> top > docs > PMC:7247521 > spans > 9867-10597 > annotations

PMC:7247521 / 9867-10597 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
153 535-539 Gene denotes OCT2 Gene:6582
154 604-608 Gene denotes hERG Gene:2078
155 622-626 Gene denotes hERG Gene:2078
156 646-649 Species denotes rat Tax:10116
157 555-563 Disease denotes toxicity MESH:D064420
158 570-578 Disease denotes toxicity MESH:D064420
159 656-664 Disease denotes toxicity MESH:D064420
160 673-687 Disease denotes hepatotoxicity MESH:D056486
161 689-707 Disease denotes skin sensitisation MESH:D012871
162 720-728 Disease denotes toxicity MESH:D064420
163 344-350 CellLine denotes Caco-2 CVCL:0025

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T100 242-257 CHEBI:52217;CHEBI:52217 denotes pharmacokinetic
T101 344-350 CL_1 denotes Caco-2
T102 436-455 UBERON:0000120 denotes blood-brain barrier
T103 460-482 UBERON:0001017 denotes central nervous system
T104 498-507 GO:0007588 denotes excretion
T105 529-534 UBERON:0002113 denotes renal
T106 535-539 PR:000013036 denotes OCT2
T107 565-569 CHEBI:34018;CHEBI:34018 denotes AMES
T108 604-608 PR:P11308 denotes hERG
T109 611-620 CHEBI:35222;CHEBI:35222 denotes inhibitor
T110 622-626 PR:P11308 denotes hERG
T111 630-639 CHEBI:35222;CHEBI:35222 denotes inhibitor
T112 641-645 UBERON:0000165 denotes oral
T113 646-649 NCBITaxon:10114 denotes rat

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T13 351-355 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 378-382 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T15 436-441 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T16 442-447 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T17 460-482 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T18 689-693 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T7 378-382 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T8 436-455 Body_part denotes blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T9 436-441 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T10 442-447 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T11 460-482 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T12 468-482 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T13 689-693 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T67 76-82 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T68 307-309 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T69 344-355 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2 cell
T70 378-382 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T71 378-382 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T72 378-382 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T73 378-382 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T74 378-382 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T75 436-441 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T76 436-441 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T77 442-447 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T78 442-447 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T79 460-482 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T80 460-482 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T81 460-482 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T82 689-693 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T83 689-693 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T84 689-693 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T85 689-693 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T86 689-693 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T44 137-139 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T45 611-620 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T46 627-629 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T47 630-639 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T28 498-507 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T64 0-233 Sentence denotes Based on the SwissADME database [21], the physicochemical properties of the active components was predicted, including molecular weight (MW), rotatable bonds count, H-bond acceptors and donors count, TPSA and leadlikeness violations.
T65 234-730 Sentence denotes Second, pharmacokinetic properties was predicted through pkCSM database [22], which contained the absorption (Caco-2 cell permeability, HIA and skin permeability), distribution (VDss, unbound fraction, blood-brain barrier and central nervous system permeability), excretion (total clearance and renal OCT2 substrate) and toxicity (AMES toxicity, maximum tolerated dose, hERG I inhibitor, hERG II inhibitor, oral rat acute toxicity (LD50), hepatotoxicity, skin sensitisation, and minnow toxicity).

2_test

Id Subject Object Predicate Lexical cue
32554251-28256516-6393500 33-35 28256516 denotes 21
32554251-25860834-6393501 307-309 25860834 denotes 22