PMC:7253235 / 14948-23075
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 508 | 0-6 | Disease | denotes | Cancer | MESH:D009369 |
| 509 | 11-19 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 542 | 27-35 | Species | denotes | patients | Tax:9606 |
| 543 | 305-313 | Species | denotes | patients | Tax:9606 |
| 544 | 373-381 | Species | denotes | patients | Tax:9606 |
| 545 | 457-465 | Species | denotes | patients | Tax:9606 |
| 546 | 651-659 | Species | denotes | patients | Tax:9606 |
| 547 | 718-726 | Species | denotes | patients | Tax:9606 |
| 548 | 779-787 | Species | denotes | patients | Tax:9606 |
| 549 | 816-824 | Species | denotes | patients | Tax:9606 |
| 550 | 927-935 | Species | denotes | patients | Tax:9606 |
| 551 | 973-981 | Species | denotes | patients | Tax:9606 |
| 552 | 1258-1266 | Species | denotes | patients | Tax:9606 |
| 553 | 1302-1310 | Species | denotes | patients | Tax:9606 |
| 554 | 1709-1717 | Species | denotes | patients | Tax:9606 |
| 555 | 20-26 | Disease | denotes | Cancer | MESH:D009369 |
| 556 | 153-163 | Disease | denotes | malignancy | MESH:D009369 |
| 557 | 298-304 | Disease | denotes | cancer | MESH:D009369 |
| 558 | 364-372 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 559 | 450-456 | Disease | denotes | cancer | MESH:D009369 |
| 560 | 531-537 | Disease | denotes | cancer | MESH:D009369 |
| 561 | 644-650 | Disease | denotes | cancer | MESH:D009369 |
| 562 | 792-798 | Disease | denotes | cancer | MESH:D009369 |
| 563 | 918-926 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 564 | 987-993 | Disease | denotes | cancer | MESH:D009369 |
| 565 | 995-1006 | Disease | denotes | lung cancer | MESH:D008175 |
| 566 | 1040-1050 | Disease | denotes | malignancy | MESH:D009369 |
| 567 | 1089-1095 | Disease | denotes | cancer | MESH:D009369 |
| 568 | 1187-1192 | Disease | denotes | death | MESH:D003643 |
| 569 | 1251-1257 | Disease | denotes | cancer | MESH:D009369 |
| 570 | 1295-1301 | Disease | denotes | cancer | MESH:D009369 |
| 571 | 1693-1699 | Disease | denotes | cancer | MESH:D009369 |
| 572 | 1741-1752 | Disease | denotes | lung cancer | MESH:D008175 |
| 573 | 1766-1772 | Disease | denotes | cancer | MESH:D009369 |
| 593 | 3904-3912 | Species | denotes | patients | Tax:9606 |
| 594 | 4014-4022 | Species | denotes | patients | Tax:9606 |
| 595 | 4088-4101 | Species | denotes | Not specified | Tax:32644 |
| 596 | 4193-4206 | Species | denotes | Not specified | Tax:32644 |
| 597 | 4299-4312 | Species | denotes | Not specified | Tax:32644 |
| 598 | 4393-4406 | Species | denotes | Not specified | Tax:32644 |
| 599 | 4586-4599 | Species | denotes | Not specified | Tax:32644 |
| 600 | 4600-4613 | Species | denotes | Not specified | Tax:32644 |
| 601 | 4643-4656 | Species | denotes | Not specified | Tax:32644 |
| 602 | 4657-4670 | Species | denotes | Not specified | Tax:32644 |
| 603 | 4798-4811 | Species | denotes | Not specified | Tax:32644 |
| 604 | 4918-4931 | Species | denotes | Not specified | Tax:32644 |
| 605 | 5027-5040 | Species | denotes | Not specified | Tax:32644 |
| 606 | 5139-5152 | Species | denotes | Not specified | Tax:32644 |
| 607 | 3927-3935 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 608 | 3961-3967 | Disease | denotes | cancer | MESH:D009369 |
| 609 | 3994-4003 | Disease | denotes | Mortality | MESH:D003643 |
| 610 | 4007-4013 | Disease | denotes | cancer | MESH:D009369 |
| 611 | 4716-4720 | Disease | denotes | died | MESH:D003643 |
| 615 | 3725-3733 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 616 | 3747-3753 | Disease | denotes | cancer | MESH:D009369 |
| 617 | 3758-3780 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 623 | 5230-5236 | Disease | denotes | cancer | MESH:D009369 |
| 624 | 5238-5243 | Disease | denotes | tumor | MESH:D009369 |
| 625 | 5245-5263 | Disease | denotes | malignant neoplasm | MESH:D009369 |
| 626 | 5268-5277 | Disease | denotes | carcinoma | MESH:D009369 |
| 627 | 5312-5318 | Disease | denotes | cancer | MESH:D009369 |
| 632 | 5391-5413 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 633 | 5448-5462 | Disease | denotes | cardiomyopathy | MESH:D009202 |
| 634 | 5464-5487 | Disease | denotes | coronary artery disease | MESH:D003324 |
| 635 | 5493-5515 | Disease | denotes | ischemic heart disease | MESH:D003324 |
| 638 | 5593-5601 | Species | denotes | patients | Tax:9606 |
| 639 | 5687-5695 | Species | denotes | patients | Tax:9606 |
| 642 | 5713-5725 | Disease | denotes | hypertension | MESH:D006973 |
| 643 | 5727-5753 | Disease | denotes | CVD cardiovascular disease | MESH:D002318 |
| 688 | 1870-1878 | Species | denotes | patients | Tax:9606 |
| 689 | 1952-1960 | Species | denotes | patients | Tax:9606 |
| 690 | 2057-2065 | Species | denotes | patients | Tax:9606 |
| 691 | 2280-2288 | Species | denotes | patients | Tax:9606 |
| 692 | 2376-2384 | Species | denotes | patients | Tax:9606 |
| 693 | 2482-2490 | Species | denotes | patients | Tax:9606 |
| 694 | 2581-2589 | Species | denotes | patients | Tax:9606 |
| 695 | 2798-2806 | Species | denotes | patients | Tax:9606 |
| 696 | 2943-2951 | Species | denotes | patients | Tax:9606 |
| 697 | 3181-3189 | Species | denotes | patients | Tax:9606 |
