PMC:7253482 / 27038-36048
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 854 | 52-57 | Gene | denotes | spike | Gene:43740568 |
| 855 | 40-51 | Species | denotes | coronavirus | Tax:11118 |
| 864 | 72-77 | Species | denotes | Human | Tax:9606 |
| 865 | 147-156 | Species | denotes | mammalian | Tax:9606 |
| 866 | 351-355 | Species | denotes | H3N2 | Tax:119210 |
| 867 | 512-518 | Chemical | denotes | nickel | MESH:D009532 |
| 868 | 78-94 | Disease | denotes | embryonic kidney | MESH:D007674 |
| 869 | 202-211 | Disease | denotes | SARS MERS | MESH:D018352 |
| 870 | 110-117 | CellLine | denotes | HEK293F | CVCL:6642 |
| 871 | 410-417 | CellLine | denotes | HEK293F | CVCL:6642 |
| 873 | 659-675 | Chemical | denotes | N-linked glycans | |
| 888 | 684-695 | Species | denotes | coronavirus | Tax:11118 |
| 889 | 737-749 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 890 | 754-759 | Chemical | denotes | water | MESH:D014867 |
| 891 | 839-844 | Chemical | denotes | water | MESH:D014867 |
| 892 | 914-930 | Chemical | denotes | N-linked glycans | |
| 893 | 969-981 | Chemical | denotes | procainamide | MESH:D011342 |
| 894 | 1032-1044 | Chemical | denotes | procainamide | MESH:D011342 |
| 895 | 1058-1081 | Chemical | denotes | sodium cyanoborohydrate | |
| 896 | 1089-1093 | Chemical | denotes | DMSO | MESH:D004121 |
| 897 | 1110-1121 | Chemical | denotes | acetic acid | MESH:D019342 |
| 898 | 1156-1168 | Chemical | denotes | Procainamide | MESH:D011342 |
| 899 | 1178-1185 | Chemical | denotes | glycans | MESH:D011134 |
| 900 | 1206-1212 | Chemical | denotes | Spe-ed | |
| 901 | 1213-1218 | Chemical | denotes | Amide | MESH:D000577 |
| 903 | 1253-1259 | Chemical | denotes | Glycan | MESH:D011134 |
| 910 | 1292-1299 | Chemical | denotes | glycans | MESH:D011134 |
| 911 | 1346-1356 | Chemical | denotes | BEH Glycan | |
| 912 | 1830-1842 | Chemical | denotes | oligomannose | |
| 913 | 1848-1855 | Chemical | denotes | glycans | MESH:D011134 |
| 914 | 1908-1915 | Chemical | denotes | glycans | MESH:D011134 |
| 915 | 1950-1954 | Chemical | denotes | PVDF | MESH:C024865 |
| 917 | 2073-2080 | Chemical | denotes | glycans | MESH:D011134 |
| 922 | 2172-2188 | Chemical | denotes | N-linked glycans | |
| 923 | 2267-2285 | Chemical | denotes | ammonium phosphate | MESH:C024788 |
| 924 | 2307-2316 | Chemical | denotes | phosphate | MESH:D010710 |
| 925 | 2335-2342 | Chemical | denotes | Glycans | MESH:D011134 |
| 927 | 2872-2885 | Chemical | denotes | glycopeptides | MESH:D006020 |
| 954 | 2910-2921 | Species | denotes | coronavirus | Tax:11118 |
| 955 | 3990-3993 | Species | denotes | MS2 | Tax:2710868 |
| 956 | 4064-4067 | Species | denotes | MS2 | Tax:2710868 |
| 957 | 4113-4116 | Species | denotes | MS2 | Tax:2710868 |
| 958 | 3172-3180 | Chemical | denotes | peptides | MESH:D010455 |
| 959 | 3181-3194 | Chemical | denotes | glycopeptides | MESH:D006020 |
| 960 | 3316-3327 | Chemical | denotes | formic acid | MESH:C030544 |
| 961 | 3495-3508 | Chemical | denotes | Glycopeptides | MESH:D006020 |
| 962 | 3630-3642 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 963 | 3651-3662 | Chemical | denotes | formic acid | MESH:C030544 |
| 964 | 3690-3702 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 965 | 3711-3722 | Chemical | denotes | formic acid | MESH:C030544 |
| 966 | 4255-4258 | Chemical | denotes | Glu | MESH:D018698 |
| 967 | 4356-4371 | Chemical | denotes | Carbamidomethyl | |
| 968 | 4480-4483 | Chemical | denotes | Glu | MESH:D018698 |
| 969 | 4487-4495 | Chemical | denotes | pyro-Glu | MESH:D011761 |
| 970 | 4569-4572 | Chemical | denotes | Gln | MESH:D005973 |
| 971 | 4576-4584 | Chemical | denotes | pyro-Glu | MESH:D011761 |
| 972 | 4654-4666 | Chemical | denotes | Glycopeptide | MESH:D006020 |
| 973 | 4802-4814 | Chemical | denotes | Glycopeptide | MESH:D006020 |
| 974 | 4931-4938 | Chemical | denotes | oxonium | MESH:C027727 |
| 975 | 4965-4972 | Chemical | denotes | peptide | MESH:D010455 |
| 976 | 4977-4983 | Chemical | denotes | glycan | MESH:D011134 |
| 977 | 5139-5145 | Chemical | denotes | glycan | MESH:D011134 |
| 978 | 5311-5323 | Chemical | denotes | glycopeptide | MESH:D006020 |
| 979 | 5444-5459 | Chemical | denotes | N-linked glycan | |
| 985 | 5507-5522 | Chemical | denotes | N-linked glycan | |
| 986 | 5834-5855 | Chemical | denotes | N-linked carbohydrate | |
| 987 | 5539-5543 | Disease | denotes | SARS | MESH:D045169 |
| 988 | 5545-5549 | Disease | denotes | MERS | MESH:D018352 |
| 989 | 5694-5728 | Disease | denotes | oligomannose-type N-linked glycans | MESH:C536108 |
| 998 | 5964-5967 | Gene | denotes | GPC | Gene:2995 |
| 999 | 6184-6189 | Gene | denotes | spike | Gene:43740568 |
| 1000 | 5968-5973 | Gene | denotes | spike | Gene:43740568 |
| 1001 | 5983-5991 | Species | denotes | SARS-CoV | Tax:694009 |
| 1002 | 6057-6065 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1003 | 6254-6260 | Species | denotes | humans | Tax:9606 |
| 1004 | 6293-6301 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1005 | 6283-6287 | Disease | denotes | SARS | MESH:D045169 |
| 1010 | 6448-6456 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1011 | 6999-7001 | Chemical | denotes | dN | MESH:C022306 |
| 1012 | 7002-7004 | Chemical | denotes | dS | MESH:D003903 |
| 1013 | 6438-6442 | Disease | denotes | SARS | MESH:D045169 |
| 1015 | 7487-7495 | Species | denotes | SARS-CoV | Tax:694009 |
| 1017 | 8476-8482 | Chemical | denotes | glycan | MESH:D011134 |
| 1021 | 8544-8560 | Chemical | denotes | N-linked glycans | |
| 1022 | 8705-8711 | Chemical | denotes | Glycan | MESH:D011134 |
| 1023 | 8796-8803 | Chemical | denotes | glycans | MESH:D011134 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T150 | 58-71 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T151 | 88-94 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T152 | 119-124 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T153 | 223-231 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T154 | 418-423 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T155 | 1955-1962 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T156 | 2445-2454 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T157 | 2533-2536 | Body_part | denotes | l/h | http://purl.org/sig/ont/fma/fma74642 |
| T158 | 2872-2885 | Body_part | denotes | glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T159 | 2994-3002 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T160 | 3181-3194 | Body_part | denotes | glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T161 | 3495-3508 | Body_part | denotes | Glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T162 | 3803-3812 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T163 | 4654-4666 | Body_part | denotes | Glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T164 | 4779-4786 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
| T165 | 4802-4814 | Body_part | denotes | Glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T166 | 5311-5323 | Body_part | denotes | glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T167 | 5339-5349 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T168 | 5843-5855 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T169 | 5974-5978 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T170 | 6090-6096 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T171 | 6190-6194 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T172 | 7114-7124 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T173 | 7182-7192 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T174 | 7232-7242 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T175 | 8565-8575 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T176 | 8607-8615 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T177 | 8759-8769 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T178 | 8854-8864 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T8 | 88-94 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T9 | 2445-2454 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T10 | 3224-3227 | Body_part | denotes | tip | http://purl.obolibrary.org/obo/UBERON_2001840 |
| T11 | 3803-3812 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T12 | 5856-5872 | Body_part | denotes | attachment sites | http://purl.obolibrary.org/obo/UBERON_4200047 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T94 | 202-206 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T95 | 3990-3993 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T96 | 4064-4067 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T97 | 4113-4116 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T98 | 5539-5543 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T99 | 5983-5991 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T100 | 5983-5987 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T101 | 6283-6287 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T102 | 6438-6442 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T103 | 7487-7495 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T104 | 7487-7491 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T168 | 72-77 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T169 | 78-94 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | embryonic kidney |
| T170 | 95-98 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T171 | 95-98 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T172 | 95-98 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T173 | 95-98 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T174 | 95-98 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T175 | 95-98 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T176 | 95-98 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T177 | 119-124 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T178 | 173-178 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
| T179 | 243-244 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T180 | 331-332 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T181 | 418-423 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T182 | 583-584 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T183 | 606-608 | http://purl.obolibrary.org/obo/CLO_0008426 | denotes | pg |
| T184 | 646-655 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labelling |
| T185 | 777-778 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T186 | 955-963 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labelled |
| T187 | 1003-1012 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labelling |
| T188 | 1169-1177 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labelled |
| T189 | 1283-1291 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | Labelled |
| T190 | 1320-1321 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T191 | 1400-1410 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | instrument |
| T192 | 1543-1545 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T193 | 1547-1548 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T194 | 1554-1555 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T195 | 1598-1599 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T196 | 1607-1608 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T197 | 1638-1639 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T198 | 1644-1645 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T199 | 1676-1677 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T200 | 1682-1683 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T201 | 1709-1711 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T202 | 1713-1714 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T203 | 1720-1721 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T204 | 1750-1751 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T205 | 1792-1793 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T206 | 1899-1907 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labelled |
| T207 | 1948-1949 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T208 | 1971-1979 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T209 | 2127-2129 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T210 | 2141-2143 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T211 | 2206-2207 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T212 | 2220-2228 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T213 | 2249-2250 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T214 | 2382-2383 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T215 | 2396-2406 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | instrument |
