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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 0-8 Disease denotes COVID‐19 MESH:C000657245
3 20-43 Disease denotes pulmonary aspergillosis MESH:D055732
12 88-96 Species denotes Patients Tax:9606
13 102-137 Disease denotes acute respiratory distress syndrome MESH:D012128
14 139-143 Disease denotes ARDS MESH:D012128
15 152-167 Disease denotes viral infection MESH:D001102
16 213-235 Disease denotes invasive aspergillosis MESH:D055744
17 257-279 Disease denotes coronavirus disease 19 MESH:C000657245
18 281-289 Disease denotes COVID‐19 MESH:C000657245
19 302-324 Disease denotes invasive aspergillosis MESH:D055744
23 410-418 Species denotes patients Tax:9606
24 424-432 Disease denotes COVID‐19 MESH:C000657245
25 444-448 Disease denotes ARDS MESH:D012128
31 675-683 Species denotes patients Tax:9606
32 571-579 Disease denotes COVID‐19 MESH:C000657245
33 591-623 Disease denotes invasive pulmonary aspergillosis MESH:D055744
34 660-674 Disease denotes critically ill MESH:D016638
35 708-712 Disease denotes ARDS MESH:D012128
41 748-756 Species denotes patients Tax:9606
42 762-766 Disease denotes ARDS MESH:D012128
43 774-782 Disease denotes COVID‐19 MESH:C000657245
44 799-831 Disease denotes invasive pulmonary aspergillosis MESH:D055744
45 900-912 Disease denotes co‐infection MESH:D060085
63 1217-1225 Species denotes patients Tax:9606
64 1685-1693 Species denotes patients Tax:9606
65 1607-1616 Species denotes influenza Tax:11309
66 946-975 Disease denotes 2019 coronavirus disease 2019 MESH:C000657245
67 977-985 Disease denotes COVID‐19 MESH:C000657245
68 1118-1150 Disease denotes invasive pulmonary aspergillosis MESH:D055744
69 1231-1266 Disease denotes acute respiratory distress syndrome MESH:D012128
70 1268-1272 Disease denotes ARDS MESH:D012128
71 1281-1296 Disease denotes viral infection MESH:D001102
72 1339-1361 Disease denotes invasive aspergillosis MESH:D055744
73 1493-1502 Disease denotes paralysis MESH:D010243
74 1513-1528 Disease denotes viral infection MESH:D001102
75 1537-1541 Disease denotes ARDS MESH:D012128
76 1546-1553 Disease denotes hypoxia MESH:D000860
77 1638-1651 Disease denotes aspergillosis MESH:D001228
78 1699-1707 Disease denotes COVID‐19 MESH:C000657245
79 1719-1723 Disease denotes ARDS MESH:D012128
81 1781-1789 Species denotes PATIENTS Tax:9606
85 1847-1855 Species denotes patients Tax:9606
86 1861-1869 Disease denotes COVID‐19 MESH:C000657245
87 1874-1878 Disease denotes ARDS MESH:D012128
133 2303-2306 Gene denotes Lap Gene:7939
134 4492-4500 Gene denotes ORF1 a/b Gene:43740578
135 4561-4569 Gene denotes ORF1 a/b Gene:43740578
136 4630-4638 Gene denotes ORF1 a/b Gene:43740578
137 2158-2165 Species denotes Patient Tax:9606
138 2170-2177 Species denotes Patient Tax:9606
139 2182-2189 Species denotes Patient Tax:9606
140 2194-2201 Species denotes Patient Tax:9606
141 2206-2213 Species denotes Patient Tax:9606
142 3379-3400 Species denotes Aspergillus fumigatus Tax:746128
143 3422-3443 Species denotes Aspergillus fumigatus Tax:746128
144 3449-3470 Species denotes Aspergillus fumigatus Tax:746128
145 3737-3758 Species denotes Aspergillus fumigatus Tax:746128
146 3766-3787 Species denotes Aspergillus fumigatus Tax:746128
147 3795-3816 Species denotes Aspergillus fumigatus Tax:746128
148 3822-3843 Species denotes Aspergillus fumigatus Tax:746128
149 4376-4380 Species denotes hMPV Tax:162145
150 4385-4395 Species denotes SARS‐CoV‐2 Tax:2697049
151 4453-4457 Species denotes hMPV Tax:162145
152 4462-4472 Species denotes SARS‐CoV‐2 Tax:2697049
153 4530-4540 Species denotes SARS‐CoV‐2 Tax:2697049
154 4599-4609 Species denotes SARS‐CoV‐2 Tax:2697049
155 4668-4678 Species denotes SARS‐CoV‐2 Tax:2697049
156 3274-3276 Chemical denotes GM MESH:D005839
157 5709-5727 Chemical denotes Hydroxychloroquine MESH:D006886
158 5729-5738 Chemical denotes darunavir MESH:D000069454
159 5743-5753 Chemical denotes cobicistat MESH:D000069547
160 5830-5839 Chemical denotes Ribavirin MESH:D012254
161 5841-5860 Chemical denotes lopinavir/ritonavir MESH:C558899
162 2328-2371 Disease denotes cholecystitis Arterial hypertension Obesity
163 2377-2388 Disease denotes sleep apnea MESH:D012891
164 2400-2430 Disease denotes Hypercholesterolemia Ex‐smoker
165 2464-2468 Disease denotes COPD MESH:D029424
166 2582-2629 Disease denotes hypertension Diabetes mellitus Aneurysm coiling
167 2639-2710 Disease denotes vertebralis Arterial hypertension Bullous Emphysema Smoker Severe COPD MESH:D029424
168 2729-2740 Disease denotes Hepatitis B MESH:D006509
169 2814-2818 Disease denotes COPD MESH:D029424
170 2917-2921 Disease denotes COPD MESH:D029424
171 2937-2970 Disease denotes MICU MICU SICU SICU MICU ARDS MESH:D012128
172 3172-3191 Disease denotes Acute renal failure MESH:D058186
173 3231-3250 Disease denotes SLEDD SLEDD SLEDD
174 5092-5101 Disease denotes emphysema MESH:D004646
175 5928-5932 Disease denotes Died MESH:D003643
176 5934-5938 Disease denotes Died MESH:D003643
177 5947-5951 Disease denotes Died MESH:D003643
182 2047-2054 Species denotes Patient Tax:9606
183 2074-2082 Species denotes patients Tax:9606
184 2088-2096 Disease denotes COVID‐19 MESH:C000657245
185 2108-2140 Disease denotes invasive pulmonary aspergillosis MESH:D055744
196 6372-6375 Gene denotes lap Gene:7939
197 6290-6294 Species denotes hMPV Tax:162145
198 6296-6317 Species denotes human metapneumovirus Tax:162145
199 5974-5978 Disease denotes ARDS MESH:D012128
200 5980-6015 Disease denotes acute respiratory distress syndrome MESH:D012128
201 6070-6074 Disease denotes COPD MESH:D029424
202 6076-6113 Disease denotes chronic obstructive pulmonary disease MESH:D029424
203 6200-6206 Disease denotes Cancer MESH:D009369
204 6256-6288 Disease denotes chronic obstructive lung disease MESH:D029424
205 6324-6356 Disease denotes invasive pulmonary aspergillosis MESH:D055744
207 6872-6880 Disease denotes COVID-19 MESH:C000657245
224 7102-7109 Species denotes patient Tax:9606
225 7113-7123 Species denotes SARS‐CoV‐2 Tax:2697049
226 7164-7172 Species denotes patients Tax:9606
227 7194-7204 Species denotes SARS‐CoV‐2 Tax:2697049
228 7233-7240 Species denotes patient Tax:9606
229 7339-7343 Species denotes hMPV Tax:162145
230 8141-8148 Species denotes patient Tax:9606
231 7412-7423 Species denotes Aspergillus Tax:746128
232 7552-7563 Species denotes Aspergillus Tax:746128
233 7700-7711 Species denotes Aspergillus Tax:746128
234 7595-7608 Chemical denotes galactomannan MESH:C012990
235 7846-7850 Chemical denotes RPMI
236 7851-7855 Chemical denotes agar MESH:D000362
237 7983-7995 Chemical denotes itraconazole MESH:D017964
238 8000-8012 Chemical denotes voriconazole MESH:D065819
239 8175-8180 Chemical denotes azole MESH:D001393
246 8467-8476 Species denotes SARS‐CoV2 Tax:2697049
247 8317-8330 Chemical denotes galactomannan MESH:C012990
248 8195-8203 Disease denotes COVID‐19 MESH:C000657245
249 8477-8486 Disease denotes infection MESH:D007239
250 8492-8496 Disease denotes ARDS MESH:D012128
251 8538-8554 Disease denotes immunodeficiency MESH:D007153
266 8852-8857 Species denotes woman Tax:9606
267 9133-9140 Species denotes patient Tax:9606
268 9188-9195 Species denotes patient Tax:9606
269 9276-9286 Species denotes SARS‐CoV‐2 Tax:2697049
270 9291-9312 Species denotes human metapneumovirus Tax:162145
271 9314-9318 Species denotes hMPV Tax:162145
272 9346-9353 Species denotes patient Tax:9606
273 9515-9536 Species denotes Aspergillus fumigatus Tax:746128
274 9480-9495 Chemical denotes tranexamic acid MESH:D014148
275 9555-9568 Chemical denotes galactomannan MESH:C012990
276 9586-9598 Chemical denotes voriconazole MESH:D065819
277 8922-8926 Disease denotes ARDS MESH:D012128
278 9007-9016 Disease denotes emphysema MESH:D004646
279 9386-9394 Disease denotes bleeding MESH:D006470
289 9653-9661 Species denotes patients Tax:9606
290 9724-9731 Species denotes Patient Tax:9606
291 9838-9845 Species denotes Patient Tax:9606
292 9924-9931 Species denotes Patient Tax:9606
293 10050-10057 Species denotes Patient Tax:9606
294 10177-10184 Species denotes Patient Tax:9606
295 9667-9675 Disease denotes COVID‐19 MESH:C000657245
296 9687-9719 Disease denotes Invasive Pulmonary Aspergillosis MESH:D055744
297 10070-10079 Disease denotes emphysema MESH:D004646
307 10454-10458 Species denotes hMPV Tax:162145
308 10460-10470 Species denotes SARS‐CoV‐2 Tax:2697049
309 10475-10496 Species denotes Aspergillus fumigatus Tax:746128
310 10702-10709 Species denotes patient Tax:9606
311 10521-10534 Chemical denotes galactomannan MESH:C012990
312 10585-10598 Chemical denotes galactomannan MESH:C012990
313 10844-10857 Chemical denotes isavuconazole MESH:C508735
314 10378-10382 Disease denotes ARDS MESH:D012128
315 10732-10751 Disease denotes acute renal failure MESH:D058186
322 10967-10977 Species denotes SARS‐CoV‐2 Tax:2697049
323 10995-11016 Species denotes Aspergillus fumigatus Tax:746128
324 11204-11211 Species denotes patient Tax:9606
325 11051-11064 Chemical denotes galactomannan MESH:C012990
326 11239-11251 Chemical denotes voriconazole MESH:D065819
327 10914-10918 Disease denotes ARDS MESH:D012128
335 11369-11379 Species denotes SARS‐CoV‐2 Tax:2697049
336 11385-11406 Species denotes Aspergillus fumigatus Tax:746128
337 11557-11564 Species denotes patient Tax:9606
338 11346-11348 Chemical denotes TA
339 11593-11605 Chemical denotes voriconazole MESH:D065819
340 11329-11333 Disease denotes ARDS MESH:D012128
341 11464-11473 Disease denotes emphysema MESH:D004646
350 11631-11636 Species denotes woman Tax:9606
351 11968-11975 Species denotes patient Tax:9606
352 12067-12074 Species denotes patient Tax:9606
353 11711-11721 Species denotes SARS‐CoV‐2 Tax:2697049
354 11688-11690 Chemical denotes TA
355 11729-11742 Chemical denotes galactomannan MESH:C012990
356 12004-12015 Chemical denotes caspofungin MESH:D000077336
357 11671-11675 Disease denotes ARDS MESH:D012128
367 12128-12136 Species denotes Patients Tax:9606
368 12335-12343 Species denotes patients Tax:9606
369 12191-12200 Species denotes influenza Tax:11309
370 12142-12146 Disease denotes ARDS MESH:D012128
371 12160-12175 Disease denotes viral infection MESH:D001102
372 12215-12237 Disease denotes invasive aspergillosis MESH:D055744
373 12263-12279 Disease denotes immunodeficiency MESH:D007153
374 12326-12334 Disease denotes COVID‐19 MESH:C000657245
375 12368-12372 Disease denotes ARDS MESH:D012128
378 12468-12476 Disease denotes bleeding MESH:D006470
379 12563-12571 Disease denotes COVID‐19 MESH:C000657245
390 12969-12977 Species denotes patients Tax:9606
391 13234-13242 Species denotes patients Tax:9606
392 12998-13009 Species denotes Aspergillus Tax:746128
393 12726-12748 Disease denotes invasive aspergillosis MESH:D055744
394 12818-12824 Disease denotes Cancer MESH:D009369
395 12903-12911 Disease denotes COVID‐19 MESH:C000657245
396 12964-12968 Disease denotes ARDS MESH:D012128
397 13028-13044 Disease denotes invasive disease MESH:D009361
