PMC:7253482 / 32923-34338 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7253482","sourcedb":"PMC","sourceid":"7253482","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7253482","text":"Molecular evolution analysis\nPublicly available sequences encoding full-length GPC spike gene for SARS-CoV (3765 bp) were downloaded from GenBank and manually aligned. For MERS-CoV, we leveraged the whole genome alignment collated by Dudas et al.69. Specifically, the alignment corresponding to the spike gene was extracted (4059 bp), excluding sequences isolated from humans. Final alignments for SARS- and MERS-CoV corresponded to 70 and 100 sequences, respectively.\nFor the dN/dS analysis, we first estimated Bayesian molecular clock phylogenies for SARS- and MERS-CoV independently using BEAST v 1.8.470. For both viruses, we assumed an uncorrelated log-normal distributed molecular clock71, Bayesian Skyline coalescent prior72 and a codon-structured substitution model73. Multiple independent MCMC runs of 10–20 million steps were executed to ensure that stationarity and convergence had been achieved. Empirical distributions of time-scaled phylogenies were obtained by combining (after the removal of burnin) the posterior tree distributions from the separate runs, which were subsequently used to estimate dN/dS ratios using the renaissance counting approach74,75 implemented in BEAST v 1.8.4. We also estimated per-site amino-acid diversity, which was calculated as the average number of amino-acid difference between two sequences at an amino-acid position in all possible pairs in the sequence alignment.","divisions":[{"label":"title","span":{"begin":0,"end":28}},{"label":"p","span":{"begin":29,"end":468}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"998","span":{"begin":79,"end":82},"obj":"Gene"},{"id":"999","span":{"begin":299,"end":304},"obj":"Gene"},{"id":"1000","span":{"begin":83,"end":88},"obj":"Gene"},{"id":"1001","span":{"begin":98,"end":106},"obj":"Species"},{"id":"1002","span":{"begin":172,"end":180},"obj":"Species"},{"id":"1003","span":{"begin":369,"end":375},"obj":"Species"},{"id":"1004","span":{"begin":408,"end":416},"obj":"Species"},{"id":"1005","span":{"begin":398,"end":402},"obj":"Disease"},{"id":"1010","span":{"begin":563,"end":571},"obj":"Species"},{"id":"1011","span":{"begin":1114,"end":1116},"obj":"Chemical"},{"id":"1012","span":{"begin":1117,"end":1119},"obj":"Chemical"},{"id":"1013","span":{"begin":553,"end":557},"obj":"Disease"}],"attributes":[{"id":"A998","pred":"tao:has_database_id","subj":"998","obj":"Gene:2995"},{"id":"A999","pred":"tao:has_database_id","subj":"999","obj":"Gene:43740568"},{"id":"A1000","pred":"tao:has_database_id","subj":"1000","obj":"Gene:43740568"},{"id":"A1001","pred":"tao:has_database_id","subj":"1001","obj":"Tax:694009"},{"id":"A1002","pred":"tao:has_database_id","subj":"1002","obj":"Tax:1335626"},{"id":"A1003","pred":"tao:has_database_id","subj":"1003","obj":"Tax:9606"},{"id":"A1004","pred":"tao:has_database_id","subj":"1004","obj":"Tax:1335626"},{"id":"A1005","pred":"tao:has_database_id","subj":"1005","obj":"MESH:D045169"},{"id":"A1010","pred":"tao:has_database_id","subj":"1010","obj":"Tax:1335626"},{"id":"A1011","pred":"tao:has_database_id","subj":"1011","obj":"MESH:C022306"},{"id":"A1012","pred":"tao:has_database_id","subj":"1012","obj":"MESH:D003903"},{"id":"A1013","pred":"tao:has_database_id","subj":"1013","obj":"MESH:D045169"},{"subj":"998","pred":"source","obj":"LitCovid-PubTator"},{"subj":"999","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1000","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1001","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1002","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1003","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1004","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1005","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1010","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1011","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1012","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1013","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T169","span":{"begin":89,"end":93},"obj":"Body_part"},{"id":"T170","span":{"begin":205,"end":211},"obj":"Body_part"},{"id":"T171","span":{"begin":305,"end":309},"obj":"Body_part"},{"id":"T172","span":{"begin":1229,"end":1239},"obj":"Body_part"},{"id":"T173","span":{"begin":1297,"end":1307},"obj":"Body_part"},{"id":"T174","span":{"begin":1347,"end":1357},"obj":"Body_part"}],"attributes":[{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma82739"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T99","span":{"begin":