| 698 | 3707-3715 | Species | denotes | patients | Tax:9606 |
| 699 | 1863-1869 | Disease | denotes | cancer | MESH:D009369 |
| 700 | 1945-1951 | Disease | denotes | cancer | MESH:D009369 |
| 701 | 1973-1982 | Disease | denotes | infection | MESH:D007239 |
| 702 | 2027-2036 | Disease | denotes | infection | MESH:D007239 |
| 703 | 2095-2120 | Disease | denotes | small cell lung carcinoma | MESH:D055752 |
| 704 | 2122-2127 | Disease | denotes | NSCLC | MESH:D002289 |
| 705 | 2212-2221 | Disease | denotes | mortality | MESH:D003643 |
| 706 | 2274-2279 | Disease | denotes | NSCLC | MESH:D002289 |
| 707 | 2345-2353 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 708 | 2390-2395 | Disease | denotes | NSCLC | MESH:D002289 |
| 709 | 2475-2481 | Disease | denotes | cancer | MESH:D009369 |
| 710 | 2525-2536 | Disease | denotes | Lung cancer | MESH:D008175 |
| 711 | 2557-2563 | Disease | denotes | cancer | MESH:D009369 |
| 712 | 2597-2605 | Disease | denotes | Diabetes | MESH:D003920 |
| 713 | 2626-2668 | Disease | denotes | cardiovascular and cerebrovascular disease | MESH:D002318 |
| 714 | 2874-2879 | Disease | denotes | tumor | MESH:D009369 |
| 715 | 2957-2963 | Disease | denotes | cancer | MESH:D009369 |
| 716 | 2987-2995 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 717 | 3026-3032 | Disease | denotes | cancer | MESH:D009369 |
| 718 | 3079-3090 | Disease | denotes | Lung cancer | MESH:D008175 |
| 719 | 3174-3180 | Disease | denotes | cancer | MESH:D009369 |
| 720 | 3250-3260 | Disease | denotes | malignancy | MESH:D009369 |
| 721 | 3301-3309 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 722 | 3310-3320 | Disease | denotes | infections | MESH:D007239 |
| 723 | 3358-3364 | Disease | denotes | cancer | MESH:D009369 |
| 724 | 3440-3446 | Disease | denotes | cancer | MESH:D009369 |
| 725 | 3500-3508 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 726 | 3509-3518 | Disease | denotes | infection | MESH:D007239 |
| 727 | 3532-3541 | Disease | denotes | infection | MESH:D007239 |
| 728 | 3550-3559 | Disease | denotes | mortality | MESH:D003643 |
| 729 | 3676-3682 | Disease | denotes | cancer | MESH:D009369 |
| 730 | 3689-3697 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 731 | 3698-3706 | Disease | denotes | infected | MESH:D007239 |
| 759 | 6668-6672 | Gene | denotes | HER2 | Gene:2064 |
| 760 | 5844-5852 | Species | denotes | patients | Tax:9606 |
| 761 | 5886-5894 | Species | denotes | patients | Tax:9606 |
| 762 | 5906-5914 | Species | denotes | patients | Tax:9606 |
| 763 | 6203-6211 | Species | denotes | patients | Tax:9606 |
| 764 | 6470-6478 | Species | denotes | patients | Tax:9606 |
| 765 | 6566-6574 | Species | denotes | patients | Tax:9606 |
| 766 | 6784-6792 | Species | denotes | patients | Tax:9606 |
| 767 | 6905-6913 | Species | denotes | patients | Tax:9606 |
| 768 | 6678-6691 | Chemical | denotes | anthracycline | MESH:D018943 |
| 769 | 5816-5824 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 770 | 5882-5885 | Disease | denotes | CVD | MESH:D002318 |
| 771 | 5899-5905 | Disease | denotes | cancer | MESH:D009369 |
| 772 | 5945-5959 | Disease | denotes | cardiac injury | MESH:D006331 |
| 773 | 6010-6019 | Disease | denotes | mortality | MESH:D003643 |
| 774 | 6069-6072 | Disease | denotes | CVD | MESH:D002318 |
| 775 | 6077-6083 | Disease | denotes | cancer | MESH:D009369 |
| 776 | 6307-6313 | Disease | denotes | cancer | MESH:D009369 |
| 777 | 6359-6371 | Disease | denotes | hypertension | MESH:D006973 |
| 778 | 6376-6398 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 779 | 6461-6469 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 780 | 6550-6565 | Disease | denotes | renal carcinoma | MESH:C538614 |
| 781 | 6587-6599 | Disease | denotes | hypertension | MESH:D006973 |
| 782 | 6643-6657 | Disease | denotes | cardiomyopathy | MESH:D009202 |
| 783 | 6703-6716 | Disease | denotes | breast cancer | MESH:D001943 |
| 784 | 6755-6777 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 785 | 6927-6935 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 801 | 7051-7059 | Species | denotes | patients | Tax:9606 |
| 802 | 7189-7197 | Species | denotes | patients | Tax:9606 |
| 803 | 7241-7249 | Species | denotes | patients | Tax:9606 |
| 804 | 7355-7363 | Species | denotes | patients | Tax:9606 |
| 805 | 7679-7687 | Species | denotes | patients | Tax:9606 |
| 806 | 8066-8074 | Species | denotes | patients | Tax:9606 |
| 807 | 7044-7050 | Disease | denotes | cancer | MESH:D009369 |
| 808 | 7076-7084 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 809 | 7157-7163 | Disease | denotes | cancer | MESH:D009369 |
| 810 | 7298-7312 | Disease | denotes | cardiotoxicity | MESH:D066126 |
| 811 | 7468-7476 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 812 | 7477-7487 | Disease | denotes | infections | MESH:D007239 |
| 813 | 7582-7603 | Disease | denotes | aggressive malignancy | MESH:D009369 |
| 814 | 7955-7961 | Disease | denotes | Cancer | MESH:D009369 |
| 815 | 7983-7989 | Disease | denotes | Cancer | MESH:D009369 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T26 | 264-269 | Body_part | denotes | Joint | http://purl.org/sig/ont/fma/fma7490 |