| T216 | 2674-2677 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | m/s |
| T217 | 3172-3180 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T218 | 3587-3588 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T219 | 3676-3678 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T220 | 3750-3752 | http://purl.obolibrary.org/obo/CL_0000453 | denotes | LC |
| T221 | 3972-3975 | http://purl.obolibrary.org/obo/CLO_0007875 | denotes | MS1 |
| T222 | 3972-3975 | http://purl.obolibrary.org/obo/CLO_0052410 | denotes | MS1 |
| T223 | 4050-4053 | http://purl.obolibrary.org/obo/CLO_0007875 | denotes | MS1 |
| T224 | 4050-4053 | http://purl.obolibrary.org/obo/CLO_0052410 | denotes | MS1 |
| T225 | 4070-4073 | http://purl.obolibrary.org/obo/CLO_0001435 | denotes | 5e4 |
| T226 | 4100-4103 | http://purl.obolibrary.org/obo/CLO_0007875 | denotes | MS1 |
| T227 | 4100-4103 | http://purl.obolibrary.org/obo/CLO_0052410 | denotes | MS1 |
| T228 | 4248-4249 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T229 | 4516-4523 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T230 | 4605-4612 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T231 | 4908-4909 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
| T232 | 4965-4972 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T233 | 5109-5111 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T234 | 5137-5138 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T235 | 5185-5192 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T236 | 5203-5204 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T237 | 5974-5978 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T238 | 6190-6194 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T239 | 6254-6260 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T240 | 6503-6510 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T241 | 6621-6622 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T242 | 6905-6914 | http://purl.obolibrary.org/obo/UBERON_0001353 | denotes | posterior |
| T243 | 7879-7880 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T244 | 7948-7949 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T245 | 7950-7952 | http://purl.obolibrary.org/obo/CLO_0037127 | denotes | K2 |
| T246 | 8188-8191 | http://purl.obolibrary.org/obo/CLO_0001320 | denotes | 381 |
| T247 | 8188-8191 | http://purl.obolibrary.org/obo/CLO_0001321 | denotes | 381 |
| T248 | 8227-8228 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T249 | 8279-8280 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T250 | 8565-8584 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino-acid residues |
| T251 | 8565-8584 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino-acid residues |
| T252 | 8759-8778 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino-acid residues |
| T253 | 8759-8778 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino-acid residues |
| T254 | 8854-8873 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino-acid residues |
| T255 | 8854-8873 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino-acid residues |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T257 | 58-71 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T258 | 223-231 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T259 | 256-258 | Chemical | denotes | T4 | http://purl.obolibrary.org/obo/CHEBI_18332|http://purl.obolibrary.org/obo/CHEBI_75602 |
| T261 | 512-518 | Chemical | denotes | nickel | http://purl.obolibrary.org/obo/CHEBI_28112 |
| T262 | 617-619 | Chemical | denotes | GE | http://purl.obolibrary.org/obo/CHEBI_73801 |
| T263 | 668-675 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T264 | 737-749 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T265 | 754-759 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T266 | 839-844 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T267 | 923-930 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T268 | 969-981 | Chemical | denotes | procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T269 | 1013-1020 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T270 | 1032-1044 | Chemical | denotes | procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T271 | 1058-1064 | Chemical | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708 |
| T272 | 1089-1093 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T273 | 1110-1121 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T274 | 1117-1121 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T275 | 1156-1168 | Chemical | denotes | Procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T276 | 1178-1185 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T277 | 1213-1218 | Chemical | denotes | Amide | http://purl.obolibrary.org/obo/CHEBI_32988 |
| T278 | 1253-1259 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T279 | 1292-1299 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T280 | 1350-1356 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T281 | 1742-1749 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T282 | 1762-1778 | Chemical | denotes | ammonium formate | http://purl.obolibrary.org/obo/CHEBI_63050 |
| T283 | 1762-1770 | Chemical | denotes | ammonium | http://purl.obolibrary.org/obo/CHEBI_28938 |
| T284 | 1771-1778 | Chemical | denotes | formate | http://purl.obolibrary.org/obo/CHEBI_15740|http://purl.obolibrary.org/obo/CHEBI_52343 |
| T286 | 1798-1810 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T287 | 1848-1855 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T288 | 1908-1915 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T289 | 1955-1962 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T290 | 2073-2080 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T291 | 2090-2093 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T292 | 2127-2129 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T293 | 2141-2143 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T294 | 2181-2188 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T295 | 2267-2275 | Chemical | denotes | ammonium | http://purl.obolibrary.org/obo/CHEBI_28938 |
| T296 | 2276-2285 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T300 | 2307-2316 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T304 | 2872-2885 | Chemical | denotes | glycopeptides | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T305 | 3081-3086 | Chemical | denotes | alpha | http://purl.obolibrary.org/obo/CHEBI_30216 |
| T306 | 3122-3125 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T309 | 3172-3180 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T310 | 3181-3194 | Chemical | denotes | glycopeptides | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T311 | 3316-3327 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T312 | 3323-3327 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T313 | 3604-3611 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T314 | 3630-3642 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T315 | 3651-3662 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T316 | 3658-3662 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T317 | 3690-3702 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T318 | 3711-3722 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T319 | 3718-3722 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T320 | 3750-3752 | Chemical | denotes | LC | http://purl.obolibrary.org/obo/CHEBI_73582 |
| T321 | 4225-4230 | Chemical | denotes | alpha | http://purl.obolibrary.org/obo/CHEBI_30216 |
| T322 | 4255-4258 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T325 | 4480-4483 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T328 | 4492-4495 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T331 | 4516-4523 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T332 | 4569-4572 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
| T333 | 4581-4584 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T336 | 4605-4612 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T337 | 4654-4666 | Chemical | denotes | Glycopeptide | http://purl.obolibrary.org/obo/CHEBI_141615 |
| T338 | 4779-4786 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
| T339 | 4802-4814 | Chemical | denotes | Glycopeptide | http://purl.obolibrary.org/obo/CHEBI_141615 |
| T340 | 4931-4938 | Chemical | denotes | oxonium | http://purl.obolibrary.org/obo/CHEBI_29412 |
| T341 | 4939-4943 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T342 | 4965-4972 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T343 | 5074-5078 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T344 | 5103-5107 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T345 | 5109-5111 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T346 | 5155-5157 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T347 | 5185-5192 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T348 | 5262-5265 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T349 | 5311-5323 | Chemical | denotes | glycopeptide | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T350 | 5339-5344 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T351 | 5345-5349 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T352 | 5580-5588 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T353 | 5616-5618 | Chemical | denotes | ID | http://purl.obolibrary.org/obo/CHEBI_141439 |
| T354 | 5721-5728 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T355 | 5734-5736 | Chemical | denotes | ID | http://purl.obolibrary.org/obo/CHEBI_141439 |
| T356 | 5843-5855 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T357 | 6362-6364 | Chemical | denotes | dN | http://purl.obolibrary.org/obo/CHEBI_33793 |
| T358 | 6999-7001 | Chemical | denotes | dN | http://purl.obolibrary.org/obo/CHEBI_33793 |
| T359 | 7114-7119 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T360 | 7120-7124 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T361 | 7182-7187 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T362 | 7188-7192 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T363 | 7232-7237 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T364 | 7238-7242 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T365 | 7307-7309 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T366 | 7363-7365 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T367 | 7885-7890 | Chemical | denotes | Titan | http://purl.obolibrary.org/obo/CHEBI_33341 |
| T368 | 8553-8560 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T369 | 8565-8584 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T370 | 8565-8570 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T371 | 8571-8575 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T372 | 8705-8711 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T373 | 8759-8778 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T374 | 8759-8764 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T375 | 8765-8769 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T376 | 8796-8803 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T377 | 8835-8842 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T378 | 8854-8873 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T379 | 8854-8859 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T380 | 8860-8864 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
LitCovid-sample-MedDRA
| Id | Subject | Object | Predicate | Lexical cue | meddra_id |
|---|---|---|---|---|---|
| T12 | 436-444 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | cultures | http://purl.bioontology.org/ontology/MEDDRA/10061447 |
| T13 | 5589-5599 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | microscopy | http://purl.bioontology.org/ontology/MEDDRA/10069374 |
| T14 | 8034-8042 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | weighted | http://purl.bioontology.org/ontology/MEDDRA/10047890 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T85 | 119-124 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
| T86 | 308-312 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
| T87 | 418-423 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
| T88 | 4146-4151 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | sites |
| T89 | 5460-5464 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
| T90 | 5806-5810 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
| T91 | 5867-5872 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | sites |
| T92 | 6503-6510 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T93 | 7109-7113 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
LitCovid-sample-Enju
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1486 | 0-7 | NNS | denotes | Methods |
