PMC:7271924 / 30342-30989 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T549	69-74	NCBITaxon:10239	denotes	virus
T550	94-99	NCBITaxon:10239	denotes	virus
T551	107-119	GO:0009986	denotes	cell surface
T552	151-156	NCBITaxon:10239	denotes	virus
T553	179-183	G_3;PG_10;PR:000003622	denotes	ACE2
T554	270-281	GO:0006260	denotes	replication
T555	349-360	PR:000009978	denotes	Lactoferrin
T556	424-428	G_3;PG_10;PR:000003622	denotes	ACE2
T557	452-463	PR:000009978	denotes	lactoferrin
T558	469-480	PR:000009978	denotes	Lactoferrin
T559	504-508	PR:000014459;SP_7	denotes	SARS
T560	508-514	SP_7	denotes	-CoV-2
T561	574-584	SP_7	denotes	SARS-CoV-2
T562	628-646	GO:0033644	denotes	host cell membrane
T11160	69-74	NCBITaxon:10239	denotes	virus
T78505	94-99	NCBITaxon:10239	denotes	virus
T90756	107-119	GO:0009986	denotes	cell surface
T54560	151-156	NCBITaxon:10239	denotes	virus
T72876	179-183	G_3;PG_10;PR:000003622	denotes	ACE2
T96834	270-281	GO:0006260	denotes	replication
T36697	349-360	PR:000009978	denotes	Lactoferrin
T86359	424-428	G_3;PG_10;PR:000003622	denotes	ACE2
T42997	452-463	PR:000009978	denotes	lactoferrin
T49171	469-480	PR:000009978	denotes	Lactoferrin
T95006	504-508	PR:000014459;SP_7	denotes	SARS
T3005	508-514	SP_7	denotes	-CoV-2
T14660	574-584	SP_7	denotes	SARS-CoV-2
T97248	628-646	GO:0033644	denotes	host cell membrane

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
780	179-183	Gene	denotes	ACE2	Gene:59272
781	349-360	Gene	denotes	Lactoferrin	Gene:280846
782	424-428	Gene	denotes	ACE2	Gene:59272
783	452-463	Gene	denotes	lactoferrin	Gene:280846
784	469-480	Gene	denotes	Lactoferrin	Gene:280846
785	638-646	Gene	denotes	membrane	Gene:43740571
788	504-514	Species	denotes	SARS-CoV-2	Tax:2697049
789	574-584	Species	denotes	SARS-CoV-2	Tax:2697049

Id	Subject	Object	Predicate	Lexical cue	fma_id
T345	56-60	Body_part	denotes	cell	http://purl.org/sig/ont/fma/fma68646
T346	107-119	Body_part	denotes	cell surface	http://purl.org/sig/ont/fma/fma67653
T347	107-111	Body_part	denotes	cell	http://purl.org/sig/ont/fma/fma68646
T348	239-247	Body_part	denotes	clathrin	http://purl.org/sig/ont/fma/fma62262
T349	309-313	Body_part	denotes	cell	http://purl.org/sig/ont/fma/fma68646
T350	385-390	Body_part	denotes	HSPGs	http://purl.org/sig/ont/fma/fma82834
T351	529-533	Body_part	denotes	cell	http://purl.org/sig/ont/fma/fma68646
T352	633-646	Body_part	denotes	cell membrane	http://purl.org/sig/ont/fma/fma63841
T353	633-637	Body_part	denotes	cell	http://purl.org/sig/ont/fma/fma68646

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T117	504-512	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T118	574-582	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091

Id	Subject	Object	Predicate	Lexical cue
T407	56-60	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T408	69-74	http://purl.obolibrary.org/obo/NCBITaxon_10239	denotes	virus
T409	94-99	http://purl.obolibrary.org/obo/NCBITaxon_10239	denotes	virus
T410	107-111	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T411	151-156	http://purl.obolibrary.org/obo/NCBITaxon_10239	denotes	virus
T412	264-269	http://purl.obolibrary.org/obo/NCBITaxon_10239	denotes	Virus
T413	309-313	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T414	385-390	http://purl.obolibrary.org/obo/PR_000001307	denotes	HSPGs
T415	437-438	http://purl.obolibrary.org/obo/CLO_0001020	denotes	a
T416	529-533	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T417	633-637	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T418	638-646	http://purl.obolibrary.org/obo/UBERON_0000158	denotes	membrane

Id	Subject	Object	Predicate	Lexical cue
T237	0-647	Sentence	denotes	This attachment initiates the first contact between the cell and the virus, concentrating the virus on the cell surface, (4) followed attaching of the virus to the host receptor (ACE2) and association and entering are then facilitated via clathrin-coated pits (5) Virus replication can then happen inside the cell. (6) One of the characteristics of Lactoferrin, is that it attaches to HSPGs. (7) Currently we do not know if ACE2 is also a receptor for lactoferrin. (8) Lactoferrin may block the entry of SARS-CoV-2 into the host cell, by occupying HPSGs, thereby preventing SARS-CoV-2 initial attachment and accumulation on the host cell membrane.