398 13186-13209 Disease denotes invasive fungal disease MESH:D000072742
399 13213-13227 Disease denotes critically ill MESH:D016638
410 13315-13323 Species denotes patients Tax:9606
411 13565-13573 Species denotes patients Tax:9606
412 13353-13364 Species denotes Aspergillus Tax:746128
413 13458-13469 Species denotes Aspergillus Tax:746128
414 13506-13519 Chemical denotes galactomannan MESH:C012990
415 13291-13305 Disease denotes critically ill MESH:D016638
416 13306-13314 Disease denotes COVID‐19 MESH:C000657245
417 13335-13347 Disease denotes co‐infection MESH:D060085
418 13394-13403 Disease denotes mortality MESH:D003643
419 13552-13560 Disease denotes COVID‐19 MESH:C000657245
424 13811-13819 Species denotes patients Tax:9606
425 13697-13705 Disease denotes COVID‐19 MESH:C000657245
426 13780-13788 Disease denotes COVID‐19 MESH:C000657245
427 13806-13810 Disease denotes ARDS MESH:D012128
435 16052-16055 Chemical denotes DAE
436 13993-13999 Disease denotes Stress MESH:D000079225
437 15766-15768 Disease denotes GS MESH:D011125
438 15813-15833 Disease denotes Novartis Pharma GmbH
439 15861-15863 Disease denotes FD MESH:D004402
440 16005-16007 Disease denotes FD MESH:D004402
441 16936-16945 Disease denotes Infection MESH:D007239

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 3268-3273 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T2 4399-4403 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T3 4418-4422 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T4 4475-4479 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T5 4544-4548 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T6 4613-4617 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T7 4976-4984 Body_part denotes cavities http://purl.org/sig/ont/fma/fma76576
T8 6057-6061 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T9 6276-6280 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 6396-6417 Body_part denotes lumbar vertebral body http://purl.org/sig/ont/fma/fma16075
T11 7622-7627 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T12 8404-8409 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T13 9404-9423 Body_part denotes right main bronchus http://purl.org/sig/ont/fma/fma7395
T14 9634-9639 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T15 10008-10016 Body_part denotes cavities http://purl.org/sig/ont/fma/fma76576
T16 10515-10520 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T17 10600-10605 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T18 10817-10822 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T19 11066-11071 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T20 11155-11163 Body_part denotes cavities http://purl.org/sig/ont/fma/fma76576
T21 11434-11439 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T22 11723-11728 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T23 11780-11785 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T24 11795-11800 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T25 13535-13540 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 2479-2488 Body_part denotes Vertebral http://purl.obolibrary.org/obo/UBERON_3010224
T2 3268-3273 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T3 6276-6280 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 6403-6412 Body_part denotes vertebral http://purl.obolibrary.org/obo/UBERON_3010224
T5 7622-7627 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T6 8404-8409 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T7 9404-9423 Body_part denotes right main bronchus http://purl.obolibrary.org/obo/UBERON_0002177
T8 9410-9423 Body_part denotes main bronchus http://purl.obolibrary.org/obo/UBERON_0002182
T9 9415-9423 Body_part denotes bronchus http://purl.obolibrary.org/obo/UBERON_0002185
T10 9634-9639 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T11 10515-10520 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T12 10600-10605 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T13 10817-10822 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T14 11066-11071 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T15 11434-11439 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T16 11723-11728 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T17 11780-11785 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T18 11795-11800 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T19 13535-13540 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 0-8 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 30-43 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T3 102-137 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T4 108-137 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T5 139-143 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T6 152-167 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T7 158-167 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 213-235 Disease denotes invasive aspergillosis http://purl.obolibrary.org/obo/MONDO_0000240
T9 222-235 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T10 281-289 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 302-324 Disease denotes invasive aspergillosis http://purl.obolibrary.org/obo/MONDO_0000240
T12 311-324 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T13 424-432 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 444-448 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T15 571-579 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 610-623 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T17 708-712 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T18 762-766 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T19 774-782 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 818-831 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T21 903-912 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 951-975 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T23 977-985 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 1137-1150 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T25 1231-1266 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T26 1237-1266 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T27 1268-1272 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T28 1281-1296 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T29 1287-1296 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T30 1339-1361 Disease denotes invasive aspergillosis http://purl.obolibrary.org/obo/MONDO_0000240
T31 1348-1361 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T32 1513-1528 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T33 1519-1528 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T34 1537-1541 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T35 1607-1616 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T36 1638-1651 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T37 1699-1707 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 1719-1723 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T39 1861-1869 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 1874-1878 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T41 2088-2096 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 2127-2140 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T43 2328-2341 Disease denotes cholecystitis http://purl.obolibrary.org/obo/MONDO_0002155
T44 2351-2363 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T45 2364-2371 Disease denotes Obesity http://purl.obolibrary.org/obo/MONDO_0011122
T46 2377-2388 Disease denotes sleep apnea http://purl.obolibrary.org/obo/MONDO_0005296
T47 2464-2468 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T48 2582-2594 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T49 2595-2612 Disease denotes Diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T50 2661-2673 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T51 2682-2691 Disease denotes Emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T52 2706-2710 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T53 2729-2740 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T54 2729-2738 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T55 2814-2818 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T56 2917-2921 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T57 2966-2970 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T58 3172-3191 Disease denotes Acute renal failure http://purl.obolibrary.org/obo/MONDO_0002492
T59 3178-3191 Disease denotes renal failure http://purl.obolibrary.org/obo/MONDO_0001106
T60 3418-3420 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T61 3445-3447 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T62 3472-3474 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T63 3818-3820 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T64 3845-3847 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T65 3858-3860 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T66 4359-4361 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T67 4385-4389 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T68 4436-4438 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T69 4462-4466 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T70 4514-4516 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T71 4530-4534 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T72 4583-4585 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T73 4599-4603 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T74 4652-4654 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T75 4668-4672 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T76 5092-5101 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T77 5974-5978 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T78 5980-6015 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T79 5986-6015 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T80 6070-6113 Disease denotes COPD, chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T81 6096-6113 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T82 6200-6206 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T83 6207-6214 Disease denotes Mycoses http://purl.obolibrary.org/obo/MONDO_0002041
T84 6256-6288 Disease denotes chronic obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0005002
T85 6264-6288 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T86 6276-6288 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T87 6343-6356 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T88 6634-6636 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T89 6872-6880 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T90 7113-7117 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T91 7194-7198 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T92 7687-7689 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T93 8120-8122 Disease denotes BV http://purl.obolibrary.org/obo/MONDO_0005316
