PMC:7258756 / 35104-36491
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 534 | 516-521 | Gene | denotes | IFN-γ | Gene:3458 |
| 535 | 381-386 | Gene | denotes | spike | Gene:43740568 |
| 536 | 44-49 | Gene | denotes | spike | Gene:43740568 |
| 537 | 10-18 | Species | denotes | SARS-CoV | Tax:694009 |
| 538 | 684-692 | Species | denotes | SARS-CoV | Tax:694009 |
| 539 | 1000-1008 | Species | denotes | SARS-CoV | Tax:694009 |
| 540 | 1293-1303 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 541 | 1308-1316 | Species | denotes | SARS-CoV | Tax:694009 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T236 | 30-38 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T237 | 50-57 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T238 | 160-164 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T239 | 305-309 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T240 | 387-394 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T241 | 697-704 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T242 | 1064-1068 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T243 | 1169-1173 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T192 | 10-18 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T193 | 10-14 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T194 | 684-692 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T195 | 684-688 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T196 | 1000-1008 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T197 | 1000-1004 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T198 | 1293-1301 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T199 | 1293-1297 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T200 | 1308-1316 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T201 | 1308-1312 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T280 | 58-61 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T281 | 158-164 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T282 | 238-240 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T283 | 263-265 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T284 | 263-265 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T285 | 303-309 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T286 | 503-504 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T287 | 585-586 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T288 | 708-709 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T289 | 791-794 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T290 | 945-946 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T291 | 977-980 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T292 | 1062-1068 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T293 | 1165-1166 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T294 | 1167-1173 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T295 | 1329-1332 | http://purl.obolibrary.org/obo/CLO_0001178 | denotes | 243 |
| T296 | 1329-1332 | http://purl.obolibrary.org/obo/CLO_0052433 | denotes | 243 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T150 | 30-38 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T151 | 50-57 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T152 | 263-265 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T153 | 387-394 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T154 | 619-626 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
| T155 | 697-704 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T156 | 740-747 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
| T157 | 783-790 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
| T158 | 969-976 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
| T159 | 1084-1091 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T26 | 808-830 | http://purl.obolibrary.org/obo/GO_0006487 | denotes | N-linked glycosylation |
| T27 | 817-830 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T232 | 0-109 | Sentence | denotes | Among the SARS-CoV structural proteins, the spike protein has been found to elicit neutralizing antibodies24. |
| T233 | 110-273 | Sentence | denotes | In this study, it was observed that of the five B-cell linear epitopes, which were predicted, four epitopes were present in the S1 domain and one in the S2 domain. |
| T234 | 274-595 | Sentence | denotes | Prediction of conformational B-cell epitopes revealed that one of these (residue positions 341-505) in the spike protein incorporates two of the predicted linear epitopes (327-342 and 404-419) having good antigenicity along with a favourable IFN-γ response that enables differentiation and proliferation of the B-cells25. |
| T235 | 596-719 | Sentence | denotes | Notably, an equivalent epitope (347-499) is predicted for the model generated using the SARS-CoV-1 S protein as a template. |
| T236 | 720-769 | Sentence | denotes | In both cases, this epitope lies within the RBD6. |
| T237 | 770-944 | Sentence | denotes | Although the epitope has two putative N-linked glycosylation sites within it at positions 330 and 332, the probability of these sites being actually glycosylated is very low. |
| T238 | 945-1040 | Sentence | denotes | A major immuno-dominant epitope has been reported from SARS-CoV between residues 441 and 70026. |
| T239 | 1041-1183 | Sentence | denotes | Hence, the predicted B-cell conformational epitope identified in the present study may play an important role in initiating a B-cell response. |
| T240 | 1184-1319 | Sentence | denotes | Among the five linear epitopes predicted in this study, epitopes 327-342 and 1204-1219 are conserved between SARS-CoV-2 and SARS-CoV-1. |
| T241 | 1320-1387 | Sentence | denotes | Epitopes 243-258, 404-419 and 413-428 are found to have variations. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32242873-15210961-47036572 | 106-108 | 15210961 | denotes | 24 |
| 32242873-9916700-47036573 | 592-594 | 9916700 | denotes | 25 |
| 32242873-32007145-47036574 | 767-768 | 32007145 | denotes | 6 |
| 32242873-26038429-47036575 | 1034-1039 | 26038429 | denotes | 70026 |
| T80103 | 106-108 | 15210961 | denotes | 24 |
| T68904 | 592-594 | 9916700 | denotes | 25 |
| T89340 | 767-768 | 32007145 | denotes | 6 |
| T29055 | 1034-1039 | 26038429 | denotes | 70026 |