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PMC:7253233 / 2649-15257 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
137 13-60 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
138 62-72 Species denotes SARS-CoV-2 Tax:2697049
139 235-245 Species denotes SARS-CoV-2 Tax:2697049
140 674-682 Species denotes patients Tax:9606
141 735-743 Species denotes patients Tax:9606
142 913-921 Species denotes patients Tax:9606
143 1060-1068 Species denotes patients Tax:9606
144 1166-1174 Species denotes patients Tax:9606
145 1319-1327 Species denotes patients Tax:9606
146 1533-1541 Species denotes patients Tax:9606
147 257-281 Disease denotes Coronavirus disease 2019 MESH:C000657245
148 283-291 Disease denotes COVID-19 MESH:C000657245
149 688-696 Disease denotes COVID-19 MESH:C000657245
150 749-757 Disease denotes COVID-19 MESH:C000657245
151 781-797 Disease denotes systemic disease MESH:D034721
152 824-853 Disease denotes acute cerebrovascular disease MESH:D002561
153 855-875 Disease denotes acute encephalopathy MESH:D001927
154 881-905 Disease denotes skeletal muscle symptoms MESH:D004421
155 993-1012 Disease denotes multi-organ failure MESH:D009102
156 1074-1088 Disease denotes encephalopathy MESH:D001927
157 1138-1146 Disease denotes seizures MESH:D012640
158 1242-1256 Disease denotes encephalopathy MESH:D001927
159 1431-1445 Disease denotes encephalopathy MESH:D001927
160 1451-1459 Disease denotes Seizures MESH:D012640
161 1505-1513 Disease denotes COVID-19 MESH:C000657245
162 1564-1576 Disease denotes brain injury MESH:D001930
163 1580-1588 Disease denotes epilepsy MESH:D004827
174 1650-1658 Species denotes patients Tax:9606
175 1828-1835 Species denotes patient Tax:9606
176 1923-1931 Species denotes patients Tax:9606
177 2005-2013 Species denotes patients Tax:9606
178 1664-1684 Disease denotes SARS-CoV-2 infection MESH:C000657245
179 1914-1922 Disease denotes COVID-19 MESH:C000657245
180 2062-2076 Disease denotes encephalopathy MESH:D001927
181 2081-2088 Disease denotes seizure MESH:D012640
182 2188-2196 Disease denotes seizures MESH:D012640
183 2220-2228 Disease denotes COVID-19 MESH:C000657245
203 3126-3133 Species denotes patient Tax:9606
204 3161-3171 Chemical denotes vancomycin MESH:D014640
205 3176-3199 Chemical denotes piperacillin–tazobactam MESH:D000077725
206 2290-2312 Disease denotes asthma on benralizumab MESH:D001249
207 2314-2326 Disease denotes hypertension MESH:D006973
208 2328-2350 Disease denotes chronic kidney disease MESH:D051436
209 2352-2366 Disease denotes hyperlipidemia MESH:D006949
210 2368-2392 Disease denotes left bundle branch block MESH:D002037
211 2394-2415 Disease denotes diastolic dysfunction MESH:D007022
212 2532-2536 Disease denotes pain MESH:D010146
213 2538-2543 Disease denotes fever MESH:D005334
214 2576-2590 Disease denotes encephalopathy MESH:D001927
215 2640-2671 Disease denotes acute lumbosacral radiculopathy MESH:D011843
216 2727-2752 Disease denotes neutrophilic leukocytosis MESH:D007964
217 2790-2794 Disease denotes coma MESH:D003128
218 2899-2926 Disease denotes focal neurological deficits MESH:D009461
219 3286-3298 Disease denotes leukocytosis MESH:D007964
220 3332-3338 Disease denotes fevers MESH:D005334
221 3359-3378 Disease denotes respiratory failure MESH:D012131
223 5612-5619 Species denotes red box Tax:1226038
244 5118-5136 Gene denotes C-reactive protein Gene:1401
245 4977-4987 Gene denotes fibrinogen Gene:2244
246 3758-3765 Species denotes patient Tax:9606
247 5355-5362 Species denotes patient Tax:9606
248 4129-4142 Chemical denotes Levetiracetam MESH:D000077287
249 4257-4267 Chemical denotes Vancomycin MESH:D014640
250 4269-4278 Chemical denotes Meropenem MESH:D000077731
251 4284-4293 Chemical denotes Acyclovir MESH:D000212
252 3846-3860 Disease denotes encephalopathy MESH:D001927
253 3926-3936 Disease denotes drowsiness MESH:D006970
254 4033-4041 Disease denotes seizures MESH:D012640
255 4194-4201 Disease denotes seizure MESH:D012640
256 4406-4435 Disease denotes white matter hyperintensities MESH:D056784
257 4498-4521 Disease denotes venous sinus thrombosis MESH:D012851
258 4527-4545 Disease denotes C5–C6 myelomalacia MESH:C537005
259 4622-4631 Disease denotes infection MESH:D007239
260 4676-4682 Disease denotes fevers MESH:D005334
261 4843-4851 Disease denotes COVID-19 MESH:C000657245
262 4905-4913 Disease denotes COVID-19 MESH:C000657245
263 5385-5397 Disease denotes tracheostomy
293 6536-6554 Gene denotes C-reactive protein Gene:1401
294 5722-5729 Species denotes patient Tax:9606
295 6175-6182 Species denotes patient Tax:9606
296 7494-7502 Species denotes patients Tax:9606
297 7631-7638 Species denotes Patient Tax:9606
298 6469-6473 Chemical denotes urea MESH:D014508
299 6474-6482 Chemical denotes nitrogen MESH:D009584
300 6499-6509 Chemical denotes creatinine MESH:D003404
301 7162-7175 Chemical denotes levetiracetam MESH:D000077287
302 5735-5772 Disease denotes chronic obstructive pulmonary disease MESH:D029424
303 5774-5803 Disease denotes venous thromboembolic disease MESH:D054556
304 5814-5825 Disease denotes heart block MESH:D006327
305 5831-5853 Disease denotes chronic kidney disease MESH:D051436
306 5929-5936 Disease denotes dyspnea MESH:D004417
307 6006-6013 Disease denotes hypoxic MESH:D000860
308 6078-6097 Disease denotes respiratory failure MESH:D012131
309 6158-6169 Disease denotes pneumonitis MESH:D011014
310 6225-6236 Disease denotes lymphopenia MESH:D008231
311 6286-6298 Disease denotes coagulopathy MESH:D001778
312 6413-6429 Disease denotes thrombocytopenia MESH:D013921
313 6442-6461 Disease denotes acute kidney injury MESH:D058186
314 6666-6674 Disease denotes COVID-19 MESH:C000657245
315 6910-6918 Disease denotes seizures MESH:D012640
316 7048-7066 Disease denotes status epilepticus MESH:D013226
317 7084-7092 Disease denotes seizures MESH:D012640
318 7102-7112 Disease denotes convulsive MESH:D012640
319 7114-7121 Disease denotes Seizure MESH:D012640
320 7520-7533 Disease denotes kidney injury MESH:D058186
321 7597-7609 Disease denotes coagulopathy MESH:D001778
351 7964-7982 Species denotes SARS-Coronavirus-2 Tax:2697049
352 7998-8011 Species denotes β-coronavirus Tax:694002
353 8041-8046 Species denotes human Tax:9606
354 8076-8127 Species denotes middle east respiratory syndrome (MERS) coronavirus Tax:1335626
355 8132-8140 Species denotes SARS-CoV Tax:694009
356 8159-8172 Species denotes coronaviruses Tax:11118
357 8364-8374 Species denotes SARS-CoV-2 Tax:2697049
358 8408-8416 Species denotes patients Tax:9606
359 8703-8711 Species denotes patients Tax:9606
360 8193-8213 Disease denotes respiratory symptoms MESH:D012818
361 8226-8247 Disease denotes neurological symptoms MESH:D009422
362 8258-8266 Disease denotes delirium MESH:D003693
363 8268-8277 Disease denotes dizziness MESH:D004244
364 8283-8292 Disease denotes headaches MESH:D006261
365 8328-8350 Disease denotes coronavirus infections MESH:D018352
366 8441-8449 Disease denotes COVID-19 MESH:C000657245
367 8531-8539 Disease denotes headache MESH:D006261
368 8541-8550 Disease denotes dizziness MESH:D004244
369 8552-8574 Disease denotes impaired consciousness MESH:D003244
370 8576-8599 Disease denotes cerebrovascular disease MESH:D002561
371 8605-8614 Disease denotes neuralgia MESH:D009437
372 8621-8629 Disease denotes Seizures MESH:D012640
373 8677-8697 Disease denotes SARS-CoV-2 infection MESH:C000657245
374 8752-8760 Disease denotes seizures MESH:D012640
375 8809-8838 Disease denotes convulsive status epilepticus MESH:D013226
376 8840-8848 Disease denotes Seizures MESH:D012640
377 8879-8887 Disease denotes COVID-19 MESH:C000657245
378 8961-8982 Disease denotes neurological symptoms MESH:D009422
379 8986-9006 Disease denotes SARS-CoV-2 infection MESH:C000657245
401 9008-9013 Species denotes Human Tax:9606
402 9014-9027 Species denotes coronaviruses Tax:11118
403 9067-9072 Species denotes human Tax:9606
404 9170-9175 Species denotes human Tax:9606
405 9454-9464 Species denotes SARS-Cov-2 Tax:2697049
406 9596-9604 Species denotes patients Tax:9606
407 9703-9708 Species denotes human Tax:9606
408 9709-9722 Species denotes coronaviruses Tax:11118
409 9724-9727 Species denotes CoV Tax:11118
410 9734-9739 Species denotes CoV-2 Tax:2697049
411 9971-9979 Species denotes patients Tax:9606
412 10201-10211 Species denotes SARS-CoV-2 Tax:2697049
413 10321-10329 Species denotes patients Tax:9606
414 9278-9298 Disease denotes SARS-CoV-1 infection MESH:C000657245
415 9571-9592 Disease denotes neurological symptoms MESH:D009422