| T1487 | 9-19 | NN | denotes | Expression |
| T1488 | 20-23 | CC | denotes | and |
| T1489 | 24-36 | NN | denotes | purification |
| T1490 | 37-39 | IN | denotes | of |
| T1491 | 40-51 | NN | denotes | coronavirus |
| T1492 | 52-57 | NN | denotes | spike |
| T1493 | 58-71 | NNS | denotes | glycoproteins |
| R1523 | T1487 | T1488 | arg1Of | Expression,and |
| R1524 | T1489 | T1488 | arg2Of | purification,and |
| R1525 | T1488 | T1490 | arg1Of | and,of |
| R1526 | T1493 | T1490 | arg2Of | glycoproteins,of |
| R1527 | T1493 | T1491 | arg1Of | glycoproteins,coronavirus |
| R1528 | T1493 | T1492 | arg1Of | glycoproteins,spike |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T149 | 58-71 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T150 | 88-94 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T151 | 119-124 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T152 | 223-231 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T153 | 418-423 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T154 | 1955-1962 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T155 | 2445-2454 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T156 | 2872-2885 | Body_part | denotes | glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T157 | 2994-3002 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T158 | 3181-3194 | Body_part | denotes | glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T159 | 3495-3508 | Body_part | denotes | Glycopeptides | http://purl.org/sig/ont/fma/fma82784 |
| T160 | 3803-3812 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T161 | 4654-4666 | Body_part | denotes | Glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T162 | 4779-4786 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
| T163 | 4802-4814 | Body_part | denotes | Glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T164 | 5311-5323 | Body_part | denotes | glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T165 | 5339-5349 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T166 | 5843-5855 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
| T167 | 5974-5978 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T168 | 6090-6096 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T169 | 6190-6194 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T170 | 7114-7124 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T171 | 7182-7192 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T172 | 7232-7242 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T173 | 8565-8575 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T174 | 8607-8615 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T175 | 8759-8769 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T176 | 8854-8864 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T174 | 58-71 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T175 | 223-231 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T176 | 512-518 | Chemical | denotes | nickel | http://purl.obolibrary.org/obo/CHEBI_28112 |
| T177 | 668-675 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T178 | 737-749 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T179 | 754-759 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T180 | 839-844 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T181 | 923-930 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T182 | 969-981 | Chemical | denotes | procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T183 | 1013-1020 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T184 | 1032-1044 | Chemical | denotes | procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T185 | 1058-1064 | Chemical | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708 |
| T186 | 1089-1093 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T187 | 1110-1121 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T188 | 1156-1168 | Chemical | denotes | Procainamide | http://purl.obolibrary.org/obo/CHEBI_8428 |
| T189 | 1178-1185 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T190 | 1213-1218 | Chemical | denotes | Amide | http://purl.obolibrary.org/obo/CHEBI_32988 |
| T191 | 1253-1259 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T192 | 1292-1299 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T193 | 1350-1356 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T194 | 1762-1778 | Chemical | denotes | ammonium formate | http://purl.obolibrary.org/obo/CHEBI_63050 |
| T195 | 1798-1810 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T196 | 1848-1855 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T197 | 1908-1915 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T198 | 1955-1962 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T199 | 2073-2080 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T200 | 2090-2093 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T201 | 2181-2188 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T202 | 2267-2275 | Chemical | denotes | ammonium | http://purl.obolibrary.org/obo/CHEBI_28938 |
| T203 | 2276-2285 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T207 | 2307-2316 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T211 | 2872-2885 | Chemical | denotes | glycopeptides | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T212 | 3122-3125 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T215 | 3172-3180 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T216 | 3181-3194 | Chemical | denotes | glycopeptides | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T217 | 3316-3327 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T218 | 3630-3642 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T219 | 3651-3662 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T220 | 3690-3702 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T221 | 3711-3722 | Chemical | denotes | formic acid | http://purl.obolibrary.org/obo/CHEBI_30751 |
| T222 | 4255-4258 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T225 | 4480-4483 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T228 | 4492-4495 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T231 | 4516-4523 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T232 | 4569-4572 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
| T233 | 4581-4584 | Chemical | denotes | Glu | http://purl.obolibrary.org/obo/CHEBI_16015|http://purl.obolibrary.org/obo/CHEBI_18237|http://purl.obolibrary.org/obo/CHEBI_29972 |
| T236 | 4605-4612 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T237 | 4654-4666 | Chemical | denotes | Glycopeptide | http://purl.obolibrary.org/obo/CHEBI_141615 |
| T238 | 4779-4786 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
| T239 | 4802-4814 | Chemical | denotes | Glycopeptide | http://purl.obolibrary.org/obo/CHEBI_141615 |
| T240 | 4931-4938 | Chemical | denotes | oxonium | http://purl.obolibrary.org/obo/CHEBI_29412 |
| T241 | 4939-4943 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T242 | 4965-4972 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T243 | 5074-5078 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T244 | 5103-5107 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T245 | 5185-5192 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T246 | 5262-5265 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T247 | 5311-5323 | Chemical | denotes | glycopeptide | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T248 | 5339-5344 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T249 | 5721-5728 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T250 | 5843-5855 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
| T251 | 7114-7119 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T252 | 7182-7187 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T253 | 7232-7237 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T254 | 7885-7890 | Chemical | denotes | Titan | http://purl.obolibrary.org/obo/CHEBI_33341 |
| T255 | 8553-8560 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T256 | 8565-8584 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T257 | 8705-8711 | Chemical | denotes | Glycan | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T258 | 8759-8778 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T259 | 8796-8803 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
| T260 | 8854-8873 | Chemical | denotes | amino-acid residues | http://purl.obolibrary.org/obo/CHEBI_33708 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T196 | 72-77 | Species | denotes | Human | NCBItxid:9606 |
| T197 | 157-162 | Species | denotes | codon | NCBItxid:79338 |
| T198 | 202-206 | Species | denotes | SARS | NCBItxid:694009 |
| T199 | 207-211 | Species | denotes | MERS | NCBItxid:1335626 |
| T200 | 351-355 | Species | denotes | H3N2 | NCBItxid:119210 |
| T201 | 356-364 | Species | denotes | Victoria | NCBItxid:4420 |
| T202 | 3475-3481 | Species | denotes | Fisher | NCBItxid:76720 |
| T203 | 5539-5543 | Species | denotes | SARS | NCBItxid:694009 |
| T204 | 5545-5549 | Species | denotes | MERS | NCBItxid:1335626 |
| T205 | 5983-5991 | Species | denotes | SARS-CoV | NCBItxid:694009 |
| T206 | 5983-5987 | Species | denotes | SARS | NCBItxid:694009 |
| T207 | 6057-6065 | Species | denotes | MERS-CoV | NCBItxid:1335626 |
| T208 | 6254-6260 | Species | denotes | humans | NCBItxid:9605 |
| T209 | 6283-6287 | Species | denotes | SARS | NCBItxid:694009 |
| T210 | 6293-6301 | Species | denotes | MERS-CoV | NCBItxid:1335626 |
| T211 | 6438-6442 | Species | denotes | SARS | NCBItxid:694009 |
| T212 | 6448-6456 | Species | denotes | MERS-CoV | NCBItxid:1335626 |
| T213 | 6503-6510 | Species | denotes | viruses | NCBItxid:10239 |
| T214 | 6623-6628 | Species | denotes | codon | NCBItxid:79338 |
| T215 | 7487-7495 | Species | denotes | SARS-CoV | NCBItxid:694009 |
| T216 | 7487-7491 | Species | denotes | SARS | NCBItxid:694009 |
| T217 | 7905-7911 | Species | denotes | Fisher | NCBItxid:76720 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T150 | 0-7 | Sentence | denotes | Methods |
| T151 | 9-71 | Sentence | denotes | Expression and purification of coronavirus spike glycoproteins |
| T152 | 72-350 | Sentence | denotes | Human embryonic kidney 293 Freestyle (HEK293F) cells were transfected with mammalian-codon-optimised genes encoding 2P-stabilised SARS MERS and HKU1 S proteins containing a C-terminal T4 fibritin trimerization domain, an HRV3C cleavage site, an 8xHis-tag and a Twin-Strep-tag41. |
| T153 | 351-424 | Sentence | denotes | H3N2 Victoria 2011 hemagglutinin was also expressed in the HEK293F cells. |
| T154 | 425-632 | Sentence | denotes | The 200 ml cultures were harvested 6 days after transfection, filtered and purified by nickel-affinity chromatography and size exclusion chromatography using a SuperdexTM 16/600 75 pg column (GE Healthcare). |
| T155 | 634-675 | Sentence | denotes | Release and labelling of N-linked glycans |
| T156 | 676-797 | Sentence | denotes | Excised coronavirus S gel bands were washed alternately with acetonitrile and water before drying in a vacuum centrifuge. |
| T157 | 798-892 | Sentence | denotes | The bands were rehydrated with 100 μL of water and incubated with PNGase F at 37 °C overnight. |
| T158 | 893-1155 | Sentence | denotes | Aliquots of released N-linked glycans were also fluorescently labelled with procainamide, by adding 100 μL of labelling mixture (110 mg/mL procainamide and 60 mg/mL sodium cyanoborohydrate in 70% DMSO and 30% glacial acetic acid) and incubating for 4 h at 65 °C. |
| T159 | 1156-1251 | Sentence | denotes | Procainamide labelled glycans were purified using Spe-ed Amide 2 columns (Applied Separations). |
| T160 | 1253-1282 | Sentence | denotes | Glycan analysis by HILIC-UPLC |
| T161 | 1283-1495 | Sentence | denotes | Labelled glycans were analysed using a 2.1 mm × 150 mm Acquity BEH Glycan column (Waters) on an Acquity H-Class UPLC instrument (Waters), with fluorescence measurements occurring at λex = 310 nm and λem = 370 nm. |
| T162 | 1496-1542 | Sentence | denotes | The following gradient was used: time (t) = 0: |
| T163 | 1543-1591 | Sentence | denotes | 22% A, 78% B (flow rate = 0.5 mL/min); t = 38.5: |
| T164 | 1592-1632 | Sentence | denotes | 44.1% A, 55.9% B (0.5 mL/min); t = 39.5: |
| T165 | 1633-1670 | Sentence | denotes | 100% A, 0% B (0.25 mL/min); t = 44.5: |
| T166 | 1671-1708 | Sentence | denotes | 100% A, 0% B (0.25 mL/min); t = 46.5: |
| T167 | 1709-1811 | Sentence | denotes | 22% A, 78% B (0.5 mL/min), where solvent A was 50 mM ammonium formate (pH 4.4) and B was acetonitrile. |
