PMC:7267243 / 8827-12112
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
266 | 25-30 | Species | denotes | woman | Tax:9606 |
267 | 306-313 | Species | denotes | patient | Tax:9606 |
268 | 361-368 | Species | denotes | patient | Tax:9606 |
269 | 449-459 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
270 | 464-485 | Species | denotes | human metapneumovirus | Tax:162145 |
271 | 487-491 | Species | denotes | hMPV | Tax:162145 |
272 | 519-526 | Species | denotes | patient | Tax:9606 |
273 | 688-709 | Species | denotes | Aspergillus fumigatus | Tax:746128 |
274 | 653-668 | Chemical | denotes | tranexamic acid | MESH:D014148 |
275 | 728-741 | Chemical | denotes | galactomannan | MESH:C012990 |
276 | 759-771 | Chemical | denotes | voriconazole | MESH:D065819 |
277 | 95-99 | Disease | denotes | ARDS | MESH:D012128 |
278 | 180-189 | Disease | denotes | emphysema | MESH:D004646 |
279 | 559-567 | Disease | denotes | bleeding | MESH:D006470 |
289 | 826-834 | Species | denotes | patients | Tax:9606 |
290 | 897-904 | Species | denotes | Patient | Tax:9606 |
291 | 1011-1018 | Species | denotes | Patient | Tax:9606 |
292 | 1097-1104 | Species | denotes | Patient | Tax:9606 |
293 | 1223-1230 | Species | denotes | Patient | Tax:9606 |
294 | 1350-1357 | Species | denotes | Patient | Tax:9606 |
295 | 840-848 | Disease | denotes | COVID‐19 | MESH:C000657245 |
296 | 860-892 | Disease | denotes | Invasive Pulmonary Aspergillosis | MESH:D055744 |
297 | 1243-1252 | Disease | denotes | emphysema | MESH:D004646 |
307 | 1627-1631 | Species | denotes | hMPV | Tax:162145 |
308 | 1633-1643 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
309 | 1648-1669 | Species | denotes | Aspergillus fumigatus | Tax:746128 |
310 | 1875-1882 | Species | denotes | patient | Tax:9606 |
311 | 1694-1707 | Chemical | denotes | galactomannan | MESH:C012990 |
312 | 1758-1771 | Chemical | denotes | galactomannan | MESH:C012990 |
313 | 2017-2030 | Chemical | denotes | isavuconazole | MESH:C508735 |
314 | 1551-1555 | Disease | denotes | ARDS | MESH:D012128 |
315 | 1905-1924 | Disease | denotes | acute renal failure | MESH:D058186 |
322 | 2140-2150 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
323 | 2168-2189 | Species | denotes | Aspergillus fumigatus | Tax:746128 |
324 | 2377-2384 | Species | denotes | patient | Tax:9606 |
325 | 2224-2237 | Chemical | denotes | galactomannan | MESH:C012990 |
326 | 2412-2424 | Chemical | denotes | voriconazole | MESH:D065819 |
327 | 2087-2091 | Disease | denotes | ARDS | MESH:D012128 |
335 | 2542-2552 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
336 | 2558-2579 | Species | denotes | Aspergillus fumigatus | Tax:746128 |
337 | 2730-2737 | Species | denotes | patient | Tax:9606 |
338 | 2519-2521 | Chemical | denotes | TA | |
339 | 2766-2778 | Chemical | denotes | voriconazole | MESH:D065819 |
340 | 2502-2506 | Disease | denotes | ARDS | MESH:D012128 |
341 | 2637-2646 | Disease | denotes | emphysema | MESH:D004646 |
350 | 2804-2809 | Species | denotes | woman | Tax:9606 |
351 | 3141-3148 | Species | denotes | patient | Tax:9606 |
352 | 3240-3247 | Species | denotes | patient | Tax:9606 |
353 | 2884-2894 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
354 | 2861-2863 | Chemical | denotes | TA | |
355 | 2902-2915 | Chemical | denotes | galactomannan | MESH:C012990 |
356 | 3177-3188 | Chemical | denotes | caspofungin | MESH:D000077336 |
357 | 2844-2848 | Disease | denotes | ARDS | MESH:D012128 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T13 | 577-596 | Body_part | denotes | right main bronchus | http://purl.org/sig/ont/fma/fma7395 |
T14 | 807-812 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T15 | 1181-1189 | Body_part | denotes | cavities | http://purl.org/sig/ont/fma/fma76576 |
T16 | 1688-1693 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T17 | 1773-1778 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T18 | 1990-1995 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
T19 | 2239-2244 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T20 | 2328-2336 | Body_part | denotes | cavities | http://purl.org/sig/ont/fma/fma76576 |
T21 | 2607-2612 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T22 | 2896-2901 | Body_part | denotes | Serum | http://purl.org/sig/ont/fma/fma63083 |