416 9610-9618 Disease denotes COVID-19 MESH:C000657245
417 9800-9808 Disease denotes seizures MESH:D012640
418 9907-9923 Disease denotes systemic disease MESH:D034721
419 9992-10000 Disease denotes COVID-19 MESH:C000657245
420 10333-10341 Disease denotes seizures MESH:D012640
421 10359-10380 Disease denotes neurological diseases MESH:D020271
444 10552-10565 Gene denotes interleukin-8 Gene:3576
445 10567-10570 Gene denotes IL8 Gene:3576
446 10576-10610 Gene denotes monocyte chemoattractant protein-1 Gene:6347
447 10612-10616 Gene denotes MCP1 Gene:6347
448 10819-10823 Gene denotes IL-8 Gene:20309
449 10841-10845 Gene denotes MCP1 Gene:20296
450 10960-10964 Gene denotes MCP1 Gene:20296
451 10409-10427 Species denotes SARS-coronaviruses Tax:694009
452 10673-10694 Species denotes Japanese encephalitis Tax:11072
453 10695-10700 Species denotes mouse Tax:10090
454 11512-11522 Species denotes SARS-CoV-2 Tax:2697049
455 11713-11720 Species denotes patient Tax:9606
456 11812-11822 Species denotes SARS-CoV-2 Tax:2697049
457 10645-10667 Disease denotes coronavirus infections MESH:D018352
458 10724-10739 Disease denotes viral infection MESH:D001102
459 11252-11271 Disease denotes cortical irritation MESH:D001523
460 11290-11298 Disease denotes seizures MESH:D012640
461 11310-11318 Disease denotes COVID-19 MESH:C000657245
462 11319-11328 Disease denotes infection MESH:D007239
463 11382-11394 Disease denotes inflammation MESH:D007249
464 11418-11427 Disease denotes infection MESH:D007239
465 11483-11495 Disease denotes coagulopathy MESH:D001778
476 12110-12118 Species denotes patients Tax:9606
477 12500-12510 Species denotes SARS-CoV-2 Tax:2697049
478 12092-12100 Disease denotes COVID-19 MESH:C000657245
479 12131-12140 Disease denotes infection MESH:D007239
480 12182-12190 Disease denotes seizures MESH:D012640
481 12201-12215 Disease denotes encephalopathy MESH:D001927
482 12312-12320 Disease denotes seizures MESH:D012640
483 12334-12363 Disease denotes convulsive status epilepticus MESH:D013226
484 12382-12390 Disease denotes seizures MESH:D012640
485 12407-12427 Disease denotes SARS-CoV-2 infection MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T12 465-487 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T13 489-492 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T14 890-896 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T15 999-1004 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T16 1261-1280 Body_part denotes corticospinal tract http://purl.org/sig/ont/fma/fma265580
T17 1564-1569 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T18 2129-2134 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T19 2336-2342 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T20 2368-2386 Body_part denotes left bundle branch http://purl.org/sig/ont/fma/fma9487
T21 2510-2531 Body_part denotes right lower extremity http://purl.org/sig/ont/fma/fma7187
T22 2727-2739 Body_part denotes neutrophilic http://purl.org/sig/ont/fma/fma62860
T23 2761-2766 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T24 2866-2872 Body_part denotes tendon http://purl.org/sig/ont/fma/fma9721
T25 2971-2976 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T26 3035-3040 Body_part denotes spine http://purl.org/sig/ont/fma/fma13478
T27 3547-3552 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T28 3648-3653 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T29 3678-3682 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T30 3795-3815 Body_part denotes left upper extremity http://purl.org/sig/ont/fma/fma7186
T31 4298-4301 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T32 4323-4328 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T33 4333-4347 Body_part denotes cervical spine http://purl.org/sig/ont/fma/fma24138
T34 4406-4418 Body_part denotes white matter http://purl.org/sig/ont/fma/fma83929
T35 4473-4482 Body_part denotes meningeal http://purl.org/sig/ont/fma/fma231572
T36 5129-5136 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T37 5248-5264 Body_part denotes White blood cell http://purl.org/sig/ont/fma/fma62852
T38 5260-5264 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T39 5319-5327 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T40 5597-5603 Body_part denotes vertex http://purl.org/sig/ont/fma/fma46484
T41 5662-5670 Body_part denotes left arm http://purl.org/sig/ont/fma/fma24896
T42 5814-5819 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T43 5839-5845 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T44 5946-5952 Body_part denotes mental http://purl.org/sig/ont/fma/fma264279
T45 6105-6110 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T46 6125-6129 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T47 6262-6272 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T48 6448-6454 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T49 6463-6468 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T50 6547-6554 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T51 6837-6843 Body_part denotes eyelid http://purl.org/sig/ont/fma/fma54437
T52 7195-7200 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T53 7254-7266 Body_part denotes white matter http://purl.org/sig/ont/fma/fma83929
T54 7379-7384 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T55 7418-7435 Body_part denotes cardiac pacemaker http://purl.org/sig/ont/fma/fma9477
T56 7520-7526 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T57 8858-8861 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T58 9073-9083 Body_part denotes astrocytes http://purl.org/sig/ont/fma/fma54537
T59 9088-9097 Body_part denotes microglia http://purl.org/sig/ont/fma/fma68923
T60 9101-9112 Body_part denotes neural cell http://purl.org/sig/ont/fma/fma70333
T61 9108-9112 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T62 9152-9155 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T63 9176-9181 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T64 9304-9307 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T65 9375-9380 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T66 9381-9387 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T67 9509-9528 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T68 9530-9533 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T69 9937-9940 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T70 10035-10040 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T71 10041-10046 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T72 10266-10272 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T73 10301-10305 Body_part denotes glia http://purl.org/sig/ont/fma/fma54541
T74 10481-10490 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T75 10520-10525 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T76 10552-10565 Body_part denotes interleukin-8 http://purl.org/sig/ont/fma/fma264827
T77 10576-10584 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T78 10601-10608 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T79 10720-10723 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T80 10748-10757 Body_part denotes astrocyte http://purl.org/sig/ont/fma/fma54537
T81 10762-10771 Body_part denotes microglia http://purl.org/sig/ont/fma/fma68923
T82 10831-10834 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T83 10904-10907 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T84 10908-10913 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T85 10924-10934 Body_part denotes astrocytes http://purl.org/sig/ont/fma/fma54537
T86 10936-10943 Body_part denotes neurons http://purl.org/sig/ont/fma/fma54527
T87 10949-10958 Body_part denotes microglia http://purl.org/sig/ont/fma/fma68923
T88 11028-11033 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T89 11034-11039 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T90 11088-11093 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T91 11101-11110 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T92 11130-11135 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T93 11136-11141 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T94 11339-11358 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T95 11660-11679 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T96 11795-11798 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T97 12526-12531 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T98 12532-12537 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T99 12589-12597 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T13 465-487 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T14 473-487 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T15 489-492 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T16 999-1004 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T17 1261-1280 Body_part denotes corticospinal tract http://purl.obolibrary.org/obo/UBERON_0002707
