PMC:7247521 / 686-1377
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 28 | 292-296 | Gene | denotes | PPAR | Gene:5465 |
| 29 | 462-468 | Gene | denotes | MIR183 | Gene:406959 |
| 30 | 479-483 | Gene | denotes | CDK7 | Gene:1022 |
| 31 | 570-574 | Gene | denotes | ACE2 | Gene:59272 |
| 33 | 177-191 | Gene | denotes | oxidoreductase | Gene:8630 |
| 35 | 125-128 | Chemical | denotes | FUs | |
| 36 | 202-207 | Chemical | denotes | lipid | MESH:D008055 |
| 37 | 270-277 | Chemical | denotes | steroid | MESH:D013256 |
| 40 | 356-368 | Disease | denotes | TTD diseases | MESH:D003141 |
| 41 | 378-399 | Disease | denotes | inflammatory diseases | MESH:D007249 |
| 42 | 401-407 | Disease | denotes | asthma | MESH:D001249 |
| 43 | 409-446 | Disease | denotes | chronic obstructive pulmonary Disease | MESH:D029424 |
| 44 | 556-565 | Disease | denotes | pneumonia | MESH:D011014 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T18 | 202-207 | CHEBI:18059;CHEBI:18059;GO:0006629 | denotes | lipid |
| T19 | 208-225 | GO:0006629 | denotes | metabolic process |
| T20 | 227-246 | GO:0042592 | denotes | homeostatic process |
| T21 | 270-277 | CHEBI:35341;CHEBI:35341;GO:0006694 | denotes | steroid |
| T22 | 278-290 | GO:0006694 | denotes | biosynthesis |
| T23 | 429-438 | UBERON:0002048 | denotes | pulmonary |
| T24 | 455-460 | SO:0000276 | denotes | miRNA |
| T25 | 479-483 | PR:000005265 | denotes | CDK7 |
| T26 | 570-574 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T27 | 578-588 | GO:0010467 | denotes | expression |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 202-207 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T2 | 589-597 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T6 | 378-399 | Disease | denotes | inflammatory diseases | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T7 | 401-407 | Disease | denotes | asthma | http://purl.obolibrary.org/obo/MONDO_0004979 |
| T8 | 409-446 | Disease | denotes | chronic obstructive pulmonary Disease | http://purl.obolibrary.org/obo/MONDO_0005002 |
| T9 | 556-565 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 192-200 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T7 | 297-306 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T8 | 330-339 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 70-78 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T2 | 202-207 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T3 | 270-277 | Chemical | denotes | steroid | http://purl.obolibrary.org/obo/CHEBI_35341 |
| T4 | 356-359 | Chemical | denotes | TTD | http://purl.obolibrary.org/obo/CHEBI_73659 |
| T5 | 489-491 | Chemical | denotes | TF | http://purl.obolibrary.org/obo/CHEBI_74862 |
| T6 | 589-597 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 401-407 | Phenotype | denotes | asthma | http://purl.obolibrary.org/obo/HP_0002099 |
| T2 | 409-446 | Phenotype | denotes | chronic obstructive pulmonary Disease | http://purl.obolibrary.org/obo/HP_0006510 |
| T3 | 556-565 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 192-225 | http://purl.obolibrary.org/obo/GO_0045834 | denotes | activity, lipid metabolic process |
| T2 | 202-225 | http://purl.obolibrary.org/obo/GO_0006629 | denotes | lipid metabolic process |
| T3 | 208-225 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolic process |
| T4 | 227-246 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostatic process |
| T5 | 270-290 | http://purl.obolibrary.org/obo/GO_0006694 | denotes | steroid biosynthesis |
| T6 | 278-290 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | biosynthesis |
| T7 | 292-314 | http://purl.obolibrary.org/obo/GO_0035357 | denotes | PPAR signaling pathway |
| T8 | 297-314 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
| T9 | 297-306 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T10 | 316-347 | http://purl.obolibrary.org/obo/GO_0033211 | denotes | adipocytokine signaling pathway |
| T11 | 316-347 | http://purl.obolibrary.org/obo/GO_0033210 | denotes | adipocytokine signaling pathway |
| T12 | 316-347 | http://purl.obolibrary.org/obo/GO_0033209 | denotes | adipocytokine signaling pathway |
| T13 | 330-347 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
| T14 | 330-339 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T15 | 489-491 | http://purl.obolibrary.org/obo/GO_0000981 | denotes | TF |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T12 | 80-498 | Sentence | denotes | The corresponding common targets of the five FUs were all significantly enriched in Go Ontology (oxidoreductase activity, lipid metabolic process, homeostatic process, etc.), KEGG pathways (steroid biosynthesis, PPAR signaling pathway, adipocytokine signaling pathway, etc.), TTD diseases (chronic inflammatory diseases, asthma, chronic obstructive pulmonary Disease, etc.), miRNA (MIR183), kinase (CDK7) and TF (LXR). |
| T13 | 499-598 | Sentence | denotes | QFPD contained 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. |