PMC:7253232 / 81-2069
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 382-384 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T2 | 484-486 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T3 | 637-639 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T4 | 679-681 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T5 | 1378-1380 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T6 | 1457-1459 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
| T7 | 1863-1865 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 12 | 189-195 | Species | denotes | people | Tax:9606 |
| 13 | 889-896 | Species | denotes | patient | Tax:9606 |
| 14 | 328-333 | Chemical | denotes | water | MESH:D014867 |
| 15 | 372-380 | Chemical | denotes | nitrogen | MESH:D009584 |
| 16 | 382-384 | Chemical | denotes | LN | |
| 17 | 104-112 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 18 | 587-590 | Disease | denotes | IVF | MESH:C537182 |
| 19 | 981-988 | Disease | denotes | ovarian | MESH:D010049 |
| 22 | 1564-1574 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 23 | 1575-1583 | Species | denotes | patients | Tax:9606 |
| 25 | 1792-1802 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 459-466 | Body_part | denotes | embryos | http://purl.org/sig/ont/fma/fma296970 |
| T2 | 760-765 | Body_part | denotes | sperm | http://purl.org/sig/ont/fma/fma67338 |
| T3 | 767-774 | Body_part | denotes | oocytes | http://purl.org/sig/ont/fma/fma18644 |
| T4 | 779-786 | Body_part | denotes | embryos | http://purl.org/sig/ont/fma/fma296970 |
| T5 | 993-999 | Body_part | denotes | testis | http://purl.org/sig/ont/fma/fma7210 |
| T6 | 1000-1007 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T7 | 1611-1616 | Body_part | denotes | semen | http://purl.org/sig/ont/fma/fma62966 |
| T8 | 1883-1888 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T9 | 1893-1900 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 993-999 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
| T2 | 1611-1616 | Body_part | denotes | semen | http://purl.obolibrary.org/obo/UBERON_0001968 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T2 | 104-112 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 382-384 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T4 | 484-486 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T5 | 637-639 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T6 | 679-681 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T7 | 1370-1377 | Disease | denotes | sterile | http://purl.obolibrary.org/obo/MONDO_0005047 |
| T8 | 1378-1380 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T9 | 1457-1459 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
| T10 | 1478-1485 | Disease | denotes | sterile | http://purl.obolibrary.org/obo/MONDO_0005047 |
| T11 | 1564-1572 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T12 | 1792-1800 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T13 | 1863-1865 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 0-1 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T3 | 23-26 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T4 | 61-73 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T5 | 212-217 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T6 | 291-292 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T7 | 293-298 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T8 | 302-303 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T9 | 414-417 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T10 | 459-466 | http://purl.obolibrary.org/obo/UBERON_0000922 | denotes | embryos |
| T11 | 520-521 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T12 | 625-630 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T13 | 779-786 | http://purl.obolibrary.org/obo/UBERON_0000922 | denotes | embryos |
| T14 | 855-860 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T15 | 993-999 | http://www.ebi.ac.uk/efo/EFO_0000984 | denotes | testis |
| T16 | 1009-1013 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 3, 4 |
| T17 | 1154-1159 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T18 | 1351-1358 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 5]. (2) |
| T19 | 1596-1601 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T20 | 1676-1677 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T21 | 1779-1786 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T22 | 1883-1888 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 328-333 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T2 | 372-380 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
| T3 | 382-384 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T5 | 484-486 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T7 | 637-639 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T9 | 679-681 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T11 | 1378-1380 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T13 | 1457-1459 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
| T15 | 1863-1865 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 567-574 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
| T2 | 1391-1398 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
| T3 | 1513-1520 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
| T4 | 1652-1659 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 0-113 | Sentence | denotes | A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. |
| T3 | 114-265 | Sentence | denotes | Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. |
| T4 | 266-386 | Sentence | denotes | According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). |
| T5 | 387-506 | Sentence | denotes | Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. |
| T6 | 507-596 | Sentence | denotes | This data is a cause for concern regarding the current cryo-storage practice in IVF labs. |
| T7 | 597-682 | Sentence | denotes | If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. |
| T8 | 683-1177 | Sentence | denotes | Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive. |
| T9 | 1178-1525 | Sentence | denotes | In order to overcome the above scenarios, several solutions may be applicable: (1) The use of closed system vitrification systems incorporating CBS straws or other systems [5]. (2) The use of sterile LN and vapor storage [6]. (3) Another option is the use of UV sterilization of LN [7] or the use of sterile liquid air for cooling and storage [8]. |
| T10 | 1526-1758 | Sentence | denotes | Finally, if it is true that 15–26% of SARS-CoV-2 patients present the virus in their semen [9], then washing, separation, and storage (quarantine) in a separate container or in special canister [8] should be done as safety measures. |
| T11 | 1759-1988 | Sentence | denotes | Until properties of viruses like SARS-CoV-2 are fully investigated with respect to the interaction with LN and reproductive cells and tissues, cautionary measures as those mentioned above should be taken under serious advisement. |