| T27 | 995-999 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T28 | 1741-1745 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T29 | 2101-2105 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T30 | 2106-2110 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T31 | 2525-2529 | Body_part | denotes | Lung | http://purl.org/sig/ont/fma/fma7195 |
| T32 | 3079-3083 | Body_part | denotes | Lung | http://purl.org/sig/ont/fma/fma7195 |
| T33 | 4511-4515 | Body_part | denotes | Lung | http://purl.org/sig/ont/fma/fma7195 |
| T34 | 5464-5479 | Body_part | denotes | coronary artery | http://purl.org/sig/ont/fma/fma49893 |
| T35 | 5502-5507 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T36 | 6615-6623 | Body_part | denotes | tyrosine | http://purl.org/sig/ont/fma/fma82768 |
| T37 | 6703-6709 | Body_part | denotes | breast | http://purl.org/sig/ont/fma/fma9601 |
| T38 | 7060-7064 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
| T39 | 7714-7723 | Body_part | denotes | stem cell | http://purl.org/sig/ont/fma/fma63368 |
| T40 | 7719-7723 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T19 | 995-999 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T20 | 1741-1745 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T21 | 2106-2110 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T22 | 2525-2529 | Body_part | denotes | Lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T23 | 3079-3083 | Body_part | denotes | Lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T24 | 4511-4515 | Body_part | denotes | Lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T25 | 5464-5479 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T26 | 5473-5479 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/UBERON_0001637 |
| T27 | 5502-5507 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T28 | 6703-6709 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
| T29 | 7060-7064 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T153 | 0-6 | Disease | denotes | Cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T154 | 11-19 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T155 | 20-26 | Disease | denotes | Cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T156 | 298-304 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T157 | 364-372 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T158 | 450-456 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T159 | 531-537 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T160 | 644-650 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T161 | 792-798 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T162 | 918-926 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T163 | 987-993 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T164 | 995-1006 | Disease | denotes | lung cancer | http://purl.obolibrary.org/obo/MONDO_0008903 |
| T165 | 1000-1006 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T166 | 1089-1095 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T167 | 1251-1257 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T168 | 1295-1301 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T169 | 1693-1699 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T170 | 1741-1752 | Disease | denotes | lung cancer | http://purl.obolibrary.org/obo/MONDO_0008903 |
| T171 | 1746-1752 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T172 | 1766-1772 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T173 | 1863-1869 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T174 | 1945-1951 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T175 | 1973-1982 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T176 | 2027-2036 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T177 | 2091-2120 | Disease | denotes | non-small cell lung carcinoma | http://purl.obolibrary.org/obo/MONDO_0005233 |
| T178 | 2095-2120 | Disease | denotes | small cell lung carcinoma | http://purl.obolibrary.org/obo/MONDO_0008433 |
| T179 | 2106-2120 | Disease | denotes | lung carcinoma | http://purl.obolibrary.org/obo/MONDO_0005138 |
| T180 | 2111-2120 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T181 | 2122-2127 | Disease | denotes | NSCLC | http://purl.obolibrary.org/obo/MONDO_0005233 |
| T182 | 2274-2279 | Disease | denotes | NSCLC | http://purl.obolibrary.org/obo/MONDO_0005233 |
| T183 | 2345-2353 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T184 | 2390-2395 | Disease | denotes | NSCLC | http://purl.obolibrary.org/obo/MONDO_0005233 |
| T185 | 2475-2481 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T186 | 2525-2536 | Disease | denotes | Lung cancer | http://purl.obolibrary.org/obo/MONDO_0008903 |
| T187 | 2530-2536 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T188 | 2557-2563 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T189 | 2597-2605 | Disease | denotes | Diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T190 | 2645-2668 | Disease | denotes | cerebrovascular disease | http://purl.obolibrary.org/obo/MONDO_0011057 |
