PMC:7253482 / 19836-20451 JSONTXT

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{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T72","span":{"begin":39,"end":43},"obj":"Disease"},{"id":"T73","span":{"begin":145,"end":149},"obj":"Disease"}],"attributes":[{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

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{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T202","span":{"begin":24,"end":26},"obj":"Chemical"},{"id":"T203","span":{"begin":135,"end":137},"obj":"Chemical"},{"id":"T204","span":{"begin":342,"end":344},"obj":"Chemical"},{"id":"T205","span":{"begin":356,"end":368},"obj":"Chemical"},{"id":"T206","span":{"begin":426,"end":433},"obj":"Chemical"},{"id":"T207","span":{"begin":594,"end":598},"obj":"Chemical"}],"attributes":[{"id":"A202","pred":"chebi_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/CHEBI_73507"},{"id":"A203","pred":"chebi_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/CHEBI_73507"},{"id":"A204","pred":"chebi_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/CHEBI_73507"},{"id":"A205","pred":"chebi_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A206","pred":"chebi_id","subj":"T206","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A207","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_22695"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T54","span":{"begin":208,"end":218},"obj":"http://purl.obolibrary.org/obo/OGMS_0000045"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

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5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T109","span":{"begin":50,"end":53},"obj":"Body_part"},{"id":"T110","span":{"begin":138,"end":141},"obj":"Body_part"},{"id":"T111","span":{"begin":345,"end":348},"obj":"Body_part"},{"id":"T112","span":{"begin":356,"end":368},"obj":"Body_part"},{"id":"T113","span":{"begin":439,"end":442},"obj":"Body_part"},{"id":"T114","span":{"begin":519,"end":522},"obj":"Body_part"}],"attributes":[{"id":"A109","pred":"fma_id","subj":"T109","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma67847"},{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma67847"},{"id":"A112","pred":"fma_id","subj":"T112","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A113","pred":"fma_id","subj":"T113","obj":"http://purl.org/sig/ont/fma/fma67847"},{"id":"A114","pred":"fma_id","subj":"T114","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T140","span":{"begin":356,"end":368},"obj":"Chemical"},{"id":"T141","span":{"begin":426,"end":433},"obj":"Chemical"}],"attributes":[{"id":"A140","pred":"chebi_id","subj":"T140","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A141","pred":"chebi_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T146","span":{"begin":39,"end":43},"obj":"Species"},{"id":"T147","span":{"begin":50,"end":55},"obj":"Species"},{"id":"T148","span":{"begin":145,"end":149},"obj":"Species"},{"id":"T149","span":{"begin":519,"end":524},"obj":"Species"}],"attributes":[{"id":"A146","pred":"ncbi_taxonomy_id","subj":"T146","obj":"NCBItxid:694009"},{"id":"A147","pred":"ncbi_taxonomy_id","subj":"T147","obj":"NCBItxid:11676"},{"id":"A148","pred":"ncbi_taxonomy_id","subj":"T148","obj":"NCBItxid:694009"},{"id":"A149","pred":"ncbi_taxonomy_id","subj":"T149","obj":"NCBItxid:11676"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T113","span":{"begin":0,"end":75},"obj":"Sentence"},{"id":"T114","span":{"begin":76,"end":89},"obj":"Sentence"},{"id":"T115","span":{"begin":90,"end":298},"obj":"Sentence"},{"id":"T116","span":{"begin":299,"end":312},"obj":"Sentence"},{"id":"T117","span":{"begin":313,"end":452},"obj":"Sentence"},{"id":"T118","span":{"begin":453,"end":615},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T67","span":{"begin":39,"end":43},"obj":"Disease"},{"id":"T68","span":{"begin":145,"end":149},"obj":"Disease"}],"attributes":[{"id":"A67","pred":"mondo_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A68","pred":"mondo_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"611","span":{"begin":39,"end":43},"obj":"Disease"},{"id":"609","span":{"begin":50,"end":55},"obj":"Species"},{"id":"608","span":{"begin":56,"end":59},"obj":"Gene"},{"id":"610","span":{"begin":60,"end":66},"obj":"Chemical"},{"id":"617","span":{"begin":145,"end":149},"obj":"Disease"},{"id":"616","span":{"begin":519,"end":524},"obj":"Species"},{"id":"615","span":{"begin":525,"end":528},"obj":"Gene"}],"attributes":[{"id":"A611","pred":"pubann:denotes","subj":"611","obj":"MESH:D045169"},{"id":"A609","pred":"pubann:denotes","subj":"609","obj":"Tax:11676"},{"id":"A608","pred":"pubann:denotes","subj":"608","obj":"Gene:64006"},{"id":"A610","pred":"pubann:denotes","subj":"610","obj":"MESH:D011134"},{"id":"A617","pred":"pubann:denotes","subj":"617","obj":"MESH:D045169"},{"id":"A616","pred":"pubann:denotes","subj":"616","obj":"Tax:11676"},{"id":"A615","pred":"pubann:denotes","subj":"615","obj":"Gene:64006"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T3964","span":{"begin":56,"end":59},"obj":"Protein"},{"id":"T3966","span":{"begin":356,"end":368},"obj":"Protein"},{"id":"T4051","span":{"begin":525,"end":528},"obj":"Protein"}],"attributes":[{"id":"A3964","pred":"uniprot_id","subj":"T3964","obj":"https://www.uniprot.org/uniprot/C1JJY3"},{"id":"A3965","pred":"uniprot_id","subj":"T3964","obj":"https://www.uniprot.org/uniprot/P24123"},{"id":"A3966","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q9QSP1"},{"id":"A3967","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q9QJT6"},{"id":"A3968","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q9JGT4"},{"id":"A3969","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q9IPJ6"},{"id":"A3970","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q9DIC6"},{"id":"A3971","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q91DS0"},{"id":"A3972","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q91C28"},{"id":"A3973","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8QQA2"},{"id":"A3974","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8QPE5"},{"id":"A3975","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8QPE4"},{"id":"A3976","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8QPE3"},{"id":"A3977","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8JTH0"},{"id":"A3978","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8BDV6"},{"id":"A3979","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8B6J6"},{"id":"A3980","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8B0I1"},{"id":"A3981","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8B0H