| T168 | 1812-1992 | Sentence | denotes | Quantification of oligomannose-type glycans was achieved by digestion of fluorescently labelled glycans with Endo H, and clean-up using a PVDF protein-binding membrane (Millipore). |
| T169 | 1993-2050 | Sentence | denotes | Empower 3 software (Waters) was used for data processing. |
| T170 | 2052-2080 | Sentence | denotes | Mass spectrometry of glycans |
| T171 | 2081-2334 | Sentence | denotes | Prior to ion-mobility electrospray ionisation MS and tandem MS analysis, PNGase F released N-linked glycans were purified on a Nafion® 117 membrane (Sigma-Aldrich) and a trace amount of ammonium phosphate was added to promote phosphate adduct formation. |
| T172 | 2335-2751 | Sentence | denotes | Glycans were analyzed by direct infusion using a Synapt G2Si instrument (Waters) with the following settings: capillary voltage, 0.8–1.0 kV; sample cone, 150 V; extraction cone, 150 V; cone gas, 40 l/h; source temperature, 80 °C; trap collision voltage, 4–160 V; transfer collision voltage, 4 V; trap DC bias, 60 V; IMS wave velocity, 450 m/s; IMS wave height, 40 V; trap gas flow, 2 ml/min; IMS gas flow, 80 ml/min. |
| T173 | 2752-2849 | Sentence | denotes | Data were acquired and processed with MassLynx v4.1 and Driftscope version 2.8 software (Waters). |
| T174 | 2851-2885 | Sentence | denotes | Mass spectrometry of glycopeptides |
| T175 | 2886-2993 | Sentence | denotes | Aliquots of 30–50 μg of coronavirus spikes were denatured, reduced and alkylated as described previously36. |
| T176 | 2994-3138 | Sentence | denotes | Proteins were proteolytically digested with trypsin (Promega), chymotrypsin (Promega), alpha-lytic protease (Sigma-Aldrich) and Glu-C (Promega). |
| T177 | 3139-3282 | Sentence | denotes | Reaction mixtures were dried and peptides/glycopeptides were extracted using C18 Zip-tip (MerckMilipore) following the manufacturer’s protocol. |
| T178 | 3283-3494 | Sentence | denotes | Samples were resuspended in 0.1% formic acid prior to analysis by liquid chromatography-mass spectrometry using an Easy-nLC 1200 system coupled to an Orbitrap Fusion mass spectrometer (Thermo Fisher Scientific). |
| T179 | 3495-3723 | Sentence | denotes | Glycopeptides were separated using an EasySpray PepMap RSLC C18 column (75 μm × 75 cm) with a 240-min linear solvent gradient of 0–32% acetonitrile in 0.1% formic acid, followed by 35 min of 80% acetonitrile in 0.1% formic acid. |
| T180 | 3724-3871 | Sentence | denotes | Other settings include an LC flow rate of 200 nL/min, spray voltage of 2.8 kV, capillary temperature of 275 °C, and an HCD collision energy of 50%. |
| T181 | 3872-4003 | Sentence | denotes | Precursor and fragmentation detection were performed using an Orbitrap at the following resolution: MS1 = 100,000 and MS2 = 30,000. |
| T182 | 4004-4122 | Sentence | denotes | The automatic gain control (AGC) targets were MS1 = 4e5 and MS2 = 5e4, and injection times were MS1 = 50 and MS2 = 54. |
| T183 | 4123-4265 | Sentence | denotes | The following cleavage sites were used for the respective proteases; trypsin=R/K, chymotrypsin=F/Y/W, alpha lytic protease=T/A/S/V, Glu C=E/D. |
| T184 | 4266-4307 | Sentence | denotes | Number of missed cleavages were set at 3. |
| T185 | 4308-4355 | Sentence | denotes | The following modifications were also included: |
| T186 | 4356-4653 | Sentence | denotes | Carbamidomethyl (+57.021464, target=C, fine control=fixed), Oxidation (+15.994915, target=M, fine control=variable rare 1), Glu to pyro-Glu (−18.010565, target=peptide N-term E, fine control=variable rare 1), and Gln to pyro-Glu (−17.026549, target peptide N-term Q, fine control=variable rare 1). |
| T187 | 4654-4801 | Sentence | denotes | Glycopeptide fragmentation data were extracted form raw files using ByonicTM (Version 3.5.0) and ByologicTM (Version 3.5-15; Protein Metrics Inc.). |
| T188 | 4802-5013 | Sentence | denotes | Glycopeptide fragmentation data were manually evaluated with true-positive assignments given when correct b- and y-fragments and oxonium ions corresponding to the peptide and glycan, respectively, were observed. |
| T189 | 5014-5108 | Sentence | denotes | The precursor mass tolerance was set at 4 ppm for precursor ions and 10 ppm for fragment ions. |
| T190 | 5109-5202 | Sentence | denotes | MS data were searched using a glycan library (SI Fig. 9) with the identical peptide sequence. |
| T191 | 5203-5247 | Sentence | denotes | A 1% false discovery rate (FDR) was applied. |
| T192 | 5248-5465 | Sentence | denotes | The extracted ion chromatographic areas for each true-positive glycopeptide, with the same amino-acid sequence, were compared to determine the relative quantitation of glycoforms at each specific N-linked glycan site. |
| T193 | 5467-5485 | Sentence | denotes | Model construction |
| T194 | 5486-5759 | Sentence | denotes | Structural models of N-linked glycan presentation on SARS, MERS and HKU1 S were created using electron microscopy structures (PDB ID 5X58, 5X59, and 5I08, respectively)9,11, along with complex-, hybrid-, and oligomannose-type N-linked glycans (PDB ID 4BYH, 4B7I, and 2WAH). |
| T195 | 5760-5883 | Sentence | denotes | The most dominant glycoform presented at each site was modelled on to the N-linked carbohydrate attachment sites in Coot68. |
| T196 | 5885-5913 | Sentence | denotes | Molecular evolution analysis |
| T197 | 5914-6052 | Sentence | denotes | Publicly available sequences encoding full-length GPC spike gene for SARS-CoV (3765 bp) were downloaded from GenBank and manually aligned. |
| T198 | 6053-6134 | Sentence | denotes | For MERS-CoV, we leveraged the whole genome alignment collated by Dudas et al.69. |
| T199 | 6135-6261 | Sentence | denotes | Specifically, the alignment corresponding to the spike gene was extracted (4059 bp), excluding sequences isolated from humans. |
| T200 | 6262-6353 | Sentence | denotes | Final alignments for SARS- and MERS-CoV corresponded to 70 and 100 sequences, respectively. |
| T201 | 6354-6493 | Sentence | denotes | For the dN/dS analysis, we first estimated Bayesian molecular clock phylogenies for SARS- and MERS-CoV independently using BEAST v 1.8.470. |
| T202 | 6494-6661 | Sentence | denotes | For both viruses, we assumed an uncorrelated log-normal distributed molecular clock71, Bayesian Skyline coalescent prior72 and a codon-structured substitution model73. |
| T203 | 6662-6792 | Sentence | denotes | Multiple independent MCMC runs of 10–20 million steps were executed to ensure that stationarity and convergence had been achieved. |
| T204 | 6793-7086 | Sentence | denotes | Empirical distributions of time-scaled phylogenies were obtained by combining (after the removal of burnin) the posterior tree distributions from the separate runs, which were subsequently used to estimate dN/dS ratios using the renaissance counting approach74,75 implemented in BEAST v 1.8.4. |
| T205 | 7087-7300 | Sentence | denotes | We also estimated per-site amino-acid diversity, which was calculated as the average number of amino-acid difference between two sequences at an amino-acid position in all possible pairs in the sequence alignment. |
| T206 | 7302-7341 | Sentence | denotes | Cryo-EM data analysis and visualization |
| T207 | 7342-7473 | Sentence | denotes | Single-particle cryo-EM data analysis of BG505 SOSIP.664 in complex with RM20A3 Fab was reproduced directly from Berndsen et al.51. |
| T208 | 7474-7700 | Sentence | denotes | Data for the SARS-CoV S 2P ectodomain was previously published52 and the final particle stack and alignment parameters from the published reconstruction were used for 3D variability analysis in the SPARX software package76,77. |
| T209 | 7701-7835 | Sentence | denotes | All metadata for these reconstructions along with raw data images and FSC resolution curves can be found in the original publications. |
| T210 | 7836-7993 | Sentence | denotes | In summary, both datasets were acquired on a FEI Titan Krios (Thermo Fisher) operating at 300 KeV equipped with a K2 Summit Direct Electron Detector (Gatan). |
| T211 | 7994-8106 | Sentence | denotes | Movie micrographs were aligned and dose weighted with MotionCor278 and CTF estimation was performed with Gctf79. |
| T212 | 8107-8192 | Sentence | denotes | Single-particle data processing was performed using CryoSparc v.280 and Relion v.381. |
| T213 | 8193-8278 | Sentence | denotes | Maps were low-pass filtered using a Gaussian kernel and visualized in UCSF chimera82. |
| T214 | 8279-8445 | Sentence | denotes | A detailed description of the auto-thresholding method used to set the isosurface value for visualisation of low-pass filtered maps can be found in Berndsen et al.51. |
| T215 | 8447-8490 | Sentence | denotes | Clustering analysis of viral glycan shields |
| T216 | 8491-8704 | Sentence | denotes | Solvent-accessible residues and interactions between N-linked glycans and amino-acid residues were calculated using Proteins, Interfaces, Structures and Assemblies (PISA) European Bioinformatics Institute (EBI)83. |
| T217 | 8705-8874 | Sentence | denotes | Glycan shield density was calculated by the number of amino-acid residues interacting with glycans divided by the total number of solvent-accessible amino-acid residues. |
| T218 | 8876-8893 | Sentence | denotes | Reporting summary |
| T219 | 8894-9010 | Sentence | denotes | Further information on research design is available in the Nature Research Reporting Summary linked to this article. |
LitCovid-sample-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T8 | 88-94 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T9 | 2445-2454 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T10 | 3224-3227 | Body_part | denotes | tip | http://purl.obolibrary.org/obo/UBERON_2001840 |
| T11 | 3803-3812 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T12 | 5856-5872 | Body_part | denotes | attachment sites | http://purl.obolibrary.org/obo/UBERON_4200047 |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T89 | 202-206 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T90 | 3990-3993 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T91 | 4064-4067 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T92 | 4113-4116 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
| T93 | 5539-5543 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T94 | 5983-5991 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T95 | 5983-5987 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T96 | 6283-6287 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T97 | 6438-6442 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T98 | 7487-7495 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T99 | 7487-7491 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 855 | 40-51 | Species | denotes | coronavirus | Tax:11118 |
| 854 | 52-57 | Gene | denotes | spike | Gene:43740568 |
| 864 | 72-77 | Species | denotes | Human | Tax:9606 |
| 868 | 78-94 | Disease | denotes | embryonic kidney | MESH:D007674 |
| 870 | 110-117 | CellLine | denotes | HEK293F | CVCL:6642 |
| 865 | 147-156 | Species | denotes | mammalian | Tax:9606 |
| 869 | 202-211 | Disease | denotes | SARS MERS | MESH:D018352 |
| 866 | 351-355 | Species | denotes | H3N2 | Tax:119210 |
| 871 | 410-417 | CellLine | denotes | HEK293F | CVCL:6642 |
| 867 | 512-518 | Chemical | denotes | nickel | MESH:D009532 |
| 873 | 659-675 | Chemical | denotes | N-linked glycans | |
| 888 | 684-695 | Species | denotes | coronavirus | Tax:11118 |
| 889 | 737-749 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 890 | 754-759 | Chemical | denotes | water | MESH:D014867 |
| 891 | 839-844 | Chemical | denotes | water | MESH:D014867 |
| 892 | 914-930 | Chemical | denotes | N-linked glycans | |
| 893 | 969-981 | Chemical | denotes | procainamide | MESH:D011342 |
| 894 | 1032-1044 | Chemical | denotes | procainamide | MESH:D011342 |
| 895 | 1058-1081 | Chemical | denotes | sodium cyanoborohydrate | |
| 896 | 1089-1093 | Chemical | denotes | DMSO | MESH:D004121 |
| 897 | 1110-1121 | Chemical | denotes | acetic acid | MESH:D019342 |
| 898 | 1156-1168 | Chemical | denotes | Procainamide | MESH:D011342 |
| 910 | 1178-1185 | Chemical | denotes | glycans | MESH:D011134 |
| 899 | 1178-1185 | Chemical | denotes | glycans | MESH:D011134 |
| 900 | 1206-1212 | Chemical | denotes | Spe-ed | |
| 901 | 1213-1218 | Chemical | denotes | Amide | MESH:D000577 |
| 903 | 1253-1259 | Chemical | denotes | Glycan | MESH:D011134 |
| 911 | 1346-1356 | Chemical | denotes | BEH Glycan | |
| 912 | 1830-1842 | Chemical | denotes | oligomannose | |
| 913 | 1848-1855 | Chemical | denotes | glycans | MESH:D011134 |