| T191 | 2874-2879 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T192 | 2957-2963 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T193 | 2987-2995 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T194 | 3026-3032 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T195 | 3079-3090 | Disease | denotes | Lung cancer | http://purl.obolibrary.org/obo/MONDO_0008903 |
| T196 | 3084-3090 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T197 | 3174-3180 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T198 | 3301-3309 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T199 | 3310-3320 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T200 | 3358-3364 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T201 | 3440-3446 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T202 | 3500-3508 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T203 | 3509-3518 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T204 | 3532-3541 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T205 | 3676-3682 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T206 | 3689-3697 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T207 | 3725-3733 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T208 | 3747-3753 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T209 | 3758-3780 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T210 | 3927-3935 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T211 | 3961-3967 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T212 | 3974-3977 | Disease | denotes | HTN | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T213 | 4007-4013 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T214 | 5230-5236 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T215 | 5238-5243 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T216 | 5245-5263 | Disease | denotes | malignant neoplasm | http://purl.obolibrary.org/obo/MONDO_0004992|http://purl.obolibrary.org/obo/MONDO_0006517 |
| T218 | 5255-5263 | Disease | denotes | neoplasm | http://purl.obolibrary.org/obo/MONDO_0005070|http://purl.obolibrary.org/obo/MONDO_0021079 |
| T220 | 5268-5277 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T221 | 5312-5318 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T222 | 5391-5413 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T223 | 5448-5462 | Disease | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/MONDO_0004994 |
| T224 | 5464-5487 | Disease | denotes | coronary artery disease | http://purl.obolibrary.org/obo/MONDO_0005010 |
| T225 | 5473-5487 | Disease | denotes | artery disease | http://purl.obolibrary.org/obo/MONDO_0000473 |
| T226 | 5493-5515 | Disease | denotes | ischemic heart disease | http://purl.obolibrary.org/obo/MONDO_0024644 |
| T227 | 5502-5515 | Disease | denotes | heart disease | http://purl.obolibrary.org/obo/MONDO_0005267 |
| T228 | 5709-5712 | Disease | denotes | HTN | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T229 | 5713-5725 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T230 | 5731-5753 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T231 | 5816-5824 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T232 | 5899-5905 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T233 | 5953-5959 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T234 | 6077-6083 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T235 | 6307-6313 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T236 | 6359-6398 | Disease | denotes | hypertension and cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0001302 |
| T237 | 6359-6371 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T238 | 6376-6398 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T239 | 6461-6469 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T240 | 6550-6565 | Disease | denotes | renal carcinoma | http://purl.obolibrary.org/obo/MONDO_0005206 |
| T241 | 6556-6565 | Disease | denotes | carcinoma | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T242 | 6587-6599 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T243 | 6643-6657 | Disease | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/MONDO_0004994 |
| T244 | 6703-6716 | Disease | denotes | breast cancer | http://purl.obolibrary.org/obo/MONDO_0007254 |
| T245 | 6710-6716 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T246 | 6755-6777 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T247 | 6927-6935 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T248 | 7044-7050 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T249 | 7076-7084 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T250 | 7157-7163 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T251 | 7468-7476 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T252 | 7477-7487 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T253 | 7955-7961 | Disease | denotes | Cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T254 | 7983-7989 | Disease | denotes | Cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T94 | 88-93 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T95 | 252-255 | http://purl.obolibrary.org/obo/CLO_0008190 | denotes | Per |
| T96 | 264-269 | http://purl.obolibrary.org/obo/UBERON_0000982 | denotes | Joint |
| T97 | 264-269 | http://purl.obolibrary.org/obo/UBERON_0004905 | denotes | Joint |