T23 | 2953-2958 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T24 | 2968-2973 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T7 | 577-596 | Body_part | denotes | right main bronchus | http://purl.obolibrary.org/obo/UBERON_0002177 |
T8 | 583-596 | Body_part | denotes | main bronchus | http://purl.obolibrary.org/obo/UBERON_0002182 |
T9 | 588-596 | Body_part | denotes | bronchus | http://purl.obolibrary.org/obo/UBERON_0002185 |
T10 | 807-812 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T11 | 1688-1693 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
T12 | 1773-1778 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T13 | 1990-1995 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
T14 | 2239-2244 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T15 | 2607-2612 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T16 | 2896-2901 | Body_part | denotes | Serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
T17 | 2953-2958 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
T18 | 2968-2973 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T101 | 95-99 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T102 | 180-189 | Disease | denotes | emphysema | http://purl.obolibrary.org/obo/MONDO_0004849 |
T103 | 449-453 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T104 | 840-848 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T105 | 879-892 | Disease | denotes | Aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
T106 | 1243-1252 | Disease | denotes | emphysema | http://purl.obolibrary.org/obo/MONDO_0004849 |
T107 | 1551-1555 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T108 | 1633-1637 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T109 | 1905-1924 | Disease | denotes | acute renal failure | http://purl.obolibrary.org/obo/MONDO_0002492 |
T110 | 1911-1924 | Disease | denotes | renal failure | http://purl.obolibrary.org/obo/MONDO_0001106 |
T111 | 2087-2091 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T112 | 2128-2130 | Disease | denotes | TA | http://purl.obolibrary.org/obo/MONDO_0017991 |
T113 | 2140-2144 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T114 | 2502-2506 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T115 | 2519-2521 | Disease | denotes | TA | http://purl.obolibrary.org/obo/MONDO_0017991 |
T116 | 2542-2546 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T117 | 2637-2646 | Disease | denotes | emphysema | http://purl.obolibrary.org/obo/MONDO_0004849 |
T118 | 2844-2848 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T119 | 2861-2863 | Disease | denotes | TA | http://purl.obolibrary.org/obo/MONDO_0017991 |
T120 | 2884-2888 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T61 | 11-12 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T62 | 105-106 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T63 | 163-164 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T64 | 302-304 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T65 | 412-420 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T66 | 464-469 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T67 | 588-596 | http://purl.obolibrary.org/obo/UBERON_0002185 | denotes | bronchus |
T68 | 807-812 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T69 | 894-895 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T70 | 1008-1009 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T71 | 1181-1189 | http://purl.obolibrary.org/obo/UBERON_0002553 | denotes | cavities |
T72 | 1498-1499 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T73 | 1561-1562 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T74 | 1607-1613 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T75 | 1738-1744 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T76 | 1773-1778 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T77 | 1871-1873 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T78 | 1871-1873 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T79 | 1990-1995 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
T80 | 1990-1995 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
T81 | 2054-2058 | http://purl.obolibrary.org/obo/CLO_0001599 | denotes | A 54 |