T18 1564-1569 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T19 2129-2134 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T20 2336-2342 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T21 2795-2800 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T22 2866-2872 Body_part denotes tendon http://purl.obolibrary.org/obo/UBERON_0000043
T23 2971-2976 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T24 3547-3552 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T25 3648-3653 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T26 3678-3682 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T27 4323-4328 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T28 4406-4418 Body_part denotes white matter http://purl.obolibrary.org/obo/UBERON_0002316
T29 4498-4510 Body_part denotes venous sinus http://purl.obolibrary.org/obo/UBERON_0006615
T30 5254-5259 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T31 5667-5670 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T32 5814-5819 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T33 5839-5845 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T34 6105-6110 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T35 6125-6129 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T36 6448-6454 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T37 6463-6468 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T38 6837-6843 Body_part denotes eyelid http://purl.obolibrary.org/obo/UBERON_0001711
T39 7195-7200 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T40 7254-7266 Body_part denotes white matter http://purl.obolibrary.org/obo/UBERON_0002316
T41 7379-7384 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T42 7445-7451 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T43 7520-7526 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T44 8858-8861 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T45 9176-9181 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T46 9304-9307 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T47 9375-9380 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T48 9381-9387 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T49 9509-9528 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359
T50 9937-9940 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T51 10035-10054 Body_part denotes blood–brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T52 10035-10040 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T53 10041-10046 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T54 10266-10272 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T55 10520-10525 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T56 10720-10723 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T57 10904-10907 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T58 11028-11047 Body_part denotes blood–brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T59 11028-11033 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T60 11034-11039 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T61 11130-11149 Body_part denotes blood–brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T62 11130-11135 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T63 11136-11141 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T64 11339-11358 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359
T65 11660-11679 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359
T66 12526-12545 Body_part denotes blood–brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T67 12526-12531 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T68 12532-12537 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T26 13-60 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T27 62-70 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 235-243 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 257-281 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T30 283-291 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 688-696 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 749-757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 781-797 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T34 830-853 Disease denotes cerebrovascular disease http://purl.obolibrary.org/obo/MONDO_0011057
T35 861-875 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T36 993-1012 Disease denotes multi-organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T37 1074-1088 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T38 1242-1256 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T39 1431-1445 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T40 1505-1513 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 1564-1576 Disease denotes brain injury http://purl.obolibrary.org/obo/MONDO_0043510
T42 1570-1576 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T43 1580-1588 Disease denotes epilepsy http://purl.obolibrary.org/obo/MONDO_0005027
T44 1664-1672 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 1675-1684 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 1914-1922 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 2062-2076 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T48 2220-2228 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 2290-2296 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T50 2314-2326 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T51 2328-2350 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T52 2336-2350 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T54 2352-2366 Disease denotes hyperlipidemia http://purl.obolibrary.org/obo/MONDO_0021187
T55 2368-2392 Disease denotes left bundle branch block http://purl.obolibrary.org/obo/MONDO_0000991
T56 2373-2392 Disease denotes bundle branch block http://purl.obolibrary.org/obo/MONDO_0007240
T57 2576-2590 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T58 2658-2671 Disease denotes radiculopathy http://purl.obolibrary.org/obo/MONDO_0002959
T59 3053-3069 Disease denotes epidural abscess http://purl.obolibrary.org/obo/MONDO_0005752
T60 3062-3069 Disease denotes abscess http://purl.obolibrary.org/obo/MONDO_0005227
T61 3201-3206 Disease denotes Wound http://purl.obolibrary.org/obo/MONDO_0021178
T62 3300-3302 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T63 3359-3378 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T64 3846-3860 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T65 4511-4521 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T66 4622-4631 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T67 4843-4851 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 4905-4913 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 5735-5772 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T70 5755-5772 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T71 5774-5795 Disease denotes venous thromboembolic http://purl.obolibrary.org/obo/MONDO_0005399
T72 5805-5825 Disease denotes complete heart block http://purl.obolibrary.org/obo/MONDO_0000468
T73 5831-5853 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T74 5839-5853 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T76 6078-6097 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T77 6158-6169 Disease denotes pneumonitis http://purl.obolibrary.org/obo/MONDO_0043905
T78 6225-6236 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T79 6286-6298 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T80 6413-6429 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T81 6442-6461 Disease denotes acute kidney injury http://purl.obolibrary.org/obo/MONDO_0002492
T82 6455-6461 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T83 6666-6674 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 7048-7066 Disease denotes status epilepticus http://purl.obolibrary.org/obo/MONDO_0002125
T85 7527-7533 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T86 7597-7609 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T87 7964-7968 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T88 8132-8140 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T89 8258-8266 Disease denotes delirium http://purl.obolibrary.org/obo/MONDO_0045057