| T98 | 492-494 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T99 | 701-702 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T100 | 873-874 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T101 | 913-917 | http://purl.obolibrary.org/obo/CLO_0053133 | denotes | 1590 |
| T102 | 970-972 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T103 | 995-999 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T104 | 995-999 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T105 | 1116-1117 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T106 | 1324-1325 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T107 | 1383-1384 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T108 | 1519-1521 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T109 | 1741-1745 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T110 | 1741-1745 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T111 | 1795-1796 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T112 | 1965-1966 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T113 | 2043-2044 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T114 | 2101-2105 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T115 | 2106-2110 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T116 | 2106-2110 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T117 | 2323-2324 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T118 | 2446-2447 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T119 | 2525-2529 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
| T120 | 2525-2529 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | Lung |
| T121 | 3079-3083 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
| T122 | 3079-3083 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | Lung |
| T123 | 3091-3094 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T124 | 3582-3583 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T125 | 3809-3811 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T126 | 4174-4176 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T127 | 4498-4502 | http://purl.obolibrary.org/obo/CLO_0053133 | denotes | 1590 |
| T128 | 4503-4505 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T129 | 4511-4515 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
| T130 | 4511-4515 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | Lung |
| T131 | 4518-4524 | http://purl.obolibrary.org/obo/CLO_0001409 | denotes | 5 (28) |
| T132 | 4899-4901 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T133 | 5118-5120 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T134 | 5171-5173 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T135 | 5323-5329 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T136 | 5473-5479 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| T137 | 5473-5479 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | artery |
| T138 | 5502-5507 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T139 | 5502-5507 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T140 | 5502-5507 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T141 | 5502-5507 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T142 | 5854-5855 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T143 | 5862-5865 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T144 | 6129-6134 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T145 | 6505-6506 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T146 | 6703-6709 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| T147 | 6718-6720 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T148 | 7060-7064 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
| T149 | 7426-7428 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T150 | 7664-7666 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T151 | 7714-7723 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cell |
| T152 | 7816-7817 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T24 | 1545-1550 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T25 | 1700-1705 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T26 | 2789-2794 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T27 | 4133-4136 | Chemical | denotes | Guo | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T28 | 5766-5772 | Chemical | denotes | formal | http://purl.obolibrary.org/obo/CHEBI_48341 |
| T29 | 6615-6623 | Chemical | denotes | tyrosine | http://purl.obolibrary.org/obo/CHEBI_18186 |
| T30 | 6678-6691 | Chemical | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120 |
| T31 | 7268-7272 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T32 | 7705-7710 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T33 | 8110-8114 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T90 | 0-6 | Phenotype | denotes | Cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T91 | 20-26 | Phenotype | denotes | Cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T92 | 112-132 | Phenotype | denotes | immune dysregulation | http://purl.obolibrary.org/obo/HP_0002958 |