T94 8195-8203 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 8349-8351 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T96 8467-8471 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T97 8477-8486 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T98 8492-8496 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T99 8529-8554 Disease denotes acquired immunodeficiency http://purl.obolibrary.org/obo/MONDO_0017769
T100 8538-8554 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T101 8922-8926 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T102 9007-9016 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T103 9276-9280 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T104 9667-9675 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 9706-9719 Disease denotes Aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T106 10070-10079 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T107 10378-10382 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T108 10460-10464 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T109 10732-10751 Disease denotes acute renal failure http://purl.obolibrary.org/obo/MONDO_0002492
T110 10738-10751 Disease denotes renal failure http://purl.obolibrary.org/obo/MONDO_0001106
T111 10914-10918 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T112 10955-10957 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T113 10967-10971 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T114 11329-11333 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T115 11346-11348 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T116 11369-11373 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T117 11464-11473 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T118 11671-11675 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T119 11688-11690 Disease denotes TA http://purl.obolibrary.org/obo/MONDO_0017991
T120 11711-11715 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T121 12142-12146 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T122 12160-12175 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T123 12166-12175 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T124 12191-12200 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T125 12215-12237 Disease denotes invasive aspergillosis http://purl.obolibrary.org/obo/MONDO_0000240
T126 12224-12237 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T127 12263-12287 Disease denotes immunodeficiency. 2 , 3 http://purl.obolibrary.org/obo/MONDO_0014353
T128 12263-12282 Disease denotes immunodeficiency. 2 http://purl.obolibrary.org/obo/MONDO_0010518
T129 12263-12279 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T130 12326-12334 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T131 12368-12372 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T132 12563-12571 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 12726-12748 Disease denotes invasive aspergillosis http://purl.obolibrary.org/obo/MONDO_0000240
T134 12735-12748 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T135 12818-12824 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T136 12825-12832 Disease denotes Mycoses http://purl.obolibrary.org/obo/MONDO_0002041
T137 12903-12911 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T138 12964-12968 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T139 13306-13314 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 13338-13347 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 13552-13560 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T142 13697-13705 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T143 13780-13788 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 13806-13810 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T145 14214-14217 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T146 14883-14886 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T147 15187-15190 Disease denotes ALS http://purl.obolibrary.org/obo/MONDO_0004976
T148 15766-15768 Disease denotes GS http://purl.obolibrary.org/obo/MONDO_0005773
T149 16803-16806 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T150 16936-16945 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T151 16995-16998 Disease denotes CRC http://purl.obolibrary.org/obo/MONDO_0005575|http://purl.obolibrary.org/obo/MONDO_0024331
T153 17008-17011 Disease denotes CRC http://purl.obolibrary.org/obo/MONDO_0005575|http://purl.obolibrary.org/obo/MONDO_0024331
T155 17159-17162 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T156 17352-17355 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T157 17443-17446 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088
T158 17551-17554 Disease denotes MSD http://purl.obolibrary.org/obo/MONDO_0010088

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 77-87 http://purl.obolibrary.org/obo/BFO_0000030 denotes Objectives
T2 328-329 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 374-375 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T4 1079-1080 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1435-1441 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3 , 4
T6 1760-1761 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1815-1816 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1959-1960 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 2013-2015 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T10 2225-2231 http://purl.obolibrary.org/obo/UBERON_0003100 denotes Female
T11 2233-2237 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T12 2233-2237 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T13 2239-2243 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T14 2239-2243 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T15 2245-2249 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T16 2245-2249 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T17 2251-2257 http://purl.obolibrary.org/obo/UBERON_0003100 denotes Female
T18 2342-2350 http://purl.obolibrary.org/obo/UBERON_0001637 denotes Arterial
T19 2342-2350 http://www.ebi.ac.uk/efo/EFO_0000814 denotes Arterial
T20 2479-2488 http://purl.obolibrary.org/obo/NCBITaxon_7742 denotes Vertebral
T21 2508-2512 http://purl.obolibrary.org/obo/CLO_0007190 denotes L4/5
T22 2573-2581 http://purl.obolibrary.org/obo/UBERON_0001637 denotes Arterial
T23 2573-2581 http://www.ebi.ac.uk/efo/EFO_0000814 denotes Arterial
T24 2636-2637 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T25 2652-2660 http://purl.obolibrary.org/obo/UBERON_0001637 denotes Arterial
T26 2652-2660 http://www.ebi.ac.uk/efo/EFO_0000814 denotes Arterial
T27 2739-2740 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T28 3500-3507 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T29 3527-3528 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 4399-4403 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T31 4418-4422 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T32 4475-4479 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T33 4497-4498 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 4499-4500 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T35 4544-4548 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T36 4566-4567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T37 4568-4569 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T38 4613-4617 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T39 4635-4636 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 4637-4638 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T41 4831-4833 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T42 4901-4903 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T43 4901-4903 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T44 4976-4984 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavities
T45 5268-5270 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T46 6157-6169 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T47 6276-6280 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T48 6276-6280 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T49 6296-6301 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T50 6403-6412 http://purl.obolibrary.org/obo/NCBITaxon_7742 denotes vertebral
T51 6692-6700 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T52 6714-6715 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 6743-6750 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T54 7205-7209 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T55 7476-7480 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T56 7609-7616 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T57 7785-7796 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing was
T58 7967-7971 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T59 8063-8065 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T60 8089-8091 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T61 8838-8839 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T62 8932-8933 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 8990-8991 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 9129-9131 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T65 9239-9247 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T66 9291-9296 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T67 9415-9423 http://purl.obolibrary.org/obo/UBERON_0002185 denotes bronchus
T68 9634-9639 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T69 9721-9722 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T70 9835-9836 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T71 10008-10016 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavities
T72 10325-10326 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T73 10388-10389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74 10434-10440 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T75 10565-10571 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T76 10600-10605 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T77 10698-10700 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T78 10698-10700 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T79 10817-10822 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T80 10817-10822 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T81 10881-10885 http://purl.obolibrary.org/obo/CLO_0001599 denotes A 54
T82 10924-10925 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83 11066-11071 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T84 11155-11163 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavities
T85 11277-11278 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T86 11349-11355 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T87 11434-11439 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T88 11617-11621 http://purl.obolibrary.org/obo/CLO_0001599 denotes A 54