98,"end":106},"obj":"Disease"},{"id":"T100","span":{"begin":98,"end":102},"obj":"Disease"},{"id":"T101","span":{"begin":398,"end":402},"obj":"Disease"},{"id":"T102","span":{"begin":553,"end":557},"obj":"Disease"}],"attributes":[{"id":"A99","pred":"mondo_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A100","pred":"mondo_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A101","pred":"mondo_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A102","pred":"mondo_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T237","span":{"begin":89,"end":93},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T238","span":{"begin":305,"end":309},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T239","span":{"begin":369,"end":375},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T240","span":{"begin":618,"end":625},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T241","span":{"begin":736,"end":737},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T242","span":{"begin":1020,"end":1029},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"}],"attributes":[{"subj":"T237","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T238","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T239","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T240","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T241","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T242","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T357","span":{"begin":477,"end":479},"obj":"Chemical"},{"id":"T358","span":{"begin":1114,"end":1116},"obj":"Chemical"},{"id":"T359","span":{"begin":1229,"end":1234},"obj":"Chemical"},{"id":"T360","span":{"begin":1235,"end":1239},"obj":"Chemical"},{"id":"T361","span":{"begin":1297,"end":1302},"obj":"Chemical"},{"id":"T362","span":{"begin":1303,"end":1307},"obj":"Chemical"},{"id":"T363","span":{"begin":1347,"end":1352},"obj":"Chemical"},{"id":"T364","span":{"begin":1353,"end":1357},"obj":"Chemical"}],"attributes":[{"id":"A357","pred":"chebi_id","subj":"T357","obj":"http://purl.obolibrary.org/obo/CHEBI_33793"},{"id":"A358","pred":"chebi_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/CHEBI_33793"},{"id":"A359","pred":"chebi_id","subj":"T359","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A360","pred":"chebi_id","subj":"T360","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A361","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A362","pred":"chebi_id","subj":"T362","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A363","pred":"chebi_id","subj":"T363","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A364","pred":"chebi_id","subj":"T364","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"subj":"T357","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T358","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T359","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T360","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T361","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T362","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T363","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T364","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T92","span":{"begin":618,"end":625},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T93","span":{"begin":1224,"end":1228},"obj":"http://purl.obolibrary.org/obo/BFO_0000029"}],"attributes":[{"subj":"T92","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T93","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T167","span":{"begin":89,"end":93},"obj":"Body_part"},{"id":"T168","span":{"begin":205,"end":211},"obj":"Body_part"},{"id":"T169","span":{"begin":305,"end":309},"obj":"Body_part"},{"id":"T170","span":{"begin":1229,"end":1239},"obj":"Body_part"},{"id":"T171","span":{"begin":1297,"end":1307},"obj":"Body_part"},{"id":"T172","span":{"begin":1347,"end":1357},"obj":"Body_part"}],"attributes":[{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A168","pred":"fma_id","subj":"T168","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A167","pred":"fma_id","subj":"T167","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma82739"},{"subj":"T167","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T168","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T169","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T170","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T171","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T172","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T251","span":{"begin":1229,"end":1234},"obj":"Chemical"},{"id":"T252","span":{"begin":1297,"end":1302},"obj":"Chemical"},{"id":"T253","span":{"begin":1347,"end":1352},"obj":"Chemical"}