PMC:7247521 / 5449-6439 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"107","span":{"begin":125,"end":133},"obj":"Disease"},{"id":"108","span":{"begin":876,"end":884},"obj":"Disease"},{"id":"109","span":{"begin":960,"end":968},"obj":"Disease"}],"attributes":[{"id":"A107","pred":"tao:has_database_id","subj":"107","obj":"MESH:C000657245"},{"id":"A108","pred":"tao:has_database_id","subj":"108","obj":"MESH:C000657245"},{"id":"A109","pred":"tao:has_database_id","subj":"109","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T73","span":{"begin":125,"end":133},"obj":"SP_7"},{"id":"T74","span":{"begin":149,"end":164},"obj":"CHEBI:52217;CHEBI:52217"},{"id":"T75","span":{"begin":243,"end":255},"obj":"CHEBI:52217;CHEBI:52217"},{"id":"T76","span":{"begin":317,"end":322},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T77","span":{"begin":460,"end":472},"obj":"CHEBI:52217;CHEBI:52217"},{"id":"T78","span":{"begin":876,"end":884},"obj":"SP_7"},{"id":"T79","span":{"begin":960,"end":968},"obj":"SP_7"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T28","span":{"begin":125,"end":133},"obj":"Disease"},{"id":"T29","span":{"begin":876,"end":884},"obj":"Disease"},{"id":"T30","span":{"begin":960,"end":968},"obj":"Disease"}],"attributes":[{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T45","span":{"begin":14,"end":15},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T46","span":{"begin":257,"end":258},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T47","span":{"begin":360,"end":361},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T48","span":{"begin":830,"end":832},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T21","span":{"begin":317,"end":322},"obj":"Chemical"},{"id":"T22","span":{"begin":418,"end":421},"obj":"Chemical"},{"id":"T23","span":{"begin":506,"end":509},"obj":"Chemical"},{"id":"T24","span":{"begin":610,"end":613},"obj":"Chemical"}],"attributes":[{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_145500"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_145500"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_145500"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T36","span":{"begin":0,"end":234},"obj":"Sentence"},{"id":"T37","span":{"begin":235,"end":392},"obj":"Sentence"},{"id":"T38","span":{"begin":393,"end":664},"obj":"Sentence"},{"id":"T39","span":{"begin":665,"end":834},"obj":"Sentence"},{"id":"T40","span":{"begin":835,"end":990},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}

{"project":"2_test","denotations":[{"id":"32554251-17921993-6393489","span":{"begin":389,"end":390},"obj":"17921993"},{"id":"32554251-17318209-6393490","span":{"begin":830,"end":832},"obj":"17318209"},{"id":"32554251-30809144-6393491","span":{"begin":986,"end":988},"obj":"30809144"}],"text":"QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula. Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8]. Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10]. More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11]. So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12]."}