PMC:7253482 / 12499-13215 JSONTXT

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{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T107","span":{"begin":398,"end":403},"obj":"Chemical"},{"id":"T108","span":{"begin":511,"end":519},"obj":"Chemical"},{"id":"T109","span":{"begin":588,"end":593},"obj":"Chemical"},{"id":"T110","span":{"begin":676,"end":683},"obj":"Chemical"}],"attributes":[{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T86","span":{"begin":26,"end":30},"obj":"Species"},{"id":"T87","span":{"begin":35,"end":39},"obj":"Species"},{"id":"T88","span":{"begin":184,"end":188},"obj":"Species"},{"id":"T89","span":{"begin":193,"end":197},"obj":"Species"},{"id":"T90","span":{"begin":220,"end":224},"obj":"Species"},{"id":"T91","span":{"begin":229,"end":233},"obj":"Species"},{"id":"T92","span":{"begin":453,"end":457},"obj":"Species"},{"id":"T93","span":{"begin":462,"end":466},"obj":"Species"}],"attributes":[{"id":"A86","pred":"ncbi_taxonomy_id","subj":"T86","obj":"NCBItxid:694009"},{"id":"A90","pred":"ncbi_taxonomy_id","subj":"T90","obj":"NCBItxid:694009"},{"id":"A89","pred":"ncbi_taxonomy_id","subj":"T89","obj":"NCBItxid:1335626"},{"id":"A91","pred":"ncbi_taxonomy_id","subj":"T91","obj":"NCBItxid:1335626"},{"id":"A88","pred":"ncbi_taxonomy_id","subj":"T88","obj":"NCBItxid:694009"},{"id":"A87","pred":"ncbi_taxonomy_id","subj":"T87","obj":"NCBItxid:1335626"},{"id":"A92","pred":"ncbi_taxonomy_id","subj":"T92","obj":"NCBItxid:694009"},{"id":"A93","pred":"ncbi_taxonomy_id","subj":"T93","obj":"NCBItxid:1335626"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T76","span":{"begin":0,"end":57},"obj":"Sentence"},{"id":"T77","span":{"begin":58,"end":249},"obj":"Sentence"},{"id":"T78","span":{"begin":250,"end":508},"obj":"Sentence"},{"id":"T79","span":{"begin":509,"end":609},"obj":"Sentence"},{"id":"T80","span":{"begin":610,"end":716},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T42","span":{"begin":26,"end":30},"obj":"Disease"},{"id":"T43","span":{"begin":184,"end":188},"obj":"Disease"},{"id":"T44","span":{"begin":220,"end":224},"obj":"Disease"},{"id":"T45","span":{"begin":453,"end":457},"obj":"Disease"}],"attributes":[{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"410","span":{"begin":26,"end":30},"obj":"Disease"},{"id":"411","span":{"begin":35,"end":39},"obj":"Disease"},{"id":"412","span":{"begin":184,"end":188},"obj":"Disease"},{"id":"413","span":{"begin":193,"end":197},"obj":"Disease"},{"id":"414","span":{"begin":220,"end":224},"obj":"Disease"},{"id":"415","span":{"begin":229,"end":233},"obj":"Disease"},{"id":"407","span":{"begin":355,"end":357},"obj":"Chemical"},{"id":"408","span":{"begin":358,"end":360},"obj":"Chemical"},{"id":"416","span":{"begin":453,"end":457},"obj":"Disease"},{"id":"417","span":{"begin":462,"end":466},"obj":"Disease"},{"id":"409","span":{"begin":667,"end":683},"obj":"Chemical"}],"attributes":[{"id":"A407","pred":"pubann:denotes","subj":"407","obj":"MESH:C022306"},{"id":"A417","pred":"pubann:denotes","subj":"417","obj":"MESH:D018352"},{"id":"A408","pred":"pubann:denotes","subj":"408","obj":"MESH:D003903"},{"id":"A415","pred":"pubann:denotes","subj":"415","obj":"MESH:D018352"},{"id":"A411","pred":"pubann:denotes","subj":"411","obj":"MESH:D018352"},{"id":"A410","pred":"pubann:denotes","subj":"410","obj":"MESH:D045169"},{"id":"A412","pred":"pubann:denotes","subj":"412","obj":"MESH:D045169"},{"id":"A416","pred":"pubann:denotes","subj":"416","obj":"MESH:D045169"},{"id":"A414","pred":"pubann:denotes","subj":"414","obj":"MESH:D045169"},{"id":"A413","pred":"pubann:denotes","subj":"413","obj":"MESH:D018352"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T3603","span":{"begin":509,"end":519},"obj":"Protein"}],"attributes":[{"id":"A3603","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UIP0"},{"id":"A3604","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UIN9"},{"id":"A3605","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UIN8"},{"id":"A3606","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UIN7"},{"id":"A3607","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UIN6"},{"id":"A3608","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9UBH8"},{"id":"A3609","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NRH8"},{"id":"A3610","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NRH7"},{"id":"A3611","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NRH6"},{"id":"A3612","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NRH5"},{"id":"A3613","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NRH4"},{"id":"A3614","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NPG5"},{"id":"A3615","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NPE0"},{"id":"A3616","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q9NP52"},{"id":"A3617","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q95IF9"},{"id":"A3618","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q8N5P3"},{"id":"A3619","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q8IZU6"},{"id":"A3620","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q8IZU5"},{"id":"A3621","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q8IZU4"},{"id":"A3622","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q86Z04"},{"id":"A3623","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q7YR44"},{"id":"A3624","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q7LA71"},{"id":"A3625","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q7LA70"},{"id":"A3626","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q5STD2"},{"id":"A3627","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q5SQ85"},{"id":"A3628","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q1XI16"},{"id":"A3629","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q1XI12"},{"id":"A3630","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/Q15517"},{"id":"A3631","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/O43509"},{"id":"A3632","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/O19084"},{"id":"A3633","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/B0UYZ7"},{"id":"A3634","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/B0S7V2"},{"id":"A3635","pred":"uniprot_id","subj":"T3603","obj":"https://www.uniprot.org/uniprot/A5A6L9"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}

{"project":"LitCovid-sentences","denotations":[{"id":"T76","span":{"begin":0,"end":57},"obj":"Sentence"},{"id":"T77","span":{"begin":58,"end":249},"obj":"Sentence"},{"id":"T78","span":{"begin":250,"end":508},"obj":"Sentence"},{"id":"T79","span":{"begin":509,"end":609},"obj":"Sentence"},{"id":"T80","span":{"begin":610,"end":716},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"a Amino-acid diversity in SARS and MERS S gene sequences. Averaged values for each domain are also shown below. b Comparison of dN/dS values between buried and exposed residues across SARS and MERS S (n = 70 and 100 for SARS and MERS, respectively). The error bars correspond to the 95% highest posterior density intervals while the circles indicate mean dN/dS values. c Mapping of the per residue amino-acid diversity shown in A onto the structures of SARS and MERS S (PDB ID 5X58 and 5X59, respectively)11. S proteins are presented as backbone traces with residues colored according to amino-acid diversity. Residues with elevated diversity are colored in red, and N-linked glycans are presented as white surfaces."}