T90 8340-8350 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T91 8364-8372 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T92 8441-8449 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T93 8576-8599 Disease denotes cerebrovascular disease http://purl.obolibrary.org/obo/MONDO_0011057
T94 8605-8614 Disease denotes neuralgia http://purl.obolibrary.org/obo/MONDO_0021667
T95 8677-8685 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T96 8688-8697 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T97 8820-8838 Disease denotes status epilepticus http://purl.obolibrary.org/obo/MONDO_0002125
T98 8879-8887 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 8986-8994 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 8997-9006 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T101 9278-9286 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 9289-9298 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 9328-9332 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T104 9454-9458 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T105 9610-9618 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 9907-9923 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T107 9992-10000 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T108 10141-10156 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T109 10201-10209 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T110 10359-10380 Disease denotes neurological diseases http://purl.obolibrary.org/obo/MONDO_0005071
T111 10409-10413 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T112 10657-10670 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T113 10673-10694 Disease denotes Japanese encephalitis http://purl.obolibrary.org/obo/MONDO_0019209
T114 10682-10694 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T115 10724-10739 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T116 10730-10739 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T117 11310-11318 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T118 11319-11328 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T119 11382-11394 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T120 11418-11427 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T121 11483-11495 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T122 11512-11520 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T123 11812-11820 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 12092-12100 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 12131-12140 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T126 12201-12215 Disease denotes encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T127 12345-12363 Disease denotes status epilepticus http://purl.obolibrary.org/obo/MONDO_0002125
T128 12407-12415 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 12418-12427 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T130 12500-12508 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T27 145-146 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 313-325 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T29 446-449 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T30 465-487 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T31 465-487 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T32 465-487 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T33 489-492 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T34 489-492 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T35 489-492 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T36 881-896 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T37 881-896 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T38 881-896 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T39 999-1004 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T40 1293-1294 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 1495-1496 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T42 1564-1569 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T43 1564-1569 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T44 1787-1788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 2094-2102 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T46 2129-2134 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T47 2129-2134 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T48 2247-2248 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T49 2261-2265 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T50 2261-2265 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T51 2336-2342 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T52 2336-2342 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T53 2336-2342 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T54 2522-2531 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremity
T55 2621-2623 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T56 2761-2766 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T57 2780-2781 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 2866-2872 http://www.ebi.ac.uk/cellline#tendon denotes tendon
T59 2866-2872 http://www.ebi.ac.uk/efo/EFO_0000952 denotes tendon
T60 2928-2929 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T61 2971-2976 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T62 2971-2976 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T63 3081-3083 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T64 3547-3552 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T65 3648-3653 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T66 3678-3682 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T67 3678-3682 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T68 3696-3697 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 3725-3726 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T70 3806-3815 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremity
T71 3823-3831 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T72 4202-4210 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T73 4323-4328 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T74 4323-4328 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T75 4527-4529 http://purl.obolibrary.org/obo/CLO_0002131 denotes C5
T76 4530-4532 http://purl.obolibrary.org/obo/CLO_0002140 denotes C6
T77 4530-4532 http://purl.obolibrary.org/obo/CLO_0051387 denotes C6
T78 4530-4532 http://purl.obolibrary.org/obo/CLO_0051684 denotes C6
T79 4530-4532 http://purl.obolibrary.org/obo/CLO_0051685 denotes C6
T80 4530-4532 http://purl.obolibrary.org/obo/CLO_0051686 denotes C6
T81 4766-4767 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 4831-4838 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T83 4914-4925 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing was
T84 5254-5259 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T85 5260-5264 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T86 5383-5384 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 5446-5447 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 5667-5670 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T89 5717-5721 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T90 5717-5721 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T91 5814-5819 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T92 5814-5819 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T93 5814-5819 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T94 5814-5819 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T95 5839-5845 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T96 5839-5845 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T97 5839-5845 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T98 5897-5901 http://purl.obolibrary.org/obo/CLO_0001550 denotes a 10
T99 6103-6104 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 6105-6110 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T101 6125-6129 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T102 6125-6129 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T103 6431-6434 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T104 6448-6454 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T105 6448-6454 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T106 6448-6454 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T107 6463-6468 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T108 6463-6468 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T109 6603-6604 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T110 6657-6661 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T111 7177-7178 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T112 7195-7200 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T113 7195-7200 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T114 7379-7384 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T115 7379-7384 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T116 7445-7451 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T117 7520-7526 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T118 7520-7526 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T119 7520-7526 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T120 7535-7536 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T121 7846-7847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T122 7885-7896 http://purl.obolibrary.org/obo/UBERON_0001353 denotes posteriorly