T89 11691-11697 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T90 11795-11800 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T91 11964-11966 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T92 12775-12787 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T93 12936-12937 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 13120-13121 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 13430-13437 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T96 13596-13598 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T97 13728-13731 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T98 13846-13849 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T99 14528-14531 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T100 14702-14704 http://www.ebi.ac.uk/efo/EFO_0000265 denotes Da
T101 16056-16059 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T102 16243-16245 http://purl.obolibrary.org/obo/CLO_0007706 denotes MH
T103 17210-17213 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T104 17252-17255 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T105 17403-17405 http://purl.obolibrary.org/obo/CLO_0001869 denotes BB
T106 17409-17410 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 17815-17816 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T108 18187-18188 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T109 19687-19689 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T110 19733-19735 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T111 19733-19735 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T112 19871-19873 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1152-1155 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T3 2435-2437 Chemical denotes PY http://purl.obolibrary.org/obo/CHEBI_74799
T4 2470-2474 Chemical denotes GOLD http://purl.obolibrary.org/obo/CHEBI_59965
T5 2712-2716 Chemical denotes GOLD http://purl.obolibrary.org/obo/CHEBI_59965
T6 2801-2809 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T7 2838-2852 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T8 2904-2912 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T9 3015-3017 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T11 3034-3036 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T13 3056-3058 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T15 3075-3077 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T17 3097-3099 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T19 3274-3276 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T20 3418-3420 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T21 3445-3447 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T22 3472-3474 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T23 3564-3576 Chemical denotes Itraconazole http://purl.obolibrary.org/obo/CHEBI_6076
T24 3577-3580 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T25 3607-3610 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T26 3643-3655 Chemical denotes Itraconazole http://purl.obolibrary.org/obo/CHEBI_6076
T27 3656-3659 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T28 3686-3689 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T29 3818-3820 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T30 3845-3847 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T31 3858-3860 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T32 3866-3868 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T33 3989-3992 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T35 3999-4002 Chemical denotes MSG http://purl.obolibrary.org/obo/CHEBI_64220|http://purl.obolibrary.org/obo/CHEBI_64243
T37 4272-4274 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T38 4330-4332 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T39 4359-4361 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T40 4436-4438 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T41 4514-4516 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T42 4583-4585 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T43 4652-4654 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T44 4901-4903 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T45 5014-5016 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T46 5109-5111 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T47 5268-5270 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T48 5433-5444 Chemical denotes Caspofungin http://purl.obolibrary.org/obo/CHEBI_474180
T49 5479-5491 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T50 5567-5578 Chemical denotes Caspofungin http://purl.obolibrary.org/obo/CHEBI_474180
T51 5613-5625 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T52 5729-5738 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T53 5743-5753 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T54 5841-5860 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T55 5841-5850 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T56 5851-5860 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T57 6143-6146 Chemical denotes MSG http://purl.obolibrary.org/obo/CHEBI_64220|http://purl.obolibrary.org/obo/CHEBI_64243
T59 6228-6232 Chemical denotes GOLD http://purl.obolibrary.org/obo/CHEBI_59965
T60 6319-6322 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T62 6434-6437 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T63 6549-6551 Chemical denotes PY http://purl.obolibrary.org/obo/CHEBI_74799
T64 6634-6636 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T65 7595-7608 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T66 7687-7689 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T67 7712-7719 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T68 7851-7855 Chemical denotes agar http://purl.obolibrary.org/obo/CHEBI_2509
T69 7963-7966 Chemical denotes MIC http://purl.obolibrary.org/obo/CHEBI_59059
T70 7983-7995 Chemical denotes itraconazole http://purl.obolibrary.org/obo/CHEBI_6076
T71 8000-8012 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T72 8175-8180 Chemical denotes azole http://purl.obolibrary.org/obo/CHEBI_68452
T73 8215-8218 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T75 8317-8330 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T76 8349-8351 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T77 8958-8960 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T79 9480-9495 Chemical denotes tranexamic acid http://purl.obolibrary.org/obo/CHEBI_48669
T80 9491-9495 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T81 9555-9568 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T82 9586-9598 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T83 10414-10416 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T85 10521-10534 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T86 10585-10598 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T87 10698-10700 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T88 10844-10857 Chemical denotes isavuconazole http://purl.obolibrary.org/obo/CHEBI_85979
T89 10951-10953 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T91 10955-10957 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T92 11051-11064 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T93 11200-11202 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T94 11239-11251 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T95 11346-11348 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T96 11553-11555 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T97 11593-11605 Chemical denotes voriconazole http://purl.obolibrary.org/obo/CHEBI_10023
T98 11688-11690 Chemical denotes TA http://purl.obolibrary.org/obo/CHEBI_74824
T99 11729-11742 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T100 11964-11966 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T101 12004-12015 Chemical denotes caspofungin http://purl.obolibrary.org/obo/CHEBI_474180
T102 12308-12311 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T104 12522-12525 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T106 12583-12586 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T108 12654-12657 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T110 13506-13519 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680
T111 13687-13690 Chemical denotes IPA http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802
T113 13800-13802 Chemical denotes IA http://purl.obolibrary.org/obo/CHEBI_74062
T114 13843-13845 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T115 15459-15461 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T116 15766-15768 Chemical denotes GS http://purl.obolibrary.org/obo/CHEBI_73516
T117 15861-15863 Chemical denotes FD http://purl.obolibrary.org/obo/CHEBI_73631
T118 15949-15951 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T120 16005-16007 Chemical denotes FD http://purl.obolibrary.org/obo/CHEBI_73631
T121 16031-16034 Chemical denotes BMC http://purl.obolibrary.org/obo/CHEBI_3392
T122 16095-16097 Chemical denotes FF http://purl.obolibrary.org/obo/CHEBI_72723
T123 16243-16245 Chemical denotes MH http://purl.obolibrary.org/obo/CHEBI_74703
T124 16895-16897 Chemical denotes FK http://purl.obolibrary.org/obo/CHEBI_141443
T125 17109-17111 Chemical denotes FK http://purl.obolibrary.org/obo/CHEBI_141443
T126 17207-17209 Chemical denotes TP http://purl.obolibrary.org/obo/CHEBI_73662
T127 17277-17279 Chemical denotes MK http://purl.obolibrary.org/obo/CHEBI_74706
T128 17403-17405 Chemical denotes BB http://purl.obolibrary.org/obo/CHEBI_53109
T129 19733-19735 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T130 19779-19781 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T131 19825-19827 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T132 19871-19873 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 152-167 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T2 1281-1296 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T3 1513-1528 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T4 2377-2382 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T5 12160-12175 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T6 13491-13501 http://purl.obolibrary.org/obo/GO_0046903 denotes secretions
T7 14013-14018 http://purl.obolibrary.org/obo/GO_0007568 denotes Aging

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 7595-7608 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T2 8317-8330 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T3 9555-9568 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T4 10521-10534 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T5 10585-10598 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T6 11051-11064 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T7 11729-11742 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510
T8 13506-13519 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-43 Sentence denotes COVID‐19 associated pulmonary aspergillosis
T2 44-57 Sentence denotes KOEHLER et al
T3 59-67 Sentence denotes Abstract
T4 68-75 Sentence denotes Summary
T5 77-87 Sentence denotes Objectives
T6 88-236 Sentence denotes Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis.