| T93 | 298-304 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T94 | 450-456 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T95 | 531-537 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T96 | 644-650 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T97 | 792-798 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T98 | 987-993 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T99 | 995-1006 | Phenotype | denotes | lung cancer | http://purl.obolibrary.org/obo/HP_0100526 |
| T100 | 1089-1095 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T101 | 1251-1257 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T102 | 1295-1301 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T103 | 1693-1699 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T104 | 1741-1752 | Phenotype | denotes | lung cancer | http://purl.obolibrary.org/obo/HP_0100526 |
| T105 | 1766-1772 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T106 | 1863-1869 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T107 | 1945-1951 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T108 | 2091-2120 | Phenotype | denotes | non-small cell lung carcinoma | http://purl.obolibrary.org/obo/HP_0030358 |
| T109 | 2122-2127 | Phenotype | denotes | NSCLC | http://purl.obolibrary.org/obo/HP_0030358 |
| T110 | 2274-2279 | Phenotype | denotes | NSCLC | http://purl.obolibrary.org/obo/HP_0030358 |
| T111 | 2390-2395 | Phenotype | denotes | NSCLC | http://purl.obolibrary.org/obo/HP_0030358 |
| T112 | 2475-2481 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T113 | 2525-2536 | Phenotype | denotes | Lung cancer | http://purl.obolibrary.org/obo/HP_0100526 |
| T114 | 2557-2563 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T115 | 2874-2879 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |
| T116 | 2957-2963 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T117 | 3026-3032 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T118 | 3079-3090 | Phenotype | denotes | Lung cancer | http://purl.obolibrary.org/obo/HP_0100526 |
| T119 | 3174-3180 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T120 | 3358-3364 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T121 | 3440-3446 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T122 | 3676-3682 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T123 | 3747-3753 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T124 | 3758-3780 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T125 | 3961-3967 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T126 | 4007-4013 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T127 | 5230-5236 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T128 | 5238-5243 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |
| T129 | 5255-5263 | Phenotype | denotes | neoplasm | http://purl.obolibrary.org/obo/HP_0002664 |
| T130 | 5268-5277 | Phenotype | denotes | carcinoma | http://purl.obolibrary.org/obo/HP_0030731 |
| T131 | 5312-5318 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T132 | 5391-5413 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T133 | 5448-5462 | Phenotype | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/HP_0001638 |
| T134 | 5713-5725 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T135 | 5731-5753 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T136 | 5835-5843 | Phenotype | denotes | oncology | http://purl.obolibrary.org/obo/HP_0002664 |
| T137 | 5899-5905 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T138 | 6077-6083 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T139 | 6307-6313 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T140 | 6359-6371 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T141 | 6376-6398 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T142 | 6550-6565 | Phenotype | denotes | renal carcinoma | http://purl.obolibrary.org/obo/HP_0005584 |
| T143 | 6587-6599 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T144 | 6643-6657 | Phenotype | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/HP_0001638 |
| T145 | 6703-6716 | Phenotype | denotes | breast cancer | http://purl.obolibrary.org/obo/HP_0003002 |
| T146 | 6755-6777 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T147 | 7044-7050 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T148 | 7157-7163 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T149 | 7955-7961 | Phenotype | denotes | Cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T150 | 7983-7989 | Phenotype | denotes | Cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T151 | 8057-8065 | Phenotype | denotes | oncology | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T90 | 0-19 | Sentence | denotes | Cancer and COVID-19 |
| T91 | 20-251 | Sentence | denotes | Cancer patients have shown to be at higher risk for contracting the virus likely from their immune dysregulation in setting of their malignancy and various treatments and remain at high risk for sustaining severe outcomes [19, 42]. |
| T92 | 252-397 | Sentence | denotes | Per the WHO Joint Mission Report, the CFR for cancer patients (7.6%) was higher than the overall CFR for 55,924 COVID-19 patients in China [19•]. |
| T93 | 398-500 | Sentence | denotes | Reports from Italy and Washington also support that cancer patients had similar findings [14, 22, 23]. |
| T94 | 501-607 | Sentence | denotes | However, the specific type of cancer was neither reported in these studies nor linked to specific outcome. |
