PMC:7252096 / 50348-52055
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T643 | 108-113 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
T644 | 173-178 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T645 | 190-206 | Body_part | denotes | nasal epithelium | http://purl.org/sig/ont/fma/fma63140 |
T646 | 196-206 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
T647 | 349-352 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T648 | 369-372 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T649 | 404-409 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T650 | 513-518 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T651 | 546-551 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T652 | 597-601 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T653 | 719-735 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T654 | 730-735 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T655 | 750-755 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T656 | 1014-1019 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T657 | 1134-1136 | Body_part | denotes | v1 | http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614 |
T659 | 1152-1157 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T660 | 1216-1228 | Body_part | denotes | goblet cells | http://purl.org/sig/ont/fma/fma13148 |
T661 | 1223-1228 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T662 | 1246-1251 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T663 | 1301-1306 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T664 | 1357-1362 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
T665 | 1448-1451 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T666 | 1480-1483 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T667 | 1485-1490 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
T668 | 1544-1547 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T669 | 1661-1664 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T102 | 190-206 | Body_part | denotes | nasal epithelium | http://purl.obolibrary.org/obo/UBERON_0005384 |
T103 | 196-206 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T181 | 127-146 | Disease | denotes | Influenza Infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
T182 | 284-292 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T183 | 284-288 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T184 | 1094-1103 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T185 | 1111-1120 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T186 | 1259-1268 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T187 | 1312-1321 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T188 | 1368-1377 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T189 | 1390-1399 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T190 | 1521-1530 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T899 | 108-113 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
T900 | 121-126 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
T901 | 148-149 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T902 | 173-178 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T903 | 184-189 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T904 | 196-206 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
T905 | 217-218 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T906 | 243-244 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T907 | 404-409 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T908 | 479-484 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T909 | 513-518 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T910 | 546-551 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T911 | 576-580 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T912 | 597-606 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell-type |
T913 | 616-621 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T914 | 660-665 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T915 | 719-729 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T916 | 730-735 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T917 | 750-755 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T918 | 873-877 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T919 | 915-916 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T920 | 955-960 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T921 | 1014-1019 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T922 | 1049-1055 | http://purl.obolibrary.org/obo/CLO_0007919 | denotes | n = 18 |
T923 | 1049-1055 | http://purl.obolibrary.org/obo/CLO_0007920 | denotes | n = 18 |
T924 | 1056-1061 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T925 | 1104-1105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T926 | 1109-1110 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T927 | 1152-1157 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T928 | 1223-1228 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T929 | 1246-1251 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T930 | 1301-1306 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T931 | 1357-1362 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