],"attributes":[{"id":"A252","pred":"chebi_id","subj":"T252","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A253","pred":"chebi_id","subj":"T253","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A251","pred":"chebi_id","subj":"T251","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"subj":"T251","pred":"source","obj":"LitCovid-sample-CHEBI"},{"subj":"T252","pred":"source","obj":"LitCovid-sample-CHEBI"},{"subj":"T253","pred":"source","obj":"LitCovid-sample-CHEBI"}]},{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T205","span":{"begin":98,"end":106},"obj":"Species"},{"id":"T206","span":{"begin":98,"end":102},"obj":"Species"},{"id":"T207","span":{"begin":172,"end":180},"obj":"Species"},{"id":"T208","span":{"begin":369,"end":375},"obj":"Species"},{"id":"T209","span":{"begin":398,"end":402},"obj":"Species"},{"id":"T210","span":{"begin":408,"end":416},"obj":"Species"},{"id":"T211","span":{"begin":553,"end":557},"obj":"Species"},{"id":"T212","span":{"begin":563,"end":571},"obj":"Species"},{"id":"T213","span":{"begin":618,"end":625},"obj":"Species"},{"id":"T214","span":{"begin":738,"end":743},"obj":"Species"}],"attributes":[{"id":"A211","pred":"ncbi_taxonomy_id","subj":"T211","obj":"NCBItxid:694009"},{"id":"A207","pred":"ncbi_taxonomy_id","subj":"T207","obj":"NCBItxid:1335626"},{"id":"A210","pred":"ncbi_taxonomy_id","subj":"T210","obj":"NCBItxid:1335626"},{"id":"A212","pred":"ncbi_taxonomy_id","subj":"T212","obj":"NCBItxid:1335626"},{"id":"A206","pred":"ncbi_taxonomy_id","subj":"T206","obj":"NCBItxid:694009"},{"id":"A213","pred":"ncbi_taxonomy_id","subj":"T213","obj":"NCBItxid:10239"},{"id":"A205","pred":"ncbi_taxonomy_id","subj":"T205","obj":"NCBItxid:694009"},{"id":"A214","pred":"ncbi_taxonomy_id","subj":"T214","obj":"NCBItxid:79338"},{"id":"A208","pred":"ncbi_taxonomy_id","subj":"T208","obj":"NCBItxid:9605"},{"id":"A209","pred":"ncbi_taxonomy_id","subj":"T209","obj":"NCBItxid:694009"},{"subj":"T205","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T206","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T207","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T208","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T209","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T210","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T211","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T212","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T213","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T214","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T196","span":{"begin":0,"end":28},"obj":"Sentence"},{"id":"T197","span":{"begin":29,"end":167},"obj":"Sentence"},{"id":"T198","span":{"begin":168,"end":249},"obj":"Sentence"},{"id":"T199","span":{"begin":250,"end":376},"obj":"Sentence"},{"id":"T200","span":{"begin":377,"end":468},"obj":"Sentence"},{"id":"T201","span":{"begin":469,"end":608},"obj":"Sentence"},{"id":"T202","span":{"begin":609,"end":776},"obj":"Sentence"},{"id":"T203","span":{"begin":777,"end":907},"obj":"Sentence"},{"id":"T204","span":{"begin":908,"end":1201},"obj":"Sentence"},{"id":"T205","span":{"begin":1202,"end":1415},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T196","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T197","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T198","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T199","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T200","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T201","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T202","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T203","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T204","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T205","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T94","span":{"begin":98,"end":106},"obj":"Disease"},{"id":"T95","span":{"begin":98,"end":102},"obj":"Disease"},{"id":"T96","span":{"begin":398,"end":402},"obj":"Disease"},{"id":"T97","span":{"begin":553,"end":557},"obj":"Disease"}],"attributes":[{"id":"A95","pred":"mondo_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A97","pred":"mondo_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A96","pred":"mondo_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A94","pred":"mondo_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T94","pred":"source","obj":"LitCovid-sample-PD-MONDO"},{"subj":"T95","pred":"source","obj":"LitCovid-sample-PD-MONDO"},{"subj":"T96","pred":"source","obj":"LitCovid-sample-PD-MONDO"},{"subj":"T97","pred":"source","obj":"LitCovid-sample-PD-MONDO"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"998","span":{"begin":79,"end":82},"obj":"Gene"},{"id":