| 914 | 1908-1915 | Chemical | denotes | glycans | MESH:D011134 |
| 915 | 1950-1954 | Chemical | denotes | PVDF | MESH:C024865 |
| 917 | 2073-2080 | Chemical | denotes | glycans | MESH:D011134 |
| 922 | 2172-2188 | Chemical | denotes | N-linked glycans | |
| 923 | 2267-2285 | Chemical | denotes | ammonium phosphate | MESH:C024788 |
| 924 | 2307-2316 | Chemical | denotes | phosphate | MESH:D010710 |
| 925 | 2335-2342 | Chemical | denotes | Glycans | MESH:D011134 |
| 927 | 2872-2885 | Chemical | denotes | glycopeptides | MESH:D006020 |
| 954 | 2910-2921 | Species | denotes | coronavirus | Tax:11118 |
| 958 | 3172-3180 | Chemical | denotes | peptides | MESH:D010455 |
| 959 | 3181-3194 | Chemical | denotes | glycopeptides | MESH:D006020 |
| 960 | 3316-3327 | Chemical | denotes | formic acid | MESH:C030544 |
| 961 | 3495-3508 | Chemical | denotes | Glycopeptides | MESH:D006020 |
| 962 | 3630-3642 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 963 | 3651-3662 | Chemical | denotes | formic acid | MESH:C030544 |
| 964 | 3690-3702 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 965 | 3711-3722 | Chemical | denotes | formic acid | MESH:C030544 |
| 955 | 3990-3993 | Species | denotes | MS2 | Tax:2710868 |
| 956 | 4064-4067 | Species | denotes | MS2 | Tax:2710868 |
| 957 | 4113-4116 | Species | denotes | MS2 | Tax:2710868 |
| 966 | 4255-4258 | Chemical | denotes | Glu | MESH:D018698 |
| 967 | 4356-4371 | Chemical | denotes | Carbamidomethyl | |
| 968 | 4480-4483 | Chemical | denotes | Glu | MESH:D018698 |
| 969 | 4487-4495 | Chemical | denotes | pyro-Glu | MESH:D011761 |
| 970 | 4569-4572 | Chemical | denotes | Gln | MESH:D005973 |
| 971 | 4576-4584 | Chemical | denotes | pyro-Glu | MESH:D011761 |
| 972 | 4654-4666 | Chemical | denotes | Glycopeptide | MESH:D006020 |
| 973 | 4802-4814 | Chemical | denotes | Glycopeptide | MESH:D006020 |
| 974 | 4931-4938 | Chemical | denotes | oxonium | MESH:C027727 |
| 975 | 4965-4972 | Chemical | denotes | peptide | MESH:D010455 |
| 976 | 4977-4983 | Chemical | denotes | glycan | MESH:D011134 |
| 977 | 5139-5145 | Chemical | denotes | glycan | MESH:D011134 |
| 978 | 5311-5323 | Chemical | denotes | glycopeptide | MESH:D006020 |
| 979 | 5444-5459 | Chemical | denotes | N-linked glycan | |
| 985 | 5507-5522 | Chemical | denotes | N-linked glycan | |
| 987 | 5539-5543 | Disease | denotes | SARS | MESH:D045169 |
| 988 | 5545-5549 | Disease | denotes | MERS | MESH:D018352 |
| 989 | 5694-5728 | Disease | denotes | oligomannose-type N-linked glycans | MESH:C536108 |
| 986 | 5834-5855 | Chemical | denotes | N-linked carbohydrate | |
| 998 | 5964-5967 | Gene | denotes | GPC | Gene:2995 |
| 1000 | 5968-5973 | Gene | denotes | spike | Gene:43740568 |
| 1001 | 5983-5991 | Species | denotes | SARS-CoV | Tax:694009 |
| 1002 | 6057-6065 | Species | denotes | MERS-CoV | Tax:1335626 |
| 999 | 6184-6189 | Gene | denotes | spike | Gene:43740568 |
| 1003 | 6254-6260 | Species | denotes | humans | Tax:9606 |
| 1005 | 6283-6287 | Disease | denotes | SARS | MESH:D045169 |
| 1004 | 6293-6301 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1013 | 6438-6442 | Disease | denotes | SARS | MESH:D045169 |
| 1010 | 6448-6456 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1011 | 6999-7001 | Chemical | denotes | dN | MESH:C022306 |
| 1012 | 7002-7004 | Chemical | denotes | dS | MESH:D003903 |
| 1015 | 7487-7495 | Species | denotes | SARS-CoV | Tax:694009 |
| 1017 | 8476-8482 | Chemical | denotes | glycan | MESH:D011134 |
| 1021 | 8544-8560 | Chemical | denotes | N-linked glycans | |
| 1022 | 8705-8711 | Chemical | denotes | Glycan | MESH:D011134 |
| 1023 | 8796-8803 | Chemical | denotes | glycans | MESH:D011134 |
LitCovid-sample-UniProt
| Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
|---|---|---|---|---|---|
| T5247 | 52-71 | Protein | denotes | spike glycoproteins | https://www.uniprot.org/uniprot/Q9QAS2|https://www.uniprot.org/uniprot/Q9QAR5|https://www.uniprot.org/uniprot/Q9QAQ8|https://www.uniprot.org/uniprot/Q9IW04|https://www.uniprot.org/uniprot/Q9IKD1|https://www.uniprot.org/uniprot/Q990M4|https://www.uniprot.org/uniprot/Q990M3|https://www.uniprot.org/uniprot/Q990M2|https://www.uniprot.org/uniprot/Q990M1|https://www.uniprot.org/uniprot/Q91AV1|https://www.uniprot.org/uniprot/Q91A26|https://www.uniprot.org/uniprot/Q8V436|https://www.uniprot.org/uniprot/Q8JSP8|https://www.uniprot.org/uniprot/Q8BB25|https://www.uniprot.org/uniprot/Q86623|https://www.uniprot.org/uniprot/Q85088|https://www.uniprot.org/uniprot/Q85087|https://www.uniprot.org/uniprot/Q82706|https://www.uniprot.org/uniprot/Q82683|https://www.uniprot.org/uniprot/Q80BV6|https://www.uniprot.org/uniprot/Q7TFB1|https://www.uniprot.org/uniprot/Q7TFA2|https://www.uniprot.org/uniprot/Q7TA19|https://www.uniprot.org/uniprot/Q7T6T3|https://www.uniprot.org/uniprot/Q7T696|https://www.uniprot.org/uniprot/Q77NC4|https://www.uniprot.org/uniprot/Q6TNF9|https://www.uniprot.org/uniprot/Q6R1L7|https://www.uniprot.org/uniprot/Q6QU82|https://www.uniprot.org/uniprot/Q6Q1S2|https://www.uniprot.org/uniprot/Q696Q6|https://www.uniprot.org/uniprot/Q66291|https://www.uniprot.org/uniprot/Q66290|https://www.uniprot.org/uniprot/Q66199|https://www.uniprot.org/uniprot/Q66177|https://www.uniprot.org/uniprot/Q66176|https://www.uniprot.org/uniprot/Q66174|https://www.uniprot.org/uniprot/Q65984|https://www.uniprot.org/uniprot/Q5MQD0|https://www.uniprot.org/uniprot/Q5I5X9|https://www.uniprot.org/uniprot/Q5DIY0|https://www.uniprot.org/uniprot/Q5DIX9|https://www.uniprot.org/uniprot/Q5DIX8|https://www.uniprot.org/uniprot/Q5DIX7|https://www.uniprot.org/uniprot/Q52PA3|https://www.uniprot.org/uniprot/Q4ZJS1|https://www.uniprot.org/uniprot/Q4U5G0|https://www.uniprot.org/uniprot/Q3T8J0|https://www.uniprot.org/uniprot/Q3LZX1|https://www.uniprot.org/uniprot/Q3I5J5|https://www.uniprot.org/uniprot/Q14EB0|https://www.uniprot.org/uniprot/Q0ZME7|https://www.uniprot.org/uniprot/Q0Q4F2|https://www.uniprot.org/uniprot/Q0Q475|https://www.uniprot.org/uniprot/Q0Q466|https://www.uniprot.org/uniprot/Q0GNB8|https://www.uniprot.org/uniprot/Q02385|https://www.uniprot.org/uniprot/Q02167|https://www.uniprot.org/uniprot/Q01977|https://www.uniprot.org/uniprot/Q008X4|https://www.uniprot.org/uniprot/P89344|https://www.uniprot.org/uniprot/P89343|https://www.uniprot.org/uniprot/P89342|https://www.uniprot.org/uniprot/P59594|https://www.uniprot.org/uniprot/P36334|https://www.uniprot.org/uniprot/P36300|https://www.uniprot.org/uniprot/P33470|https://www.uniprot.org/uniprot/P30208|https://www.uniprot.org/uniprot/P30207|https://www.uniprot.org/uniprot/P30206|https://www.uniprot.org/uniprot/P27662|https://www.uniprot.org/uniprot/P27655|https://www.uniprot.org/uniprot/P27277|https://www.uniprot.org/uniprot/P25194|https://www.uniprot.org/uniprot/P25193|https://www.uniprot.org/uniprot/P25192|https://www.uniprot.org/uniprot/P25191|https://www.uniprot.org/uniprot/P25190|https://www.uniprot.org/uniprot/P24413|https://www.uniprot.org/uniprot/P23052|https://www.uniprot.org/uniprot/P22432|https://www.uniprot.org/uniprot/P18450|https://www.uniprot.org/uniprot/P17662|https://www.uniprot.org/uniprot/P15777|https://www.uniprot.org/uniprot/P15423|https://www.uniprot.org/uniprot/P12722|https://www.uniprot.org/uniprot/P12651|https://www.uniprot.org/uniprot/P12650|https://www.uniprot.org/uniprot/P12647|https://www.uniprot.org/uniprot/P11225|https://www.uniprot.org/uniprot/P11224|https://www.uniprot.org/uniprot/P11223|https://www.uniprot.org/uniprot/P10033|https://www.uniprot.org/uniprot/P0DTC2|https://www.uniprot.org/uniprot/P07946|https://www.uniprot.org/uniprot/P07923|https://www.uniprot.org/uniprot/P05135|https://www.uniprot.org/uniprot/P05134|https://www.uniprot.org/uniprot/O90304|https://www.uniprot.org/uniprot/O39227|https://www.uniprot.org/uniprot/K9N5Q8|https://www.uniprot.org/uniprot/A3EXG6|https://www.uniprot.org/uniprot/A3EXD0|https://www.uniprot.org/uniprot/A3EX94 |
| T5351 | 78-87 | Protein | denotes | embryonic | https://www.uniprot.org/uniprot/P02301 |
| T5352 | 221-231 | Protein | denotes | S proteins | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
| T5385 | 259-267 | Protein | denotes | fibritin | https://www.uniprot.org/uniprot/Q9T0U8|https://www.uniprot.org/uniprot/P10104|https://www.uniprot.org/uniprot/O10628 |
| T5388 | 370-383 | Protein | denotes | hemagglutinin | 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|
| T5818 | 864-870 | Protein | denotes | PNGase | https://www.uniprot.org/uniprot/Q9TW67|https://www.uniprot.org/uniprot/Q9NR70|https://www.uniprot.org/uniprot/Q9NBD6|https://www.uniprot.org/uniprot/Q9JI78|https://www.uniprot.org/uniprot/Q9CTK3|https://www.uniprot.org/uniprot/Q9BVR8|https://www.uniprot.org/uniprot/Q96IV0|https://www.uniprot.org/uniprot/Q8K113|https://www.uniprot.org/uniprot/Q6PJD8|https://www.uniprot.org/uniprot/Q5ZJM3|https://www.uniprot.org/uniprot/Q5XI55|https://www.uniprot.org/uniprot/Q5WNE3|https://www.uniprot.org/uniprot/Q59FB1|https://www.uniprot.org/uniprot/Q503I8|https://www.uniprot.org/uniprot/Q4R6F3|https://www.uniprot.org/uniprot/B4DJE9|https://www.uniprot.org/uniprot/A8X5N2 |
| T5835 | 2154-2160 | Protein | denotes | PNGase | https://www.uniprot.org/uniprot/Q9TW67|https://www.uniprot.org/uniprot/Q9NR70|https://www.uniprot.org/uniprot/Q9NBD6|https://www.uniprot.org/uniprot/Q9JI78|https://www.uniprot.org/uniprot/Q9CTK3|https://www.uniprot.org/uniprot/Q9BVR8|https://www.uniprot.org/uniprot/Q96IV0|https://www.uniprot.org/uniprot/Q8K113|https://www.uniprot.org/uniprot/Q6PJD8|https://www.uniprot.org/uniprot/Q5ZJM3|https://www.uniprot.org/uniprot/Q5XI55|https://www.uniprot.org/uniprot/Q5WNE3|https://www.uniprot.org/uniprot/Q59FB1|https://www.uniprot.org/uniprot/Q503I8|https://www.uniprot.org/uniprot/Q4R6F3|https://www.uniprot.org/uniprot/B4DJE9|https://www.uniprot.org/uniprot/A8X5N2 |
| T5852 | 2565-2569 | Protein | denotes | trap | https://www.uniprot.org/uniprot/Q9Y2M3|https://www.uniprot.org/uniprot/Q9UFF0|https://www.uniprot.org/uniprot/Q9R1R4|https://www.uniprot.org/uniprot/Q96JT1|https://www.uniprot.org/uniprot/Q8R181|https://www.uniprot.org/uniprot/Q8NHU6|https://www.uniprot.org/uniprot/Q8K1H1|https://www.uniprot.org/uniprot/Q5VV27|https://www.uniprot.org/uniprot/Q5FVD0|https://www.uniprot.org/uniprot/E7EQD4|https://www.uniprot.org/uniprot/B4DXF7|https://www.uniprot.org/uniprot/B4DG99|https://www.uniprot.org/uniprot/B2RBX3|https://www.uniprot.org/uniprot/B1AWH5|https://www.uniprot.org/uniprot/B1AWG7|https://www.uniprot.org/uniprot/A6NCI6 |
| T5868 | 2631-2635 | Protein | denotes | trap | https://www.uniprot.org/uniprot/Q9Y2M3|https://www.uniprot.org/uniprot/Q9UFF0|https://www.uniprot.org/uniprot/Q9R1R4|https://www.uniprot.org/uniprot/Q96JT1|https://www.uniprot.org/uniprot/Q8R181|https://www.uniprot.org/uniprot/Q8NHU6|https://www.uniprot.org/uniprot/Q8K1H1|https://www.uniprot.org/uniprot/Q5VV27|https://www.uniprot.org/uniprot/Q5FVD0|https://www.uniprot.org/uniprot/E7EQD4|https://www.uniprot.org/uniprot/B4DXF7|https://www.uniprot.org/uniprot/B4DG99|https://www.uniprot.org/uniprot/B2RBX3|https://www.uniprot.org/uniprot/B1AWH5|https://www.uniprot.org/uniprot/B1AWG7|https://www.uniprot.org/uniprot/A6NCI6 |
| T5884 | 2702-2706 | Protein | denotes | trap | https://www.uniprot.org/uniprot/Q9Y2M3|https://www.uniprot.org/uniprot/Q9UFF0|https://www.uniprot.org/uniprot/Q9R1R4|https://www.uniprot.org/uniprot/Q96JT1|https://www.uniprot.org/uniprot/Q8R181|https://www.uniprot.org/uniprot/Q8NHU6|https://www.uniprot.org/uniprot/Q8K1H1|https://www.uniprot.org/uniprot/Q5VV27|https://www.uniprot.org/uniprot/Q5FVD0|https://www.uniprot.org/uniprot/E7EQD4|https://www.uniprot.org/uniprot/B4DXF7|https://www.uniprot.org/uniprot/B4DG99|https://www.uniprot.org/uniprot/B2RBX3|https://www.uniprot.org/uniprot/B1AWH5|https://www.uniprot.org/uniprot/B1AWG7|https://www.uniprot.org/uniprot/A6NCI6 |
| T5900 | 3038-3045 | Protein | denotes | trypsin | https://www.uniprot.org/uniprot/P83348|https://www.uniprot.org/uniprot/P81524|https://www.uniprot.org/uniprot/P81071|https://www.uniprot.org/uniprot/P70059|https://www.uniprot.org/uniprot/P51588|https://www.uniprot.org/uniprot/P35051|https://www.uniprot.org/uniprot/P35050|https://www.uniprot.org/uniprot/P35048|https://www.uniprot.org/uniprot/P35034|https://www.uniprot.org/uniprot/P19799|https://www.uniprot.org/uniprot/P00764|https://www.uniprot.org/uniprot/P00761|https://www.uniprot.org/uniprot/O97399 |
| T5913 | 3057-3069 | Protein | denotes | chymotrypsin | https://www.uniprot.org/uniprot/P81521|https://www.uniprot.org/uniprot/P35002|https://www.uniprot.org/uniprot/O97398 |