| T95 | 608-700 | Sentence | denotes | Several studies have indicated that cancer patients trend toward having more severe disease. |
| T96 | 701-872 | Sentence | denotes | A case series of patients admitted to New York hospitals identified that 5.9% patients had cancer and 43% of these patients required invasive ventilation for support [24]. |
| T97 | 873-1051 | Sentence | denotes | A prospective cohort study of following 1590 COVID-19 patients in China demonstrated that of the 18 patients with cancer, lung cancer was the most frequently incurred malignancy. |
| T98 | 1052-1312 | Sentence | denotes | Moreover, in this cohort, history of cancer was associated with a higher risk of severe events (ICU admission requiring ventilation or death) and faster progression to severe events (median time for cancer patients 13 days vs. 43 days for non-cancer patients). |
| T99 | 1313-1511 | Sentence | denotes | Those with a history of chemotherapy or surgery in the past month had a higher risk for severe events even when adjusted for other risk factors including age (OR 5.34, 95% CI 1.80–16.18; p < 0.005). |
| T100 | 1512-1612 | Sentence | denotes | Of the 18 described in the Wuhan group, roughly 10% received chemotherapy and 7.1% targeted therapy. |
| T101 | 1613-1718 | Sentence | denotes | However, age alone was also an independent risk factor for severe events in the cancer group of patients. |
| T102 | 1719-1822 | Sentence | denotes | Those with history of lung cancer versus other cancer types did not predict a more severe outcome [42]. |
| T103 | 1823-2042 | Sentence | denotes | Another study from China evaluating all cancer patients admitted to Zhongnan Hospital of Wuhan University determined that cancer patients had a 0.79% infection rate compared with the overall city’s 0.37% infection rate. |
| T104 | 2043-2259 | Sentence | denotes | A total of 12 patients were affected, 58.3% had non-small cell lung carcinoma (NSCLC) with approximately 41.7% were undergoing treatment with chemotherapy and resulting mortality rate as of March 10, 2020, being 25%. |
| T105 | 2260-2402 | Sentence | denotes | Additionally, NSCLC patients that were greater than age 60 had a higher incidence of COVID-19 compared with younger patients with NSCLC [43•]. |
| T106 | 2403-2524 | Sentence | denotes | These findings are further corroborated by a study that examined all 28 cancer patients admitted to 3 hospitals in China. |
| T107 | 2525-2596 | Sentence | denotes | Lung cancer was the most common cancer type among these patients (25%). |
| T108 | 2597-2719 | Sentence | denotes | Diabetes (14.3%) and chronic cardiovascular and cerebrovascular disease (14.3%) were the most common comorbidities listed. |
| T109 | 2720-2915 | Sentence | denotes | Clinical factors that significantly predicted worse outcomes in this group of patients included age, patchy consolidation on imaging, and receipt of anti-tumor treatment in the last 14 days [44]. |
| T110 | 2916-3078 | Sentence | denotes | These studies suggest that patients with cancer are at higher risk for COVID-19, and those with older age and cancer are at an even higher risk for poor outcomes. |
| T111 | 3079-3321 | Sentence | denotes | Lung cancer has been reported to be more common in these studies, but the total sample size of cancer patients remains too low to draw any meaningful conclusions on which malignancy may be most associated with severity of COVID-19 infections. |
| T112 | 3322-3560 | Sentence | denotes | Lastly, although having recent anti-cancer treatment increases the risk for severe outcomes, it is unclear which anti-cancer agents are associated with higher risk for acquiring COVID-19 infection, severity of infection, and/or mortality. |
| T113 | 3561-3716 | Sentence | denotes | Table 1 demonstrates a literature review of studies published until April 26, 2020 that identify the prevalence of cancer among COVID-19 infected patients. |
| T114 | 3717-3818 | Sentence | denotes | Table 1 COVID-19 Studies with cancer and cardiovascular disease epidemiology (through April 22, 2020) |
| T115 | 3819-4028 | Sentence | denotes | Author Country Clinical setting Number of institutions Date of publication Number of patients in study with COVID-19 Canceran (%) Predominant cancer n (%) HTN n (%) CVDbn (%) Mortality in cancer patients n (%) |
| T116 | 4029-4041 | Sentence | denotes | Wu C, et al. |
| T117 | 4042-4132 | Sentence | denotes | China Hospitalized 1 March 13,2020 201 1(0.5) Not specified 39 (19.4) 8 (4.0) Not reported |
| T118 | 4133-4146 | Sentence | denotes | Guo T, et al. |
| T119 | 4147-4239 | Sentence | denotes | China Hospitalized 1 March 27, 2020 187 13(7) Not specified 61 (32.6) 29 (15.5) Not reported |
| T120 | 4240-4254 | Sentence | denotes | Zhou F, et al. |
| T121 | 4255-4331 | Sentence | denotes | China Hospitalized 2 March 9, 2020 191 2(1) Not specified 58 (30.4) 15 (8) 0 |
| T122 | 4332-4345 | Sentence | denotes | Shi S, et al. |
| T123 | 4346-4440 | Sentence | denotes | China Hospitalized 1 March 25, 2020 416 9(2.2) Not specified 127 (30.5) 61 (14.7) Not reported |
