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PMC:7264098 / 14565-16505 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T261 41-51 CL:0000034 denotes stem cells
T262 73-83 SP_7 denotes SARS-CoV-2
T4839 41-51 CL:0000034 denotes stem cells
T89150 73-83 SP_7 denotes SARS-CoV-2

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
338 431-436 Gene denotes TNF-α Gene:7124
339 448-453 Gene denotes IL-10 Gene:3586
340 458-462 Gene denotes VEGF Gene:7422
341 126-134 Species denotes patients Tax:9606
342 210-221 Species denotes unspecified Tax:32644
343 267-275 Species denotes patients Tax:9606
344 585-593 Species denotes patients Tax:9606
345 716-724 Species denotes patients Tax:9606
346 861-869 Species denotes patients Tax:9606
347 1024-1032 Species denotes patients Tax:9606
348 1107-1118 Species denotes unspecified Tax:32644
349 1172-1180 Species denotes patients Tax:9606
350 1312-1320 Species denotes patients Tax:9606
351 1471-1479 Species denotes patients Tax:9606
352 1591-1599 Species denotes patients Tax:9606
353 1662-1667 Species denotes Human Tax:9606
354 1815-1823 Species denotes patients Tax:9606
355 288-306 Disease denotes COVID-19 pneumonia MESH:C000657245
357 73-93 Disease denotes SARS-CoV-2 infection MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T90 41-51 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T91 46-51 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T92 95-99 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T93 196-202 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T94 247-252 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T95 355-361 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T96 373-380 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T97 390-398 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T98 416-421 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T99 493-507 Body_part denotes Adipose tissue http://purl.org/sig/ont/fma/fma20110
T100 552-557 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T101 641-652 Body_part denotes Dental pulp http://purl.org/sig/ont/fma/fma55631
T102 653-663 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T103 658-663 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T104 673-678 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T105 779-790 Body_part denotes Dental pulp http://purl.org/sig/ont/fma/fma55631
T106 791-801 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T107 796-801 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T108 811-816 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 923-938 Body_part denotes Wharton's Jelly http://purl.org/sig/ont/fma/fma323134
T110 964-969 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T111 1093-1099 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T112 1129-1134 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T113 1235-1249 Body_part denotes Umbilical cord http://purl.org/sig/ont/fma/fma85541
T114 1266-1271 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T115 1375-1389 Body_part denotes Umbilical cord http://purl.org/sig/ont/fma/fma85541
T116 1406-1411 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 1419-1423 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T118 1518-1529 Body_part denotes Bone Marrow http://purl.org/sig/ont/fma/fma9608
T119 1559-1564 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T120 1668-1688 Body_part denotes embryonic stem cells http://purl.org/sig/ont/fma/fma82841
T121 1683-1688 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T122 1715-1720 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T123 1773-1778 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T124 1786-1790 Body_part denotes body http://purl.org/sig/ont/fma/fma256135

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T25 196-202 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T26 493-507 Body_part denotes Adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013
T27 501-507 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T28 641-652 Body_part denotes Dental pulp http://purl.obolibrary.org/obo/UBERON_0001754
T29 779-790 Body_part denotes Dental pulp http://purl.obolibrary.org/obo/UBERON_0001754
T30 1093-1099 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T31 1235-1249 Body_part denotes Umbilical cord http://purl.obolibrary.org/obo/UBERON_0002331
T32 1375-1389 Body_part denotes Umbilical cord http://purl.obolibrary.org/obo/UBERON_0002331
T33 1518-1529 Body_part denotes Bone Marrow http://purl.obolibrary.org/obo/UBERON_0002371