T7 237-364 Sentence denotes Our study evaluates coronavirus disease 19 (COVID‐19) associated invasive aspergillosis at a single centre in Cologne, Germany.
T8 366-373 Sentence denotes Methods
T9 374-561 Sentence denotes A retrospective chart review of all patients with COVID‐19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany.
T10 563-570 Sentence denotes Results
T11 571-713 Sentence denotes COVID‐19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS.
T12 715-725 Sentence denotes Conclusion
T13 726-913 Sentence denotes Clinicians caring for patients with ARDS due to COVID‐19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co‐infection.
T14 915-930 Sentence denotes 1 INTRODUCTION
T15 931-1097 Sentence denotes Since December 2019 coronavirus disease 2019 (COVID‐19) emerged from Wuhan City, Hubei province, China and rapidly spread around the globe becoming a pandemic threat.
T16 1098-1207 Sentence denotes 1 Risk factors for invasive pulmonary aspergillosis (IPA) are well defined in immunocompromised populations.
T17 1208-1429 Sentence denotes However, patients with acute respiratory distress syndrome (ARDS) due to viral infection are prone to secondary complications like invasive aspergillosis despite lack of underlying well‐defined immunocompromising disease.
T18 1430-1591 Sentence denotes 2 , 3 , 4 Possible explanations for this could be an immune‐paralysis caused by viral infection‐induced ARDS and hypoxia compromising the innate host defence.
T19 1592-1776 Sentence denotes 5 In light of influenza‐pulmonary associated aspergillosis, we retrospectively analysed our patients with COVID‐19 associated ARDS in the intensive care unit (ICU) at a single centre.
T20 1778-1801 Sentence denotes 2 PATIENTS AND METHODS
T21 1802-2037 Sentence denotes We performed a retrospective chart review of patients with COVID‐19 and ARDS admitted to the medical and surgical ICU at the University Hospital of Cologne, a 1540‐bed teaching hospital between 7 March 2020 and 22 April 2020 (Table 1).
T22 2038-2140 Sentence denotes TABLE 1 Patient characteristics of patients with COVID‐19 associated invasive pulmonary aspergillosis
T23 2141-2216 Sentence denotes Characteristics Patient #1 Patient #2 Patient #3 Patient #4 Patient #5
T24 2217-2257 Sentence denotes Gender Female Male Male Male Female
T25 2258-2285 Sentence denotes Age (y) 62 70 54 73 54
T26 2286-2341 Sentence denotes Medical history Lap. cholecystectomy for cholecystitis
T27 2342-2363 Sentence denotes Arterial hypertension
T28 2364-2399 Sentence denotes Obesity with sleep apnea (BMI 31.5)
T29 2400-2420 Sentence denotes Hypercholesterolemia
T30 2421-2454 Sentence denotes Ex‐smoker (30 PY; 5 y previously)
T31 2455-2539 Sentence denotes Moderate COPD (GOLD 2) Vertebral disc prolapse left L4/5, flavectomy and nucleotomy
T32 2540-2594 Sentence denotes Ex‐smoker (4 months previously) Arterial hypertension
T33 2595-2612 Sentence denotes Diabetes mellitus
T34 2613-2673 Sentence denotes Aneurysm coiling right A. vertebralis Arterial hypertension
T35 2674-2691 Sentence denotes Bullous Emphysema
T36 2692-2698 Sentence denotes Smoker
T37 2699-2719 Sentence denotes Severe COPD (GOLD 3)
T38 2720-2744 Sentence denotes Previous Hepatitis B No
T39 2745-2926 Sentence denotes Underlying immuno‐compromising condition (inhalational steroids for COPD) No (intravenous corticosteroid therapy 0.4 mg/kg/d, total of 13 d) (inhalational steroids for COPD) No
T40 2927-2965 Sentence denotes ICU Ward MICU MICU SICU SICU MICU
T41 2966-2970 Sentence denotes ARDS
T42 2971-3100 Sentence denotes Horowitz‐Index, admission 12 Severe (53 mm Hg) Severe (93 mm Hg) Moderate (128 mm Hg) Severe (83 mm Hg) Moderate (167 mm Hg)
T43 3101-3143 Sentence denotes Prone positioning Yes Yes Yes Yes Yes
T44 3144-3171 Sentence denotes vvECMO Yes No No No No
T45 3172-3216 Sentence denotes Acute renal failure Yes Yes Yes Yes Yes
T46 3217-3254 Sentence denotes Dialysis No SLEDD SLEDD SLEDD No
T47 3255-3267 Sentence denotes Microbiology
T48 3268-3356 Sentence denotes Serum GM (>0.5) Negative Positive (0.7) Negative Negative 2× positive (2.7 and 1.3)
T49 3357-3378 Sentence denotes Fungal culture BALF:
T50 3379-3421 Sentence denotes Aspergillus fumigatus BALF: negative TA:
T51 3422-3448 Sentence denotes Aspergillus fumigatus TA:
T52 3449-3484 Sentence denotes Aspergillus fumigatus TA: negative
T53 3485-3563 Sentence denotes Susceptibility testing Azole susceptible a Not applicable Azole susceptible
T54 3564-3593 Sentence denotes Itraconazole MIC 0.380 (mg/L)
T55 3594-3642 Sentence denotes Voriconazole MIC 0.094 (mg/L) Azole susceptible
T56 3643-3672 Sentence denotes Itraconazole MIC 0.380 (mg/L)
T57 3673-3718 Sentence denotes Voriconazole MIC 0.094 (mg/L) Not applicable
T58 3719-3736 Sentence denotes Fungal PCR BALF:
T59 3737-3765 Sentence denotes Aspergillus fumigatus BALF:
T60 3766-3794 Sentence denotes Aspergillus fumigatus BALF:
T61 3795-3821 Sentence denotes Aspergillus fumigatus TA:
T62 3822-3857 Sentence denotes Aspergillus fumigatus TA: negative
T63 3858-3882 Sentence denotes TA/BALF GM (>0.5) BALF:
T64 3883-3905 Sentence denotes Positive (>2.5) BALF:
T65 3906-3928 Sentence denotes Positive (>2.5) BALF:
T66 3929-3974 Sentence denotes Positive (>2.5) Not available Not available
T67 3975-3992 Sentence denotes Definition of IPA
T68 3993-4203 Sentence denotes EORTC/MSG Criteria 8 Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion) Not classifiable (no host criterion)
T69 4204-4344 Sentence denotes (modified) AspICU algorithm 3 , 7 Putative Modified putative 3 (GM positivity) Putative Putative Modified putative 3 (GM positivity)
T70 4345-4353 Sentence denotes Virology
T71 4354-4404 Sentence denotes PCR TA: positive for hMPV and SARS‐CoV‐2 (E‐gene:
T72 4405-4423 Sentence denotes C t 13.29; S‐gene:
T73 4424-4480 Sentence denotes C t 12.61) TA: positive for hMPV and SARS‐CoV‐2(E‐gene:
T74 4481-4501 Sentence denotes C t 34.29; ORF1 a/b:
T75 4502-4549 Sentence denotes C t 31.47) TA positive for SARS‐CoV‐2 (E‐gene:
T76 4550-4570 Sentence denotes C t 29.74; ORF1 a/b:
T77 4571-4618 Sentence denotes C t 27.86) TA positive for SARS‐CoV‐2 (E‐gene:
T78 4619-4639 Sentence denotes C t 21.47; ORF1 a/b:
T79 4640-4705 Sentence denotes C t 20.12) TA positive for SARS‐CoV‐2 (C t values not available)
T80 4706-5282 Sentence denotes CT imaging studies Combined bilateral ground‐glass opacities with crazy paving and peripheral nodular consolidations (Video S1, Figure 1A) Ground‐glass opacities with occasional nodules (Video S2, Figure 1B) Bilateral ground‐glass opacities, nodular infiltrates with cavities and air crescent sign (Video S3, Figure 1C) Ground‐glass opacities with occasional nodules, known bullous emphysema (Video S4, Figure 1D) Ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates (Video S5, Figure 1E)
T81 5283-5290 Sentence denotes Therapy
T82 5291-5655 Sentence denotes Antifungal treatment Voriconazole iv (6/4 mg/kg BW twice daily) Isavuconazole iv (200 mg thrice daily for 2 d; 200 mg once daily from 3 d) Caspofungin (70/50 mg once daily) followed by voriconazole iv (6/4 mg/kg BW twice daily) Voriconazole iv (6/4 mg/kg BW twice daily) Caspofungin (70/50 mg once daily) followed by voriconazole iv (6/4 mg/kg BW twice daily)
T83 5656-5918 Sentence denotes Antiviral therapy Supportive only Supportive only Hydroxychloroquine, darunavir and cobicistat at external hospital, in house changed to supportive only Supportive only Ribavirin, lopinavir/ritonavir at external hospital, in house changed to supportive only
T84 5919-5958 Sentence denotes Outcome Died Died Alive Died Alive
T85 5959-6713 Sentence denotes Abbreviations: ARDS, acute respiratory distress syndrome; BALF, bronchoalveolar lavage fluid; BW, body weight; COPD, chronic obstructive pulmonary disease; C t, threshold cycle; EORTC/MSG, European Organization for Research and Treatment of Cancer/Mycoses Study Group; GOLD, global initiative for chronic obstructive lung disease; hMPV, human metapneumovirus; IPA, invasive pulmonary aspergillosis; kg, kilogram; lap, laparoscopic; LVB, lumbar vertebral body; mg, milligram; MIC, minimal inhibitory concentration; MICU, medical ICU; ORF, open reading frame; PCR, polymerase chain reaction; PY, pack‐year history; SICU, surgical ICU; SLEDD, slow low‐efficient daily dialysis; TA, tracheal aspirate; vvECMO, veno‐venous extracorporeal membrane oxygenation.
T86 6714-6764 Sentence denotes a Antifungal susceptibility testing by VIPcheck™.
T87 6765-6766 Sentence denotes 6
T88 6767-6914 Sentence denotes John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response.
T89 6915-7097 Sentence denotes It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
T90 7098-7228 Sentence denotes For patient #1 SARS‐CoV‐2 RT‐PCR Kit (altona Diagnostics) and for patients #2, #3 and #4 cobas® SARS‐CoV‐2 Test (Roche) were used.
T91 7229-7278 Sentence denotes For patient #5, kit manufacturer remains unknown.
T92 7279-7411 Sentence denotes Respective C t values are given in Table 1 where available. hMPV‐PCR was performed with NxTAG® Respiratory Pathogen Panel (Luminex).
T93 7412-7504 Sentence denotes Aspergillus 28S rDNA‐Realtime PCR was performed as in‐house PCR test for screening purposes.
T94 7505-7569 Sentence denotes Species identification was performed by artus® Aspergillus diff.
T95 7570-7590 Sentence denotes RG PCR kit (Qiagen).
T96 7591-7758 Sentence denotes For galactomannan testing from serum, bronchoalveolar lavage fluid (BALF) or tracheal aspirate (TA) Platelia Aspergillus antigen ELISA (Bio‐Rad Laboratories) was used.
T97 7759-7863 Sentence denotes Antifungal susceptibility testing was performed using concentration gradient strips on RPMI agar plates.
T98 7864-8026 Sentence denotes In brief, spore suspensions of the fungal isolates were adjusted to 106 CFU/mL and inoculated with MIC test strips for itraconazole and voriconazole (bioMérieux).
T99 8027-8094 Sentence denotes MICs were determined visually after 48 hours of incubation at 35°C.
T100 8095-8192 Sentence denotes VIPcheck™ (Mediaproducts BV) was performed in patient #1 for early detection of azole resistance.
T101 8193-8194 Sentence denotes 6
T102 8195-8456 Sentence denotes COVID‐19 associated IPA was classified according to the (modified) 3 AspICU algorithm 7 with the addition that positive galactomannan (≥1) from BALF or TA, or two consecutively but separately drawn positive serum samples (≥1) were accepted as entry criterion.
T103 8457-8566 Sentence denotes 8 Severe SARS‐CoV2 infection with ARDS was accepted as host criterion (acquired immunodeficiency) (Table 1).
T104 8567-8825 Sentence denotes This study was carried out in accordance with the ethical principles reflected in the Declaration of Helsinki 9 and was approved by the ethic committee of the University Hospital of Cologne (Identifier of the University of Cologne Ethics Committee 20‐1157).
T105 8827-8837 Sentence denotes 3 RESULTS
T106 8838-8882 Sentence denotes A 62‐year‐old woman was admitted to our ICU.
T107 8883-8961 Sentence denotes She was intubated and developed severe ARDS with a Horowitz‐Index of 53 mm Hg.
T108 8962-9156 Sentence denotes At the contrast‐enhanced CT a combination of emphysema, bilateral ground‐glass opacities with crazy paving and some peripheral nodular consolidations were seen (Video S1, patient #1, Figure 1A).
T109 9157-9267 Sentence denotes Despite prone positioning, the patient required rescue veno‐venous extracorporeal membrane oxygenation (ECMO).
T110 9268-9341 Sentence denotes PCR for SARS‐CoV‐2 and human metapneumovirus (hMPV) was positive in BALF.
T111 9342-9496 Sentence denotes The patient developed severe intrapulmonary bleeding from the right main bronchus, which was stanched by cold lavages and instillation of tranexamic acid.
T112 9497-9623 Sentence denotes BALF culture grew Aspergillus fumigatus, was positive for galactomannan, and intravenous voriconazole treatment was commenced.
T113 9624-9720 Sentence denotes FIGURE 1 Chest CT images of patients with COVID‐19 Associated Invasive Pulmonary Aspergillosis.
T114 9721-9735 Sentence denotes A, Patient #1:
T115 9736-9834 Sentence denotes Combined bilateral ground‐glass opacities with crazy paving and peripheral nodular consolidations.
T116 9835-9849 Sentence denotes B, Patient #2:
T117 9850-9920 Sentence denotes Ground‐glass opacities with small nodular infiltrations of up to 1 cm.
T118 9921-9935 Sentence denotes C, Patient #3:
T119 9936-10046 Sentence denotes Bilateral ground‐glass opacities diffuse nodular infiltrates and cystic cavities and partly air crescent sign.
T120 10047-10061 Sentence denotes D, Patient #4:
T121 10062-10173 Sentence denotes Bullous emphysema and ground‐glass opacities, interstitial changes and consolidations with nodular infiltrates.
T122 10174-10188 Sentence denotes E, Patient #5:
T123 10189-10417 Sentence denotes Ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates A 70‐year‐old man was admitted to the ICU because of ARDS with a Horowitz‐Index of 93 mm Hg.
T124 10418-10497 Sentence denotes PCR on BALF was tested positive for hMPV, SARS‐CoV‐2 and Aspergillus fumigatus.
T125 10498-10555 Sentence denotes Two days before, serum galactomannan had turned positive.
T126 10556-10599 Sentence denotes BALF was tested positive for galactomannan.
T127 10600-10724 Sentence denotes Chest CT showed ground‐glass opacities with some small nodular infiltrations of up to 1 cm (Video S2, patient #2 Figure 1B).
T128 10725-10880 Sentence denotes Due to acute renal failure requiring slow low‐efficient daily dialysis (SLEDD) and elevated liver enzymes, intravenous isavuconazole treatment was started.
T129 10881-10954 Sentence denotes A 54‐year‐old man presented with ARDS with a Horowitz‐Index of 128 mm Hg.
T130 10955-11028 Sentence denotes TA revealed SARS‐CoV‐2 PCR positive and Aspergillus fumigatus in culture.
T131 11029-11065 Sentence denotes BALF was positive for galactomannan.
T132 11066-11226 Sentence denotes Chest CT showed bilateral ground‐glass opacities, diffuse nodular infiltrates and cystic cavities and partly air crescent sign (Video S3, patient #3 Figure 1C).
T133 11227-11276 Sentence denotes Intravenous voriconazole treatment was initiated.
T134 11277-11433 Sentence denotes A 73‐year‐old man was transferred to the ICU due to ARDS with PCR on TA tested positive for SARS‐CoV‐2, and Aspergillus fumigatus that also grew in culture.
T135 11434-11580 Sentence denotes Chest CT showed known bullous emphysema with ground‐glass opacities and consolidations with nodular infiltrates (Video S4, patient #4, Figure 1D).
T136 11581-11616 Sentence denotes Intravenous voriconazole was begun.
T137 11617-11722 Sentence denotes A 54‐year‐old woman was transferred to the ICU due to ARDS with PCR on TA tested positive for SARS‐CoV‐2.
T138 11723-11794 Sentence denotes Serum galactomannan returned positive in two consecutive serum samples.
T139 11795-11991 Sentence denotes Chest CT showed bilateral ground‐glass opacities, smaller areas with crazy paving pattern, central and peripheral consolidations, and smaller nodular infiltrates (Video S5, patient #5, Figure 1E).
T140 11992-12028 Sentence denotes Intravenous caspofungin was started.
T141 12029-12057 Sentence denotes No autopsies were performed.
T142 12058-12112 Sentence denotes Detailed patient characteristics are given in Table 1.
T143 12114-12127 Sentence denotes 4 DISCUSSION
T144 12128-12280 Sentence denotes Patients with ARDS triggered by viral infection, in particular influenza, are prone to invasive aspergillosis even in absence of prior immunodeficiency.
T145 12281-12440 Sentence denotes 2 , 3 We report putative IPA in five of 19 COVID‐19 patients with moderate to severe ARDS without underlying immunocompromising disease on two separate ICUs.
T146 12441-12526 Sentence denotes Spontaneous intrapulmonary bleeding and haemoptysis are typical complications of IPA.
T147 12527-12658 Sentence denotes Ground‐glass opacities characterise COVID‐19 as well as IPA, thus comprehensive microbiological evaluation can prevent missing IPA.
T148 12659-12923 Sentence denotes By applying strict interpretation of the host and risk factors for invasive aspergillosis according to the European Organization for Research and Treatment of Cancer/Mycoses Study Group definitions the risk of missed diagnosis increases in the COVID‐19 population.
T149 12924-13096 Sentence denotes 8 However, a most complicated issue in ARDS patients is to differentiate Aspergillus colonisation from invasive disease—especially as radiological imaging is non‐specific.
T150 13097-13243 Sentence denotes To address this issue, a consensus project will seek to provide standard definitions for invasive fungal disease in critically ill adult patients.
T151 13244-13246 Sentence denotes 10
T152 13247-13418 Sentence denotes Our observations suggest increased risk for critically ill COVID‐19 patients to develop co‐infection with Aspergillus, which is likely to increase mortality rates further.
T153 13419-13595 Sentence denotes Therefore, testing for the presence of Aspergillus in lower respiratory secretions and galactomannan in consecutive serum samples in COVID‐19 ICU patients should be considered.
T154 13596-13598 Sentence denotes 11
T155 13599-13706 Sentence denotes Our findings need to be confirmed in clinical trials to elucidate the role of potential IPA after COVID‐19.
T156 13707-13820 Sentence denotes With this report, we aim to call attention to the critical phenomenon of COVID‐19 associated IA in ARDS patients.
T157 13822-13842 Sentence denotes CONFLICT OF INTEREST
T158 13843-14301 Sentence denotes PK has received non‐financial scientific grants from Miltenyi Biotec GmbH, Bergisch Gladbach, Germany, and the Cologne Excellence Cluster on Cellular Stress Responses in Aging‐Associated Diseases, University of Cologne, Cologne, Germany, and received lecture honoraria from Akademie für Infektionsmedizin e.V., Astellas Pharma, Gilead Sciences, GPR Academy Ruesselsheim, MSD Sharp & Dohme GmbH, and University Hospital, LMU Munich outside the submitted work.
T159 14302-15016 Sentence denotes OAC is supported by the German Federal Ministry of Research and Education, is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy—CECAD, EXC 2030—390 661 388 and has received research grants from, is an advisor to, or received lecture honoraria from Actelion, Allecra Therapeutics, Amplyx, Astellas, Basilea, Biosys UK Limited, Cidara, Da Volterra, Entasis, F2G, Gilead, Grupo Biotoscana, Janssen Pharmaceuticals, Matinas, Medicines Company, MedPace, Melinta Therapeutics, Menarini Ricerche, Roche Diagnostics, Merck/MSD, Nabriva Therapeutics, Octapharma, Paratek Pharmaceuticals, Pfizer, PSI, Rempex, Scynexis, Seres Therapeutics, Tetraphase, Vical.
T160 15017-15539 Sentence denotes BWB is European Resuscitation Council (ERC) Board Director Science and Research; Chairman of the German Resuscitation Council (GRC); Member of the Advanced Life Support (ALS) Task Force of the International Liaison Committee on Resuscitation (ILCOR); Member of the executive committee of the German Interdisciplinary Association for Intensive and Emergency Medicine (DIVI); Associated Editor of the European Journal of Anaesthesiology (EJA), Co‐Editor of ‘Resuscitation’; Editor of the Journal ‘Notfall + Rettungsmedizin’.
T161 15540-15612 Sentence denotes He received professional fees for lectures from the following companies:
T162 15613-15751 Sentence denotes Medupdate GmbH, ‘Forum für medizinische Fortbildung (FomF)’, Baxalta Deutschland GmbH, Bayer Vital GmbH, ZOLL Medical Deutschland GmbH, C.
T163 15752-15754 Sentence denotes R.
T164 15755-15798 Sentence denotes Bard GmbH, GS Elektromedizinische Geräte G.
T165 15799-15860 Sentence denotes Stemple GmbH, Novartis Pharma GmbH, Philips GmbH Market DACH.
T166 15861-16004 Sentence denotes FD reports personal fees from Forum für medizinische Fortbildung GmbH, BioMérieux GmBH, M3 Inc, and pm‐result GmbH, outside the submitted work.
T167 16005-16008 Sentence denotes FD:
T168 16009-16051 Sentence denotes Associated Editor of 'BMC Anesthesiology'.
T169 16052-16094 Sentence denotes DAE has no potential conflict of interest.
T170 16095-16242 Sentence denotes FF reports scientific grants from the Medical Faculty of the University of Cologne (Maria Pesch grant and GEROK grant), outside the submitted work.
