PMC:7272971 / 13768-14415 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7272971","sourcedb":"PMC","sourceid":"7272971","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7272971","text":"Furthermore, apart from 9‐O‐acetylated sialic acid, the other co‐receptors for coronaviruses (CD209, CD26, CD13, CD66e), have been found either in fibroblasts and dendritic cells that lie in tissue under the surface corneal and conjunctival epithelial cells, or have not been reported in ocular tissues. It is possible that the 9‐O‐acetylated sialic acid associated with proteins in tears can act as a decoy receptor, binding to the viruses and preventing them binding to cell‐associated 9‐O‐acetylated sialic acid. 44 Therefore, the evidence to date suggests that coronaviruses are unlikely to bind to ocular surface cells to initiate infection.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"473","span":{"begin":94,"end":99},"obj":"Gene"},{"id":"474","span":{"begin":113,"end":118},"obj":"Gene"},{"id":"475","span":{"begin":79,"end":92},"obj":"Species"},{"id":"476","span":{"begin":566,"end":579},"obj":"Species"},{"id":"477","span":{"begin":39,"end":50},"obj":"Chemical"},{"id":"478","span":{"begin":343,"end":354},"obj":"Chemical"},{"id":"479","span":{"begin":503,"end":514},"obj":"Chemical"},{"id":"480","span":{"begin":216,"end":223},"obj":"Disease"},{"id":"481","span":{"begin":637,"end":646},"obj":"Disease"}],"attributes":[{"id":"A473","pred":"tao:has_database_id","subj":"473","obj":"Gene:30835"},{"id":"A474","pred":"tao:has_database_id","subj":"474","obj":"Gene:1048"},{"id":"A475","pred":"tao:has_database_id","subj":"475","obj":"Tax:11118"},{"id":"A476","pred":"tao:has_database_id","subj":"476","obj":"Tax:11118"},{"id":"A477","pred":"tao:has_database_id","subj":"477","obj":"MESH:D019158"},{"id":"A478","pred":"tao:has_database_id","subj":"478","obj":"MESH:D019158"},{"id":"A479","pred":"tao:has_database_id","subj":"479","obj":"MESH:D019158"},{"id":"A480","pred":"tao:has_database_id","subj":"480","obj":"MESH:D003316"},{"id":"A481","pred":"tao:has_database_id","subj":"481","obj":"MESH:D007239"},{"subj":"473","pred":"source","obj":"LitCovid-PubTator"},{"subj":"474","pred":"source","obj":"LitCovid-PubTator"},{"subj":"475","pred":"source","obj":"LitCovid-PubTator"},{"subj":"476","pred":"source","obj":"LitCovid-PubTator"},{"subj":"477","pred":"source","obj":"LitCovid-PubTator"},{"subj":"478","pred":"source","obj":"LitCovid-PubTator"},{"subj":"479","pred":"source","obj":"LitCovid-PubTator"},{"subj":"480","pred":"source","obj":"LitCovid-PubTator"},{"subj":"481","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T165","span":{"begin":147,"end":158},"obj":"Body_part"},{"id":"T166","span":{"begin":163,"end":178},"obj":"Body_part"},{"id":"T167","span":{"begin":173,"end":178},"obj":"Body_part"},{"id":"T168","span":{"begin":191,"end":197},"obj":"Body_part"},{"id":"T169","span":{"begin":228,"end":257},"obj":"Body_part"},{"id":"T170","span":{"begin":252,"end":257},"obj":"Body_part"},{"id":"T171","span":{"begin":295,"end":302},"obj":"Body_part"},{"id":"T172","span":{"begin":371,"end":379},"obj":"Body_part"},{"id":"T173","span":{"begin":383,"end":388},"obj":"Body_part"},{"id":"T174","span":{"begin":472,"end":476},"obj":"Body_part"},{"id":"T175","span":{"begin":611,"end":624},"obj":"Body_part"},{"id":"T176","span":{"begin":619,"end":624},"obj":"Body_part"}],"attributes":[{"id":"A165","pred":"fma_id","subj":"T165","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A166","pred":"fma_id","subj":"T166","obj":"http://purl.org/sig/ont/fma/fma273565"},{"id":"A167","pred":"fma_id","subj":"T167","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A168","pred":"fma_id","subj":"T168","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma70552"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma59756"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A175","pred":"fma_id","subj":"T175","obj":"http://purl.org/sig/ont/fma/fma67653"},{"id":"A176","pred":"fma_id","subj":"T176","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T168","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T53","span":{"begin":191,"end":197},"obj":"Body_part"}],"attributes":[{"id":"A53","pred":"uberon_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T71","span":{"begin":637,"end":646},"obj":"Disease"}],"attributes":[{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T206","span":{"begin":147,"end":158},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T207","span":{"begin":163,"end":178},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T208","span":{"begin":241,"end":251},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T209","span":{"begin":252,"end":257},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T210","span":{"begin":400,"end":401},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T211","span":{"begin":433,"end":440},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T212","span":{"begin":472,"end":476},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T213","span":{"begin":619,"end":624},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T206","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T207","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T208","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T209","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T210","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T211","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T212","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T213","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T60","span":{"begin":39,"end":50},"obj":"Chemical"},{"id":"T61","span":{"begin":46,"end":50},"obj":"Chemical"},{"id":"T62","span":{"begin":343,"end":354},"obj":"Chemical"},{"id":"T63","span":{"begin":350,"end":354},"obj":"Chemical"},{"id":"T64","span":{"begin":371,"end":379},"obj":"Chemical"},{"id":"T65","span":{"begin":503,"end":514},"obj":"Chemical"},{"id":"T66","span":{"begin":510,"end":514},"obj":"Chemical"}],"attributes":[{"id":"A60","pred":"chebi_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A63","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T96","span":{"begin":0,"end":303},"obj":"Sentence"},{"id":"T97","span":{"begin":304,"end":515},"obj":"Sentence"},{"id":"T98","span":{"begin":516,"end":647},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T96","pred":"source","obj":"LitCovid-sentences"},{"subj":"T97","pred":"source","obj":"LitCovid-sentences"},{"subj":"T98","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93c3","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#93ddec"},{"id":"LitCovid-PD-UBERON","color":"#ece193"},{"id":"LitCovid-PD-MONDO","color":"#c793ec"},{"id":"LitCovid-PD-CLO","color":"#93ecad"},{"id":"LitCovid-PD-CHEBI","color":"#ec9393"},{"id":"LitCovid-sentences","color":"#93adec"}]}]}}