PMC:7271924 / 112-970
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 0-11 | PR:000009978 | denotes | Lactoferrin |
| T5 | 17-25 | CHEBI:33284;CHEBI:33284 | denotes | nutrient |
| T6 | 47-56 | NCBITaxon:40674 | denotes | mammalian |
| T7 | 57-61 | UBERON:0001913 | denotes | milk |
| T8 | 147-152 | UBERON:0001977 | denotes | serum |
| T9 | 154-158 | UBERON:0001970 | denotes | bile |
| T10 | 164-183 | UBERON:0001359 | denotes | cerebrospinal fluid |
| T11 | 361-374 | NCBITaxon:11118 | denotes | coronaviruses |
| T12 | 424-453 | CHEBI:24499;CHEBI:24499 | denotes | Heparan Sulfate Proteoglycans |
| T13 | 484-515 | PG_10;PR:000003622 | denotes | angiotensin-converting enzyme 2 |
| T14 | 517-521 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T15 | 579-591 | SP_7 | denotes | severe acute |
| T16 | 592-603 | SP_7;UBERON:0001004 | denotes | respiratory |
| T17 | 604-626 | SP_7 | denotes | syndrome coronavirus 2 |
| T18 | 628-638 | SP_7 | denotes | SARS-CoV-2 |
| T19 | 674-685 | PR:000009978 | denotes | Lactoferrin |
| T20 | 840-848 | SP_7 | denotes | COVID-19 |
| T19283 | 0-11 | PR:000009978 | denotes | Lactoferrin |
| T29712 | 17-25 | CHEBI:33284;CHEBI:33284 | denotes | nutrient |
| T2524 | 47-56 | NCBITaxon:40674 | denotes | mammalian |
| T26128 | 57-61 | UBERON:0001913 | denotes | milk |
| T37236 | 147-152 | UBERON:0001977 | denotes | serum |
| T50067 | 154-158 | UBERON:0001970 | denotes | bile |
| T79141 | 164-183 | UBERON:0001359 | denotes | cerebrospinal fluid |
| T9404 | 361-374 | NCBITaxon:11118 | denotes | coronaviruses |
| T55373 | 424-453 | CHEBI:24499;CHEBI:24499 | denotes | Heparan Sulfate Proteoglycans |
| T61585 | 484-515 | PG_10;PR:000003622 | denotes | angiotensin-converting enzyme 2 |
| T32426 | 517-521 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T25659 | 579-591 | SP_7 | denotes | severe acute |
| T72387 | 592-603 | SP_7;UBERON:0001004 | denotes | respiratory |
| T40621 | 604-626 | SP_7 | denotes | syndrome coronavirus 2 |
| T13307 | 628-638 | SP_7 | denotes | SARS-CoV-2 |
| T31900 | 674-685 | PR:000009978 | denotes | Lactoferrin |
| T9249 | 840-848 | SP_7 | denotes | COVID-19 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 16 | 0-11 | Gene | denotes | Lactoferrin | Gene:280846 |
| 17 | 484-515 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
| 18 | 517-521 | Gene | denotes | ACE2 | Gene:59272 |
| 19 | 553-564 | Gene | denotes | lactoferrin | Gene:280846 |
| 20 | 674-685 | Gene | denotes | Lactoferrin | Gene:280846 |
| 21 | 47-56 | Species | denotes | mammalian | Tax:9606 |
| 22 | 361-374 | Species | denotes | coronaviruses | Tax:11118 |
| 23 | 579-626 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 24 | 628-638 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 25 | 72-76 | Chemical | denotes | iron | MESH:D007501 |
| 26 | 424-439 | Chemical | denotes | Heparan Sulfate | MESH:D006497 |
| 27 | 840-848 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T2 | 57-61 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T3 | 140-145 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T4 | 147-152 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T5 | 154-158 | Body_part | denotes | bile | http://purl.org/sig/ont/fma/fma62971 |
| T6 | 164-183 | Body_part | denotes | cerebrospinal fluid | http://purl.org/sig/ont/fma/fma20935 |
| T7 | 424-453 | Body_part | denotes | Heparan Sulfate Proteoglycans | http://purl.org/sig/ont/fma/fma82834 |
| T8 | 424-439 | Body_part | denotes | Heparan Sulfate | http://purl.org/sig/ont/fma/fma63023 |
| T9 | 424-431 | Body_part | denotes | Heparan | http://purl.org/sig/ont/fma/fma67110 |
| T10 | 455-460 | Body_part | denotes | HSPGs | http://purl.org/sig/ont/fma/fma82834 |
| T11 | 667-672 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 57-61 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T2 | 147-152 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T3 | 154-158 | Body_part | denotes | bile | http://purl.obolibrary.org/obo/UBERON_0001970 |
| T4 | 164-183 | Body_part | denotes | cerebrospinal fluid | http://purl.obolibrary.org/obo/UBERON_0001359 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 579-626 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 579-612 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T3 | 628-636 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T4 | 840-848 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 15-16 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 100-101 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 140-145 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 188-191 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T7 | 424-453 | http://purl.obolibrary.org/obo/PR_000001307 | denotes | Heparan Sulfate Proteoglycans |
| T8 | 455-460 | http://purl.obolibrary.org/obo/PR_000001307 | denotes | HSPGs |
| T9 | 542-552 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T10 | 667-672 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T3 | 17-25 | Chemical | denotes | nutrient | http://purl.obolibrary.org/obo/CHEBI_33284 |
| T4 | 72-76 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
| T5 | 258-267 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T6 | 432-439 | Chemical | denotes | Sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T7 | 484-495 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T8 | 724-726 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 0-62 | Sentence | denotes | Lactoferrin is a nutrient classically found in mammalian milk. |
| T4 | 63-184 | Sentence | denotes | It binds iron and is transferred via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. |
| T5 | 185-268 | Sentence | denotes | It has important immunological properties, and is both antibacterial and antiviral. |
| T6 | 269-405 | Sentence | denotes | In particular, there is evidence that it can bind to at least some of the receptors used by coronaviruses and thereby block their entry. |
| T7 | 406-673 | Sentence | denotes | Of importance are Heparan Sulfate Proteoglycans (HSPGs) and the host receptor angiotensin-converting enzyme 2 (ACE2), as based on other activities lactoferrin might prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from attaching to the host cells. |
| T8 | 674-858 | Sentence | denotes | Lactoferrin (and more specifically enteric-coated LF because of increased bioavailability) may consequently be of preventive and therapeutic value during the present COVID-19 pandemic. |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 424-439 | GlycoEpitope | denotes | Heparan Sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |