PMC:7252009 / 4254-5545 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"87","span":{"begin":774,"end":782},"obj":"Species"},{"id":"88","span":{"begin":1024,"end":1032},"obj":"Species"},{"id":"89","span":{"begin":122,"end":130},"obj":"Disease"},{"id":"90","span":{"begin":527,"end":536},"obj":"Disease"},{"id":"91","span":{"begin":569,"end":604},"obj":"Disease"},{"id":"92","span":{"begin":606,"end":610},"obj":"Disease"},{"id":"93","span":{"begin":635,"end":644},"obj":"Disease"},{"id":"94","span":{"begin":693,"end":701},"obj":"Disease"},{"id":"95","span":{"begin":798,"end":807},"obj":"Disease"},{"id":"96","span":{"begin":872,"end":881},"obj":"Disease"},{"id":"97","span":{"begin":908,"end":954},"obj":"Disease"},{"id":"98","span":{"begin":1041,"end":1050},"obj":"Disease"},{"id":"99","span":{"begin":1125,"end":1129},"obj":"Disease"},{"id":"100","span":{"begin":1156,"end":1164},"obj":"Disease"},{"id":"101","span":{"begin":1169,"end":1173},"obj":"Disease"}],"attributes":[{"id":"A87","pred":"tao:has_database_id","subj":"87","obj":"Tax:9606"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"Tax:9606"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"MESH:C000657245"},{"id":"A90","pred":"tao:has_database_id","subj":"90","obj":"MESH:D011014"},{"id":"A91","pred":"tao:has_database_id","subj":"91","obj":"MESH:D012128"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"MESH:D012128"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"MESH:D000860"},{"id":"A94","pred":"tao:has_database_id","subj":"94","obj":"MESH:C000657245"},{"id":"A95","pred":"tao:has_database_id","subj":"95","obj":"MESH:D000860"},{"id":"A96","pred":"tao:has_database_id","subj":"96","obj":"MESH:D000860"},{"id":"A97","pred":"tao:has_database_id","subj":"97","obj":"MESH:D011665"},{"id":"A98","pred":"tao:has_database_id","subj":"98","obj":"MESH:D000860"},{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"MESH:D012128"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"MESH:C000657245"},{"id":"A101","pred":"tao:has_database_id","subj":"101","obj":"MESH:D012128"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":664,"end":668},"obj":"Body_part"},{"id":"T4","span":{"begin":813,"end":831},"obj":"Body_part"},{"id":"T5","span":{"begin":992,"end":997},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma7158"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T2","span":{"begin":664,"end":668},"obj":"Body_part"},{"id":"T3","span":{"begin":813,"end":831},"obj":"Body_part"},{"id":"T4","span":{"begin":992,"end":997},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0001004"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T20","span":{"begin":122,"end":130},"obj":"Disease"},{"id":"T21","span":{"begin":527,"end":536},"obj":"Disease"},{"id":"T22","span":{"begin":569,"end":604},"obj":"Disease"},{"id":"T23","span":{"begin":575,"end":604},"obj":"Disease"},{"id":"T24","span":{"begin":606,"end":610},"obj":"Disease"},{"id":"T25","span":{"begin":693,"end":701},"obj":"Disease"},{"id":"T26","span":{"begin":1125,"end":1129},"obj":"Disease"},{"id":"T27","span":{"begin":1156,"end":1164},"obj":"Disease"},{"id":"T28","span":{"begin":1169,"end":1173},"obj":"Disease"}],"attributes":[{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A21","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T18","span":{"begin":152,"end":153},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T19","span":{"begin":664,"end":668},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T20","span":{"begin":664,"end":668},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T21","span":{"begin":727,"end":732},"obj":"http://purl.obolibrary.org/obo/UBERON_0001456"},{"id":"T22","span":{"begin":813,"end":831},"obj":"http://purl.obolibrary.org/obo/UBERON_0001004"},{"id":"T23","span":{"begin":992,"end":997},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T24","span":{"begin":992,"end":997},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T25","span":{"begin":1095,"end":1096},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":1015,"end":1020},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T4","span":{"begin":938,"end":954},"obj":"http://purl.obolibrary.org/obo/GO_0042310"},{"id":"T5","span":{"begin":968,"end":978},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-sentences","denotations":[{"id":"T16","span":{"begin":0,"end":117},"obj":"Sentence"},{"id":"T17","span":{"begin":118,"end":447},"obj":"Sentence"},{"id":"T18","span":{"begin":448,"end":680},"obj":"Sentence"},{"id":"T19","span":{"begin":681,"end":768},"obj":"Sentence"},{"id":"T20","span":{"begin":769,"end":1003},"obj":"Sentence"},{"id":"T21","span":{"begin":1004,"end":1291},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":527,"end":536},"obj":"Phenotype"},{"id":"T9","span":{"begin":575,"end":595},"obj":"Phenotype"},{"id":"T10","span":{"begin":635,"end":644},"obj":"Phenotype"},{"id":"T11","span":{"begin":798,"end":807},"obj":"Phenotype"},{"id":"T12","span":{"begin":872,"end":881},"obj":"Phenotype"},{"id":"T13","span":{"begin":1041,"end":1050},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0012418"}],"text":"Fourth and finally, this pandemic reinforces the importance for physical therapists to remain scientifically updated. The COVID-19 pandemic resulted in a significant increase in the number of studies reporting the impact of the disease9; despite that, the pulmonary repercussion of the disease remains poorly known.12 The difficulty in understanding how to offer optimal ventilatory support was the primary barrier for the CRI Physical Therapists. The previous professional experience was to administer ventilatory support for pneumonia based on the pathophysiology of Acute Respiratory Distress Syndrome (ARDS), where the severity of hypoxemia is associated with lung compliance. However, in COVID-19, CRI Physical Therapists faced, at least, two distinct phenotypes. Some patients present severe hypoxemia with respiratory system compliance remaining near normal, where hypoxemia seems to occur due to the loss of the hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. In another group of patients, severe hypoxemia is associated with lower compliance values, a condition similar to severe ARDS.12 The difference between COVID-19 and ARDS required CRI Physical Therapists to be updated almost daily to understand how to give the proper ventilatory support."}