‐CoV‐2 via their trachea had weight loss, the two monkeys that were inoculated via their conjunctiva had no weight loss. SARS‐CoV‐2 RNA was transiently found in the conjunctiva after one day only, and only in conjunctiva‐infected monkeys. For the conjunctiva‐infected and trachea‐infected animals, viral RNA could be found in nasal and throat swabs over the course of seven days. Interestingly, the conjunctiva‐infected animal on day 14 had the highest antibody levels to SARS‐CoV‐2."}