T123 7898-7899 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T124 8041-8046 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T125 8058-8065 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T126 8651-8652 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 8856-8857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 8858-8861 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T129 8858-8861 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T130 8858-8861 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T131 9008-9013 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T132 9067-9072 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T133 9073-9083 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocytes
T134 9088-9097 http://purl.obolibrary.org/obo/CL_0000129 denotes microglia
T135 9108-9112 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T136 9159-9160 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 9170-9175 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T138 9176-9181 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T139 9176-9181 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T140 9261-9262 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T141 9304-9307 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T142 9304-9307 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T143 9304-9307 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T144 9360-9365 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 9373-9374 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 9375-9380 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T147 9375-9380 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T148 9430-9431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T149 9465-9468 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T150 9703-9708 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T151 9830-9831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 9867-9872 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T153 9883-9884 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T154 9937-9940 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T155 9937-9940 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T156 9937-9940 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T157 10035-10040 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T158 10035-10040 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T159 10041-10046 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T160 10041-10046 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T161 10060-10065 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T162 10139-10140 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T163 10500-10506 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T164 10520-10525 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T165 10520-10525 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T166 10567-10570 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL8
T167 10576-10584 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T168 10623-10625 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T169 10628-10629 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T170 10671-10672 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T171 10695-10700 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T172 10720-10723 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T173 10720-10723 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T174 10720-10723 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T175 10748-10757 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocyte
T176 10762-10771 http://purl.obolibrary.org/obo/CL_0000129 denotes microglia
T177 10819-10823 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T178 10904-10907 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T179 10904-10907 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T180 10904-10907 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T181 10908-10913 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T182 10924-10934 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocytes
T183 10949-10958 http://purl.obolibrary.org/obo/CL_0000129 denotes microglia
T184 11028-11033 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T185 11028-11033 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T186 11034-11039 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T187 11034-11039 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T188 11088-11093 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T189 11101-11110 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T190 11130-11135 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T191 11130-11135 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T192 11136-11141 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T193 11136-11141 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T194 11151-11153 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T195 11179-11180 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 11521-11525 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2, a
T197 11620-11621 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T198 11739-11740 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 11793-11794 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T200 11803-11807 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T201 12473-12474 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 12526-12531 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T203 12526-12531 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T204 12532-12537 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T205 12532-12537 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T5 2261-2265 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T6 3161-3171 Chemical denotes vancomycin http://purl.obolibrary.org/obo/CHEBI_28001|http://purl.obolibrary.org/obo/CHEBI_76842
T8 3176-3188 Chemical denotes piperacillin http://purl.obolibrary.org/obo/CHEBI_8232
T9 3189-3199 Chemical denotes tazobactam http://purl.obolibrary.org/obo/CHEBI_9421
T10 3253-3263 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T11 4006-4009 Chemical denotes EEG http://purl.obolibrary.org/obo/CHEBI_73494
T12 4129-4142 Chemical denotes Levetiracetam http://purl.obolibrary.org/obo/CHEBI_6437
T13 4257-4267 Chemical denotes Vancomycin http://purl.obolibrary.org/obo/CHEBI_28001
T14 4269-4278 Chemical denotes Meropenem http://purl.obolibrary.org/obo/CHEBI_43968
T15 5129-5136 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T16 5225-5238 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T17 5717-5721 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T18 6371-6374 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088
T19 6469-6473 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T20 6474-6482 Chemical denotes nitrogen http://purl.obolibrary.org/obo/CHEBI_25555
T21 6499-6509 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T22 6547-6554 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T23 6765-6768 Chemical denotes EEG http://purl.obolibrary.org/obo/CHEBI_73494
T24 6906-6909 Chemical denotes EEG http://purl.obolibrary.org/obo/CHEBI_73494
T25 7162-7175 Chemical denotes levetiracetam http://purl.obolibrary.org/obo/CHEBI_6437
T26 7620-7623 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088
T27 8012-8017 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T28 8150-8155 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T29 10567-10570 Chemical denotes IL8 http://purl.obolibrary.org/obo/CHEBI_138181
T30 10601-10608 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T31 10819-10821 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T4 3487-3495 http://purl.obolibrary.org/obo/GO_0035810 denotes diuresis