| T124 | 4441-4456 | Sentence | denotes | Liang W, et al. |
| T125 | 4457-4563 | Sentence | denotes | China Hospitalized 575 February 14, 2020 1590 18(1.1) Lung - 5 (28) Not reported Not reported Not reported |
| T126 | 4564-4579 | Sentence | denotes | Onder G, et al. |
| T127 | 4580-4721 | Sentence | denotes | Italy Not specified Not specified March 23, 2020 355 72 (20.3) Not specified Not specified 117 (33) 100 (Study only reviewed cases that died) |
| T128 | 4722-4842 | Sentence | denotes | Grasselli G, et al.c Italy Intensive care units 72 April 6, 2020 1043 81(8) Not specified 509 (49) 223 (21) Not reported |
| T129 | 4843-4862 | Sentence | denotes | McMichael T, et al. |
| T130 | 4863-4964 | Sentence | denotes | USA Long-term care facility 1 March 27, 2020 167 15(9) Not specified 74 (44.3) 68 (40.7) Not reported |
| T131 | 4965-4980 | Sentence | denotes | Goyal P, et al. |
| T132 | 4981-5072 | Sentence | denotes | USA Hospitalized 2 April 17, 2020 393 23(5.9) Not specified 197 (50.1) 82 (21) Not reported |
| T133 | 5073-5091 | Sentence | denotes | Richardson, et al. |
| T134 | 5092-5188 | Sentence | denotes | USA Hospitalized 17 April 22, 2020 5700 320(6) Not specified 3026 (56.6)c 966 (18)d Not reported |
| T135 | 5189-5278 | Sentence | denotes | aCancer was defined in studies as either cancer, tumor, malignant neoplasm, or carcinoma. |
| T136 | 5279-5345 | Sentence | denotes | There was variability in whether cancer was active or in remission |
| T137 | 5346-5515 | Sentence | denotes | bThere were various definitions utilized for cardiovascular disease across all studies not limited to cardiomyopathy, coronary artery disease, and ischemic heart disease |
| T138 | 5516-5708 | Sentence | denotes | c,dHistory regarding these comorbidities may not have been available for all patients enrolled in the study; hence, percentage does not correlate the with total number of patients in the study |
| T139 | 5709-5753 | Sentence | denotes | HTN hypertension, CVD cardiovascular disease |
| T140 | 5754-6025 | Sentence | denotes | Although no formal studies have assessed the direct impact of COVID-19 on cardio-oncology patients, a study has shown that both CVD patients and cancer patients do have an increased risk for cardiac injury which in of itself is an independent predictor of mortality [28]. |
| T141 | 6026-6279 | Sentence | denotes | Additionally, since the data suggests that CVD and cancer are potentially independent risk factors for virus acquisition and severe outcomes, it is reasonable to assume that if patients have both risk factors, then they may posit higher cumulative risk. |
| T142 | 6280-6485 | Sentence | denotes | There is also concern that cancer treatments may induce disease states such as hypertension and cardiovascular disease—both frequently associated risk factors for worse outcomes in COVID-19 patients [19•]. |
| T143 | 6486-6726 | Sentence | denotes | An example of such a clinical scenario could involve metastatic renal carcinoma patients who develop hypertension from anti-VEGF tyrosine kinase therapy, or cardiomyopathy from anti-HER2, and anthracycline therapy of breast cancer [45, 46]. |
| T144 | 6727-7020 | Sentence | denotes | However, the definition of “cardiovascular disease” that patients have been classified with in these studies is not always clearly delineated; thus, risk stratification of these patients in regard to COVID-19 risk requires more refined investigation and long-term follow-up regarding outcomes. |
| T145 | 7021-7116 | Sentence | denotes | The elevated risk that cancer patients face during the COVID-19 pandemic poses many challenges. |
| T146 | 7117-7430 | Sentence | denotes | Some of these include providing ongoing cancer treatments especially if patients are undergoing curative therapy, enrolling patients into experimental drug trials, continuing close cardiotoxicity surveillance, and providing treatments to patients who have an optimal window of adequate functional status [47, 48]. |
| T147 | 7431-7668 | Sentence | denotes | Given concerns for hospital-acquired COVID-19 infections, this additional risk factor can impact continuation of therapy or initiation of regimens for aggressive malignancy that require hospitalization for closer monitoring [43, 47, 48]. |
| T148 | 7669-7887 | Sentence | denotes | Moreover, patients that may rely on drugs or stem cell donations for treatment may necessitate access to unique global sources and are rendered at a disadvantage due to travel restrictions and quarantine policies [49]. |
| T149 | 7888-8127 | Sentence | denotes | In response to these climactic changes, The National Comprehensive Cancer Network and National Cancer Institute have provided guidance to providers on providing care to oncology patients, resource allocation, and managing drug trials [50]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32462289-32066541-24380944 | 247-249 | 32066541 | denotes | 42 |
| 32462289-32220208-24380945 | 496-498 | 32220208 | denotes | 23 |
| 32462289-32066541-24380946 | 1818-1820 | 32066541 | denotes | 42 |
| 32462289-27732808-24380947 | 6722-6724 | 27732808 | denotes | 46 |
| 32462289-32213339-24380948 | 7883-7885 | 32213339 | denotes | 49 |