| T5916 | 3081-3086 | Protein | denotes | alpha | https://www.uniprot.org/uniprot/Q66765|https://www.uniprot.org/uniprot/Q66764|https://www.uniprot.org/uniprot/Q2V6G9|https://www.uniprot.org/uniprot/Q155Z9|https://www.uniprot.org/uniprot/P32540|https://www.uniprot.org/uniprot/P17594|https://www.uniprot.org/uniprot/P17593|https://www.uniprot.org/uniprot/P12296|https://www.uniprot.org/uniprot/P03304|https://www.uniprot.org/uniprot/C0MHL9|https://www.uniprot.org/uniprot/B8XTP8 |
| T5927 | 3093-3101 | Protein | denotes | protease | https://www.uniprot.org/uniprot/Q9Y6I0|https://www.uniprot.org/uniprot/Q9WJC5|https://www.uniprot.org/uniprot/Q9WF19|https://www.uniprot.org/uniprot/Q9WC63|https://www.uniprot.org/uniprot/Q9WC54|https://www.uniprot.org/uniprot/Q9UKI1|https://www.uniprot.org/uniprot/Q9UKI0|https://www.uniprot.org/uniprot/Q9UKH6|https://www.uniprot.org/uniprot/Q9UKH5|https://www.uniprot.org/uniprot/P04323|https://www.uniprot.org/uniprot/P04023|https://www.uniprot.org/uniprot/P03371|https://www.uniprot.org/uniprot/P03370|https://www.uniprot.org/uniprot/P03369|https://www.uniprot.org/uniprot/P03368|https://www.uniprot.org/uniprot/P03367|https://www.uniprot.org/uniprot/P03366|https://www.uniprot.org/uniprot/P03365|https://www.uniprot.org/uniprot/P03363|https://www.uniprot.org/uniprot/P03362|https://www.uniprot.org/uniprot/P03361|https://www.uniprot.org/uniprot/P03360|https://www.uniprot.org/uniprot/P03359|https://www.uniprot.org/uniprot/P03357|https://www.uniprot.org/uniprot/P03356|https://www.uniprot.org/uniprot/P03355|https://www.uniprot.org/uniprot/P03353|https://www.uniprot.org/uniprot/P03253|https://www.uniprot.org/uniprot/P03252|https://www.uniprot.org/uniprot/P03234|https://www.uniprot.org/uniprot/O93215|https://www.uniprot.org/uniprot/O92808|https://www.uniprot.org/uniprot/O91080|https://www.uniprot.org/uniprot/O89940|https://www.uniprot.org/uniprot/O89811|https://www.uniprot.org/uniprot/O89290|https://www.uniprot.org/uniprot/O73194|https://www.uniprot.org/uniprot/O71150|https://www.uniprot.org/uniprot/O71070|https://www.uniprot.org/uniprot/O56228|https://www.uniprot.org/uniprot/O56227|https://www.uniprot.org/uniprot/O41798|https://www.uniprot.org/uniprot/O40958|https://www.uniprot.org/uniprot/O36367|https://www.uniprot.org/uniprot/O12158|https://www.uniprot.org/uniprot/O09798|https://www.uniprot.org/uniprot/O09777|https://www.uniprot.org/uniprot/D2K3N9|https://www.uniprot.org/uniprot/D2K3N8|https://www.uniprot.org/uniprot/D0UZM9|https://www.uniprot.org/uniprot/A0A0U3TYK5|https://www.uniprot.org/uniprot/A0A0A8IBU6|https://www.uniprot.org/uniprot/Q9UKH4|https://www.uniprot.org/uniprot/Q9QSR3|https://www.uniprot.org/uniprot/Q9QM72|https://www.uniprot.org/uniprot/Q9QJ30|https://www.uniprot.org/uniprot/Q9QBZ9|https://www.uniprot.org/uniprot/Q9QBZ5|https://www.uniprot.org/uniprot/Q9QBZ1|https://www.uniprot.org/uniprot/Q9QBY3|https://www.uniprot.org/uniprot/Q9Q720|https://www.uniprot.org/uniprot/Q9IZT3|https://www.uniprot.org/uniprot/Q9IZT2|https://www.uniprot.org/uniprot/Q9IRA3|https://www.uniprot.org/uniprot/Q9IIH4|https://www.uniprot.org/uniprot/Q9IDV9|https://www.uniprot.org/uniprot/Q9E6P2|https://www.uniprot.org/uniprot/Q9E6P1|https://www.uniprot.org/uniprot/Q96629|https://www.uniprot.org/uniprot/Q91QZ3|https://www.uniprot.org/uniprot/Q8JN66|https://www.uniprot.org/uniprot/Q8I7P9|https://www.uniprot.org/uniprot/Q8AII1|https://www.uniprot.org/uniprot/Q89928|https://www.uniprot.org/uniprot/Q89855|https://www.uniprot.org/uniprot/Q89703|https://www.uniprot.org/uniprot/Q89548|https://www.uniprot.org/uniprot/Q88140|https://www.uniprot.org/uniprot/Q85590|https://www.uniprot.org/uniprot/Q85571|https://www.uniprot.org/uniprot/Q85570|https://www.uniprot.org/uniprot/Q84177|https://www.uniprot.org/uniprot/Q83906|https://www.uniprot.org/uniprot/Q83417|https://www.uniprot.org/uniprot/Q82859|https://www.uniprot.org/uniprot/Q82851|https://www.uniprot.org/uniprot/Q7SVK7|https://www.uniprot.org/uniprot/Q7M6L1|https://www.uniprot.org/uniprot/Q7M6L0|https://www.uniprot.org/uniprot/Q79666|https://www.uniprot.org/uniprot/Q79582|https://www.uniprot.org/uniprot/Q77906|https://www.uniprot.org/uniprot/Q777B6|https://www.uniprot.org/uniprot/Q77373|https://www.uniprot.org/uniprot/Q76634|https://www.uniprot.org/uniprot/Q76629|https://www.uniprot.org/uniprot/Q76605|https://www.uniprot.org/uniprot/Q75002|https://www.uniprot.org/uniprot/Q74120|https://www.uniprot.org/uniprot/Q73368|https://www.uniprot.org/uniprot/Q6UDK6|https://www.uniprot.org/uniprot/Q6UDK5|https://www.uniprot.org/uniprot/Q6SW62|https://www.uniprot.org/uniprot/Q6SW61|https://www.uniprot.org/uniprot/Q6S6T7|https://www.uniprot.org/uniprot/Q6S6T6|https://www.uniprot.org/uniprot/Q69263|https://www.uniprot.org/uniprot/Q69030|https://www.uniprot.org/uniprot/Q66541|https://www.uniprot.org/uniprot/Q65ZF9|https://www.uniprot.org/uniprot/Q65652|https://www.uniprot.org/uniprot/Q65593|https://www.uniprot.org/uniprot/Q64962|https://www.uniprot.org/uniprot/Q61577|https://www.uniprot.org/uniprot/Q5TJ03|https://www.uniprot.org/uniprot/Q4U0X6|https://www.uniprot.org/uniprot/Q3KSP9|https://www.uniprot.org/uniprot/Q2Q1R2|https://www.uniprot.org/uniprot/Q2HRB6|https://www.uniprot.org/uniprot/Q2HRB5|https://www.uniprot.org/uniprot/Q27YG9|https://www.uniprot.org/uniprot/Q1HVC7|https://www.uniprot.org/uniprot/Q18LE3|https://www.uniprot.org/uniprot/Q0R5R3|https://www.uniprot.org/uniprot/Q0R5R2|https://www.uniprot.org/uniprot/Q09SZ9|https://www.uniprot.org/uniprot/Q02836|https://www.uniprot.org/uniprot/Q01002|https://www.uniprot.org/uniprot/P90341|https://www.uniprot.org/uniprot/P89449|https://www.uniprot.org/uniprot/P87563|https://www.uniprot.org/uniprot/P84454|https://www.uniprot.org/uniprot/P68986|https://www.uniprot.org/uniprot/P68985|https://www.uniprot.org/uniprot/P68984|https://www.uniprot.org/uniprot/P63131|https://www.uniprot.org/uniprot/P63129|https://www.uniprot.org/uniprot/P63128|https://www.uniprot.org/uniprot/P63127|https://www.uniprot.org/uniprot/P63125|https://www.uniprot.org/uniprot/P63124|https://www.uniprot.org/uniprot/P63123|https://www.uniprot.org/uniprot/P63122|https://www.uniprot.org/uniprot/P63121|https://www.uniprot.org/uniprot/P63120|https://www.uniprot.org/uniprot/P63119|https://www.uniprot.org/uniprot/P54817|https://www.uniprot.org/uniprot/P52369|https://www.uniprot.org/uniprot/P52351|https://www.uniprot.org/uniprot/P42672|https://www.uniprot.org/uniprot/P35990|https://www.uniprot.org/uniprot/P35963|https://www.uniprot.org/uniprot/P35956|https://www.uniprot.org/uniprot/P33459|https://www.uniprot.org/uniprot/P32542|https://www.uniprot.org/uniprot/P31822|https://www.uniprot.org/uniprot/P30202|https://www.uniprot.org/uniprot/P28936|https://www.uniprot.org/uniprot/P27980|https://www.uniprot.org/uniprot/P27973|https://www.uniprot.org/uniprot/P27528|https://www.uniprot.org/uniprot/P27502|https://www.uniprot.org/uniprot/P26810|https://www.uniprot.org/uniprot/P26809|https://www.uniprot.org/uniprot/P26808|https://www.uniprot.org/uniprot/P25059|https://www.uniprot.org/uniprot/P24740|https://www.uniprot.org/uniprot/P24433|https://www.uniprot.org/uniprot/P24107|https://www.uniprot.org/uniprot/P23984|https://www.uniprot.org/uniprot/P23427|https://www.uniprot.org/uniprot/P23426|https://www.uniprot.org/uniprot/P22382|https://www.uniprot.org/uniprot/P21414|https://www.uniprot.org/uniprot/P20892|https://www.uniprot.org/uniprot/P20876|https://www.uniprot.org/uniprot/P20875|https://www.uniprot.org/uniprot/P20825|https://www.uniprot.org/uniprot/P19561|https://www.uniprot.org/uniprot/P19560|https://www.uniprot.org/uniprot/P19505|https://www.uniprot.org/uniprot/P19202|https://www.uniprot.org/uniprot/P19199|https://www.uniprot.org/uniprot/P19151|https://www.uniprot.org/uniprot/P19119|https://www.uniprot.org/uniprot/P19028|https://www.uniprot.org/uniprot/P18802|https://www.uniprot.org/uniprot/P18096|https://www.uniprot.org/uniprot/P18042|https://www.uniprot.org/uniprot/P17965|https://www.uniprot.org/uniprot/P17757|https://www.uniprot.org/uniprot/P17283|https://www.uniprot.org/uniprot/P16901|https://www.uniprot.org/uniprot/P16753|https://www.uniprot.org/uniprot/P16423|https://www.uniprot.org/uniprot/P16088|https://www.uniprot.org/uniprot/P16046|https://www.uniprot.org/uniprot/P15833|https://www.uniprot.org/uniprot/P14078|https://www.uniprot.org/uniprot/P14074|https://www.uniprot.org/uniprot/P12502|https://www.uniprot.org/uniprot/P12499|https://www.uniprot.org/uniprot/P12498|https://www.uniprot.org/uniprot/P12497|https://www.uniprot.org/uniprot/P12451|https://www.uniprot.org/uniprot/P11826|https://www.uniprot.org/uniprot/P11825|https://www.uniprot.org/uniprot/P11365|https://www.uniprot.org/uniprot/P11283|https://www.uniprot.org/uniprot/P11227|https://www.uniprot.org/uniprot/P11204|https://www.uniprot.org/uniprot/P10394|https://www.uniprot.org/uniprot/P10381|https://www.uniprot.org/uniprot/P10274|https://www.uniprot.org/uniprot/P10273|https://www.uniprot.org/uniprot/P10272|https://www.uniprot.org/uniprot/P10271|https://www.uniprot.org/uniprot/P10270|https://www.uniprot.org/uniprot/P10265|https://www.uniprot.org/uniprot/P10210|https://www.uniprot.org/uniprot/P0DOI1|https://www.uniprot.org/uniprot/P0DOI0|https://www.uniprot.org/uniprot/P0C6F2|https://www.uniprot.org/uniprot/P0C211|https://www.uniprot.org/uniprot/P0C210|https://www.uniprot.org/uniprot/P09569|https://www.uniprot.org/uniprot/P09286|https://www.uniprot.org/uniprot/P08361|https://www.uniprot.org/uniprot/P07885|https://www.uniprot.org/uniprot/P05962|https://www.uniprot.org/uniprot/P05961|https://www.uniprot.org/uniprot/P05960|https://www.uniprot.org/uniprot/P05959|https://www.uniprot.org/uniprot/P05897|https://www.uniprot.org/uniprot/P05896|https://www.uniprot.org/uniprot/P05895|https://www.uniprot.org/uniprot/P04589|https://www.uniprot.org/uniprot/P04588|https://www.uniprot.org/uniprot/P04587|https://www.uniprot.org/uniprot/P04585|https://www.uniprot.org/uniprot/P04584|https://www.uniprot.org/uniprot/Q1HVC6|https://www.uniprot.org/uniprot/Q1A267|https://www.uniprot.org/uniprot/Q1A249 |
| T6171 | 3972-3975 | Protein | denotes | MS1 | https://www.uniprot.org/uniprot/Q8K4K7|https://www.uniprot.org/uniprot/B0BMV2 |
| T6173 | 4050-4053 | Protein | denotes | MS1 | https://www.uniprot.org/uniprot/Q8K4K7|https://www.uniprot.org/uniprot/B0BMV2 |
| T6175 | 4100-4103 | Protein | denotes | MS1 | https://www.uniprot.org/uniprot/Q8K4K7|https://www.uniprot.org/uniprot/B0BMV2 |
| T6177 | 4192-4199 | Protein | denotes | trypsin | https://www.uniprot.org/uniprot/P83348|https://www.uniprot.org/uniprot/P81524|https://www.uniprot.org/uniprot/P81071|https://www.uniprot.org/uniprot/P70059|https://www.uniprot.org/uniprot/P51588|https://www.uniprot.org/uniprot/P35051|https://www.uniprot.org/uniprot/P35050|https://www.uniprot.org/uniprot/P35048|https://www.uniprot.org/uniprot/P35034|https://www.uniprot.org/uniprot/P19799|https://www.uniprot.org/uniprot/P00764|https://www.uniprot.org/uniprot/P00761|https://www.uniprot.org/uniprot/O97399 |
| T6190 | 4205-4217 | Protein | denotes | chymotrypsin | https://www.uniprot.org/uniprot/P81521|https://www.uniprot.org/uniprot/P35002|https://www.uniprot.org/uniprot/O97398 |
| T6193 | 4225-4230 | Protein | denotes | alpha | https://www.uniprot.org/uniprot/Q66765|https://www.uniprot.org/uniprot/Q66764|https://www.uniprot.org/uniprot/Q2V6G9|https://www.uniprot.org/uniprot/Q155Z9|https://www.uniprot.org/uniprot/P32540|https://www.uniprot.org/uniprot/P17594|https://www.uniprot.org/uniprot/P17593|https://www.uniprot.org/uniprot/P12296|https://www.uniprot.org/uniprot/P03304|https://www.uniprot.org/uniprot/C0MHL9|https://www.uniprot.org/uniprot/B8XTP8 |