T5 10534-10543 http://purl.obolibrary.org/obo/GO_0009056 denotes breakdown
T6 10724-10739 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T7 11382-11394 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T8 12546-12555 http://purl.obolibrary.org/obo/GO_0009056 denotes breakdown

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T20 855-875 Phenotype denotes acute encephalopathy http://purl.obolibrary.org/obo/HP_0006846
T21 1074-1088 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T22 1126-1146 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T23 1242-1256 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T24 1431-1445 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T25 1451-1459 Phenotype denotes Seizures http://purl.obolibrary.org/obo/HP_0001250
T26 1580-1588 Phenotype denotes epilepsy http://purl.obolibrary.org/obo/HP_0001250
T27 2056-2076 Phenotype denotes acute encephalopathy http://purl.obolibrary.org/obo/HP_0006846
T28 2081-2088 Phenotype denotes seizure http://purl.obolibrary.org/obo/HP_0001250
T29 2176-2196 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T30 2290-2296 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T31 2314-2326 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T32 2328-2350 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T33 2352-2366 Phenotype denotes hyperlipidemia http://purl.obolibrary.org/obo/HP_0003077
T34 2368-2392 Phenotype denotes left bundle branch block http://purl.obolibrary.org/obo/HP_0011713
T35 2532-2536 Phenotype denotes pain http://purl.obolibrary.org/obo/HP_0012531
T36 2538-2543 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T37 2576-2590 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T38 2740-2752 Phenotype denotes leukocytosis http://purl.obolibrary.org/obo/HP_0001974
T39 2790-2794 Phenotype denotes coma http://purl.obolibrary.org/obo/HP_0001259
T40 3062-3069 Phenotype denotes abscess http://purl.obolibrary.org/obo/HP_0025615
T41 3286-3298 Phenotype denotes leukocytosis http://purl.obolibrary.org/obo/HP_0001974
T42 3359-3378 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T43 3678-3694 Phenotype denotes lung infiltrates http://purl.obolibrary.org/obo/HP_0002113
T44 3846-3860 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T45 3926-3936 Phenotype denotes drowsiness http://purl.obolibrary.org/obo/HP_0002329
T46 4027-4041 Phenotype denotes focal seizures http://purl.obolibrary.org/obo/HP_0007359
T47 4194-4201 Phenotype denotes seizure http://purl.obolibrary.org/obo/HP_0001250
T48 4406-4435 Phenotype denotes white matter hyperintensities http://purl.obolibrary.org/obo/HP_0030890
T49 5735-5772 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T50 5781-5803 Phenotype denotes thromboembolic disease http://purl.obolibrary.org/obo/HP_0001907
T51 5805-5825 Phenotype denotes complete heart block http://purl.obolibrary.org/obo/HP_0001709
T52 5831-5853 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T53 5929-5936 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T54 5965-5985 Phenotype denotes generalized weakness http://purl.obolibrary.org/obo/HP_0003324
T55 6078-6097 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T56 6125-6141 Phenotype denotes lung infiltrates http://purl.obolibrary.org/obo/HP_0002113
T57 6225-6236 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T58 6286-6298 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T59 6383-6399 Phenotype denotes elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T60 6413-6429 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T61 6442-6461 Phenotype denotes acute kidney injury http://purl.obolibrary.org/obo/HP_0001919
T62 6855-6864 Phenotype denotes twitching http://purl.obolibrary.org/obo/HP_0010546
T63 6910-6918 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250
T64 7048-7066 Phenotype denotes status epilepticus http://purl.obolibrary.org/obo/HP_0002133
T65 7084-7092 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250
T66 7114-7121 Phenotype denotes Seizure http://purl.obolibrary.org/obo/HP_0001250
T67 7597-7609 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T68 8258-8266 Phenotype denotes delirium http://purl.obolibrary.org/obo/HP_0031258
T69 8268-8277 Phenotype denotes dizziness http://purl.obolibrary.org/obo/HP_0002321
T70 8283-8292 Phenotype denotes headaches http://purl.obolibrary.org/obo/HP_0002315
T71 8531-8539 Phenotype denotes headache http://purl.obolibrary.org/obo/HP_0002315
T72 8541-8550 Phenotype denotes dizziness http://purl.obolibrary.org/obo/HP_0002321
T73 8605-8614 Phenotype denotes neuralgia http://purl.obolibrary.org/obo/HP_0033345
T74 8621-8629 Phenotype denotes Seizures http://purl.obolibrary.org/obo/HP_0001250
T75 8746-8760 Phenotype denotes focal seizures http://purl.obolibrary.org/obo/HP_0007359
T76 8805-8838 Phenotype denotes non-convulsive status epilepticus http://purl.obolibrary.org/obo/HP_0031475
T77 8840-8848 Phenotype denotes Seizures http://purl.obolibrary.org/obo/HP_0001250
T78 9788-9808 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T79 10333-10341 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250
T80 10682-10694 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T81 11290-11298 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250
T82 11483-11495 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T83 12124-12140 Phenotype denotes severe infection http://purl.obolibrary.org/obo/HP_0032169
T84 12182-12190 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250
T85 12201-12215 Phenotype denotes encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T86 12300-12320 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T87 12330-12363 Phenotype denotes non-convulsive status epilepticus http://purl.obolibrary.org/obo/HP_0031475
T88 12382-12390 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T26 0-12 Sentence denotes Introduction
T27 13-184 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged first in Wuhan, China, in 2019 and spread rapidly worldwide as a pandemic of the twenty-first century.
T28 185-330 Sentence denotes The symptoms and disease manifestations caused by SARS-CoV-2 were named Coronavirus disease 2019 (COVID-19) by the World Health Organization [1].
T29 331-562 Sentence denotes The neurological manifestations of this disease are not well known, and there is growing evidence that the disease has effects on the central nervous system (CNS) as detailed in retrospective reports from several centers worldwide.
T30 563-709 Sentence denotes An initial retrospective case series from Wuhan, China, showed that neurological manifestations are present in patients with COVID-19 disease [2].
T31 710-906 Sentence denotes In that series, 45.5% of patients with COVID-19 disease who had severe systemic disease burden also suffered from acute cerebrovascular disease, acute encephalopathy, and skeletal muscle symptoms.
T32 907-1013 Sentence denotes These patients also had higher levels of inflammatory markers and greater evidence of multi-organ failure.
T33 1014-1147 Sentence denotes However, the study did not elucidate how many patients with encephalopathy were monitored and treated for acute symptomatic seizures.
T34 1148-1287 Sentence denotes Another series of patients were reported in Strasbourg, France, with neurological features of encephalopathy and corticospinal tract signs.
T35 1288-1450 Sentence denotes Only a small proportion of the patients (8 out of 64) had electroencephalography performed, which demonstrated diffuse slowing consistent with encephalopathy [3].
T36 1451-1589 Sentence denotes Seizures have not been directly reported as a part of COVID-19 disease outside of patients with previously known brain injury or epilepsy.
T37 1590-1847 Sentence denotes There are several barriers to electrographically monitoring patients with SARS-CoV-2 infection such as prone positioning for respiratory compromise as well as the contamination risk which obviates a need for minimizing procedures in this patient population.
T38 1848-1972 Sentence denotes Neurointensivists and neurologists are often consulted for severe COVID-19 patients that present with neurological features.
T39 1973-2237 Sentence denotes In this report, we describe two patients who were electrographically monitored for acute encephalopathy and seizure-like activity, in the setting of normal brain imaging and who were found to have acute symptomatic seizures associated with severe COVID-19 disease.
