PMC:7261349 / 5446-6496 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T33","span":{"begin":49,"end":56},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T34","span":{"begin":49,"end":56},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"},{"id":"T35","span":{"begin":155,"end":162},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T36","span":{"begin":155,"end":162},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"},{"id":"T37","span":{"begin":243,"end":250},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T38","span":{"begin":243,"end":250},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"}],"text":"The age of patients treated and not treated with heparin was compared with t tests. The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests. The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender. Second, two markers of severity, temperature \u003e 37 °C and saturation of oxygen \u003c 90% on admission, were introduced into the model as well. Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model. Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis. Stata 14 was used for the analysis [11]. The ethics committee of HM Hospitales approved this study. Data were anonymized before the authors could access it."}

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T23","span":{"begin":49,"end":56},"obj":"Body_part"},{"id":"T24","span":{"begin":155,"end":162},"obj":"Body_part"},{"id":"T25","span":{"begin":243,"end":250},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma82839"}],"text":"The age of patients treated and not treated with heparin was compared with t tests. The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests. The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender. Second, two markers of severity, temperature \u003e 37 °C and saturation of oxygen \u003c 90% on admission, were introduced into the model as well. Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model. Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis. Stata 14 was used for the analysis [11]. The ethics committee of HM Hospitales approved this study. Data were anonymized before the authors could access it."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T14","span":{"begin":77,"end":82},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T15","span":{"begin":193,"end":198},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T16","span":{"begin":283,"end":284},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T17","span":{"begin":575,"end":576},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T18","span":{"begin":930,"end":932},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"}],"text":"The age of patients treated and not treated with heparin was compared with t tests. The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests. The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender. Second, two markers of severity, temperature \u003e 37 °C and saturation of oxygen \u003c 90% on admission, were introduced into the model as well. Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model. Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis. Stata 14 was used for the analysis [11]. The ethics committee of HM Hospitales approved this study. Data were anonymized before the authors could access it."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T38","span":{"begin":49,"end":56},"obj":"Chemical"},{"id":"T39","span":{"begin":155,"end":162},"obj":"Chemical"},{"id":"T40","span":{"begin":243,"end":250},"obj":"Chemical"},{"id":"T41","span":{"begin":426,"end":432},"obj":"Chemical"},{"id":"T42","span":{"begin":518,"end":536},"obj":"Chemical"},{"id":"T43","span":{"begin":538,"end":550},"obj":"Chemical"},{"id":"T44","span":{"begin":552,"end":560},"obj":"Chemical"},{"id":"T45","span":{"begin":562,"end":573},"obj":"Chemical"},{"id":"T46","span":{"begin":592,"end":601},"obj":"Chemical"},{"id":"T47","span":{"begin":607,"end":616},"obj":"Chemical"},{"id":"T48","span":{"begin":621,"end":632},"obj":"Chemical"},{"id":"T49","span":{"begin":959,"end":961},"obj":"Chemical"}],"attributes":[{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A40","pred":"chebi_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A44","pred":"chebi_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/CHEBI_35341"},{"id":"A45","pred":"chebi_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_64360"},{"id":"A46","pred":"chebi_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A47","pred":"chebi_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A48","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_7798"},{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_74053"}],"text":"The age of patients treated and not treated with heparin was compared with t tests. The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests. The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender. Second, two markers of severity, temperature \u003e 37 °C and saturation of oxygen \u003c 90% on admission, were introduced into the model as well. Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model. Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis. Stata 14 was used for the analysis [11]. The ethics committee of HM Hospitales approved this study. Data were anonymized before the authors could access it."}

{"project":"LitCovid-sentences","denotations":[{"id":"T45","span":{"begin":0,"end":83},"obj":"Sentence"},{"id":"T46","span":{"begin":84,"end":199},"obj":"Sentence"},{"id":"T47","span":{"begin":200,"end":354},"obj":"Sentence"},{"id":"T48","span":{"begin":355,"end":492},"obj":"Sentence"},{"id":"T49","span":{"begin":493,"end":658},"obj":"Sentence"},{"id":"T50","span":{"begin":659,"end":893},"obj":"Sentence"},{"id":"T51","span":{"begin":894,"end":934},"obj":"Sentence"},{"id":"T52","span":{"begin":935,"end":993},"obj":"Sentence"},{"id":"T53","span":{"begin":994,"end":1050},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The age of patients treated and not treated with heparin was compared with t tests. The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests. The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender. Second, two markers of severity, temperature \u003e 37 °C and saturation of oxygen \u003c 90% on admission, were introduced into the model as well. Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model. Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis. Stata 14 was used for the analysis [11]. The ethics committee of HM Hospitales approved this study. Data were anonymized before the authors could access it."}