PMC:7271924 / 6793-7930
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T126 | 11-22 | NCBITaxon:1 | denotes | individuals |
T127 | 40-53 | GO:0005622 | denotes | intracellular |
T128 | 58-69 | GO:0051235 | denotes | sequestered |
T129 | 107-118 | CHEBI:4056;CHEBI:4056 | denotes | cytochromes |
T130 | 180-192 | CL:0000232 | denotes | erythrocytes |
T131 | 231-242 | PR:000016261 | denotes | transferrin |
T132 | 258-270 | CL:0000232 | denotes | erythrocytes |
T133 | 271-275 | GO:0019835 | denotes | lyse |
T134 | 424-429 | UBERON:0001977 | denotes | serum |
T135 | 538-549 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T136 | 614-625 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T137 | 709-717 | CHEBI:29191;CHEBI:29191 | denotes | hydroxyl |
T138 | 718-726 | CHEBI:26519;CHEBI:26519 | denotes | radicals |
T139 | 774-782 | NCBITaxon:2 | denotes | bacteria |
T140 | 834-842 | NCBITaxon:2 | denotes | bacteria |
T141 | 862-874 | GO:0051235 | denotes | sequestering |
T142 | 919-939 | NCBITaxon:139 | denotes | Borrelia burgdorferi |
T11033 | 11-22 | NCBITaxon:1 | denotes | individuals |
T96899 | 40-53 | GO:0005622 | denotes | intracellular |
T45353 | 58-69 | GO:0051235 | denotes | sequestered |
T6528 | 107-118 | CHEBI:4056;CHEBI:4056 | denotes | cytochromes |
T45565 | 180-192 | CL:0000232 | denotes | erythrocytes |
T26527 | 231-242 | PR:000016261 | denotes | transferrin |
T21144 | 258-270 | CL:0000232 | denotes | erythrocytes |
T23591 | 271-275 | GO:0019835 | denotes | lyse |
T8872 | 424-429 | UBERON:0001977 | denotes | serum |
T84052 | 538-549 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T54713 | 614-625 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T9722 | 709-717 | CHEBI:29191;CHEBI:29191 | denotes | hydroxyl |
T47741 | 718-726 | CHEBI:26519;CHEBI:26519 | denotes | radicals |
T2039 | 774-782 | NCBITaxon:2 | denotes | bacteria |
T61995 | 834-842 | NCBITaxon:2 | denotes | bacteria |
T84319 | 862-874 | GO:0051235 | denotes | sequestering |
T34249 | 919-939 | NCBITaxon:139 | denotes | Borrelia burgdorferi |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
193 | 231-242 | Gene | denotes | transferrin | Gene:7018 |
194 | 631-644 | Gene | denotes | ceruloplasmin | Gene:1356 |
195 | 648-659 | Gene | denotes | lactoferrin | Gene:280846 |
196 | 365-376 | Gene | denotes | haptoglobin | Gene:3240 |
197 | 390-399 | Gene | denotes | hemopexin | Gene:3263 |
198 | 492-505 | Gene | denotes | ceruloplasmin | Gene:1356 |
199 | 919-939 | Species | denotes | Borrelia burgdorferi | Tax:139 |
200 | 24-28 | Chemical | denotes | iron | MESH:D007501 |
201 | 206-210 | Chemical | denotes | iron | MESH:D007501 |
202 | 538-549 | Chemical | denotes | ferric iron | |
203 | 614-625 | Chemical | denotes | ferric iron | |
204 | 709-726 | Chemical | denotes | hydroxyl radicals | MESH:D017665 |
205 | 755-759 | Chemical | denotes | iron | MESH:D007501 |
206 | 875-879 | Chemical | denotes | iron | MESH:D007501 |
207 | 123-135 | Disease | denotes | FeS proteins | MESH:D018455 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T50 | 127-135 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T51 | 162-172 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T52 | 180-192 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
T53 | 258-270 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
T54 | 280-290 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T55 | 339-349 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T56 | 424-429 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T57 | 566-574 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T16 | 424-429 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T17 | 919-927 | Disease | denotes | Borrelia | http://purl.obolibrary.org/obo/MONDO_0019632 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T74 | 92-93 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T75 | 180-192 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
T76 | 258-270 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
T77 | 365-376 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | haptoglobin |
T78 | 442-455 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | ceruloplasmin |
T79 | 492-505 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | ceruloplasmin |
T80 | 517-518 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T81 | 593-594 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T82 | 631-644 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | ceruloplasmin |
T83 | 774-782 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T84 | 834-842 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T76 | 24-28 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T77 | 107-118 | Chemical | denotes | cytochromes | http://purl.obolibrary.org/obo/CHEBI_4056 |
T78 | 127-135 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T79 | 144-148 | Chemical | denotes | haem | http://purl.obolibrary.org/obo/CHEBI_30413 |
