PMC:7247521 / 31632-32967
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
480 | 278-286 | Gene | denotes | Helicase | Gene:164045 |
481 | 947-951 | Gene | denotes | Mpro | Gene:8673700 |
482 | 1175-1179 | Gene | denotes | Mpro | Gene:8673700 |
483 | 730-735 | Gene | denotes | PLpro | Gene:43740578 |
484 | 506-514 | Gene | denotes | Helicase | Gene:164045 |
485 | 173-176 | Chemical | denotes | TYR | MESH:D014443 |
486 | 181-184 | Chemical | denotes | ALA | MESH:D000409 |
487 | 189-192 | Chemical | denotes | ILE | MESH:D007532 |
488 | 200-203 | Chemical | denotes | PRO | MESH:D011392 |
489 | 378-381 | Chemical | denotes | ASN | MESH:D001216 |
490 | 387-390 | Chemical | denotes | ARG | MESH:D001120 |
491 | 396-399 | Chemical | denotes | LEU | MESH:D007930 |
492 | 407-410 | Chemical | denotes | PRO | MESH:D011392 |
493 | 992-1000 | Chemical | denotes | hydrogen | MESH:D006859 |
494 | 1055-1058 | Chemical | denotes | GLU | MESH:D018698 |
495 | 1064-1067 | Chemical | denotes | LEU | MESH:D007930 |
496 | 1076-1079 | Chemical | denotes | CYS | MESH:D003545 |
497 | 1090-1092 | Chemical | denotes | O2 | MESH:D010100 |
498 | 1211-1217 | Chemical | denotes | Carbon | MESH:D002244 |
499 | 1218-1226 | Chemical | denotes | hydrogen | MESH:D006859 |
500 | 1236-1241 | Chemical | denotes | anion | MESH:D000838 |
501 | 1246-1252 | Chemical | denotes | sulfur | MESH:D013455 |
502 | 1302-1305 | Chemical | denotes | GLY | |
503 | 1310-1313 | Chemical | denotes | LEU | MESH:D007930 |
504 | 1322-1325 | Chemical | denotes | CYS | MESH:D003545 |
505 | 911-914 | Disease | denotes | XCH |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T401 | 25-33 | CHEBI:36357;CHEBI:36357 | denotes | compound |
T402 | 83-92 | PG_2 | denotes | E protein |
T403 | 94-97 | CHEBI:24870;CHEBI:24870 | denotes | ion |
T404 | 441-449 | CHEBI:36357;CHEBI:36357 | denotes | compound |
T405 | 499-504 | PR:000000125 | denotes | nsp13 |
T406 | 571-576 | CHEBI:32988;CHEBI:32988 | denotes | Amide |
T407 | 749-754 | CHEBI:22563;CHEBI:22563 | denotes | anion |
T408 | 890-898 | CHEBI:36357;CHEBI:36357 | denotes | compound |
T409 | 1090-1092 | CHEBI:15379;CHEBI:15379 | denotes | O2 |
T410 | 1115-1123 | CHEBI:36357;CHEBI:36357 | denotes | compound |
T411 | 1236-1241 | CHEBI:22563;CHEBI:22563 | denotes | anion |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T107 | 85-92 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T255 | 14-15 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T256 | 416-418 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T257 | 430-431 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T258 | 687-689 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T259 | 879-880 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T260 | 1104-1105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T261 | 1306-1308 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T217 | 0-2 | Chemical | denotes | M3 | http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453 |
T219 | 85-92 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T220 | 94-97 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
T221 | 117-119 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T222 | 127-129 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T223 | 181-184 | Chemical | denotes | ALA | http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432 |
T225 | 228-230 | Chemical | denotes | M3 | http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453 |
T227 | 319-324 | Chemical | denotes | Donor | http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891 |
T229 | 325-330 | Chemical | denotes | Donor | http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891 |
T231 | 332-334 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T232 | 378-381 | Chemical | denotes | ASN | http://purl.obolibrary.org/obo/CHEBI_22653 |
T233 | 515-518 | Chemical | denotes | ADP | http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342 |
T236 | 571-576 | Chemical | denotes | Amide | http://purl.obolibrary.org/obo/CHEBI_32988 |
T237 | 577-579 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T238 | 592-594 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T239 | 628-631 | Chemical | denotes | ALA | http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432 |
T241 | 746-748 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T242 | 749-754 | Chemical | denotes | anion | http://purl.obolibrary.org/obo/CHEBI_22563 |
T243 | 756-758 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T244 | 759-761 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T245 | 771-773 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T246 | 774-776 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T247 | 790-792 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T248 | 983-985 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T249 | 986-991 | Chemical | denotes | Donor | http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891 |
T251 | 992-1000 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
T252 | 1010-1012 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T253 | 1090-1092 | Chemical | denotes | O2 | http://purl.obolibrary.org/obo/CHEBI_15379 |
T254 | 1211-1217 | Chemical | denotes | Carbon | http://purl.obolibrary.org/obo/CHEBI_27594 |
T255 | 1218-1226 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
T256 | 1233-1235 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T257 | 1236-1241 | Chemical | denotes | anion | http://purl.obolibrary.org/obo/CHEBI_22563 |
T258 | 1243-1245 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
T259 | 1246-1252 | Chemical | denotes | sulfur | http://purl.obolibrary.org/obo/CHEBI_26833 |
T260 | 1257-1259 | Chemical | denotes | Pi | http://purl.obolibrary.org/obo/CHEBI_35780 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T102 | 94-105 | http://purl.obolibrary.org/obo/GO_0022831 | denotes | ion channel |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T247 | 0-415 | Sentence | denotes | M3 (Fig. 8A), a specific compound in formulae MXSG, showed eight interactions with E protein [ion channel] including Pi-sigma, Pi-alkyl and Alkyl, which were connected with TYR 57, ALA 32, ILE 46 and PRO 54, etc.; additionally, M3 (Fig. 8B) showed five interactions with nsp13 [Helicase NCB site] including Unfavorable Donor-Donor, Pi-alkyl and Alkyl, which were connected with ASN 559, ARG 409, LEU 42 and PRO 406. |
T248 | 416-864 | Sentence | denotes | S1 (Fig. 8C), a specific compound in formulae SGMH, showed seven interactions with nsp13 [Helicase ADP site] including H-bond interactions, van der waals, Amide-Pi stacked and Pi-alkyl, which were connected with ALA 313, ASP 374, GLN 537 and SER 289, etc.; additionally, S1 (Fig. 8D) showed five interactions with PLpro including Pi-anion, Pi-Pi stacked, Pi-Pi T-shaped and Pi-alkyl, which were connected with TYR 264, ASP 164, TYR 268 and PRO 248. |
T249 | 865-1089 | Sentence | denotes | X2 (Fig. 8E), a specific compound in formulae XCH, showed seven interactions with Mpro including H-bond interactions, Pi-Donor hydrogen bond and Pi-alkyl, which were connected with MET 165, GLU 166, LEU 141 and CYS 145, etc. |
T250 | 1090-1335 | Sentence | denotes | O2 (Fig. 8F), a specific compound in formulae Others, showed seven interactions with Mpro including H-bond interactions, Carbon hydrogen bond, Pi-anion, Pi-sulfur and Pi-alkyl, which were connected with MET 131, GLY 71, LEU 100 and CYS 115, etc. |