"1000","span":{"begin":83,"end":88},"obj":"Gene"},{"id":"1001","span":{"begin":98,"end":106},"obj":"Species"},{"id":"1002","span":{"begin":172,"end":180},"obj":"Species"},{"id":"999","span":{"begin":299,"end":304},"obj":"Gene"},{"id":"1003","span":{"begin":369,"end":375},"obj":"Species"},{"id":"1005","span":{"begin":398,"end":402},"obj":"Disease"},{"id":"1004","span":{"begin":408,"end":416},"obj":"Species"},{"id":"1013","span":{"begin":553,"end":557},"obj":"Disease"},{"id":"1010","span":{"begin":563,"end":571},"obj":"Species"},{"id":"1011","span":{"begin":1114,"end":1116},"obj":"Chemical"},{"id":"1012","span":{"begin":1117,"end":1119},"obj":"Chemical"}],"attributes":[{"id":"A1010","pred":"pubann:denotes","subj":"1010","obj":"Tax:1335626"},{"id":"A1001","pred":"pubann:denotes","subj":"1001","obj":"Tax:694009"},{"id":"A1013","pred":"pubann:denotes","subj":"1013","obj":"MESH:D045169"},{"id":"A999","pred":"pubann:denotes","subj":"999","obj":"Gene:43740568"},{"id":"A1003","pred":"pubann:denotes","subj":"1003","obj":"Tax:9606"},{"id":"A998","pred":"pubann:denotes","subj":"998","obj":"Gene:2995"},{"id":"A1011","pred":"pubann:denotes","subj":"1011","obj":"MESH:C022306"},{"id":"A1002","pred":"pubann:denotes","subj":"1002","obj":"Tax:1335626"},{"id":"A1005","pred":"pubann:denotes","subj":"1005","obj":"MESH:D045169"},{"id":"A1000","pred":"pubann:denotes","subj":"1000","obj":"Gene:43740568"},{"id":"A1004","pred":"pubann:denotes","subj":"1004","obj":"Tax:1335626"},{"id":"A1012","pred":"pubann:denotes","subj":"1012","obj":"MESH:D003903"},{"subj":"998","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1000","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1001","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1002","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"999","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1003","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1005","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1004","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1013","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1010","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1011","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"1012","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T6448","span":{"begin":67,"end":71},"obj":"Protein"},{"id":"T6449","span":{"begin":79,"end":82},"obj":"Protein"}],"attributes":[{"id":"A6448","pred":"uniprot_id","subj":"T6448","obj":"https://www.uniprot.org/uniprot/Q8N1N2"},{"id":"A6449","pred":"uniprot_id","subj":"T6449","obj":"https://www.uniprot.org/uniprot/P03711"},{"subj":"T6448","pred":"source","obj":"LitCovid-sample-UniProt"},{"subj":"T6449","pred":"source","obj":"LitCovid-sample-UniProt"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T196","span":{"begin":0,"end":28},"obj":"Sentence"},{"id":"T197","span":{"begin":29,"end":167},"obj":"Sentence"},{"id":"T198","span":{"begin":168,"end":249},"obj":"Sentence"},{"id":"T199","span":{"begin":250,"end":376},"obj":"Sentence"},{"id":"T200","span":{"begin":377,"end":468},"obj":"Sentence"},{"id":"T201","span":{"begin":469,"end":608},"obj":"Sentence"},{"id":"T202","span":{"begin":609,"end":776},"obj":"Sentence"},{"id":"T203","span":{"begin":777,"end":907},"obj":"Sentence"},{"id":"T204","span":{"begin":908,"end":1201},"obj":"Sentence"},{"id":"T205","span":{"begin":1202,"end":1415},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T196","pred":"source","obj":"LitCovid-sentences"},{"subj":"T197","pred":"source","obj":"LitCovid-sentences"},{"subj":"T198","pred":"source","obj":"LitCovid-sentences"},{"subj":"T199","pred":"source","obj":"LitCovid-sentences"},{"subj":"T200","pred":"source","obj":"LitCovid-sentences"},{"subj":"T201","pred":"source","obj":"LitCovid-sentences"},{"subj":"T202","pred":"source","obj":"LitCovid-sentences"},{"subj":"T203","pred":"source","obj":"LitCovid-sentences"},{"subj":"T204","pred":"source","obj":"LitCovid-sentences"},{"subj":"T205","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ecba","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#eca093"},{"id":"LitCovid-PD-MONDO","color":"#939fec"},{"id":"LitCovid-PD-CLO","color":"#b9ec93"},{"id":"LitCovid-PD-CHEBI","color":"#ec93d3"},{"id":"LitCovid-sample-PD-IDO","color":"#93eceb"},{"id":"LitCovid-sample-PD-FMA","color":"#ecd193"},{"id":"LitCovid-sample-CHEBI","color":"#b793ec"},{"id":"LitCovid-sample-PD-NCBITaxon","color":"#93ec9d"},{"id":"LitCovid-sample-sentences","color":"#ec93a3"},{"id":"LitCovid-sample-PD-MONDO","color":"#93bdec"},{"id":"LitCovid-sample-Pubtator","color":"#d7ec93"},{"id":"LitCovid-sample-UniProt","color":"#e793ec"},{"id":"LitCovid-sentences","color":"#93eccd"}]}]}}