PMC:7247521 / 36383-37273 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"570","span":{"begin":8,"end":12},"obj":"Gene"},{"id":"571","span":{"begin":17,"end":22},"obj":"Gene"},{"id":"572","span":{"begin":91,"end":95},"obj":"Gene"},{"id":"573","span":{"begin":100,"end":105},"obj":"Gene"},{"id":"574","span":{"begin":323,"end":327},"obj":"Gene"},{"id":"575","span":{"begin":365,"end":370},"obj":"Gene"},{"id":"576","span":{"begin":413,"end":417},"obj":"Gene"},{"id":"577","span":{"begin":312,"end":321},"obj":"Disease"},{"id":"578","span":{"begin":441,"end":448},"obj":"Disease"},{"id":"579","span":{"begin":472,"end":479},"obj":"Disease"}],"attributes":[{"id":"A570","pred":"tao:has_database_id","subj":"570","obj":"Gene:59272"},{"id":"A571","pred":"tao:has_database_id","subj":"571","obj":"Gene:682"},{"id":"A572","pred":"tao:has_database_id","subj":"572","obj":"Gene:59272"},{"id":"A573","pred":"tao:has_database_id","subj":"573","obj":"Gene:682"},{"id":"A574","pred":"tao:has_database_id","subj":"574","obj":"Gene:59272"},{"id":"A575","pred":"tao:has_database_id","subj":"575","obj":"Gene:682"},{"id":"A576","pred":"tao:has_database_id","subj":"576","obj":"Gene:59272"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"MESH:D011014"},{"id":"A578","pred":"tao:has_database_id","subj":"578","obj":"MESH:D003110"},{"id":"A579","pred":"tao:has_database_id","subj":"579","obj":"MESH:D003110"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T138","span":{"begin":41,"end":48},"obj":"Body_part"},{"id":"T139","span":{"begin":127,"end":134},"obj":"Body_part"},{"id":"T140","span":{"begin":244,"end":251},"obj":"Body_part"},{"id":"T141","span":{"begin":270,"end":278},"obj":"Body_part"},{"id":"T142","span":{"begin":449,"end":465},"obj":"Body_part"},{"id":"T143","span":{"begin":460,"end":465},"obj":"Body_part"},{"id":"T144","span":{"begin":552,"end":560},"obj":"Body_part"},{"id":"T145","span":{"begin":617,"end":621},"obj":"Body_part"},{"id":"T146","span":{"begin":731,"end":739},"obj":"Body_part"}],"attributes":[{"id":"A138","pred":"fma_id","subj":"T138","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A139","pred":"fma_id","subj":"T139","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A140","pred":"fma_id","subj":"T140","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A145","pred":"fma_id","subj":"T145","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A146","pred":"fma_id","subj":"T146","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T67","span":{"begin":312,"end":321},"obj":"Disease"}],"attributes":[{"id":"A67","pred":"mondo_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T316","span":{"begin":67,"end":72},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T317","span":{"begin":74,"end":75},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T318","span":{"begin":253,"end":254},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T319","span":{"begin":342,"end":347},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T320","span":{"begin":385,"end":390},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T321","span":{"begin":432,"end":437},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T322","span":{"begin":441,"end":448},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T323","span":{"begin":449,"end":459},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T324","span":{"begin":460,"end":465},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T316","span":{"begin":176,"end":180},"obj":"Chemical"},{"id":"T317","span":{"begin":270,"end":278},"obj":"Chemical"},{"id":"T318","span":{"begin":552,"end":560},"obj":"Chemical"},{"id":"T319","span":{"begin":570,"end":575},"obj":"Chemical"},{"id":"T320","span":{"begin":731,"end":739},"obj":"Chemical"}],"attributes":[{"id":"A316","pred":"chebi_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/CHEBI_22695"},{"id":"A317","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A318","pred":"chebi_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A319","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A320","pred":"chebi_id","subj":"T320","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T19","span":{"begin":312,"end":321},"obj":"Phenotype"}],"attributes":[{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}

{"project":"LitCovid-sentences","denotations":[{"id":"T265","span":{"begin":0,"end":73},"obj":"Sentence"},{"id":"T266","span":{"begin":74,"end":76},"obj":"Sentence"},{"id":"T267","span":{"begin":77,"end":135},"obj":"Sentence"},{"id":"T268","span":{"begin":136,"end":193},"obj":"Sentence"},{"id":"T269","span":{"begin":194,"end":252},"obj":"Sentence"},{"id":"T270","span":{"begin":253,"end":255},"obj":"Sentence"},{"id":"T271","span":{"begin":256,"end":481},"obj":"Sentence"},{"id":"T272","span":{"begin":482,"end":580},"obj":"Sentence"},{"id":"T273","span":{"begin":581,"end":670},"obj":"Sentence"},{"id":"T274","span":{"begin":671,"end":890},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes. A: Radar plot of ACE2 and CD147 expression across 53 tissues. The expression values were converted to base-2 logarithm. Red triangle and square mean the top 5 expression tissues. B: UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic). The horizontal bar graph at the bottom left shows the total number of proteins for each group set. Circles and vertical lines in the x-axis mark the corresponding data sets being compared. The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)"}