6"},{"id":"A3982","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q8B0H1"},{"id":"A3983","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q89669"},{"id":"A3984","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q85213"},{"id":"A3985","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q82706"},{"id":"A3986","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q82683"},{"id":"A3987","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q82020"},{"id":"A3988","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q787B5"},{"id":"A3989","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q77SK0"},{"id":"A3990","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q77N36"},{"id":"A3991","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q76G52"},{"id":"A3992","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q75T09"},{"id":"A3993","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q6X1D5"},{"id":"A3994","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q6X1D1"},{"id":"A3995","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q6TYA0"},{"id":"A3996","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q6E0W7"},{"id":"A3997","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q66T62"},{"id":"A3998","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5VKP3"},{"id":"A3999","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5VKN9"},{"id":"A4000","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5K2K4"},{"id":"A4001","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX93"},{"id":"A4002","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX92"},{"id":"A4003","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX91"},{"id":"A4004","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX90"},{"id":"A4005","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX89"},{"id":"A4006","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX88"},{"id":"A4007","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5IX87"},{"id":"A4008","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q5GA86"},{"id":"A4009","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q58FH1"},{"id":"A4010","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q4VKV3"},{"id":"A4011","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q4F900"},{"id":"A4012","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49LL3"},{"id":"A4013","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49IU2"},{"id":"A4014","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49IU1"},{"id":"A4015","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49IT9"},{"id":"A4016","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49IT8"},{"id":"A4017","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q49AV0"},{"id":"A4018","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q0GBY1"},{"id":"A4019","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q0GBX6"},{"id":"A4020","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/Q08089"},{"id":"A4021","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P32595"},{"id":"A4022","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P32550"},{"id":"A4023","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P19462"},{"id":"A4024","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P16288"},{"id":"A4025","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P15199"},{"id":"A4026","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P13180"},{"id":"A4027","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P0C572"},{"id":"A4028","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P08667"},{"id":"A4029","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P08163"},{"id":"A4030","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P07923"},{"id":"A4031","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P04884"},{"id":"A4032","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P04883"},{"id":"A4033","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P04882"},{"id":"A4034","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P03524"},{"id":"A4035","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/P03522"},{"id":"A4036","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/O92284"},{"id":"A4037","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/O56677"},{"id":"A4038","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/O10236"},{"id":"A4039","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/J7HBH4"},{"id":"A4040","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/D8V075"},{"id":"A4041","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A7WNB3"},{"id":"A4042","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A4UHQ6"},{"id":"A4043","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A4UHQ1"},{"id":"A4044","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3RM22"},{"id":"A4045","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5R8"},{"id":"A4046","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5R3"},{"id":"A4047","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5Q8"},{"id":"A4048","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5N3"},{"id":"A4049","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5M3"},{"id":"A4050","pred":"uniprot_id","subj":"T3966","obj":"https://www.uniprot.org/uniprot/A3F5L8"},{"id":"A4051","pred":"uniprot_id","subj":"T4051","obj":"https://www.uniprot.org/uniprot/C1JJY3"},{"id":"A4052","pred":"uniprot_id","subj":"T4051","obj":"https://www.uniprot.org/uniprot/P24123"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}

{"project":"LitCovid-sentences","denotations":[{"id":"T113","span":{"begin":0,"end":75},"obj":"Sentence"},{"id":"T114","span":{"begin":76,"end":89},"obj":"Sentence"},{"id":"T115","span":{"begin":90,"end":298},"obj":"Sentence"},{"id":"T116","span":{"begin":299,"end":312},"obj":"Sentence"},{"id":"T117","span":{"begin":313,"end":452},"obj":"Sentence"},{"id":"T118","span":{"begin":453,"end":615},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fig. 5 Comparative cryo-EM analysis of SARS S and HIV-1 Env glycan shields.\na Left panel: Sharpened 3.2-Å-resolution C3-symmetric cryo-EM map of SARS S 2P ectodomain52 visualized at a high contour level with disordered S1 receptor-binding and N-terminal domains extending out from the central core. Middle panel: Low-pass filtered (lpf) cryo-EM map of the glycoprotein visualised at a low contour level along with a simulated peptide-only map overlaid. Right panel: SPARX 3D variability map51. b Same as in (a) but for HIV-1 Env BG505 SOSIP.664 construct in complex with three copies of RM20A3 base-specific Fabs51."}