PMC:7252011 / 178-1068
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 12 | 476-507 | Gene | denotes | Angiotensin Converting Enzyme-2 | Gene:59272 |
| 13 | 509-514 | Gene | denotes | ACE-2 | Gene:59272 |
| 14 | 684-689 | Gene | denotes | ACE-2 | Gene:59272 |
| 15 | 60-68 | Species | denotes | patients | Tax:9606 |
| 16 | 335-345 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 17 | 818-826 | Species | denotes | patients | Tax:9606 |
| 18 | 390-401 | Chemical | denotes | Aldosterone | MESH:D000450 |
| 19 | 0-8 | Disease | denotes | Covid-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 261-269 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T2 | 462-474 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T3 | 532-537 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T4 | 728-735 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 234-244 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T2 | 335-343 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 346-349 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T3 | 350-351 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 444-452 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T5 | 532-537 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 844-845 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 378-389 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
| T2 | 390-401 | Chemical | denotes | Aldosterone | http://purl.obolibrary.org/obo/CHEBI_27584 |
| T3 | 462-474 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T4 | 476-487 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
| T5 | 728-735 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 270-285 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 0-151 | Sentence | denotes | Covid-19 is characterized by weak symptoms in most affected patients whilst severe clinical complications, with frequent fatal issues, occur in others. |
| T5 | 152-210 | Sentence | denotes | Disease severity is associated with age and comorbidities. |
| T6 | 211-334 | Sentence | denotes | Understanding of viral infectious mechanisms, and antibody immune response, can help to better control disease progression. |
| T7 | 335-554 | Sentence | denotes | SARS-CoV-2 has a major impact on the Renin Angiotensin Aldosterone System (RAAS), through its binding to the membrane cellular glycoprotein, Angiotensin Converting Enzyme-2 (ACE-2), then infecting cells for replication. |
| T8 | 555-736 | Sentence | denotes | This report hypothesizes the possible implication of an autoimmune response, induced by generation of allo- or autoantibodies to ACE-2, or to its complexes with viral spike protein. |
| T9 | 737-827 | Sentence | denotes | This could contribute to some delayed severe complications occurring in affected patients. |
| T10 | 828-890 | Sentence | denotes | We also propose a strategy for investigating this eventuality. |