PMC:7258756 / 19851-20459 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7258756","sourcedb":"PMC","sourceid":"7258756","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7258756","text":"ing multiple methods, Ellipro and DiscoTope. Conformational epitopes based on these methods were mapped on the pre-fusion structure of the modelled Indian SARS-CoV-2 spike protein. The newly released structure of the SARS-CoV-2 spike protein was used as the template for modelling the Indian spike protein. Ramachandran plot statistics revealed 83.7 per cent of the residues to be in the core region, 14.4 per cent in the additionally allowed region and 0.5 per cent in the disallowed region. Four epitopes were predicted by Ellipro based on the PI threshold of 0.8 (Supplementary Table II (available from ht","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"288","span":{"begin":292,"end":297},"obj":"Gene"},{"id":"289","span":{"begin":228,"end":233},"obj":"Gene"},{"id":"290","span":{"begin":166,"end":171},"obj":"Gene"},{"id":"293","span":{"begin":155,"end":165},"obj":"Species"},{"id":"294","span":{"begin":217,"end":227},"obj":"Species"}],"attributes":[{"id":"A288","pred":"tao:has_database_id","subj":"288","obj":"Gene:43740568"},{"id":"A289","pred":"tao:has_database_id","subj":"289","obj":"Gene:43740568"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"Gene:43740568"},{"id":"A293","pred":"tao:has_database_id","subj":"293","obj":"Tax:2697049"},{"id":"A294","pred":"tao:has_database_id","subj":"294","obj":"Tax:2697049"},{"subj":"288","pred":"source","obj":"LitCovid-PubTator"},{"subj":"289","pred":"source","obj":"LitCovid-PubTator"},{"subj":"290","pred":"source","obj":"LitCovid-PubTator"},{"subj":"293","pred":"source","obj":"LitCovid-PubTator"},{"subj":"294","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T99","span":{"begin":172,"end":179},"obj":"Body_part"},{"id":"T100","span":{"begin":234,"end":241},"obj":"Body_part"},{"id":"T101","span":{"begin":298,"end":305},"obj":"Body_part"}],"attributes":[{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T155","span":{"begin":155,"end":163},"obj":"Disease"},{"id":"T156","span":{"begin":155,"end":159},"obj":"Disease"},{"id":"T157","span":{"begin":217,"end":225},"obj":"Disease"},{"id":"T158","span":{"begin":217,"end":221},"obj":"Disease"}],"attributes":[{"id":"A155","pred":"mondo_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A156","pred":"mondo_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T155","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T156","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T100","span":{"begin":172,"end":179},"obj":"Chemical"},{"id":"T101","span":{"begin":234,"end":241},"obj":"Chemical"},{"id":"T102","span":{"begin":298,"end":305},"obj":"Chemical"},{"id":"T103","span":{"begin":546,"end":548},"obj":"Chemical"},{"id":"T107","span":{"begin":587,"end":589},"obj":"Chemical"}],"attributes":[{"id":"A100","pred":"chebi_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A101","pred":"chebi_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A102","pred":"chebi_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A103","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_28874"},{"id":"A104","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_53806"},{"id":"A105","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_61484"},{"id":"A106","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_74790"},{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T153","span":{"begin":45,"end":180},"obj":"Sentence"},{"id":"T154","span":{"begin":181,"end":306},"obj":"Sentence"},{"id":"T155","span":{"begin":307,"end":492},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T153","pred":"source","obj":"LitCovid-sentences"},{"subj":"T154","pred":"source","obj":"LitCovid-sentences"},{"subj":"T155","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93a4ec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#beec93"},{"id":"LitCovid-PD-MONDO","color":"#ec93d9"},{"id":"LitCovid-PD-CHEBI","color":"#93ece5"},{"id":"LitCovid-sentences","color":"#eccb93"}]}]}}