PMC:7253233 / 8351-10596
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
293 | 834-852 | Gene | denotes | C-reactive protein | Gene:1401 |
294 | 20-27 | Species | denotes | patient | Tax:9606 |
295 | 473-480 | Species | denotes | patient | Tax:9606 |
296 | 1792-1800 | Species | denotes | patients | Tax:9606 |
297 | 1929-1936 | Species | denotes | Patient | Tax:9606 |
298 | 767-771 | Chemical | denotes | urea | MESH:D014508 |
299 | 772-780 | Chemical | denotes | nitrogen | MESH:D009584 |
300 | 797-807 | Chemical | denotes | creatinine | MESH:D003404 |
301 | 1460-1473 | Chemical | denotes | levetiracetam | MESH:D000077287 |
302 | 33-70 | Disease | denotes | chronic obstructive pulmonary disease | MESH:D029424 |
303 | 72-101 | Disease | denotes | venous thromboembolic disease | MESH:D054556 |
304 | 112-123 | Disease | denotes | heart block | MESH:D006327 |
305 | 129-151 | Disease | denotes | chronic kidney disease | MESH:D051436 |
306 | 227-234 | Disease | denotes | dyspnea | MESH:D004417 |
307 | 304-311 | Disease | denotes | hypoxic | MESH:D000860 |
308 | 376-395 | Disease | denotes | respiratory failure | MESH:D012131 |
309 | 456-467 | Disease | denotes | pneumonitis | MESH:D011014 |
310 | 523-534 | Disease | denotes | lymphopenia | MESH:D008231 |
311 | 584-596 | Disease | denotes | coagulopathy | MESH:D001778 |
312 | 711-727 | Disease | denotes | thrombocytopenia | MESH:D013921 |
313 | 740-759 | Disease | denotes | acute kidney injury | MESH:D058186 |
314 | 964-972 | Disease | denotes | COVID-19 | MESH:C000657245 |
315 | 1208-1216 | Disease | denotes | seizures | MESH:D012640 |
316 | 1346-1364 | Disease | denotes | status epilepticus | MESH:D013226 |
317 | 1382-1390 | Disease | denotes | seizures | MESH:D012640 |
318 | 1400-1410 | Disease | denotes | convulsive | MESH:D012640 |
319 | 1412-1419 | Disease | denotes | Seizure | MESH:D012640 |
320 | 1818-1831 | Disease | denotes | kidney injury | MESH:D058186 |
321 | 1895-1907 | Disease | denotes | coagulopathy | MESH:D001778 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T42 | 112-117 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
T43 | 137-143 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T44 | 244-250 | Body_part | denotes | mental | http://purl.org/sig/ont/fma/fma264279 |
T45 | 403-408 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T46 | 423-427 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T47 | 560-570 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T48 | 746-752 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T49 | 761-766 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
T50 | 845-852 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T51 | 1135-1141 | Body_part | denotes | eyelid | http://purl.org/sig/ont/fma/fma54437 |
T52 | 1493-1498 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
T53 | 1552-1564 | Body_part | denotes | white matter | http://purl.org/sig/ont/fma/fma83929 |
T54 | 1677-1682 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
T55 | 1716-1733 | Body_part | denotes | cardiac pacemaker | http://purl.org/sig/ont/fma/fma9477 |
T56 | 1818-1824 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T32 | 112-117 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
T33 | 137-143 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
T34 | 403-408 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T35 | 423-427 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T36 | 746-752 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
T37 | 761-766 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
T38 | 1135-1141 | Body_part | denotes | eyelid | http://purl.obolibrary.org/obo/UBERON_0001711 |
T39 | 1493-1498 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
T40 | 1552-1564 | Body_part | denotes | white matter | http://purl.obolibrary.org/obo/UBERON_0002316 |
T41 | 1677-1682 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
T42 | 1743-1749 | Body_part | denotes | vessel | http://purl.obolibrary.org/obo/UBERON_0000055 |
T43 | 1818-1824 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T69 | 33-70 | Disease | denotes | chronic obstructive pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005002 |
T70 | 53-70 | Disease | denotes | pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
T71 | 72-93 | Disease | denotes | venous thromboembolic | http://purl.obolibrary.org/obo/MONDO_0005399 |
T72 | 103-123 | Disease | denotes | complete heart block | http://purl.obolibrary.org/obo/MONDO_0000468 |
