PMC:7261349 / 4269-5445 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T31","span":{"begin":661,"end":668},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T32","span":{"begin":661,"end":668},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-PubTator","denotations":[{"id":"154","span":{"begin":65,"end":73},"obj":"Species"},{"id":"155","span":{"begin":299,"end":307},"obj":"Species"},{"id":"156","span":{"begin":390,"end":400},"obj":"Species"},{"id":"157","span":{"begin":461,"end":469},"obj":"Species"},{"id":"158","span":{"begin":569,"end":575},"obj":"Chemical"},{"id":"159","span":{"begin":661,"end":668},"obj":"Chemical"},{"id":"160","span":{"begin":670,"end":688},"obj":"Chemical"},{"id":"161","span":{"begin":690,"end":702},"obj":"Chemical"},{"id":"162","span":{"begin":704,"end":712},"obj":"Chemical"},{"id":"163","span":{"begin":714,"end":725},"obj":"Chemical"},{"id":"164","span":{"begin":744,"end":753},"obj":"Chemical"},{"id":"165","span":{"begin":774,"end":785},"obj":"Chemical"},{"id":"166","span":{"begin":90,"end":98},"obj":"Disease"},{"id":"167","span":{"begin":1152,"end":1161},"obj":"Disease"}],"attributes":[{"id":"A154","pred":"tao:has_database_id","subj":"154","obj":"Tax:9606"},{"id":"A155","pred":"tao:has_database_id","subj":"155","obj":"Tax:9606"},{"id":"A156","pred":"tao:has_database_id","subj":"156","obj":"Tax:2697049"},{"id":"A157","pred":"tao:has_database_id","subj":"157","obj":"Tax:9606"},{"id":"A158","pred":"tao:has_database_id","subj":"158","obj":"MESH:D010100"},{"id":"A159","pred":"tao:has_database_id","subj":"159","obj":"MESH:D006493"},{"id":"A160","pred":"tao:has_database_id","subj":"160","obj":"MESH:D006886"},{"id":"A161","pred":"tao:has_database_id","subj":"161","obj":"MESH:D017963"},{"id":"A162","pred":"tao:has_database_id","subj":"162","obj":"MESH:D013256"},{"id":"A163","pred":"tao:has_database_id","subj":"163","obj":"MESH:C502936"},{"id":"A164","pred":"tao:has_database_id","subj":"164","obj":"MESH:D061466"},{"id":"A165","pred":"tao:has_database_id","subj":"165","obj":"MESH:D053139"},{"id":"A166","pred":"tao:has_database_id","subj":"166","obj":"MESH:C000657245"},{"id":"A167","pred":"tao:has_database_id","subj":"167","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T22","span":{"begin":661,"end":668},"obj":"Body_part"}],"attributes":[{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma82839"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":390,"end":398},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T11","span":{"begin":286,"end":292},"obj":"http://purl.obolibrary.org/obo/CLO_0009382"},{"id":"T12","span":{"begin":358,"end":362},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T13","span":{"begin":727,"end":728},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T26","span":{"begin":161,"end":163},"obj":"Chemical"},{"id":"T27","span":{"begin":569,"end":575},"obj":"Chemical"},{"id":"T28","span":{"begin":661,"end":668},"obj":"Chemical"},{"id":"T29","span":{"begin":670,"end":688},"obj":"Chemical"},{"id":"T30","span":{"begin":690,"end":702},"obj":"Chemical"},{"id":"T31","span":{"begin":704,"end":712},"obj":"Chemical"},{"id":"T32","span":{"begin":714,"end":725},"obj":"Chemical"},{"id":"T33","span":{"begin":744,"end":753},"obj":"Chemical"},{"id":"T34","span":{"begin":759,"end":768},"obj":"Chemical"},{"id":"T35","span":{"begin":774,"end":785},"obj":"Chemical"},{"id":"T36","span":{"begin":925,"end":930},"obj":"Chemical"},{"id":"T37","span":{"begin":1114,"end":1119},"obj":"Chemical"}],"attributes":[{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_74053"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_35341"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_64360"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_7798"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}

{"project":"LitCovid-sentences","denotations":[{"id":"T37","span":{"begin":0,"end":190},"obj":"Sentence"},{"id":"T38","span":{"begin":191,"end":298},"obj":"Sentence"},{"id":"T39","span":{"begin":299,"end":454},"obj":"Sentence"},{"id":"T40","span":{"begin":455,"end":517},"obj":"Sentence"},{"id":"T41","span":{"begin":518,"end":802},"obj":"Sentence"},{"id":"T42","span":{"begin":803,"end":1005},"obj":"Sentence"},{"id":"T43","span":{"begin":1006,"end":1134},"obj":"Sentence"},{"id":"T44","span":{"begin":1135,"end":1176},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed. These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10]. Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020. Seven patients had been admitted before the 1st of March 2020. Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected. The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency. No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected. Finally, data on mortality were recorded."}