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PMC:7261349 / 4261-6496 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T31 669-676 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T32 669-676 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T33 1234-1241 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T34 1234-1241 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T35 1340-1347 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T36 1340-1347 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T37 1428-1435 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T38 1428-1435 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
154 73-81 Species denotes patients Tax:9606
155 307-315 Species denotes Patients Tax:9606
156 398-408 Species denotes SARS-CoV-2 Tax:2697049
157 469-477 Species denotes patients Tax:9606
158 577-583 Chemical denotes oxygen MESH:D010100
159 669-676 Chemical denotes heparin MESH:D006493
160 678-696 Chemical denotes hydroxychloroquine MESH:D006886
161 698-710 Chemical denotes azithromycin MESH:D017963
162 712-720 Chemical denotes steroids MESH:D013256
163 722-733 Chemical denotes tocilizumab MESH:C502936
164 752-761 Chemical denotes lopinavir MESH:D061466
165 782-793 Chemical denotes oseltamivir MESH:D053139
166 98-106 Disease denotes Covid-19 MESH:C000657245
167 1160-1169 Disease denotes mortality MESH:D003643
183 1196-1204 Species denotes patients Tax:9606
184 1287-1290 Species denotes men Tax:9606
185 1295-1300 Species denotes women Tax:9606
186 1234-1241 Chemical denotes heparin MESH:D006493
187 1340-1347 Chemical denotes heparin MESH:D006493
188 1428-1435 Chemical denotes heparin MESH:D006493
189 1611-1617 Chemical denotes oxygen MESH:D010100
190 1703-1721 Chemical denotes hydroxychloroquine MESH:D006886
191 1723-1735 Chemical denotes azithromycin MESH:D017963
192 1737-1745 Chemical denotes steroids MESH:D013256
193 1747-1758 Chemical denotes tocilizumab MESH:C502936
194 1777-1786 Chemical denotes lopinavir MESH:D061466
195 1792-1801 Chemical denotes ritonavir MESH:D019438
196 1806-1817 Chemical denotes oseltamivir MESH:D053139
197 1440-1449 Disease denotes mortality MESH:D003643

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T22 669-676 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T23 1234-1241 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T24 1340-1347 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T25 1428-1435 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T7 398-406 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T11 294-300 http://purl.obolibrary.org/obo/CLO_0009382 denotes Toledo
T12 366-370 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T13 735-736 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 1262-1267 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T15 1378-1383 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T16 1468-1469 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 1760-1761 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T18 2115-2117 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T26 169-171 Chemical denotes HM http://purl.obolibrary.org/obo/CHEBI_74053
T27 577-583 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T28 669-676 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T29 678-696 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T30 698-710 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T31 712-720 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T32 722-733 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T33 752-761 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T34 767-776 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T35 782-793 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T36 933-938 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T37 1122-1127 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T38 1234-1241 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T39 1340-1347 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T40 1428-1435 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T41 1611-1617 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T42 1703-1721 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T43 1723-1735 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T44 1737-1745 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T45 1747-1758 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T46 1777-1786 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T47 1792-1801 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T48 1806-1817 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T49 2144-2146 Chemical denotes HM http://purl.obolibrary.org/obo/CHEBI_74053

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T36 0-7 Sentence denotes Methods
T37 8-198 Sentence denotes Anonymized clinical records up to the 24th of April 2020, of all patients (n = 2075) with Covid-19, admitted in 17 Spanish hospitals, of the healthcare provider HM Hospitales, were reviewed.
T38 199-306 Sentence denotes These hospitals are based in the provinces of Barcelona, Coruña, León, Madrid, Pontevedra, and Toledo [10].
T39 307-462 Sentence denotes Patients had been diagnosed with polymerase chain reaction test of respiratory samples for SARS-CoV-2, between the 1st of March and the 20th of April 2020.
T40 463-525 Sentence denotes Seven patients had been admitted before the 1st of March 2020.
T41 526-810 Sentence denotes Data on age, gender, temperature and saturation of oxygen at the time of admission, together with treatments at any time during admission with heparin, hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, were collected.
T42 811-1013 Sentence denotes The limited evidence on which these treatments were based, and the rapidly evolving clinical protocols, resulted in these drugs being given in many different specific preparations, doses, and frequency.
T43 1014-1142 Sentence denotes No information on dosage, duration of treatment, route of administration, or specific preparations of these drugs was collected.
T44 1143-1184 Sentence denotes Finally, data on mortality were recorded.
T45 1185-1268 Sentence denotes The age of patients treated and not treated with heparin was compared with t tests.
T46 1269-1384 Sentence denotes The proportion of men and women for those treated and not treated with heparin was compared with chi squared tests.
T47 1385-1539 Sentence denotes The association between the treatment with heparin and mortality was examined with a logistic regression model that was first adjusted for age and gender.
T48 1540-1677 Sentence denotes Second, two markers of severity, temperature > 37 °C and saturation of oxygen < 90% on admission, were introduced into the model as well.
T49 1678-1843 Sentence denotes Finally, treatments with hydroxychloroquine, azithromycin, steroids, tocilizumab, a combination of lopinavir with ritonavir, or oseltamivir, were added to the model.
T50 1844-2078 Sentence denotes Sensitivity analyses were made to compare estimates based on using missing data of severity markers as categories with, (1) estimates based on complete data dropping variables with missing observations, and (2) complete case analysis.
T51 2079-2119 Sentence denotes Stata 14 was used for the analysis [11].
T52 2120-2178 Sentence denotes The ethics committee of HM Hospitales approved this study.
T53 2179-2235 Sentence denotes Data were anonymized before the authors could access it.