T82 | 2097-2098 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T83 | 2239-2244 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T84 | 2328-2336 | http://purl.obolibrary.org/obo/UBERON_0002553 | denotes | cavities |
T85 | 2450-2451 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T86 | 2522-2528 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T87 | 2607-2612 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T88 | 2790-2794 | http://purl.obolibrary.org/obo/CLO_0001599 | denotes | A 54 |
T89 | 2864-2870 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T90 | 2968-2973 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T91 | 3137-3139 | http://purl.obolibrary.org/obo/CLO_0008933 | denotes | S5 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T77 | 131-133 | Chemical | denotes | Hg | http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195 |
T79 | 653-668 | Chemical | denotes | tranexamic acid | http://purl.obolibrary.org/obo/CHEBI_48669 |
T80 | 664-668 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T81 | 728-741 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
T82 | 759-771 | Chemical | denotes | voriconazole | http://purl.obolibrary.org/obo/CHEBI_10023 |
T83 | 1587-1589 | Chemical | denotes | Hg | http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195 |
T85 | 1694-1707 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
T86 | 1758-1771 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
T87 | 1871-1873 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T88 | 2017-2030 | Chemical | denotes | isavuconazole | http://purl.obolibrary.org/obo/CHEBI_85979 |
T89 | 2124-2126 | Chemical | denotes | Hg | http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195 |
T91 | 2128-2130 | Chemical | denotes | TA | http://purl.obolibrary.org/obo/CHEBI_74824 |
T92 | 2224-2237 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
T93 | 2373-2375 | Chemical | denotes | S3 | http://purl.obolibrary.org/obo/CHEBI_29388 |
T94 | 2412-2424 | Chemical | denotes | voriconazole | http://purl.obolibrary.org/obo/CHEBI_10023 |
T95 | 2519-2521 | Chemical | denotes | TA | http://purl.obolibrary.org/obo/CHEBI_74824 |
T96 | 2726-2728 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
T97 | 2766-2778 | Chemical | denotes | voriconazole | http://purl.obolibrary.org/obo/CHEBI_10023 |
T98 | 2861-2863 | Chemical | denotes | TA | http://purl.obolibrary.org/obo/CHEBI_74824 |
T99 | 2902-2915 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
T100 | 3137-3139 | Chemical | denotes | S5 | http://purl.obolibrary.org/obo/CHEBI_29386 |
T101 | 3177-3188 | Chemical | denotes | caspofungin | http://purl.obolibrary.org/obo/CHEBI_474180 |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T3 | 728-741 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
T4 | 1694-1707 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
T5 | 1758-1771 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
T6 | 2224-2237 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
T7 | 2902-2915 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T105 | 0-10 | Sentence | denotes | 3 RESULTS |
T106 | 11-55 | Sentence | denotes | A 62‐year‐old woman was admitted to our ICU. |
T107 | 56-134 | Sentence | denotes | She was intubated and developed severe ARDS with a Horowitz‐Index of 53 mm Hg. |
T108 | 135-329 | Sentence | denotes | At the contrast‐enhanced CT a combination of emphysema, bilateral ground‐glass opacities with crazy paving and some peripheral nodular consolidations were seen (Video S1, patient #1, Figure 1A). |
T109 | 330-440 | Sentence | denotes | Despite prone positioning, the patient required rescue veno‐venous extracorporeal membrane oxygenation (ECMO). |
T110 | 441-514 | Sentence | denotes | PCR for SARS‐CoV‐2 and human metapneumovirus (hMPV) was positive in BALF. |
T111 | 515-669 | Sentence | denotes | The patient developed severe intrapulmonary bleeding from the right main bronchus, which was stanched by cold lavages and instillation of tranexamic acid. |
T112 | 670-796 | Sentence | denotes | BALF culture grew Aspergillus fumigatus, was positive for galactomannan, and intravenous voriconazole treatment was commenced. |
T113 | 797-893 | Sentence | denotes | FIGURE 1 Chest CT images of patients with COVID‐19 Associated Invasive Pulmonary Aspergillosis. |
T114 | 894-908 | Sentence | denotes | A, Patient #1: |
