PMC:7272971 / 13226-13767
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 451 | 414-418 | Gene | denotes | ACE2 | Gene:59272 |
| 452 | 444-451 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 453 | 455-460 | Gene | denotes | Furin | Gene:5045 |
| 454 | 497-502 | Gene | denotes | spike | Gene:43740568 |
| 455 | 536-540 | Gene | denotes | ACE2 | Gene:59272 |
| 456 | 376-386 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 457 | 388-391 | Species | denotes | SAR | Tax:2698737 |
| 458 | 392-395 | Species | denotes | CoV | Tax:11118 |
| 459 | 514-524 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 460 | 400-404 | Species | denotes | NL63 | Tax:277944 |
| 461 | 74-89 | Chemical | denotes | heparan sulfate | MESH:D006497 |
| 462 | 313-328 | Chemical | denotes | heparan sulfate | MESH:D006497 |
| 463 | 174-195 | Disease | denotes | coronavirus infection | MESH:D018352 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T160 | 74-89 | Body_part | denotes | heparan sulfate | http://purl.org/sig/ont/fma/fma63023 |
| T161 | 264-269 | Body_part | denotes | tears | http://purl.org/sig/ont/fma/fma59756 |
| T162 | 313-328 | Body_part | denotes | heparan sulfate | http://purl.org/sig/ont/fma/fma63023 |
| T163 | 461-469 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T164 | 503-510 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T68 | 186-195 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T69 | 376-380 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T70 | 514-518 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T52 | 74-89 | Chemical | denotes | heparan sulfate | http://purl.obolibrary.org/obo/CHEBI_28815 |
| T53 | 74-81 | Chemical | denotes | heparan | http://purl.obolibrary.org/obo/CHEBI_24500 |
| T54 | 82-89 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T55 | 313-328 | Chemical | denotes | heparan sulfate | http://purl.obolibrary.org/obo/CHEBI_28815 |
| T56 | 313-320 | Chemical | denotes | heparan | http://purl.obolibrary.org/obo/CHEBI_24500 |
| T57 | 321-328 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T58 | 461-469 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T59 | 503-510 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T4 | 74-89 | GlycoEpitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T5 | 313-328 | GlycoEpitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T92 | 0-137 | Sentence | denotes | In summary, the ocular surface does possess the ubiquitous viral receptor heparan sulfate, which can facilitate initial viral attachment. |
| T93 | 138-196 | Sentence | denotes | However, this is not sufficient for coronavirus infection. |
| T94 | 197-329 | Sentence | denotes | Furthermore, lactoferrin that is present in high concentrations in tears (2 mg/ml) 47 prevents viral attachment to heparan sulfate. |
| T95 | 330-541 | Sentence | denotes | 19 The ocular surface appears to possess the SARS‐CoV‐2, SAR‐CoV and NL63 receptor ACE2, but may not possess the TMPRSS2 or Furin proteins, which is required for the spike protein of SARS‐CoV‐2 to bind to ACE2. |