PMC:7247521 / 23999-25288 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7247521","sourcedb":"PMC","sourceid":"7247521","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7247521","text":"After using the BATMAN-TCM, we constructed five ingredients-target-pathway-disease networks, including MSXG, SGMH, XCH, WLS and Others. In order to emphasize the important network elements, we showed the networks that exhibit those targets with larger than 6, 5, 8, 7 and 4 linking compounds for MSXG, SGMH, XCH, WLS and Others, respectively (Fig. 6 ). MSXG network contained 31 key components, 50 proteins and 17 pathways; SGMH network contained 15 key components, 20 proteins and 8 pathways; WLS network contained 18 key components, 9 proteins and 4 pathways; XCH network contained 32 key components, 15 proteins and 12 pathways; Others network contained 10 key components, 13 proteins and 3 pathways. To find the potential drugs of formulae QFPD for COVID-19, a total of 67 hub components were used for ADMET analysis.\nFig. 6 The component-target-pathway-disease network. Purple polygons: PubChem ID of QFPD compounds; blue pentagrams: QFPD targets; yellow circles: KEGG pathway; red square: Therapeutic Target Database (TTD) disease term, green square: Online Mendelian Inheritance in Man (OMIN) disease term. A: MXSG, B: SGMH, C: WLS, D: XCH, E: Others. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this 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