T73 | 129-151 | Disease | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/MONDO_0005300 |
T74 | 137-151 | Disease | denotes | kidney disease | http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240 |
T76 | 376-395 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
T77 | 456-467 | Disease | denotes | pneumonitis | http://purl.obolibrary.org/obo/MONDO_0043905 |
T78 | 523-534 | Disease | denotes | lymphopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
T79 | 584-596 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
T80 | 711-727 | Disease | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0002049 |
T81 | 740-759 | Disease | denotes | acute kidney injury | http://purl.obolibrary.org/obo/MONDO_0002492 |
T82 | 753-759 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T83 | 964-972 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T84 | 1346-1364 | Disease | denotes | status epilepticus | http://purl.obolibrary.org/obo/MONDO_0002125 |
T85 | 1825-1831 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T86 | 1895-1907 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T89 | 15-19 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
T90 | 15-19 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
T91 | 112-117 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
T92 | 112-117 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
T93 | 112-117 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
T94 | 112-117 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
T95 | 137-143 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T96 | 137-143 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T97 | 137-143 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T98 | 195-199 | http://purl.obolibrary.org/obo/CLO_0001550 | denotes | a 10 |
T99 | 401-402 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T100 | 403-408 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T101 | 423-427 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T102 | 423-427 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T103 | 729-732 | http://purl.obolibrary.org/obo/CLO_0054061 | denotes | 132 |
T104 | 746-752 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T105 | 746-752 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T106 | 746-752 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T107 | 761-766 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T108 | 761-766 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
T109 | 901-902 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T110 | 955-959 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T111 | 1475-1476 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T112 | 1493-1498 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
T113 | 1493-1498 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
T114 | 1677-1682 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
T115 | 1677-1682 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
T116 | 1743-1749 | http://purl.obolibrary.org/obo/UBERON_0000055 | denotes | vessel |
T117 | 1818-1824 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T118 | 1818-1824 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T119 | 1818-1824 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T120 | 1833-1834 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T121 | 2144-2145 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T122 | 2183-2194 | http://purl.obolibrary.org/obo/UBERON_0001353 | denotes | posteriorly |
T123 | 2196-2197 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T17 | 15-19 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
T18 | 669-672 | Chemical | denotes | PTT | http://purl.obolibrary.org/obo/CHEBI_3088 |
T19 | 767-771 | Chemical | denotes | urea | http://purl.obolibrary.org/obo/CHEBI_16199 |
T20 | 772-780 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
T21 | 797-807 | Chemical | denotes | creatinine | http://purl.obolibrary.org/obo/CHEBI_16737 |
T22 | 845-852 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T23 | 1063-1066 | Chemical | denotes | EEG | http://purl.obolibrary.org/obo/CHEBI_73494 |
T24 | 1204-1207 | Chemical | denotes | EEG | http://purl.obolibrary.org/obo/CHEBI_73494 |
T25 | 1460-1473 | Chemical | denotes | levetiracetam | http://purl.obolibrary.org/obo/CHEBI_6437 |
T26 | 1918-1921 | Chemical | denotes | PTT | http://purl.obolibrary.org/obo/CHEBI_3088 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T49 | 33-70 | Phenotype | denotes | chronic obstructive pulmonary disease | http://purl.obolibrary.org/obo/HP_0006510 |
