
PMC:7253232
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 463-465 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T2 | 565-567 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T3 | 718-720 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T4 | 760-762 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T5 | 1459-1461 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T6 | 1538-1540 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
T7 | 1944-1946 | https://glytoucan.org/Structures/Glycans/G04616ST | denotes | LN |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
2 | 21-24 | Disease | denotes | IVF | MESH:C537182 |
3 | 62-70 | Disease | denotes | COVID-19 | MESH:C000657245 |
12 | 270-276 | Species | denotes | people | Tax:9606 |
13 | 970-977 | Species | denotes | patient | Tax:9606 |
14 | 409-414 | Chemical | denotes | water | MESH:D014867 |
15 | 453-461 | Chemical | denotes | nitrogen | MESH:D009584 |
16 | 463-465 | Chemical | denotes | LN | |
17 | 185-193 | Disease | denotes | COVID-19 | MESH:C000657245 |
18 | 668-671 | Disease | denotes | IVF | MESH:C537182 |
19 | 1062-1069 | Disease | denotes | ovarian | MESH:D010049 |
22 | 1645-1655 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
23 | 1656-1664 | Species | denotes | patients | Tax:9606 |
25 | 1873-1883 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 540-547 | Body_part | denotes | embryos | http://purl.org/sig/ont/fma/fma296970 |
T2 | 841-846 | Body_part | denotes | sperm | http://purl.org/sig/ont/fma/fma67338 |
T3 | 848-855 | Body_part | denotes | oocytes | http://purl.org/sig/ont/fma/fma18644 |
T4 | 860-867 | Body_part | denotes | embryos | http://purl.org/sig/ont/fma/fma296970 |
T5 | 1074-1080 | Body_part | denotes | testis | http://purl.org/sig/ont/fma/fma7210 |
T6 | 1081-1088 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T7 | 1692-1697 | Body_part | denotes | semen | http://purl.org/sig/ont/fma/fma62966 |
T8 | 1964-1969 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T9 | 1974-1981 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1074-1080 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
T2 | 1692-1697 | Body_part | denotes | semen | http://purl.obolibrary.org/obo/UBERON_0001968 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 62-70 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 185-193 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 463-465 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T4 | 565-567 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T5 | 718-720 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T6 | 760-762 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T7 | 1451-1458 | Disease | denotes | sterile | http://purl.obolibrary.org/obo/MONDO_0005047 |
T8 | 1459-1461 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T9 | 1538-1540 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
T10 | 1559-1566 | Disease | denotes | sterile | http://purl.obolibrary.org/obo/MONDO_0005047 |
T11 | 1645-1653 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T12 | 1873-1881 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T13 | 1944-1946 | Disease | denotes | LN | http://purl.obolibrary.org/obo/MONDO_0002486 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-1 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T2 | 81-82 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T3 | 104-107 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T4 | 142-154 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
T5 | 293-298 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T6 | 372-373 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T7 | 374-379 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T8 | 383-384 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T9 | 495-498 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T10 | 540-547 | http://purl.obolibrary.org/obo/UBERON_0000922 | denotes | embryos |
T11 | 601-602 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T12 | 706-711 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T13 | 860-867 | http://purl.obolibrary.org/obo/UBERON_0000922 | denotes | embryos |
T14 | 936-941 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T15 | 1074-1080 | http://www.ebi.ac.uk/efo/EFO_0000984 | denotes | testis |
T16 | 1090-1094 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 3, 4 |
T17 | 1235-1240 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T18 | 1432-1439 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 5]. (2) |
T19 | 1677-1682 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T20 | 1757-1758 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T21 | 1860-1867 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T22 | 1964-1969 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 409-414 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
T2 | 453-461 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
T3 | 463-465 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T5 | 565-567 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T7 | 718-720 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T9 | 760-762 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T11 | 1459-1461 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T13 | 1538-1540 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
T15 | 1944-1946 | Chemical | denotes | LN | http://purl.obolibrary.org/obo/CHEBI_17571|http://purl.obolibrary.org/obo/CHEBI_73529 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 648-655 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
T2 | 1472-1479 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
T3 | 1594-1601 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
T4 | 1733-1740 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-79 | Sentence | denotes | A recommendation for IVF lab practice in light of the current COVID-19 pandemic |
T2 | 81-194 | Sentence | denotes | A global health threat has been declared by the World Health Organization due to the recent outbreak of COVID-19. |
T3 | 195-346 | Sentence | denotes | Although the exact transmission mechanism is yet unknown, it is known that people positive to the virus are contagious due to small aerosols spreading. |
T4 | 347-467 | Sentence | denotes | According to Adrian [1], a virus in a thin layer of (1 μm) of water will vitrify upon cooling into liquid nitrogen (LN). |
T5 | 468-587 | Sentence | denotes | Furthermore, Bielanski [2] has demonstrated that viral contamination of embryos cryopreserved in LN raises real threat. |
T6 | 588-677 | Sentence | denotes | This data is a cause for concern regarding the current cryo-storage practice in IVF labs. |
T7 | 678-763 | Sentence | denotes | If aerosol drops containing virus touch LN, they will vitrify and contaminate the LN. |
T8 | 764-1258 | Sentence | denotes | Four possible scenarios may be possible: (1) vitrified drops can contaminate sperm, oocytes, or embryos which are cryopreserved by open system vitrification, and also, the virus could be transferred to the patient following warming; (2) it can cross-contaminate samples with ACE-2 receptor such as ovarian and testis tissues [3, 4]; (3) it may contaminate the operator upon warming; and (4) it may not cause any contamination if the number of viral load is low or if the virus does not survive. |
T9 | 1259-1606 | Sentence | denotes | In order to overcome the above scenarios, several solutions may be applicable: (1) The use of closed system vitrification systems incorporating CBS straws or other systems [5]. (2) The use of sterile LN and vapor storage [6]. (3) Another option is the use of UV sterilization of LN [7] or the use of sterile liquid air for cooling and storage [8]. |
T10 | 1607-1839 | Sentence | denotes | Finally, if it is true that 15–26% of SARS-CoV-2 patients present the virus in their semen [9], then washing, separation, and storage (quarantine) in a separate container or in special canister [8] should be done as safety measures. |
T11 | 1840-2069 | Sentence | denotes | Until properties of viruses like SARS-CoV-2 are fully investigated with respect to the interaction with LN and reproductive cells and tissues, cautionary measures as those mentioned above should be taken under serious advisement. |
T12 | 2071-2087 | Sentence | denotes | Publisher’s note |
T13 | 2088-2206 | Sentence | denotes | Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. |