T932 | 1378-1379 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T933 | 1400-1401 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T934 | 1485-1490 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
T935 | 1531-1532 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T936 | 1536-1537 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T937 | 1592-1596 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T938 | 1683-1685 | http://purl.obolibrary.org/obo/CLO_0008933 | denotes | S5 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T54034 | 641-651 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
T98312 | 983-985 | Chemical | denotes | S8 | http://purl.obolibrary.org/obo/CHEBI_29385 |
T31806 | 1295-1300 | Chemical | denotes | Donor | http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891 |
T91641 | 1683-1685 | Chemical | denotes | S5 | http://purl.obolibrary.org/obo/CHEBI_29386 |
T83586 | 1704-1706 | Chemical | denotes | S8 | http://purl.obolibrary.org/obo/CHEBI_29385 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T348 | 147-215 | Sentence | denotes | (A) UMAP of 11,358 single cells from mouse nasal epithelium (n = 4). |
T349 | 216-313 | Sentence | denotes | (B) UMAP projection as in (A), points colored by detection of Ace2 (SARS-CoV-2 receptor homolog). |
T350 | 314-382 | Sentence | denotes | Color coding is as follows: black, RNA positive; blue, RNA negative. |
T351 | 383-486 | Sentence | denotes | (C) Percent of Ace2+ cells by treatment condition (n = 4 arrays per condition; n = 2 arrays per mouse). |
T352 | 487-581 | Sentence | denotes | Black bars indicate Ace2+ cells; white bars indicate Ace2− cells. p = 0.4 by Student’s t test. |
T353 | 582-827 | Sentence | denotes | (D) Heatmap of cell-type-defining genes (Trp63 and Krt17), interferon-induced genes (Irf7, Stat1, Irf9, and Oasl2), and Ace2 among basal epithelial cells, separated by cells derived from saline-treated mice (left) and IFN-α-treated mice (right). |
T354 | 828-914 | Sentence | denotes | Statistical significance by likelihood-ratio test with Bonferroni correction is shown. |
T355 | 915-986 | Sentence | denotes | A full list of differentially expressed genes can be found in Table S8. |
T356 | 987-1159 | Sentence | denotes | (E) Schematic for sampling cells derived from nasal washes of n = 18 human donors with and without current influenza A or B infection for Seq-Well v1 (35,840 single cells). |
T357 | 1160-1183 | Sentence | denotes | See Cao et al., (2020). |
T358 | 1184-1276 | Sentence | denotes | (F and G) ACE2 expression among goblet cells (F) and squamous cells (G) by infection status. |
T359 | 1277-1554 | Sentence | denotes | Shown are Healthy Donor cells from influenza-negative donors (white); Bystander Cells from influenza A (IAV)- or influenza B (IBV)-infected donors, no intracellular viral RNA detected (black); Flu Viral RNA+ Cells with detectable intracellular influenza A or B viral RNA (red). |
T360 | 1555-1666 | Sentence | denotes | Statistical significance by Wilcoxon test with Bonferroni correction, n.s. for Bystander versus Flu Viral RNA+. |
T361 | 1667-1707 | Sentence | denotes | See also Figure S5 and Tables S6 and S8. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1410 | 62-66 | Gene | denotes | Ace2 | Gene:70008 |
1411 | 72-76 | Gene | denotes | ACE2 | Gene:70008 |
1412 | 41-45 | Species | denotes | Mice | Tax:10090 |
1413 | 121-126 | Species | denotes | Human | Tax:9606 |
1414 | 127-136 | Species | denotes | Influenza | Tax:11520 |
1415 | 137-146 | Disease | denotes | Infection | MESH:D007239 |
1417 | 184-189 | Species | denotes | mouse | Tax:10090 |
1420 | 278-282 | Gene | denotes | Ace2 | Gene:59272 |
1421 | 284-294 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1426 | 398-402 | Gene | denotes | Ace2 | Gene:70008 |
1427 | 507-511 | Gene | denotes | Ace2 | Gene:70008 |
1428 | 540-544 | Gene | denotes | Ace2 | Gene:70008 |
1429 | 479-484 | Species | denotes | mouse | Tax:10090 |
1441 | 623-628 | Gene | denotes | Trp63 | Gene:22061 |
1442 | 633-638 | Gene | denotes | Krt17 | Gene:16667 |
1443 | 641-651 | Gene | denotes | interferon | Gene:3439 |
1444 | 667-671 | Gene | denotes | Irf7 | Gene:54123 |
1445 | 673-678 | Gene | denotes | Stat1 | Gene:20846 |
1446 | 680-684 | Gene | denotes | Irf9 | Gene:16391 |
1447 | 690-695 | Gene | denotes | Oasl2 | Gene:23962 |
1448 | 702-706 | Gene | denotes | Ace2 | Gene:70008 |
1449 | 800-805 | Gene | denotes | IFN-α | Gene:111654 |
1450 | 784-788 | Species | denotes | mice | Tax:10090 |
1451 | 814-818 | Species | denotes | mice | Tax:10090 |
1456 | 1125-1136 | Gene | denotes | Seq-Well v1 | |
1457 | 1056-1061 | Species | denotes | human | Tax:9606 |
1458 | 1094-1103 | Species | denotes | influenza | Tax:11520 |
1459 | 1111-1120 | Disease | denotes | infection | MESH:D007239 |
1468 | 1194-1198 | Gene | denotes | ACE2 | Gene:59272 |
1469 | 1312-1321 | Species | denotes | influenza | Tax:11520 |
1470 | 1368-1377 | Species | denotes | influenza | Tax:11520 |
1471 | 1390-1399 | Species | denotes | influenza | Tax:11520 |
1472 | 1521-1530 | Species | denotes | influenza | Tax:11520 |
1473 | 1381-1384 | Species | denotes | IAV | Tax:11320 |
1474 | 1259-1268 | Disease | denotes | infection | MESH:D007239 |
1475 | 1408-1416 | Disease | denotes | infected | MESH:D007239 |