T50 | 79-101 | Phenotype | denotes | thromboembolic disease | http://purl.obolibrary.org/obo/HP_0001907 |
T51 | 103-123 | Phenotype | denotes | complete heart block | http://purl.obolibrary.org/obo/HP_0001709 |
T52 | 129-151 | Phenotype | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/HP_0012622 |
T53 | 227-234 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
T54 | 263-283 | Phenotype | denotes | generalized weakness | http://purl.obolibrary.org/obo/HP_0003324 |
T55 | 376-395 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
T56 | 423-439 | Phenotype | denotes | lung infiltrates | http://purl.obolibrary.org/obo/HP_0002113 |
T57 | 523-534 | Phenotype | denotes | lymphopenia | http://purl.obolibrary.org/obo/HP_0001888 |
T58 | 584-596 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
T59 | 681-697 | Phenotype | denotes | elevated D-dimer | http://purl.obolibrary.org/obo/HP_0033106 |
T60 | 711-727 | Phenotype | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/HP_0001873 |
T61 | 740-759 | Phenotype | denotes | acute kidney injury | http://purl.obolibrary.org/obo/HP_0001919 |
T62 | 1153-1162 | Phenotype | denotes | twitching | http://purl.obolibrary.org/obo/HP_0010546 |
T63 | 1208-1216 | Phenotype | denotes | seizures | http://purl.obolibrary.org/obo/HP_0001250 |
T64 | 1346-1364 | Phenotype | denotes | status epilepticus | http://purl.obolibrary.org/obo/HP_0002133 |
T65 | 1382-1390 | Phenotype | denotes | seizures | http://purl.obolibrary.org/obo/HP_0001250 |
T66 | 1412-1419 | Phenotype | denotes | Seizure | http://purl.obolibrary.org/obo/HP_0001250 |
T67 | 1895-1907 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T66 | 0-284 | Sentence | denotes | An 82-year-old male patient with chronic obstructive pulmonary disease, venous thromboembolic disease, complete heart block, and chronic kidney disease presented to the emergency department with a 10-day history of progressive dyspnea, altered mental status, and generalized weakness. |
T67 | 285-338 | Sentence | denotes | He was found to be hypoxic, febrile, and tachycardic. |
T68 | 339-468 | Sentence | denotes | He was intubated for acute hypoxemic respiratory failure with a chest X-ray showing lung infiltrates consistent with pneumonitis. |
T69 | 469-900 | Sentence | denotes | The patient’s laboratory results were significant for lymphopenia (WBC 3.26 k/μl, absolute lymphocyte count 0.70), coagulopathy (international normalised ratio (INR) 2.5, partial thromboplastin time (PTT) 53.9), elevated D-dimer (590 ng/mL), thrombocytopenia (132 k/μl), acute kidney injury (blood urea nitrogen (BUN) 47 mg/dL, creatinine 3.96 mg/dL), and elevated C-reactive protein initially 12.5 mg/L and increased to 26.2 mg/L. |
T70 | 901-1023 | Sentence | denotes | A nasopharyngeal swab polymerase chain reaction (PCR) test for COVID-19 was sent on admission and was positive 24 h later. |
T71 | 1024-1194 | Sentence | denotes | Continuous video electroencephalogram (EEG) monitoring was ordered on day 5 of admission after events of right eyelid and facial twitching were observed by the care team. |
T72 | 1195-1365 | Sentence | denotes | Frequent EEG seizures were captured independently from the left more than right frontal–temporal regions (Fig. 3) which eventually progressed to focal status epilepticus. |
T73 | 1366-1411 | Sentence | denotes | The majority of seizures were non-convulsive. |
T74 | 1412-1474 | Sentence | denotes | Seizure frequency improved after treatment with levetiracetam. |
T75 | 1475-1647 | Sentence | denotes | A non-contrast CT-brain demonstrated hypodensities within the supratentorial white matter, consistent with mild microvascular disease but without acute intracranial lesion. |
T76 | 1648-1734 | Sentence | denotes | He was unable to have an MRI brain performed due to an incompatible cardiac pacemaker. |
T77 | 1735-1832 | Sentence | denotes | Further vessel imaging was unable to be performed due to patients acute on chronic kidney injury. |
T78 | 1833-1928 | Sentence | denotes | A lumbar puncture was unable to be performed due to worsening coagulopathy (INR 3.8, PTT 73.5). |
T79 | 1929-2055 | Sentence | denotes | Patient remained on the ventilator, and after 20 days of ICU stay, the family opted for withdrawal of life-sustaining support. |
T80 | 2056-2086 | Sentence | denotes | Fig. 3 Electroencephalography. |
T81 | 2087-2245 | Sentence | denotes | Rhythmic discharges evolving in the left frontotemporal (a) region and spreading anteriorly and posteriorly (b) corresponding to right facial clonic movements |