T171 16243-16748 Sentence denotes MH reports grants from Roche, personal fees from Roche, personal fees from Roche, grants from Abbvie, personal fees from Abbvie, personal fees from Abbvie, during the conduct of the study; grants from Gilead, personal fees from Gilead, personal fees from Gilead, grants from Janssen, personal fees from Janssen, personal fees from Janssen, personal fees from Celgene, personal fees from Celgene, personal fees from Boehringer Ingelheim, personal fees from Boehringer Ingelheim, outside the submitted work.
T172 16749-16894 Sentence denotes NJ reports lecture fees from Gilead, Infectopharm and MSD and travel grants from Gilead, Basilea, Correvio and Pfizer outside the submitted work.
T173 16895-17108 Sentence denotes FK is supported by the German Center for Infection Research (DZIF), the German Research Foundation (CRC 1279 and CRC 1310), the Bill and Melinda Gates Foundation, and the European Research Council (ERC‐StG639961).
T174 17109-17206 Sentence denotes FK received lecture and consulting honoraria from MSD, Roche and ViiV outside the submitted work.
T175 17207-17248 Sentence denotes TP has no potential conflict of interest.
T176 17249-17276 Sentence denotes JR has nothing to disclose.
T177 17277-17402 Sentence denotes MK reports personal fees from Pfizer, Astellas Pharma, Gilead Sciences and MSD Sharp & Dohme GmbH outside the submitted work.
T178 17403-17581 Sentence denotes BB is a consultant to Baxalta, Celgene, MSD, Mundipharma and received Honoraria and Research funding from Astellas, Celgene, J&J, Maquet, Miltenyi, MSD, Takeda, Roche and Sanofi.
T179 17582-17656 Sentence denotes ASV reports travel grants from Gilead Sciences outside the submitted work.
T180 17658-17678 Sentence denotes AUTHOR CONTRIBUTIONS
T181 17679-17695 Sentence denotes Philipp Koehler:
T182 17696-17807 Sentence denotes Conceptualization (lead); Investigation (lead); Writing‐original draft (lead); Writing‐review & editing (lead).
T183 17808-17817 Sentence denotes Oliver A.
T184 17818-17826 Sentence denotes Cornely:
T185 17827-17938 Sentence denotes Conceptualization (lead); Investigation (lead); Writing‐original draft (lead); Writing‐review & editing (lead).
T186 17939-17947 Sentence denotes Bernd W.
T187 17948-17957 Sentence denotes Böttiger:
T188 17958-18061 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T189 18062-18075 Sentence denotes Fabian Dusse:
T190 18076-18179 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T191 18180-18189 Sentence denotes Dennis A.
T192 18190-18201 Sentence denotes Eichenauer:
T193 18202-18305 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T194 18306-18320 Sentence denotes Frieder Fuchs:
T195 18321-18424 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T196 18425-18440 Sentence denotes Michael Hallek:
T197 18441-18544 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T198 18545-18556 Sentence denotes Norma Jung:
T199 18557-18660 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T200 18661-18675 Sentence denotes Florian Klein:
T201 18676-18779 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T202 18780-18799 Sentence denotes Thorsten Persigehl:
T203 18800-18903 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T204 18904-18917 Sentence denotes Jan Rybniker:
T205 18918-19021 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T206 19022-19040 Sentence denotes Matthias Kochanek:
T207 19041-19144 Sentence denotes Investigation (supporting); Writing‐original draft (supporting); Writing‐review & editing (supporting).
T208 19145-19156 Sentence denotes Boris Böll:
T209 19157-19242 Sentence denotes Investigation (lead); Writing‐original draft (lead); Writing‐review & editing (lead).
T210 19243-19275 Sentence denotes Alexander Shimabukuro‐Vornhagen:
T211 19276-19361 Sentence denotes Investigation (lead); Writing‐original draft (lead); Writing‐review & editing (lead).
T212 19363-19379 Sentence denotes ETHICAL APPROVAL
T213 19380-19504 Sentence denotes The authors confirm that the ethical policies of the journal, as noted in the author's guideline page, have been adhered to.
T214 19505-19656 Sentence denotes Our study was approved by the ethic committee of the University Hospital of Cologne (Identifier of the University of Cologne Ethics Committee 20‐1157).
T215 19658-19680 Sentence denotes Supporting information
T216 19681-19689 Sentence denotes Video S1
T217 19690-19726 Sentence denotes Click here for additional data file.
T218 19727-19735 Sentence denotes Video S2
T219 19736-19772 Sentence denotes Click here for additional data file.
T220 19773-19781 Sentence denotes Video S3
T221 19782-19818 Sentence denotes Click here for additional data file.
T222 19819-19827 Sentence denotes Video S4
T223 19828-19864 Sentence denotes Click here for additional data file.
T224 19865-19873 Sentence denotes Video S5
T225 19874-19910 Sentence denotes Click here for additional data file.
T226 19911-19933 Sentence denotes Supplementary Material
T227 19934-19970 Sentence denotes Click here for additional data file.
T228 19972-19986 Sentence denotes ACKNOWLEDGMENT
T229 19987-20047 Sentence denotes The authors thank Susann Blossfeld for technical assistance.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 108-128 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T2 591-623 Phenotype denotes invasive pulmonary aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T3 799-831 Phenotype denotes invasive pulmonary aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T4 1118-1150 Phenotype denotes invasive pulmonary aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T5 1152-1155 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T6 1237-1257 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T7 1493-1502 Phenotype denotes paralysis http://purl.obolibrary.org/obo/HP_0003470
T8 1546-1553 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T9 2108-2140 Phenotype denotes invasive pulmonary aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T10 2328-2341 Phenotype denotes cholecystitis http://purl.obolibrary.org/obo/HP_0001082
T11 2351-2363 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T12 2364-2371 Phenotype denotes Obesity http://purl.obolibrary.org/obo/HP_0001513
T13 2377-2388 Phenotype denotes sleep apnea http://purl.obolibrary.org/obo/HP_0010535
T14 2400-2420 Phenotype denotes Hypercholesterolemia http://purl.obolibrary.org/obo/HP_0003124
T15 2464-2468 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T16 2582-2594 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T17 2595-2612 Phenotype denotes Diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T18 2613-2621 Phenotype denotes Aneurysm http://purl.obolibrary.org/obo/HP_0002617
T19 2661-2673 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T20 2682-2691 Phenotype denotes Emphysema http://purl.obolibrary.org/obo/HP_0002097
T21 2706-2710 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T22 2729-2738 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T23 2814-2818 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T24 2917-2921 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T25 3172-3191 Phenotype denotes Acute renal failure http://purl.obolibrary.org/obo/HP_0001919
T26 3989-3992 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T27 4989-5006 Phenotype denotes air crescent sign http://purl.obolibrary.org/obo/HP_0032172
T28 5092-5101 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T29 5986-6006 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T30 6070-6074 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T31 6076-6113 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T32 6200-6206 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T33 6264-6288 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T34 6319-6322 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T35 6324-6356 Phenotype denotes invasive pulmonary aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T36 8215-8218 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T37 8460-8486 Phenotype denotes Severe SARS‐CoV2 infection http://purl.obolibrary.org/obo/HP_0033141
T38 8538-8554 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T39 9007-9016 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T40 9687-9719 Phenotype denotes Invasive Pulmonary Aspergillosis http://purl.obolibrary.org/obo/HP_0020103
T41 10028-10045 Phenotype denotes air crescent sign http://purl.obolibrary.org/obo/HP_0032172
T42 10070-10079 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T43 10732-10751 Phenotype denotes acute renal failure http://purl.obolibrary.org/obo/HP_0001919
T44 10808-10830 Phenotype denotes elevated liver enzymes http://purl.obolibrary.org/obo/HP_0002910
T45 11175-11192 Phenotype denotes air crescent sign http://purl.obolibrary.org/obo/HP_0032172
T46 11464-11473 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T47 12263-12279 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T48 12308-12311 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T49 12481-12492 Phenotype denotes haemoptysis http://purl.obolibrary.org/obo/HP_0002105
T50 12522-12525 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T51 12583-12586 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T52 12654-12657 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103
T53 12818-12824 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T54 13687-13690 Phenotype denotes IPA http://purl.obolibrary.org/obo/HP_0020103