PMC:7253232 / 81-1258 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T1","span":{"begin":382,"end":384},"obj":"https://glytoucan.org/Structures/Glycans/G04616ST"},{"id":"T2","span":{"begin":484,"end":486},"obj":"https://glytoucan.org/Structures/Glycans/G04616ST"},{"id":"T3","span":{"begin":637,"end":639},"obj":"https://glytoucan.org/Structures/Glycans/G04616ST"},{"id":"T4","span":{"begin":679,"end":681},"obj":"https://glytoucan.org/Structures/Glycans/G04616ST"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PubTator","denotations":[{"id":"12","span":{"begin":189,"end":195},"obj":"Species"},{"id":"13","span":{"begin":889,"end":896},"obj":"Species"},{"id":"14","span":{"begin":328,"end":333},"obj":"Chemical"},{"id":"15","span":{"begin":372,"end":380},"obj":"Chemical"},{"id":"16","span":{"begin":382,"end":384},"obj":"Chemical"},{"id":"17","span":{"begin":104,"end":112},"obj":"Disease"},{"id":"18","span":{"begin":587,"end":590},"obj":"Disease"},{"id":"19","span":{"begin":981,"end":988},"obj":"Disease"}],"attributes":[{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"Tax:9606"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"Tax:9606"},{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"MESH:D014867"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"MESH:D009584"},{"id":"A17","pred":"tao:has_database_id","subj":"17","obj":"MESH:C000657245"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:C537182"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"MESH:D010049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":459,"end":466},"obj":"Body_part"},{"id":"T2","span":{"begin":760,"end":765},"obj":"Body_part"},{"id":"T3","span":{"begin":767,"end":774},"obj":"Body_part"},{"id":"T4","span":{"begin":779,"end":786},"obj":"Body_part"},{"id":"T5","span":{"begin":993,"end":999},"obj":"Body_part"},{"id":"T6","span":{"begin":1000,"end":1007},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma296970"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67338"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma18644"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma296970"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma7210"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":993,"end":999},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T2","span":{"begin":104,"end":112},"obj":"Disease"},{"id":"T3","span":{"begin":382,"end":384},"obj":"Disease"},{"id":"T4","span":{"begin":484,"end":486},"obj":"Disease"},{"id":"T5","span":{"begin":637,"end":639},"obj":"Disease"},{"id":"T6","span":{"begin":679,"end":681},"obj":"Disease"}],"attributes":[{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0002486"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0002486"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0002486"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0002486"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T2","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T3","span":{"begin":23,"end":26},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T4","span":{"begin":61,"end":73},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T5","span":{"begin":212,"end":217},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T6","span":{"begin":291,"end":292},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T7","span":{"begin":293,"end":298},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T8","span":{"begin":302,"end":303},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T9","span":{"begin":414,"end":417},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T10","span":{"begin":459,"end":466},"obj":"http://purl.obolibrary.org/obo/UBERON_0000922"},{"id":"T11","span":{"begin":520,"end":521},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":625,"end":630},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T13","span":{"begin":779,"end":786},"obj":"http://purl.obolibrary.org/obo/UBERON_0000922"},{"id":"T14","span":{"begin":855,"end":860},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T15","span":{"begin":993,"end":999},"obj":"http://www.ebi.ac.uk/efo/EFO_0000984"},{"id":"T16","span":{"begin":1009,"end":1013},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T17","span":{"begin":1154,"end":1159},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":328,"end":333},"obj":"Chemical"},{"id":"T2","span":{"begin":372,"end":380},"obj":"Chemical"},{"id":"T3","span":{"begin":382,"end":384},"obj":"Chemical"},{"id":"T5","span":{"begin":484,"end":486},"obj":"Chemical"},{"id":"T7","span":{"begin":637,"end":639},"obj":"Chemical"},{"id":"T9","span":{"begin":679,"end":681},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_25555"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_17571"},{"id":"A4","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_73529"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_17571"},{"id":"A6","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_73529"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17571"},{"id":"A8","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_73529"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_17571"},{"id":"A10","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_73529"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":567,"end":574},"obj":"http://purl.obolibrary.org/obo/GO_0051235"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}

{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":0,"end":113},"obj":"Sentence"},{"id":"T3","span":{"begin":114,"end":265},"obj":"Sentence"},{"id":"T4","span":{"begin":266,"end":386},"obj":"Sentence"},{"id":"T5","span":{"begin":387,"end":506},"obj":"Sentence"},{"id":"T6","span":{"begin":507,"end":596},"obj":"Sentence"},{"id":"T7","span":{"begin":597,"end":682},"obj":"Sentence"},{"id":"T8","span":{"begin":683,"end":1177},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. This data is a cause for concern regarding the current cryo-storage practice in IVF labs. If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive."}