T40 2239-2246 Sentence denotes Case #1
T41 2247-2591 Sentence denotes A 76-year-old male with history of chronic asthma on benralizumab, hypertension, chronic kidney disease, hyperlipidemia, left bundle branch block, diastolic dysfunction, and cervical fusion presented to the emergency department with the chief complaint of severe right lower extremity pain, fever (102.5 °F on presentation), and encephalopathy.
T42 2592-2701 Sentence denotes He was status post recent L3-S1 laminectomy for acute lumbosacral radiculopathy 5 days prior to presentation.
T43 2702-2772 Sentence denotes Laboratory workup showed neutrophilic leukocytosis (17,200 cells/mm3).
T44 2773-2927 Sentence denotes He had a Glasgow coma scale of 14, was oriented to name only, and exhibited exaggerated deep tendon reflexes but had no other focal neurological deficits.
T45 2928-2994 Sentence denotes A computerized tomography (CT) scan of the brain was unremarkable.
T46 2995-3084 Sentence denotes Magnetic resonance imaging (MRI) of the spine revealed an epidural abscess between L4-S1.
T47 3085-3200 Sentence denotes Surgical drainage was performed, and the patient was started empirically on vancomycin and piperacillin–tazobactam.
T48 3201-3244 Sentence denotes Wound cultures grew Pseudomonas aeruginosa.
T49 3245-3441 Sentence denotes Despite antibiotic therapy, and improved leukocytosis, he continued to have high-grade fevers and acute hypoxemic respiratory failure requiring intensive care unit transfer on postoperative day 1.
T50 3442-3640 Sentence denotes He was initially managed conservatively with diuresis, preload, and afterload optimization; however, his chest X-ray rapidly progressed to bilateral interstitial and airspace opacification (Fig. 1).
T51 3641-3727 Sentence denotes Fig. 1 Chest X-ray showing bilateral lung infiltrates (a) compared to his baseline (b)
T52 3728-3970 Sentence denotes On postoperative day two, the patient suffered several episodes of left upper extremity clonic activity and worsening encephalopathy with decline in level of consciousness as evidenced by increased drowsiness and inability to follow commands.
T53 3971-4128 Sentence denotes Continuous electroencephalography (EEG) confirmed three focal seizures lasting approximately 30 s each arising from the right centroparietal region (Fig. 2).
T54 4129-4220 Sentence denotes Levetiracetam was initiated and both clinical and electrographic seizure activity subsided.
T55 4221-4311 Sentence denotes Antibiotic regimen was broadened to Vancomycin, Meropenem, and Acyclovir for CSF coverage.
T56 4312-4560 Sentence denotes MRI of the brain and cervical spine with and without contrast was remarkable only for chronic white matter hyperintensities, without acute intracranial lesions, meningeal enhancement or venous sinus thrombosis, and C5–C6 myelomalacia, respectively.
T57 4561-4647 Sentence denotes Lumbar puncture was not performed due to the risk of seeding infection into neuroaxis.
T58 4648-4972 Sentence denotes Given persistent high-grade fevers, worsening respiratory status requiring intubation, and recent possible exposures, a respiratory viral panel was sent in addition to separate rapid testing for COVID-19 polymerase chain reaction on postoperative day 4 and COVID-19 testing was confirmed as positive twenty-four hours later.
T59 4973-5117 Sentence denotes His fibrinogen level was elevated at 631 mg/dL (normal range 200–400 mg/dL) and continued to increase to over 860 mg/dL over the following days.
T60 5118-5247 Sentence denotes C-reactive protein increased from 1.7 mg/dL on prior admission to 27.3 mg/dL and remained elevated despite antimicrobial therapy.
T61 5248-5350 Sentence denotes White blood cell count steadily improved over his hospitalization, and platelet count remained stable.
T62 5351-5512 Sentence denotes Our patient ultimately received a tracheostomy and after 30 days of ICU stay was discharged to a long-term acute care hospital for further ventilator management.
T63 5513-5543 Sentence denotes Fig. 2 Electroencephalography.
T64 5544-5692 Sentence denotes Rhythmic discharges noted in the right frontocentral/vertex region (red box) corresponding to clonic movements of the left arm (Color figure online)
T65 5694-5701 Sentence denotes Case #2
T66 5702-5986 Sentence denotes An 82-year-old male patient with chronic obstructive pulmonary disease, venous thromboembolic disease, complete heart block, and chronic kidney disease presented to the emergency department with a 10-day history of progressive dyspnea, altered mental status, and generalized weakness.
T67 5987-6040 Sentence denotes He was found to be hypoxic, febrile, and tachycardic.
T68 6041-6170 Sentence denotes He was intubated for acute hypoxemic respiratory failure with a chest X-ray showing lung infiltrates consistent with pneumonitis.
T69 6171-6602 Sentence denotes The patient’s laboratory results were significant for lymphopenia (WBC 3.26 k/μl, absolute lymphocyte count 0.70), coagulopathy (international normalised ratio (INR) 2.5, partial thromboplastin time (PTT) 53.9), elevated D-dimer (590 ng/mL), thrombocytopenia (132 k/μl), acute kidney injury (blood urea nitrogen (BUN) 47 mg/dL, creatinine 3.96 mg/dL), and elevated C-reactive protein initially 12.5 mg/L and increased to 26.2 mg/L.
T70 6603-6725 Sentence denotes A nasopharyngeal swab polymerase chain reaction (PCR) test for COVID-19 was sent on admission and was positive 24 h later.
T71 6726-6896 Sentence denotes Continuous video electroencephalogram (EEG) monitoring was ordered on day 5 of admission after events of right eyelid and facial twitching were observed by the care team.
T72 6897-7067 Sentence denotes Frequent EEG seizures were captured independently from the left more than right frontal–temporal regions (Fig. 3) which eventually progressed to focal status epilepticus.
T73 7068-7113 Sentence denotes The majority of seizures were non-convulsive.
T74 7114-7176 Sentence denotes Seizure frequency improved after treatment with levetiracetam.
T75 7177-7349 Sentence denotes A non-contrast CT-brain demonstrated hypodensities within the supratentorial white matter, consistent with mild microvascular disease but without acute intracranial lesion.
T76 7350-7436 Sentence denotes He was unable to have an MRI brain performed due to an incompatible cardiac pacemaker.
T77 7437-7534 Sentence denotes Further vessel imaging was unable to be performed due to patients acute on chronic kidney injury.
T78 7535-7630 Sentence denotes A lumbar puncture was unable to be performed due to worsening coagulopathy (INR 3.8, PTT 73.5).
