PMC:7247521 / 915-1810
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
28 | 63-67 | Gene | denotes | PPAR | Gene:5465 |
29 | 233-239 | Gene | denotes | MIR183 | Gene:406959 |
30 | 250-254 | Gene | denotes | CDK7 | Gene:1022 |
31 | 341-345 | Gene | denotes | ACE2 | Gene:59272 |
32 | 745-754 | Gene | denotes | X2 and O2 | |
34 | 862-871 | Species | denotes | 2019-nCov | Tax:2697049 |
37 | 41-48 | Chemical | denotes | steroid | MESH:D013256 |
38 | 501-506 | Chemical | denotes | ADMET | |
40 | 127-139 | Disease | denotes | TTD diseases | MESH:D003141 |
41 | 149-170 | Disease | denotes | inflammatory diseases | MESH:D007249 |
42 | 172-178 | Disease | denotes | asthma | MESH:D001249 |
43 | 180-217 | Disease | denotes | chronic obstructive pulmonary Disease | MESH:D029424 |
44 | 327-336 | Disease | denotes | pneumonia | MESH:D011014 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T21 | 41-48 | CHEBI:35341;CHEBI:35341;GO:0006694 | denotes | steroid |
T22 | 49-61 | GO:0006694 | denotes | biosynthesis |
T23 | 200-209 | UBERON:0002048 | denotes | pulmonary |
T24 | 226-231 | SO:0000276 | denotes | miRNA |
T25 | 250-254 | PR:000005265 | denotes | CDK7 |
T26 | 341-345 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T27 | 349-359 | GO:0010467 | denotes | expression |
T28 | 534-543 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
T29 | 598-602 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T30 | 627-643 | UBERON:0001555 | denotes | gastrointestinal |
T31 | 752-754 | CHEBI:15379;CHEBI:15379 | denotes | O2 |
T32 | 862-871 | SP_7 | denotes | 2019-nCov |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T2 | 360-368 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T6 | 149-170 | Disease | denotes | inflammatory diseases | http://purl.obolibrary.org/obo/MONDO_0021166 |
T7 | 172-178 | Disease | denotes | asthma | http://purl.obolibrary.org/obo/MONDO_0004979 |
T8 | 180-217 | Disease | denotes | chronic obstructive pulmonary Disease | http://purl.obolibrary.org/obo/MONDO_0005002 |
T9 | 327-336 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T7 | 68-77 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
T8 | 101-110 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
T9 | 468-474 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T10 | 612-616 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T11 | 741-743 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T12 | 782-785 | http://purl.obolibrary.org/obo/CLO_0007875 | denotes | MS1 |
T13 | 782-785 | http://purl.obolibrary.org/obo/CLO_0052410 | denotes | MS1 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T3 | 41-48 | Chemical | denotes | steroid | http://purl.obolibrary.org/obo/CHEBI_35341 |
T4 | 127-130 | Chemical | denotes | TTD | http://purl.obolibrary.org/obo/CHEBI_73659 |
T5 | 260-262 | Chemical | denotes | TF | http://purl.obolibrary.org/obo/CHEBI_74862 |
T6 | 360-368 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T7 | 598-602 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T8 | 737-739 | Chemical | denotes | M3 | http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453 |
T10 | 752-754 | Chemical | denotes | O2 | http://purl.obolibrary.org/obo/CHEBI_15379 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 172-178 | Phenotype | denotes | asthma | http://purl.obolibrary.org/obo/HP_0002099 |
T2 | 180-217 | Phenotype | denotes | chronic obstructive pulmonary Disease | http://purl.obolibrary.org/obo/HP_0006510 |
T3 | 327-336 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 41-61 | http://purl.obolibrary.org/obo/GO_0006694 | denotes | steroid biosynthesis |
T6 | 49-61 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | biosynthesis |
T7 | 63-85 | http://purl.obolibrary.org/obo/GO_0035357 | denotes | PPAR signaling pathway |
T8 | 68-85 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
T9 | 68-77 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T10 | 87-118 | http://purl.obolibrary.org/obo/GO_0033211 | denotes | adipocytokine signaling pathway |
T11 | 87-118 | http://purl.obolibrary.org/obo/GO_0033210 | denotes | adipocytokine signaling pathway |
T12 | 87-118 | http://purl.obolibrary.org/obo/GO_0033209 | denotes | adipocytokine signaling pathway |
T13 | 101-118 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
T14 | 101-110 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T15 | 260-262 | http://purl.obolibrary.org/obo/GO_0000981 | denotes | TF |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13 | 270-369 | Sentence | denotes | QFPD contained 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. |
T14 | 370-487 | Sentence | denotes | Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. |
T15 | 488-702 | Sentence | denotes | In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high gastrointestinal absorption and the median lethal dose (LD50 > 1600 mg/kg). |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T1 | 798-801 | GlycoEpitope | denotes | WO1 | http://www.glycoepitope.jp/epitopes/AN0690 |