T80 | 162-172 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T81 | 206-210 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T82 | 280-290 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T83 | 294-298 | Chemical | denotes | haem | http://purl.obolibrary.org/obo/CHEBI_30413 |
T84 | 339-349 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T85 | 382-386 | Chemical | denotes | haem | http://purl.obolibrary.org/obo/CHEBI_30413 |
T86 | 477-479 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T87 | 538-549 | Chemical | denotes | ferric iron | http://purl.obolibrary.org/obo/CHEBI_29034 |
T88 | 545-549 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T89 | 566-574 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T90 | 614-625 | Chemical | denotes | ferric iron | http://purl.obolibrary.org/obo/CHEBI_29034 |
T91 | 621-625 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T92 | 709-717 | Chemical | denotes | hydroxyl | http://purl.obolibrary.org/obo/CHEBI_29191|http://purl.obolibrary.org/obo/CHEBI_43176 |
T94 | 718-726 | Chemical | denotes | radicals | http://purl.obolibrary.org/obo/CHEBI_26519 |
T95 | 755-759 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T96 | 784-786 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T97 | 875-879 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T98 | 986-988 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T99 | 1002-1011 | Chemical | denotes | biomarker | http://purl.obolibrary.org/obo/CHEBI_59163 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6 | 40-69 | http://purl.obolibrary.org/obo/GO_0051651 | denotes | intracellular and sequestered |
T7 | 107-118 | http://purl.obolibrary.org/obo/GO_0045158 | denotes | cytochromes |
T8 | 107-118 | http://purl.obolibrary.org/obo/GO_0045157 | denotes | cytochromes |
T9 | 107-118 | http://purl.obolibrary.org/obo/GO_0045156 | denotes | cytochromes |
T10 | 107-118 | http://purl.obolibrary.org/obo/GO_0008121 | denotes | cytochromes |
T11 | 678-687 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
T12 | 862-874 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | sequestering |
T13 | 964-970 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
T14 | 975-984 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
T15 | 975-984 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T49 | 0-193 | Sentence | denotes | In healthy individuals, iron is largely intracellular and sequestered within ferritin or as a co-factor of cytochromes and FeS proteins, and as haem complexed to hemoglobin within erythrocytes. |
T50 | 194-252 | Sentence | denotes | Circulating iron is rapidly bound by transferrin (28, 29). |
T51 | 253-405 | Sentence | denotes | When erythrocytes lyse and hemoglobin or haem is released into the circulation, their hemoglobin is captured by haptoglobin, and haem by hemopexin (30). |
T52 | 406-592 | Sentence | denotes | Here, circulating serum ferroxidase ceruloplasmin is of importance, as LF can bind to ceruloplasmin, such that a direct transfer of ferric iron between the two proteins is possible (31). |
T53 | 593-783 | Sentence | denotes | A direct transfer of ferric iron from ceruloplasmin to lactoferrin prevents both the formation of potentially toxic hydroxyl radicals (32) and the utilization of iron by pathogenic bacteria. |
T54 | 784-985 | Sentence | denotes | LF is therefore an important player in preventing bacteria from acquiring and sequestering iron, which [with the possible exception of Borrelia burgdorferi (33)]; they require for growth and virulence. |
T55 | 986-1100 | Sentence | denotes | LF also acts as biomarker, as it is commonly upregulated when the host is suffering from various kinds of disease. |
T56 | 1101-1137 | Sentence | denotes | See Table 1 for selected references. |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-19133145-34514583 | 244-246 | 19133145 | denotes | 28 |
32574271-24549403-34514584 | 248-250 | 24549403 | denotes | 29 |
32574271-20711357-34514585 | 401-403 | 20711357 | denotes | 30 |
32574271-22040722-34514586 | 588-590 | 22040722 | denotes | 31 |
32574271-29575574-34514587 | 728-730 | 29575574 | denotes | 32 |
32574271-10834845-34514588 | 941-943 | 10834845 | denotes | 33 |
TEST0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-50-56-2882175 | 244-246 | ["19133145"] | denotes | 28 |
32574271-54-60-2882176 | 248-250 | ["24549403"] | denotes | 29 |
32574271-148-154-2882177 | 401-403 | ["20711357"] | denotes | 30 |
32574271-182-188-2882178 | 588-590 | ["22040722"] | denotes | 31 |
32574271-135-141-2882179 | 728-730 | ["29575574"] | denotes | 32 |
32574271-157-163-2882180 | 941-943 | ["10834845"] | denotes | 33 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-19133145-34514583 | 244-246 | 19133145 | denotes | 28 |
32574271-24549403-34514584 | 248-250 | 24549403 | denotes | 29 |
32574271-20711357-34514585 | 401-403 | 20711357 | denotes | 30 |
32574271-22040722-34514586 | 588-590 | 22040722 | denotes | 31 |
32574271-29575574-34514587 | 728-730 | 29575574 | denotes | 32 |
32574271-10834845-34514588 | 941-943 | 10834845 | denotes | 33 |