T79 7631-7757 Sentence denotes Patient remained on the ventilator, and after 20 days of ICU stay, the family opted for withdrawal of life-sustaining support.
T80 7758-7788 Sentence denotes Fig. 3 Electroencephalography.
T81 7789-7947 Sentence denotes Rhythmic discharges evolving in the left frontotemporal (a) region and spreading anteriorly and posteriorly (b) corresponding to right facial clonic movements
T82 7949-7959 Sentence denotes Discussion
T83 7960-8143 Sentence denotes The SARS-Coronavirus-2 belongs to the β-coronavirus group which includes several human pathogenic viruses including middle east respiratory syndrome (MERS) coronavirus and SARS-CoV-1.
T84 8144-8214 Sentence denotes These group of coronaviruses are associated with respiratory symptoms.
T85 8215-8388 Sentence denotes Additional neurological symptoms including delirium, dizziness, and headaches have also been reported with other coronavirus infections prior to the SARS-CoV-2 outbreak [4].
T86 8389-8620 Sentence denotes The case series of patients from Wuhan, China, with COVID-19 disease, included both central and peripheral neurological manifestations (i.e., headache, dizziness, impaired consciousness, cerebrovascular disease, and neuralgia) [2].
T87 8621-8698 Sentence denotes Seizures were not reported as a direct manifestation of SARS-CoV-2 infection.
T88 8699-8839 Sentence denotes The patients described in our series developed focal seizures and, in the second case, even progressed to non-convulsive status epilepticus.
T89 8840-8896 Sentence denotes Seizures may be a CNS manifestation of COVID-19 disease.
T90 8897-9007 Sentence denotes Further investigations are needed to elucidate the mechanism of neurological symptoms in SARS-CoV-2 infection.
T91 9008-9260 Sentence denotes Human coronaviruses (HCoV) have been established to infect human astrocytes and microglia in neural cell cultures as well as detection of viral RNA in a study of human brain autopsy samples supporting their neurotropic and neuroinvasive properties [5].
T92 9261-9401 Sentence denotes A case report of SARS-CoV-1 infection with CNS symptoms during the SARS epidemic also isolated the virus within a brain tissue specimen [6].
T93 9402-9781 Sentence denotes Although direct evidence of a neurotropic effect of SARS-Cov-2 has not been reported as yet through either cerebrospinal fluid (CSF) or autopsy studies, the presence of neurological symptoms in patients with COVID-19 disease during this current pandemic, and the similarity between the two strains of human coronaviruses (CoV-1 and CoV-2), makes this mechanism highly suggestive.
T94 9782-10009 Sentence denotes Acute symptomatic seizures may be the result of a possible neurotropic effect of the virus or can be a marker of severity of systemic disease itself since CNS symptoms were found mainly in patients with severe COVID-19 disease.
T95 10010-10163 Sentence denotes After penetration of the blood–brain barrier, the virus can slow the cerebral microcirculation, possibly through the creation of a hypercoagulable state.
T96 10164-10277 Sentence denotes This allows increased interaction of SARS-CoV-2 with the endothelial receptors and receptors on glial tissue [7].
T97 10278-10388 Sentence denotes The interaction at the glia may predispose patients to seizures as seen in other neurological diseases [8, 9].
T98 10389-10627 Sentence denotes Previous studies of SARS-coronaviruses have described the proliferation of pro-inflammatory cytokines that are active in promoting blood–barrier breakdown, namely interleukin-8 (IL8) and monocyte chemoattractant protein-1 (MCP1) [10, 11].
T99 10628-10840 Sentence denotes A description of coronavirus infections in a Japanese encephalitis mouse model demonstrated CNS viral infection induced astrocyte and microglia proliferation, leading to increased release of IL-8 in the CSF [10].
T100 10841-10959 Sentence denotes MCP1 is another pro-inflammatory mediator that is expressed in CNS cells including astrocytes, neurons, and microglia.
T101 10960-11155 Sentence denotes MCP1 may be up-regulated in conditions which target and degrade the blood–brain barrier and can recruit additional inflammatory cells as the monocytes migrate across the blood–brain barrier [11].
T102 11156-11329 Sentence denotes We hypothesize that as a result of the accumulation of inflammatory markers, there may be local cortical irritation that precipitates seizures related to COVID-19 infection.
T103 11330-11619 Sentence denotes Although cerebrospinal fluid may contain markers of inflammation, the treatment of this infection is largely supportive, and with the additional risk of coagulopathy precipitated by SARS-CoV-2, a lumbar puncture may not be justifiable unless there is an alternative diagnosis to be sought.
T104 11620-11858 Sentence denotes A limitation of our case series is that cerebrospinal fluid was unable to be obtained due to patient factors that made a lumbar puncture relatively contraindicated and that a CSF-PCR test for SARS-CoV-2 was not yet commercially available.
T105 11859-11971 Sentence denotes As this disease continues to spread, we will continue to learn about its direct and/or indirect epileptogenesis.
T106 11973-11984 Sentence denotes Conclusions
T107 11985-12364 Sentence denotes Although there are concerns regarding decreasing transmission risk by limiting healthcare interventions in COVID-19 disease, patients with severe infection who demonstrate either clinical signs of seizures or severe encephalopathy may benefit from continuous electroencephalography monitoring to diagnose and treat symptomatic seizures and also non-convulsive status epilepticus.
T108 12365-12608 Sentence denotes The mechanism of seizures precipitated by SARS-CoV-2 infection appears to be multifactorial and may involve a possible neurotropism of SARS-CoV-2 in addition to blood–brain barrier breakdown precipitated by pro-inflammatory cytokine reactions.

2_test

Id Subject Object Predicate Lexical cue
32462412-32257431-75539777 327-328 32257431 denotes 1
32462412-32453517-75539778 1447-1448 32453517 denotes 3
32462412-10982334-75539779 9257-9258 10982334 denotes 5
32462412-16163626-75539780 9398-9399 16163626 denotes 6
32462412-32167747-75539781 10274-10275 32167747 denotes 7
32462412-18336559-75539782 10385-10386 18336559 denotes 9
32462412-28103598-75539783 10619-10621 28103598 denotes 10
32462412-24051980-75539784 10623-10625 24051980 denotes 11
32462412-28103598-75539785 10836-10838 28103598 denotes 10
32462412-24051980-75539786 11151-11153 24051980 denotes 11