T115 | 909-1007 | Sentence | denotes | Combined bilateral ground‐glass opacities with crazy paving and peripheral nodular consolidations. |
T116 | 1008-1022 | Sentence | denotes | B, Patient #2: |
T117 | 1023-1093 | Sentence | denotes | Ground‐glass opacities with small nodular infiltrations of up to 1 cm. |
T118 | 1094-1108 | Sentence | denotes | C, Patient #3: |
T119 | 1109-1219 | Sentence | denotes | Bilateral ground‐glass opacities diffuse nodular infiltrates and cystic cavities and partly air crescent sign. |
T120 | 1220-1234 | Sentence | denotes | D, Patient #4: |
T121 | 1235-1346 | Sentence | denotes | Bullous emphysema and ground‐glass opacities, interstitial changes and consolidations with nodular infiltrates. |
T122 | 1347-1361 | Sentence | denotes | E, Patient #5: |
T123 | 1362-1590 | Sentence | denotes | Ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates A 70‐year‐old man was admitted to the ICU because of ARDS with a Horowitz‐Index of 93 mm Hg. |
T124 | 1591-1670 | Sentence | denotes | PCR on BALF was tested positive for hMPV, SARS‐CoV‐2 and Aspergillus fumigatus. |
T125 | 1671-1728 | Sentence | denotes | Two days before, serum galactomannan had turned positive. |
T126 | 1729-1772 | Sentence | denotes | BALF was tested positive for galactomannan. |
T127 | 1773-1897 | Sentence | denotes | Chest CT showed ground‐glass opacities with some small nodular infiltrations of up to 1 cm (Video S2, patient #2 Figure 1B). |
T128 | 1898-2053 | Sentence | denotes | Due to acute renal failure requiring slow low‐efficient daily dialysis (SLEDD) and elevated liver enzymes, intravenous isavuconazole treatment was started. |
T129 | 2054-2127 | Sentence | denotes | A 54‐year‐old man presented with ARDS with a Horowitz‐Index of 128 mm Hg. |
T130 | 2128-2201 | Sentence | denotes | TA revealed SARS‐CoV‐2 PCR positive and Aspergillus fumigatus in culture. |
T131 | 2202-2238 | Sentence | denotes | BALF was positive for galactomannan. |
T132 | 2239-2399 | Sentence | denotes | Chest CT showed bilateral ground‐glass opacities, diffuse nodular infiltrates and cystic cavities and partly air crescent sign (Video S3, patient #3 Figure 1C). |
T133 | 2400-2449 | Sentence | denotes | Intravenous voriconazole treatment was initiated. |
T134 | 2450-2606 | Sentence | denotes | A 73‐year‐old man was transferred to the ICU due to ARDS with PCR on TA tested positive for SARS‐CoV‐2, and Aspergillus fumigatus that also grew in culture. |
T135 | 2607-2753 | Sentence | denotes | Chest CT showed known bullous emphysema with ground‐glass opacities and consolidations with nodular infiltrates (Video S4, patient #4, Figure 1D). |
T136 | 2754-2789 | Sentence | denotes | Intravenous voriconazole was begun. |
T137 | 2790-2895 | Sentence | denotes | A 54‐year‐old woman was transferred to the ICU due to ARDS with PCR on TA tested positive for SARS‐CoV‐2. |
T138 | 2896-2967 | Sentence | denotes | Serum galactomannan returned positive in two consecutive serum samples. |
T139 | 2968-3164 | Sentence | denotes | Chest CT showed bilateral ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates (Video S5, patient #5, Figure 1E). |
T140 | 3165-3201 | Sentence | denotes | Intravenous caspofungin was started. |
T141 | 3202-3230 | Sentence | denotes | No autopsies were performed. |
T142 | 3231-3285 | Sentence | denotes | Detailed patient characteristics are given in Table 1. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T39 | 180-189 | Phenotype | denotes | emphysema | http://purl.obolibrary.org/obo/HP_0002097 |
T40 | 860-892 | Phenotype | denotes | Invasive Pulmonary Aspergillosis | http://purl.obolibrary.org/obo/HP_0020103 |
T41 | 1201-1218 | Phenotype | denotes | air crescent sign | http://purl.obolibrary.org/obo/HP_0032172 |
T42 | 1243-1252 | Phenotype | denotes | emphysema | http://purl.obolibrary.org/obo/HP_0002097 |
T43 | 1905-1924 | Phenotype | denotes | acute renal failure | http://purl.obolibrary.org/obo/HP_0001919 |
T44 | 1981-2003 | Phenotype | denotes | elevated liver enzymes | http://purl.obolibrary.org/obo/HP_0002910 |
T45 | 2348-2365 | Phenotype | denotes | air crescent sign | http://purl.obolibrary.org/obo/HP_0032172 |
T46 | 2637-2646 | Phenotype | denotes | emphysema | http://purl.obolibrary.org/obo/HP_0002097 |