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PMC:7253233 / 2649-4886 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
137 13-60 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
138 62-72 Species denotes SARS-CoV-2 Tax:2697049
139 235-245 Species denotes SARS-CoV-2 Tax:2697049
140 674-682 Species denotes patients Tax:9606
141 735-743 Species denotes patients Tax:9606
142 913-921 Species denotes patients Tax:9606
143 1060-1068 Species denotes patients Tax:9606
144 1166-1174 Species denotes patients Tax:9606
145 1319-1327 Species denotes patients Tax:9606
146 1533-1541 Species denotes patients Tax:9606
147 257-281 Disease denotes Coronavirus disease 2019 MESH:C000657245
148 283-291 Disease denotes COVID-19 MESH:C000657245
149 688-696 Disease denotes COVID-19 MESH:C000657245
150 749-757 Disease denotes COVID-19 MESH:C000657245
151 781-797 Disease denotes systemic disease MESH:D034721
152 824-853 Disease denotes acute cerebrovascular disease MESH:D002561
153 855-875 Disease denotes acute encephalopathy MESH:D001927
154 881-905 Disease denotes skeletal muscle symptoms MESH:D004421
155 993-1012 Disease denotes multi-organ failure MESH:D009102
156 1074-1088 Disease denotes encephalopathy MESH:D001927
157 1138-1146 Disease denotes seizures MESH:D012640
158 1242-1256 Disease denotes encephalopathy MESH:D001927
159 1431-1445 Disease denotes encephalopathy MESH:D001927
160 1451-1459 Disease denotes Seizures MESH:D012640
161 1505-1513 Disease denotes COVID-19 MESH:C000657245
162 1564-1576 Disease denotes brain injury MESH:D001930
163 1580-1588 Disease denotes epilepsy MESH:D004827
174 1650-1658 Species denotes patients Tax:9606
175 1828-1835 Species denotes patient Tax:9606
176 1923-1931 Species denotes patients Tax:9606
177 2005-2013 Species denotes patients Tax:9606
178 1664-1684 Disease denotes SARS-CoV-2 infection MESH:C000657245
179 1914-1922 Disease denotes COVID-19 MESH:C000657245
180 2062-2076 Disease denotes encephalopathy MESH:D001927
181 2081-2088 Disease denotes seizure MESH:D012640
182 2188-2196 Disease denotes seizures MESH:D012640
183 2220-2228 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T12 465-487 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T13 489-492 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T14 890-896 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T15 999-1004 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T16 1261-1280 Body_part denotes corticospinal tract http://purl.org/sig/ont/fma/fma265580
T17 1564-1569 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T18 2129-2134 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T13 465-487 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T14 473-487 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T15 489-492 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T16 999-1004 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T17 1261-1280 Body_part denotes corticospinal tract http://purl.obolibrary.org/obo/UBERON_0002707
T18 1564-1569 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T19 2129-2134 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T26 13-60 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T27 62-70 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 235-243 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 257-281 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T30 283-291 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 688-696 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 749-757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 781-797 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T34 830-853 Disease denotes cerebrovascular disease http://purl.obolibrary.org/obo/MONDO_0011057
T35 861-875 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T36 993-1012 Disease denotes multi-organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T37 1074-1088 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T38 1242-1256 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T39 1431-1445 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T40 1505-1513 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 1564-1576 Disease denotes brain injury http://purl.obolibrary.org/obo/MONDO_0043510
T42 1570-1576 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T43 1580-1588 Disease denotes epilepsy http://purl.obolibrary.org/obo/MONDO_0005027
T44 1664-1672 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 1675-1684 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 1914-1922 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 2062-2076 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T48 2220-2228 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T27 145-146 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 313-325 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T29 446-449 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T30 465-487 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T31 465-487 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T32 465-487 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T33 489-492 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T34 489-492 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T35 489-492 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T36 881-896 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T37 881-896 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T38 881-896 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T39 999-1004 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T40 1293-1294 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 1495-1496 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T42 1564-1569 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T43 1564-1569 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T44 1787-1788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 2094-2102 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T46 2129-2134 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T47 2129-2134 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T20 855-875 Phenotype denotes acute encephalopathy http://purl.obolibrary.org/obo/HP_0006846
T21 1074-1088 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T22 1126-1146 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T23 1242-1256 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T24 1431-1445 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T25 1451-1459 Phenotype denotes Seizures http://purl.obolibrary.org/obo/HP_0001250
T26 1580-1588 Phenotype denotes epilepsy http://purl.obolibrary.org/obo/HP_0001250
T27 2056-2076 Phenotype denotes acute encephalopathy http://purl.obolibrary.org/obo/HP_0006846
T28 2081-2088 Phenotype denotes seizure http://purl.obolibrary.org/obo/HP_0001250
T29 2176-2196 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T26 0-12 Sentence denotes Introduction
T27 13-184 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged first in Wuhan, China, in 2019 and spread rapidly worldwide as a pandemic of the twenty-first century.
T28 185-330 Sentence denotes The symptoms and disease manifestations caused by SARS-CoV-2 were named Coronavirus disease 2019 (COVID-19) by the World Health Organization [1].
T29 331-562 Sentence denotes The neurological manifestations of this disease are not well known, and there is growing evidence that the disease has effects on the central nervous system (CNS) as detailed in retrospective reports from several centers worldwide.
T30 563-709 Sentence denotes An initial retrospective case series from Wuhan, China, showed that neurological manifestations are present in patients with COVID-19 disease [2].
T31 710-906 Sentence denotes In that series, 45.5% of patients with COVID-19 disease who had severe systemic disease burden also suffered from acute cerebrovascular disease, acute encephalopathy, and skeletal muscle symptoms.
T32 907-1013 Sentence denotes These patients also had higher levels of inflammatory markers and greater evidence of multi-organ failure.
T33 1014-1147 Sentence denotes However, the study did not elucidate how many patients with encephalopathy were monitored and treated for acute symptomatic seizures.
T34 1148-1287 Sentence denotes Another series of patients were reported in Strasbourg, France, with neurological features of encephalopathy and corticospinal tract signs.
T35 1288-1450 Sentence denotes Only a small proportion of the patients (8 out of 64) had electroencephalography performed, which demonstrated diffuse slowing consistent with encephalopathy [3].
T36 1451-1589 Sentence denotes Seizures have not been directly reported as a part of COVID-19 disease outside of patients with previously known brain injury or epilepsy.
T37 1590-1847 Sentence denotes There are several barriers to electrographically monitoring patients with SARS-CoV-2 infection such as prone positioning for respiratory compromise as well as the contamination risk which obviates a need for minimizing procedures in this patient population.
T38 1848-1972 Sentence denotes Neurointensivists and neurologists are often consulted for severe COVID-19 patients that present with neurological features.
T39 1973-2237 Sentence denotes In this report, we describe two patients who were electrographically monitored for acute encephalopathy and seizure-like activity, in the setting of normal brain imaging and who were found to have acute symptomatic seizures associated with severe COVID-19 disease.

2_test

Id Subject Object Predicate Lexical cue
32462412-32257431-75539777 327-328 32257431 denotes 1
32462412-32453517-75539778 1447-1448 32453517 denotes 3