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T111 73-81 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 73-77 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T113 84-93 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T114 288-296 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T115 297-306 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T143 41-51 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T144 95-104 http://purl.obolibrary.org/obo/CL_0000000 denotes Cell type
T145 247-252 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T146 355-361 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T147 416-421 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T148 493-507 http://purl.obolibrary.org/obo/UBERON_0001013 denotes Adipose tissue
T149 552-557 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T150 597-598 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T151 653-663 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T152 673-678 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T153 728-729 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T154 791-801 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T155 811-816 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T156 873-874 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T157 964-969 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T158 977-982 http://purl.obolibrary.org/obo/CLO_0006976 denotes IV, 3
T159 1036-1037 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T160 1129-1134 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T161 1184-1185 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T162 1235-1249 http://purl.obolibrary.org/obo/UBERON_0002331 denotes Umbilical cord
T163 1235-1249 http://www.ebi.ac.uk/efo/EFO_0001415 denotes Umbilical cord
T164 1266-1271 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T165 1285-1289 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3, 5
T166 1324-1325 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T167 1375-1389 http://purl.obolibrary.org/obo/UBERON_0002331 denotes Umbilical cord
T168 1375-1389 http://www.ebi.ac.uk/efo/EFO_0001415 denotes Umbilical cord
T169 1406-1411 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T170 1444-1448 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3, 5
T171 1468-1470 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T172 1483-1484 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T173 1518-1522 http://purl.obolibrary.org/obo/UBERON_0002481 denotes Bone
T174 1559-1564 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T175 1603-1604 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T176 1662-1667 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T177 1678-1688 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T178 1715-1720 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T179 1753-1757 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3, 5
T180 1773-1778 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T181 1827-1828 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T45 261-263 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T46 373-380 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T47 448-450 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T49 566-568 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T50 679-681 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T51 824-826 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T52 977-979 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T53 1135-1137 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T54 1272-1274 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T55 1431-1433 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T56 1573-1575 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T57 1798-1800 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T20 308-343 http://purl.obolibrary.org/obo/GO_0050727 denotes Regulation of inflammatory response
T21 322-343 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T22 390-408 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine-secreting

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T79 0-94 Sentence denotes Table 1 Selected clinical studies using stem cells for the treatment of SARS-CoV-2 infection.
T80 95-189 Sentence denotes Cell type Dosage Number of patients Outcome Stage of study Reference or NCT numbers#
T81 190-492 Sentence denotes MSCs (tissue source unspecified) Single dose of 1 × 106 cells per kg, IV 7 patients with severe COVID-19 pneumonia Regulation of inflammatory response (Decreased plasma C-reaction protein, reduced cytokine-secreting immune cells, reduced TNF-α, increased IL-10 and VEGF) Complete Leng et al., 2020
T82 493-580 Sentence denotes Adipose tissue-derived MSCs Two serial doses of 1.5 × 106 cells per kg, IV Estimated:
T83 581-640 Sentence denotes 100 patients N/A Phase 2; Not yet recruiting NCT04348461
T84 641-712 Sentence denotes Dental pulp stem cells 3 × 107 cells IV on day 1, 4, and 7 Estimated:
T85 713-778 Sentence denotes 20 patients N/A Phase 1 clinical trial; recruiting NCT04336254
T86 779-857 Sentence denotes Dental pulp stem cells 1 × 106 cells per kg IV on day 1, 3, and 7 Estimated:
T87 858-922 Sentence denotes 24 patients N/A Early Phase 1; Not yet recruiting NCT04302519
T88 923-1021 Sentence denotes Wharton's Jelly MSCs 3 doses of 1 × 106 cells per kg IV, 3 days apart from each other Estimated:
T89 1022-1086 Sentence denotes 5 patients N/A Phase 1 clinical trial; recruiting NCT04313322
T90 1087-1168 Sentence denotes MSCs (tissue source unspecified) 3 × 107 cells IV on day 0, 3, and 6 Estimated:
T91 1169-1234 Sentence denotes 20 patients N/A Phase 1 clinical trial; recruiting NCT04252118
T92 1235-1308 Sentence denotes Umbilical cord MSCs 9.9 × 107 cells IV on day 1, 3, 5, and 7 Estimated:
T93 1309-1374 Sentence denotes 10 patients N/A Phase 2 clinical trial; recruiting NCT04269525
T94 1375-1467 Sentence denotes Umbilical cord MSCs 0.5 × 106 cells per kg body weight IV on day 1, 3, 5, and 7 Estimated:
T95 1468-1517 Sentence denotes 48 patients N/A Not yet recruiting NCT04273646
T96 1518-1587 Sentence denotes Bone Marrow MSCs Single dose of 1 × 106 cells per kg, IV Estimated:
T97 1588-1661 Sentence denotes 20 patients N/A Phase 1 clinical trial; Not yet recruiting NCT04346368
T98 1662-1812 Sentence denotes Human embryonic stem cells derived matrix-regulatory cells 3 cohorts who receive doses of 3, 5, or 10 million cells per kg body weight IV Estimated:
T99 1813-1877 Sentence denotes 9 patients N/A Phase 1 clinical trial; recruiting NCT04331613
T100 1878-1940 Sentence denotes # NCT numbers refer to ClinicalTrials.gov Identifier numbers.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T14 297-306 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

2_test

Id Subject Object Predicate Lexical cue
32574317-32257537-31466323 488-492 32257537 denotes 2020

MyTest

Id Subject Object Predicate Lexical cue
32574317-32257537-31466323 488-493 32257537 denotes 2020