| T6204 | 4237-4245 | Protein | denotes | protease | https://www.uniprot.org/uniprot/Q9Y6I0|https://www.uniprot.org/uniprot/Q9WJC5|https://www.uniprot.org/uniprot/Q9WF19|https://www.uniprot.org/uniprot/Q9WC63|https://www.uniprot.org/uniprot/Q9WC54|https://www.uniprot.org/uniprot/Q9UKI1|https://www.uniprot.org/uniprot/Q9UKI0|https://www.uniprot.org/uniprot/Q9UKH6|https://www.uniprot.org/uniprot/Q9UKH5|https://www.uniprot.org/uniprot/P04323|https://www.uniprot.org/uniprot/P04023|https://www.uniprot.org/uniprot/P03371|https://www.uniprot.org/uniprot/P03370|https://www.uniprot.org/uniprot/P03369|https://www.uniprot.org/uniprot/P03368|https://www.uniprot.org/uniprot/P03367|https://www.uniprot.org/uniprot/P03366|https://www.uniprot.org/uniprot/P03365|https://www.uniprot.org/uniprot/P03363|https://www.uniprot.org/uniprot/P03362|https://www.uniprot.org/uniprot/P03361|https://www.uniprot.org/uniprot/P03360|https://www.uniprot.org/uniprot/P03359|https://www.uniprot.org/uniprot/P03357|https://www.uniprot.org/uniprot/P03356|https://www.uniprot.org/uniprot/P03355|https://www.uniprot.org/uniprot/P03353|https://www.uniprot.org/uniprot/P03253|https://www.uniprot.org/uniprot/P03252|https://www.uniprot.org/uniprot/P03234|https://www.uniprot.org/uniprot/O93215|https://www.uniprot.org/uniprot/O92808|https://www.uniprot.org/uniprot/O91080|https://www.uniprot.org/uniprot/O89940|https://www.uniprot.org/uniprot/O89811|https://www.uniprot.org/uniprot/O89290|https://www.uniprot.org/uniprot/O73194|https://www.uniprot.org/uniprot/O71150|https://www.uniprot.org/uniprot/O71070|https://www.uniprot.org/uniprot/O56228|https://www.uniprot.org/uniprot/O56227|https://www.uniprot.org/uniprot/O41798|https://www.uniprot.org/uniprot/O40958|https://www.uniprot.org/uniprot/O36367|https://www.uniprot.org/uniprot/O12158|https://www.uniprot.org/uniprot/O09798|https://www.uniprot.org/uniprot/O09777|https://www.uniprot.org/uniprot/D2K3N9|https://www.uniprot.org/uniprot/D2K3N8|https://www.uniprot.org/uniprot/D0UZM9|https://www.uniprot.org/uniprot/A0A0U3TYK5|https://www.uniprot.org/uniprot/A0A0A8IBU6|https://www.uniprot.org/uniprot/Q9UKH4|https://www.uniprot.org/uniprot/Q9QSR3|https://www.uniprot.org/uniprot/Q9QM72|https://www.uniprot.org/uniprot/Q9QJ30|https://www.uniprot.org/uniprot/Q9QBZ9|https://www.uniprot.org/uniprot/Q9QBZ5|https://www.uniprot.org/uniprot/Q9QBZ1|https://www.uniprot.org/uniprot/Q9QBY3|https://www.uniprot.org/uniprot/Q9Q720|https://www.uniprot.org/uniprot/Q9IZT3|https://www.uniprot.org/uniprot/Q9IZT2|https://www.uniprot.org/uniprot/Q9IRA3|https://www.uniprot.org/uniprot/Q9IIH4|https://www.uniprot.org/uniprot/Q9IDV9|https://www.uniprot.org/uniprot/Q9E6P2|https://www.uniprot.org/uniprot/Q9E6P1|https://www.uniprot.org/uniprot/Q96629|https://www.uniprot.org/uniprot/Q91QZ3|https://www.uniprot.org/uniprot/Q8JN66|https://www.uniprot.org/uniprot/Q8I7P9|https://www.uniprot.org/uniprot/Q8AII1|https://www.uniprot.org/uniprot/Q89928|https://www.uniprot.org/uniprot/Q89855|https://www.uniprot.org/uniprot/Q89703|https://www.uniprot.org/uniprot/Q89548|https://www.uniprot.org/uniprot/Q88140|https://www.uniprot.org/uniprot/Q85590|https://www.uniprot.org/uniprot/Q85571|https://www.uniprot.org/uniprot/Q85570|https://www.uniprot.org/uniprot/Q84177|https://www.uniprot.org/uniprot/Q83906|https://www.uniprot.org/uniprot/Q83417|https://www.uniprot.org/uniprot/Q82859|https://www.uniprot.org/uniprot/Q82851|https://www.uniprot.org/uniprot/Q7SVK7|https://www.uniprot.org/uniprot/Q7M6L1|https://www.uniprot.org/uniprot/Q7M6L0|https://www.uniprot.org/uniprot/Q79666|https://www.uniprot.org/uniprot/Q79582|https://www.uniprot.org/uniprot/Q77906|https://www.uniprot.org/uniprot/Q777B6|https://www.uniprot.org/uniprot/Q77373|https://www.uniprot.org/uniprot/Q76634|https://www.uniprot.org/uniprot/Q76629|https://www.uniprot.org/uniprot/Q76605|https://www.uniprot.org/uniprot/Q75002|https://www.uniprot.org/uniprot/Q74120|https://www.uniprot.org/uniprot/Q73368|https://www.uniprot.org/uniprot/Q6UDK6|https://www.uniprot.org/uniprot/Q6UDK5|https://www.uniprot.org/uniprot/Q6SW62|https://www.uniprot.org/uniprot/Q6SW61|https://www.uniprot.org/uniprot/Q6S6T7|https://www.uniprot.org/uniprot/Q6S6T6|https://www.uniprot.org/uniprot/Q69263|https://www.uniprot.org/uniprot/Q69030|https://www.uniprot.org/uniprot/Q66541|https://www.uniprot.org/uniprot/Q65ZF9|https://www.uniprot.org/uniprot/Q65652|https://www.uniprot.org/uniprot/Q65593|https://www.uniprot.org/uniprot/Q64962|https://www.uniprot.org/uniprot/Q61577|https://www.uniprot.org/uniprot/Q5TJ03|https://www.uniprot.org/uniprot/Q4U0X6|https://www.uniprot.org/uniprot/Q3KSP9|https://www.uniprot.org/uniprot/Q2Q1R2|https://www.uniprot.org/uniprot/Q2HRB6|https://www.uniprot.org/uniprot/Q2HRB5|https://www.uniprot.org/uniprot/Q27YG9|https://www.uniprot.org/uniprot/Q1HVC7|https://www.uniprot.org/uniprot/Q18LE3|https://www.uniprot.org/uniprot/Q0R5R3|https://www.uniprot.org/uniprot/Q0R5R2|https://www.uniprot.org/uniprot/Q09SZ9|https://www.uniprot.org/uniprot/Q02836|https://www.uniprot.org/uniprot/Q01002|https://www.uniprot.org/uniprot/P90341|https://www.uniprot.org/uniprot/P89449|https://www.uniprot.org/uniprot/P87563|https://www.uniprot.org/uniprot/P84454|https://www.uniprot.org/uniprot/P68986|https://www.uniprot.org/uniprot/P68985|https://www.uniprot.org/uniprot/P68984|https://www.uniprot.org/uniprot/P63131|https://www.uniprot.org/uniprot/P63129|https://www.uniprot.org/uniprot/P63128|https://www.uniprot.org/uniprot/P63127|https://www.uniprot.org/uniprot/P63125|https://www.uniprot.org/uniprot/P63124|https://www.uniprot.org/uniprot/P63123|https://www.uniprot.org/uniprot/P63122|https://www.uniprot.org/uniprot/P63121|https://www.uniprot.org/uniprot/P63120|https://www.uniprot.org/uniprot/P63119|https://www.uniprot.org/uniprot/P54817|https://www.uniprot.org/uniprot/P52369|https://www.uniprot.org/uniprot/P52351|https://www.uniprot.org/uniprot/P42672|https://www.uniprot.org/uniprot/P35990|https://www.uniprot.org/uniprot/P35963|https://www.uniprot.org/uniprot/P35956|https://www.uniprot.org/uniprot/P33459|https://www.uniprot.org/uniprot/P32542|https://www.uniprot.org/uniprot/P31822|https://www.uniprot.org/uniprot/P30202|https://www.uniprot.org/uniprot/P28936|https://www.uniprot.org/uniprot/P27980|https://www.uniprot.org/uniprot/P27973|https://www.uniprot.org/uniprot/P27528|https://www.uniprot.org/uniprot/P27502|https://www.uniprot.org/uniprot/P26810|https://www.uniprot.org/uniprot/P26809|https://www.uniprot.org/uniprot/P26808|https://www.uniprot.org/uniprot/P25059|https://www.uniprot.org/uniprot/P24740|https://www.uniprot.org/uniprot/P24433|https://www.uniprot.org/uniprot/P24107|https://www.uniprot.org/uniprot/P23984|https://www.uniprot.org/uniprot/P23427|https://www.uniprot.org/uniprot/P23426|https://www.uniprot.org/uniprot/P22382|https://www.uniprot.org/uniprot/P21414|https://www.uniprot.org/uniprot/P20892|https://www.uniprot.org/uniprot/P20876|https://www.uniprot.org/uniprot/P20875|https://www.uniprot.org/uniprot/P20825|https://www.uniprot.org/uniprot/P19561|https://www.uniprot.org/uniprot/P19560|https://www.uniprot.org/uniprot/P19505|https://www.uniprot.org/uniprot/P19202|https://www.uniprot.org/uniprot/P19199|https://www.uniprot.org/uniprot/P19151|https://www.uniprot.org/uniprot/P19119|https://www.uniprot.org/uniprot/P19028|https://www.uniprot.org/uniprot/P18802|https://www.uniprot.org/uniprot/P18096|https://www.uniprot.org/uniprot/P18042|https://www.uniprot.org/uniprot/P17965|https://www.uniprot.org/uniprot/P17757|https://www.uniprot.org/uniprot/P17283|https://www.uniprot.org/uniprot/P16901|https://www.uniprot.org/uniprot/P16753|https://www.uniprot.org/uniprot/P16423|https://www.uniprot.org/uniprot/P16088|https://www.uniprot.org/uniprot/P16046|https://www.uniprot.org/uniprot/P15833|https://www.uniprot.org/uniprot/P14078|https://www.uniprot.org/uniprot/P14074|https://www.uniprot.org/uniprot/P12502|https://www.uniprot.org/uniprot/P12499|https://www.uniprot.org/uniprot/P12498|https://www.uniprot.org/uniprot/P12497|https://www.uniprot.org/uniprot/P12451|https://www.uniprot.org/uniprot/P11826|https://www.uniprot.org/uniprot/P11825|https://www.uniprot.org/uniprot/P11365|https://www.uniprot.org/uniprot/P11283|https://www.uniprot.org/uniprot/P11227|https://www.uniprot.org/uniprot/P11204|https://www.uniprot.org/uniprot/P10394|https://www.uniprot.org/uniprot/P10381|https://www.uniprot.org/uniprot/P10274|https://www.uniprot.org/uniprot/P10273|https://www.uniprot.org/uniprot/P10272|https://www.uniprot.org/uniprot/P10271|https://www.uniprot.org/uniprot/P10270|https://www.uniprot.org/uniprot/P10265|https://www.uniprot.org/uniprot/P10210|https://www.uniprot.org/uniprot/P0DOI1|https://www.uniprot.org/uniprot/P0DOI0|https://www.uniprot.org/uniprot/P0C6F2|https://www.uniprot.org/uniprot/P0C211|https://www.uniprot.org/uniprot/P0C210|https://www.uniprot.org/uniprot/P09569|https://www.uniprot.org/uniprot/P09286|https://www.uniprot.org/uniprot/P08361|https://www.uniprot.org/uniprot/P07885|https://www.uniprot.org/uniprot/P05962|https://www.uniprot.org/uniprot/P05961|https://www.uniprot.org/uniprot/P05960|https://www.uniprot.org/uniprot/P05959|https://www.uniprot.org/uniprot/P05897|https://www.uniprot.org/uniprot/P05896|https://www.uniprot.org/uniprot/P05895|https://www.uniprot.org/uniprot/P04589|https://www.uniprot.org/uniprot/P04588|https://www.uniprot.org/uniprot/P04587|https://www.uniprot.org/uniprot/P04585|https://www.uniprot.org/uniprot/P04584|https://www.uniprot.org/uniprot/Q1HVC6|https://www.uniprot.org/uniprot/Q1A267|https://www.uniprot.org/uniprot/Q1A249 |
| T6448 | 5952-5956 | Protein | denotes | full | https://www.uniprot.org/uniprot/Q8N1N2 |
| T6449 | 5964-5967 | Protein | denotes | GPC | https://www.uniprot.org/uniprot/P03711 |
| T6450 | 8065-8068 | Protein | denotes | CTF | https://www.uniprot.org/uniprot/Q9Y6R8|https://www.uniprot.org/uniprot/Q9UPK1|https://www.uniprot.org/uniprot/Q9UPK0|https://www.uniprot.org/uniprot/Q9UPJ9|https://www.uniprot.org/uniprot/Q9UPJ3|https://www.uniprot.org/uniprot/Q9UPH1|https://www.uniprot.org/uniprot/Q9R1G5|https://www.uniprot.org/uniprot/Q9R1G4|https://www.uniprot.org/uniprot/Q9R1G3|https://www.uniprot.org/uniprot/Q9R1G2|https://www.uniprot.org/uniprot/Q9P2A9|https://www.uniprot.org/uniprot/Q9H3X9|https://www.uniprot.org/uniprot/Q99MA8|https://www.uniprot.org/uniprot/Q99MA7|https://www.uniprot.org/uniprot/Q99MA6|https://www.uniprot.org/uniprot/Q99MA5|https://www.uniprot.org/uniprot/Q99MA4|https://www.uniprot.org/uniprot/Q99MA3|https://www.uniprot.org/uniprot/Q99L78|https://www.uniprot.org/uniprot/Q96J45|https://www.uniprot.org/uniprot/Q90932|https://www.uniprot.org/uniprot/Q8VBT5|https://www.uniprot.org/uniprot/Q8TA97|https://www.uniprot.org/uniprot/Q6ZNF9|https://www.uniprot.org/uniprot/Q64192|https://www.uniprot.org/uniprot/Q63HM5|https://www.uniprot.org/uniprot/Q63782|https://www.uniprot.org/uniprot/Q61960|https://www.uniprot.org/uniprot/Q5VW29|https://www.uniprot.org/uniprot/Q5U094|https://www.uniprot.org/uniprot/Q54A99|https://www.uniprot.org/uniprot/Q3UUZ2|https://www.uniprot.org/uniprot/Q3U2I9|https://www.uniprot.org/uniprot/Q14938|https://www.uniprot.org/uniprot/Q14932|https://www.uniprot.org/uniprot/Q13052|https://www.uniprot.org/uniprot/Q13050|https://www.uniprot.org/uniprot/Q12859|https://www.uniprot.org/uniprot/Q12858|https://www.uniprot.org/uniprot/Q12857|https://www.uniprot.org/uniprot/Q0VG09|https://www.uniprot.org/uniprot/Q02780|https://www.uniprot.org/uniprot/P97863|https://www.uniprot.org/uniprot/P70258|https://www.uniprot.org/uniprot/P70257|https://www.uniprot.org/uniprot/P70256|https://www.uniprot.org/uniprot/P70255|https://www.uniprot.org/uniprot/P70254|https://www.uniprot.org/uniprot/P70253|https://www.uniprot.org/uniprot/P70252|https://www.uniprot.org/uniprot/P70251|https://www.uniprot.org/uniprot/P70250|https://www.uniprot.org/uniprot/P21999|https://www.uniprot.org/uniprot/P17926|https://www.uniprot.org/uniprot/P17925|https://www.uniprot.org/uniprot/P17924|https://www.uniprot.org/uniprot/P17923|https://www.uniprot.org/uniprot/P14057|https://www.uniprot.org/uniprot/P13623|https://www.uniprot.org/uniprot/P13622|https://www.uniprot.org/uniprot/P09414|https://www.uniprot.org/uniprot/P08652|https://www.uniprot.org/uniprot/P08651|https://www.uniprot.org/uniprot/O60413|https://www.uniprot.org/uniprot/O09072|https://www.uniprot.org/uniprot/O08519|https://www.uniprot.org/uniprot/O00712|https://www.uniprot.org/uniprot/O00166|https://www.uniprot.org/uniprot/K7EMU1|https://www.uniprot.org/uniprot/H7BYE8|https://www.uniprot.org/uniprot/G3V1P1|https://www.uniprot.org/uniprot/F8W8W3|https://www.uniprot.org/uniprot/F5H0R0|https://www.uniprot.org/uniprot/B7Z9C3|https://www.uniprot.org/uniprot/B7Z4U5|https://www.uniprot.org/uniprot/B4DS53|https://www.uniprot.org/uniprot/B4DRJ3|https://www.uniprot.org/uniprot/B4DM25|https://www.uniprot.org/uniprot/A8K1H0 |
LitCovid-sample-PD-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5 | 88-94 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
LitCovid-sample-PD-GO-BP-0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T57 | 864-872 | http://purl.obolibrary.org/obo/GO_0000224 | denotes | PNGase F |
| T58 | 1872-1881 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestion |
| T59 | 2154-2162 | http://purl.obolibrary.org/obo/GO_0000224 | denotes | PNGase F |
| T60 | 2324-2333 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
LitCovid-sample-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T51 | 1872-1881 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestion |
| T52 | 2324-2333 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T53 | 5208-5213 | http://purl.obolibrary.org/obo/GO_0071878 | denotes | false |
| T54 | 5208-5213 | http://purl.obolibrary.org/obo/GO_0071877 | denotes | false |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T56 | 1872-1881 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestion |
| T57 | 2324-2333 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T150 | 0-7 | Sentence | denotes | Methods |
| T151 | 9-71 | Sentence | denotes | Expression and purification of coronavirus spike glycoproteins |
| T152 | 72-350 | Sentence | denotes | Human embryonic kidney 293 Freestyle (HEK293F) cells were transfected with mammalian-codon-optimised genes encoding 2P-stabilised SARS MERS and HKU1 S proteins containing a C-terminal T4 fibritin trimerization domain, an HRV3C cleavage site, an 8xHis-tag and a Twin-Strep-tag41. |
| T153 | 351-424 | Sentence | denotes | H3N2 Victoria 2011 hemagglutinin was also expressed in the HEK293F cells. |
| T154 | 425-632 | Sentence | denotes | The 200 ml cultures were harvested 6 days after transfection, filtered and purified by nickel-affinity chromatography and size exclusion chromatography using a SuperdexTM 16/600 75 pg column (GE Healthcare). |
| T155 | 634-675 | Sentence | denotes | Release and labelling of N-linked glycans |
| T156 | 676-797 | Sentence | denotes | Excised coronavirus S gel bands were washed alternately with acetonitrile and water before drying in a vacuum centrifuge. |
| T157 | 798-892 | Sentence | denotes | The bands were rehydrated with 100 μL of water and incubated with PNGase F at 37 °C overnight. |
| T158 | 893-1155 | Sentence | denotes | Aliquots of released N-linked glycans were also fluorescently labelled with procainamide, by adding 100 μL of labelling mixture (110 mg/mL procainamide and 60 mg/mL sodium cyanoborohydrate in 70% DMSO and 30% glacial acetic acid) and incubating for 4 h at 65 °C. |
| T159 | 1156-1251 | Sentence | denotes | Procainamide labelled glycans were purified using Spe-ed Amide 2 columns (Applied Separations). |
| T160 | 1253-1282 | Sentence | denotes | Glycan analysis by HILIC-UPLC |
| T161 | 1283-1495 | Sentence | denotes | Labelled glycans were analysed using a 2.1 mm × 150 mm Acquity BEH Glycan column (Waters) on an Acquity H-Class UPLC instrument (Waters), with fluorescence measurements occurring at λex = 310 nm and λem = 370 nm. |
| T162 | 1496-1542 | Sentence | denotes | The following gradient was used: time (t) = 0: |
| T163 | 1543-1591 | Sentence | denotes | 22% A, 78% B (flow rate = 0.5 mL/min); t = 38.5: |
| T164 | 1592-1632 | Sentence | denotes | 44.1% A, 55.9% B (0.5 mL/min); t = 39.5: |
| T165 | 1633-1670 | Sentence | denotes | 100% A, 0% B (0.25 mL/min); t = 44.5: |
| T166 | 1671-1708 | Sentence | denotes | 100% A, 0% B (0.25 mL/min); t = 46.5: |
| T167 | 1709-1811 | Sentence | denotes | 22% A, 78% B (0.5 mL/min), where solvent A was 50 mM ammonium formate (pH 4.4) and B was acetonitrile. |
| T168 | 1812-1992 | Sentence | denotes | Quantification of oligomannose-type glycans was achieved by digestion of fluorescently labelled glycans with Endo H, and clean-up using a PVDF protein-binding membrane (Millipore). |
| T169 | 1993-2050 | Sentence | denotes | Empower 3 software (Waters) was used for data processing. |
| T170 | 2052-2080 | Sentence | denotes | Mass spectrometry of glycans |
| T171 | 2081-2334 | Sentence | denotes | Prior to ion-mobility electrospray ionisation MS and tandem MS analysis, PNGase F released N-linked glycans were purified on a Nafion® 117 membrane (Sigma-Aldrich) and a trace amount of ammonium phosphate was added to promote phosphate adduct formation. |
| T172 | 2335-2751 | Sentence | denotes | Glycans were analyzed by direct infusion using a Synapt G2Si instrument (Waters) with the following settings: capillary voltage, 0.8–1.0 kV; sample cone, 150 V; extraction cone, 150 V; cone gas, 40 l/h; source temperature, 80 °C; trap collision voltage, 4–160 V; transfer collision voltage, 4 V; trap DC bias, 60 V; IMS wave velocity, 450 m/s; IMS wave height, 40 V; trap gas flow, 2 ml/min; IMS gas flow, 80 ml/min. |
| T173 | 2752-2849 | Sentence | denotes | Data were acquired and processed with MassLynx v4.1 and Driftscope version 2.8 software (Waters). |
| T174 | 2851-2885 | Sentence | denotes | Mass spectrometry of glycopeptides |
| T175 | 2886-2993 | Sentence | denotes | Aliquots of 30–50 μg of coronavirus spikes were denatured, reduced and alkylated as described previously36. |
| T176 | 2994-3138 | Sentence | denotes | Proteins were proteolytically digested with trypsin (Promega), chymotrypsin (Promega), alpha-lytic protease (Sigma-Aldrich) and Glu-C (Promega). |
| T177 | 3139-3282 | Sentence | denotes | Reaction mixtures were dried and peptides/glycopeptides were extracted using C18 Zip-tip (MerckMilipore) following the manufacturer’s protocol. |
| T178 | 3283-3494 | Sentence | denotes | Samples were resuspended in 0.1% formic acid prior to analysis by liquid chromatography-mass spectrometry using an Easy-nLC 1200 system coupled to an Orbitrap Fusion mass spectrometer (Thermo Fisher Scientific). |
| T179 | 3495-3723 | Sentence | denotes | Glycopeptides were separated using an EasySpray PepMap RSLC C18 column (75 μm × 75 cm) with a 240-min linear solvent gradient of 0–32% acetonitrile in 0.1% formic acid, followed by 35 min of 80% acetonitrile in 0.1% formic acid. |
| T180 | 3724-3871 | Sentence | denotes | Other settings include an LC flow rate of 200 nL/min, spray voltage of 2.8 kV, capillary temperature of 275 °C, and an HCD collision energy of 50%. |
| T181 | 3872-4003 | Sentence | denotes | Precursor and fragmentation detection were performed using an Orbitrap at the following resolution: MS1 = 100,000 and MS2 = 30,000. |
| T182 | 4004-4122 | Sentence | denotes | The automatic gain control (AGC) targets were MS1 = 4e5 and MS2 = 5e4, and injection times were MS1 = 50 and MS2 = 54. |
| T183 | 4123-4265 | Sentence | denotes | The following cleavage sites were used for the respective proteases; trypsin=R/K, chymotrypsin=F/Y/W, alpha lytic protease=T/A/S/V, Glu C=E/D. |
| T184 | 4266-4307 | Sentence | denotes | Number of missed cleavages were set at 3. |
| T185 | 4308-4355 | Sentence | denotes | The following modifications were also included: |
| T186 | 4356-4653 | Sentence | denotes | Carbamidomethyl (+57.021464, target=C, fine control=fixed), Oxidation (+15.994915, target=M, fine control=variable rare 1), Glu to pyro-Glu (−18.010565, target=peptide N-term E, fine control=variable rare 1), and Gln to pyro-Glu (−17.026549, target peptide N-term Q, fine control=variable rare 1). |
| T187 | 4654-4801 | Sentence | denotes | Glycopeptide fragmentation data were extracted form raw files using ByonicTM (Version 3.5.0) and ByologicTM (Version 3.5-15; Protein Metrics Inc.). |
| T188 | 4802-5013 | Sentence | denotes | Glycopeptide fragmentation data were manually evaluated with true-positive assignments given when correct b- and y-fragments and oxonium ions corresponding to the peptide and glycan, respectively, were observed. |
| T189 | 5014-5108 | Sentence | denotes | The precursor mass tolerance was set at 4 ppm for precursor ions and 10 ppm for fragment ions. |
| T190 | 5109-5202 | Sentence | denotes | MS data were searched using a glycan library (SI Fig. 9) with the identical peptide sequence. |
| T191 | 5203-5247 | Sentence | denotes | A 1% false discovery rate (FDR) was applied. |
| T192 | 5248-5465 | Sentence | denotes | The extracted ion chromatographic areas for each true-positive glycopeptide, with the same amino-acid sequence, were compared to determine the relative quantitation of glycoforms at each specific N-linked glycan site. |
| T193 | 5467-5485 | Sentence | denotes | Model construction |
| T194 | 5486-5759 | Sentence | denotes | Structural models of N-linked glycan presentation on SARS, MERS and HKU1 S were created using electron microscopy structures (PDB ID 5X58, 5X59, and 5I08, respectively)9,11, along with complex-, hybrid-, and oligomannose-type N-linked glycans (PDB ID 4BYH, 4B7I, and 2WAH). |
| T195 | 5760-5883 | Sentence | denotes | The most dominant glycoform presented at each site was modelled on to the N-linked carbohydrate attachment sites in Coot68. |
| T196 | 5885-5913 | Sentence | denotes | Molecular evolution analysis |
| T197 | 5914-6052 | Sentence | denotes | Publicly available sequences encoding full-length GPC spike gene for SARS-CoV (3765 bp) were downloaded from GenBank and manually aligned. |
| T198 | 6053-6134 | Sentence | denotes | For MERS-CoV, we leveraged the whole genome alignment collated by Dudas et al.69. |
| T199 | 6135-6261 | Sentence | denotes | Specifically, the alignment corresponding to the spike gene was extracted (4059 bp), excluding sequences isolated from humans. |
| T200 | 6262-6353 | Sentence | denotes | Final alignments for SARS- and MERS-CoV corresponded to 70 and 100 sequences, respectively. |
| T201 | 6354-6493 | Sentence | denotes | For the dN/dS analysis, we first estimated Bayesian molecular clock phylogenies for SARS- and MERS-CoV independently using BEAST v 1.8.470. |
| T202 | 6494-6661 | Sentence | denotes | For both viruses, we assumed an uncorrelated log-normal distributed molecular clock71, Bayesian Skyline coalescent prior72 and a codon-structured substitution model73. |
| T203 | 6662-6792 | Sentence | denotes | Multiple independent MCMC runs of 10–20 million steps were executed to ensure that stationarity and convergence had been achieved. |
| T204 | 6793-7086 | Sentence | denotes | Empirical distributions of time-scaled phylogenies were obtained by combining (after the removal of burnin) the posterior tree distributions from the separate runs, which were subsequently used to estimate dN/dS ratios using the renaissance counting approach74,75 implemented in BEAST v 1.8.4. |
| T205 | 7087-7300 | Sentence | denotes | We also estimated per-site amino-acid diversity, which was calculated as the average number of amino-acid difference between two sequences at an amino-acid position in all possible pairs in the sequence alignment. |
| T206 | 7302-7341 | Sentence | denotes | Cryo-EM data analysis and visualization |
| T207 | 7342-7473 | Sentence | denotes | Single-particle cryo-EM data analysis of BG505 SOSIP.664 in complex with RM20A3 Fab was reproduced directly from Berndsen et al.51. |
| T208 | 7474-7700 | Sentence | denotes | Data for the SARS-CoV S 2P ectodomain was previously published52 and the final particle stack and alignment parameters from the published reconstruction were used for 3D variability analysis in the SPARX software package76,77. |
| T209 | 7701-7835 | Sentence | denotes | All metadata for these reconstructions along with raw data images and FSC resolution curves can be found in the original publications. |
| T210 | 7836-7993 | Sentence | denotes | In summary, both datasets were acquired on a FEI Titan Krios (Thermo Fisher) operating at 300 KeV equipped with a K2 Summit Direct Electron Detector (Gatan). |
| T211 | 7994-8106 | Sentence | denotes | Movie micrographs were aligned and dose weighted with MotionCor278 and CTF estimation was performed with Gctf79. |
| T212 | 8107-8192 | Sentence | denotes | Single-particle data processing was performed using CryoSparc v.280 and Relion v.381. |
| T213 | 8193-8278 | Sentence | denotes | Maps were low-pass filtered using a Gaussian kernel and visualized in UCSF chimera82. |
| T214 | 8279-8445 | Sentence | denotes | A detailed description of the auto-thresholding method used to set the isosurface value for visualisation of low-pass filtered maps can be found in Berndsen et al.51. |
| T215 | 8447-8490 | Sentence | denotes | Clustering analysis of viral glycan shields |
| T216 | 8491-8704 | Sentence | denotes | Solvent-accessible residues and interactions between N-linked glycans and amino-acid residues were calculated using Proteins, Interfaces, Structures and Assemblies (PISA) European Bioinformatics Institute (EBI)83. |
| T217 | 8705-8874 | Sentence | denotes | Glycan shield density was calculated by the number of amino-acid residues interacting with glycans divided by the total number of solvent-accessible amino-acid residues. |
| T218 | 8876-8893 | Sentence | denotes | Reporting summary |
| T219 | 8894-9010 | Sentence | denotes | Further information on research design is available in the Nature Research Reporting Summary linked to this article. |
LitCovid-sample-Glycan
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T50 | 7701-7704 | https://glytoucan.org/Structures/Glycans/G05518TD | denotes | All |