PMC:7253482 / 15283-15590 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"558","span":{"begin":195,"end":197},"obj":"Chemical"},{"id":"559","span":{"begin":198,"end":200},"obj":"Chemical"},{"id":"560","span":{"begin":271,"end":273},"obj":"Chemical"},{"id":"561","span":{"begin":274,"end":276},"obj":"Chemical"}],"attributes":[{"id":"A558","pred":"tao:has_database_id","subj":"558","obj":"MESH:C022306"},{"id":"A559","pred":"tao:has_database_id","subj":"559","obj":"MESH:D003903"},{"id":"A560","pred":"tao:has_database_id","subj":"560","obj":"MESH:C022306"},{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"MESH:D003903"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T92","span":{"begin":16,"end":21},"obj":"Body_part"},{"id":"T93","span":{"begin":164,"end":174},"obj":"Body_part"}],"attributes":[{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma60992"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma82740"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T4","span":{"begin":16,"end":21},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0002488"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T176","span":{"begin":164,"end":174},"obj":"Chemical"},{"id":"T177","span":{"begin":195,"end":197},"obj":"Chemical"},{"id":"T178","span":{"begin":271,"end":273},"obj":"Chemical"}],"attributes":[{"id":"A176","pred":"chebi_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"},{"id":"A177","pred":"chebi_id","subj":"T177","obj":"http://purl.obolibrary.org/obo/CHEBI_33793"},{"id":"A178","pred":"chebi_id","subj":"T178","obj":"http://purl.obolibrary.org/obo/CHEBI_33793"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T41","span":{"begin":67,"end":77},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T42","span":{"begin":139,"end":149},"obj":"http://www.geneontology.org/formats/oboInOwl#Synonym"},{"id":"T43","span":{"begin":153,"end":163},"obj":"http://www.geneontology.org/formats/oboInOwl#Synonym"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

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pred":"arg1Of","subj":"T12652","obj":"T92287"},{"id":"R70296","pred":"arg2Of","subj":"T59603","obj":"T92287"},{"id":"R97765","pred":"arg1Of","subj":"T11718","obj":"T88501"},{"id":"R56320","pred":"arg1Of","subj":"T59603","obj":"T11718"},{"id":"R34279","pred":"arg1Of","subj":"T59603","obj":"T86795"},{"id":"R13531","pred":"arg1Of","subj":"T59603","obj":"T7211"},{"id":"R2422","pred":"arg2Of","subj":"T4769","obj":"T7211"},{"id":"R45689","pred":"arg3Of","subj":"T47239","obj":"T7211"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T91","span":{"begin":16,"end":21},"obj":"Body_part"},{"id":"T92","span":{"begin":164,"end":174},"obj":"Body_part"}],"attributes":[{"id":"A91","pred":"fma_id","subj":"T91","obj":"http://purl.org/sig/ont/fma/fma60992"},{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma82740"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T128","span":{"begin":164,"end":174},"obj":"Chemical"}],"attributes":[{"id":"A128","pred":"chebi_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T90","span":{"begin":101,"end":294},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T4","span":{"begin":16,"end":21},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0002488"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"558","span":{"begin":195,"end":197},"obj":"Chemical"},{"id":"559","span":{"begin":198,"end":200},"obj":"Chemical"},{"id":"560","span":{"begin":271,"end":273},"obj":"Chemical"},{"id":"561","span":{"begin":274,"end":276},"obj":"Chemical"}],"attributes":[{"id":"A558","pred":"pubann:denotes","subj":"558","obj":"MESH:C022306"},{"id":"A559","pred":"pubann:denotes","subj":"559","obj":"MESH:D003903"},{"id":"A560","pred":"pubann:denotes","subj":"560","obj":"MESH:C022306"},{"id":"A561","pred":"pubann:denotes","subj":"561","obj":"MESH:D003903"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}

{"project":"LitCovid-sentences","denotations":[{"id":"T90","span":{"begin":101,"end":294},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a).\nAnalysis of the relative ratio of non-synonymous to synonymous nucleotide substitutions (i.e. dN/dS ratios) revealed that exposed residues exhibited significantly higher dN/dS values (Fig. 4b). Buried resid"}